Nasturtium + Esketamine
Esketamine brand name: Spravato.
We found no known interaction between Nasturtium and Esketamine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Nasturtium and Esketamine
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Esketamine and Nasturtium in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Nasturtium at all — not against Esketamine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Nasturtium safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
See Every Supplement That Interacts With Esketamine
This page covers Nasturtium only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Esketamine page lists 11 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Scopolia (major), Cowhage (moderate), Dhea (moderate), Griffonia Simplicifolia (moderate) and Indian Snakeroot (moderate).
By severity: 1 major · 6 moderate · 4 minor.
From our pharmacist’s overview on the Esketamine page
“Esketamine (Spravato) is the nasal spray for depression that hasn't responded to standard treatment, and its supplement list deserves genuine respect. Scopolia carries the only major rating and is the entry to understand before any other; pairing it with the medication can raise the risk of anticholinergic effects, meaning dry mouth, b…”
Reviewed by 2 · Jul 18, 2026
Taking Nasturtium as Part of a Dietary Supplement Product? Check It for Interactions
We hold 3 real supplement products containing Nasturtium, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Nasturtium. Even though Nasturtium itself has no known interaction with Esketamine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Nasturtium and Esketamine Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#405 of 1,452 supplements looked up here in the last 7 days
#1,878 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Nasturtium reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Nasturtium and Esketamine records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Nasturtium
What is Nasturtium?
- Urinary tract infections
- Respiratory infections and congestion
- Antimicrobial support
- Wound and skin care (topical)
- Mild cold and cough symptoms
Nasturtium is an edible garden plant traditionally used for urinary and respiratory infections, often combined with horseradish in herbal products. Some lab studies suggest it has antimicrobial activity, but high-quality human evidence is limited. Talk with your pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have kidney or stomach problems.
Tropaeolum majus · Tropaeolaceae · Leaves, flowers, and seeds · Fresh leaves and flowers (food/salad), dried herb, tea, capsules, tinctures, and combination herbal products
An interaction check asks whether these two react with each other — it does not ask whether Nasturtium is a good idea for someone in your situation. Here is what our Nasturtium record says about it on its own.
Nasturtium: dosing
There is no well-established standardized dose for nasturtium. Amounts vary widely depending on whether you use fresh leaves, dried herb, tea, capsules, or a combination product.The best approach is to follow the directions on the product label and not exceed the recommended amount.
From our Nasturtium monograph — the full record covers uses, side effects and every documented interaction.
About Esketamine Nasal Spray
What Is Esketamine Nasal Spray Used For?
Brand name: Spravato
Spravato nasal spray is approved for two uses in adults. First, it treats treatment-resistant depression (TRD) — depression that has not responded to other antidepressants — either on its own or alongside an oral antidepressant. Second, it treats depressive symptoms in adults with major depressive disorder (MDD) who have acute suicidal ideation or behavior, always used together with an oral antidepressant in this case.
Important limits: Spravato has not been shown to prevent suicide or reduce suicidal thoughts or behavior on its own. It is not a replacement for hospitalization if that is clinically needed, and it is not approved as an anesthetic.
Most-Reported Side Effects for Esketamine
From FAERS, the FDA’s public side-effect reporting system (17,728 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Nasturtium
Browse every other medication we’ve checked against Nasturtium — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Nasturtium against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Losartan Potassium ›
- Testosterone ›
- Ivermectin ›
- Abemaciclib ›
- Aspirin ›
- Metoprolol ›
- Acetaminophen ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Tadalafil ›
- Docusate ›
- Tirzepatide ›
- Ibuprofen ›
- Methamphetamine ›
- Hydroxyurea ›
- Warfarin Sodium ›
- Valacyclovir ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Lisdexamfetamine ›
- Propranolol ›
- Metformin ›
- Amitriptyline ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Methotrexate ›
- Amlodipine Besylate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Fluoxetine ›
- Doxycycline ›
- Acyclovir ›
- Azithromycin ›
- Lamotrigine ›
- Pregabalin ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Quetiapine ›
- Clonazepam ›
- Levothyroxine, Liothyronine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Methylene Blue ›
- Duloxetine ›
- Citalopram ›
- Buspirone ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Nasturtium list.
Nasturtium References
The 5 references that drive our Nasturtium monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Fintelmann V, Albrecht U, Schmitz G, Schnitker J. Efficacy and safety of a combination herbal medicinal product containing Tropaeoli majoris herba and Armoraciae rusticanae radix for the prophylactic treatment of patients with respiratory tract diseases:
- Albrecht U, Goos KH, Schneider B. A randomised, double-blind, placebo-controlled trial of a herbal medicinal product containing Tropaeoli majoris herba (Nasturtium) and Armoraciae rusticanae radix (Horseradish) for the prophylactic treatment of patients w
- Perez-Crespo M, Silvestre JF, Mataix J, Ballester I, Toledo F, Betlloch I. Contact dermatitis due to nasturtium. Contact Dermatitis. 2009;60(4):229-30. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Esketamine Is Linked to Lower Levels of One Nutrient
Natural Medicines records Esketamine as a medicine that can lower these. This is not an interaction with Nasturtium — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Esketamine nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Nasturtium and Esketamine Together: Common Questions
Is it safe to take Nasturtium with Esketamine?
Does Esketamine interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Still Have a Question About Esketamine and Nasturtium?
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.