Drug & supplement interaction

Oak Moss + nilotinib

nilotinib brand name: Tasigna.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Oak Moss and nilotinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Oak Moss and nilotinib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between nilotinib and Oak Moss in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Oak Moss at all — not against nilotinib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Oak Moss safety at a glance

Oak Moss overall Use caution Oak moss is a recognized skin allergen and is not well studied as an oral supplement.
Pregnancy Possibly Unsafe When used orally. The constituent thujone shows evidence of uterine stimulant activity. Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally. The constituent thujone shows evidence of uterine stimulant activity. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining nilotinib and Oak Moss? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Oak Moss and nilotinib May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. 4 of them are worth acting on rather than waiting out — marked below.

  • Yellowing of the skin or eyes Worth acting on Additional detail

    Oak Moss

    “Orally, usnic acid, a constituent of oak moss, has been associated with reports of hepatotoxicity. From July to December 2000 there were at least seven cases of acute hepatotoxicity in patients taking LipoKinetix, a product containing usnic acid as sodium usniate.”

    Oak Moss · Natural Medicines adverse-effect record, reported in fatigue.

    6 sources cited
    1. 7091. Favreau JT, Ryu Ml, Braunstein G, et al. Severe hepatotoxicity associated with the dietary supplement LipoKinetix. Ann Intern Med 2002;136:590-5. PubMed
    2. 81595. Durazo, F. A., Lassman, C., Han, S. H., Saab, S., Lee, N. P., Kawano, M., Saggi, B., Gordon, S., Farmer, D. G., Yersiz, H., Goldstein, R. L., Ghobrial, M., and Busuttil, R. W. Fulminant liver failure due to usnic acid for weight loss. Am.J Gastroenterol. PubMed
    3. 81600. Neff, G. W., Reddy, K. R., Durazo, F. A., Meyer, D., Marrero, R., and Kaplowitz, N. Severe hepatotoxicity associated with the use of weight loss diet supplements containing ma huang or usnic acid. J Hepatol. 2004;41(6):1062-1064. PubMed
    4. 81607. Hsu, L. M., Huang, Y. S., Chang, F. Y., and Lee, S. D. 'Fat burner' herb, usnic Acid, induced acute hepatitis in a family. J Gastroenterol.Hepatol. 2005;20(7):1138-1139. PubMed
    5. 81612. Arneborn, P., Jansson, A., and Bottiger, Y. [Acute hepatitis in a woman after intake of slimming pills bought via Internet]. Lakartidningen 7-11-2005;102(28-29):2071-2072.
    6. 81619. Sanchez, W., Maple, J. T., Burgart, L. J., and Kamath, P. S. Severe hepatotoxicity associated with use of a dietary supplement containing usnic acid. Mayo Clin Proc 2006;81(4):541-544. PubMed

    nilotinib

    Listed in the ADVERSE REACTIONS section of the FDA label for nilotinib. Read the label on DailyMed ›

  • Kidney problems Worth acting on Additional detail

    Oak Moss

    “Orally, oak moss seems to be well tolerated when taken in small amounts, short-term. However, a high-quality assessment of safety has not been conducted. When oak moss is used long-term, in large amounts of tea, or as a hot alcoholic extract, it may be unsafe due to various constituents, including thujone and usnic acid.

    Most Common Adverse Effects:

    Topically: Oak moss may cause contact sensitivity and allergic react…”

    Oak Moss · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).

    nilotinib

    Listed in the ADVERSE REACTIONS section of the FDA label for nilotinib. Read the label on DailyMed ›

  • Liver problems Worth acting on Additional detail

    Oak Moss

    Recorded for Oak Moss in the same Natural Medicines adverse-effect record shown under Kidney problems above.

    nilotinib

    Listed in the ADVERSE REACTIONS section of the FDA label for nilotinib. Read the label on DailyMed ›

  • An allergic reaction Worth acting on Additional detail

    Oak Moss

    “Topically, use of oak moss may cause contact sensitivity and allergic reactions in people with lichen and moss allergy. In patch testing, very late reactions have occurred, some as late as 27 days after application. Usnic acid, a constituent of oak moss, also can cause allergic contact dermatitis with respiratory symptoms.”

    Oak Moss · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).

    6 sources cited
    1. 4023. Dahlquist I, Fregert S. Contact allergy to atranorin in lichens and perfumes. Contact Dermatitis 1980;6:111-9. PubMed
    2. 4033. Goncalo S. Contact sensitivity to lichens and compositae in Frullania dermatitis. Contact Dermatitis 1987;16:84-6. PubMed
    3. 4034. Goncalo S, Cabral F, Goncalo M. Contact sensitivity to oak moss. Contact Dermatitis 1988;19:355-7. PubMed
    4. 4039. Thune P, Solberg Y, McFadden N, et al. Perfume allergy due to oak moss and other lichens. Contact Dermatitis 1982;8:396-400. PubMed
    5. 108403. Schubert S, Schnuch A, Bauer A, et al. Very late reactions in the patch test with fragrance mix I and oak moss absolute (Evernia prunastri, INCI): Data of the Information Network of Departments of Dermatology (IVDK). Contact Dermatitis 2022;86(1):54-57.
    6. 11720. Ingolfsdottir K. Usnic acid. Phytochemistry 2002;61:729-36.

    nilotinib

    Listed in the ADVERSE REACTIONS section of the FDA label for nilotinib. Read the label on DailyMed ›

  • Weight loss / Stomach pain / Tiredness Additional detail

    Oak Moss

    Recorded for Oak Moss in the same Natural Medicines adverse-effect record shown under Yellowing of the skin or eyes above.

    nilotinib

    Listed in the ADVERSE REACTIONS section of the FDA label for nilotinib. Read the label on DailyMed ›

  • Anxiety or restlessness / Dizziness Additional detail

    Oak Moss

    “Orally, large amounts or long-term use of thujone-containing products, such as oak moss, may cause convulsions, restlessness, tremors, and vertigo (12).”

    Oak Moss · Natural Medicines adverse-effect record, reported in vertigo.

    1 source cited
    1. 12. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.

    nilotinib

    Listed in the ADVERSE REACTIONS section of the FDA label for nilotinib. Read the label on DailyMed ›

  • A skin rash Additional detail

    Oak Moss

    Recorded for Oak Moss in the same Natural Medicines adverse-effect record shown under Kidney problems above.

    nilotinib

    Listed in the ADVERSE REACTIONS section of the FDA label for nilotinib. Read the label on DailyMed ›

Showing the 10 most notable of 12 shared effects — ranked by how unusual each one is, not just whether both lists mention it.

Reported for Oak Moss but not commonly for nilotinib: seizures.

Effects for nilotinib come from the ADVERSE REACTIONS section of its FDA label; effects for Oak Moss come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Oak Moss in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally. The constituent thujone shows evidence of uterine stimulant activity.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With nilotinib

This page covers Oak Moss only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the nilotinib page lists 221 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Beer (major) and Cesium (major).

By severity: 11 major · 176 moderate · 34 minor.

From our pharmacist’s overview on the nilotinib page

“Nilotinib (Tasigna) is a targeted therapy for chronic myeloid leukemia, cleared by the liver enzyme CYP3A4 and known to affect heart rhythm, so its supplement list calls for genuine care. Eleven of the 221 ingredients here carry a major rating, and those belong at the top of your reading.”

Reviewed by 2 · Jul 18, 2026

Open the nilotinib interaction page

How much people look this up

Where Oak Moss and nilotinib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Oak Moss
Steady interest

#1,074 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication nilotinib
Top half

#1,353 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Oak Moss reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Oak Moss and nilotinib records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Oak Moss

What is Oak Moss?

Oak Moss
  • Perfume base note and scent fixative
  • Aromatherapy and fragrance
  • Traditional antimicrobial use
  • Soaps and cosmetics fragrance

Oak moss is a lichen that grows on oak and other trees and is best known as a perfume ingredient prized for its earthy, woody scent. There is very little human evidence to support taking it for any health condition, and it is a well-known skin allergen, so it is mainly used externally in fragrances rather than as a dietary supplement.

Evernia prunastri · Parmeliaceae · Whole lichen (thallus) and its extract/absolute · Essential oil, absolute, extract, fragrance ingredient; occasionally tinctures

An interaction check asks whether these two react with each other — it does not ask whether Oak Moss is a good idea for someone in your situation. Here is what our Oak Moss record says about it on its own.

Oak Moss: dosing

There is no established safe or effective oral dose for oak moss. It is not a standard dietary supplement, and reliable dosing information from human studies does not exist.If you come across an oak moss product, follow the directions on the label and do not exceed them. Given the lack of safety data, oral use is generally not recommended.

From our Oak Moss monograph — the full record covers uses, side effects and every documented interaction.

Read the full Oak Moss monograph & all interactions
Medication

About Nilotinib

What Is Nilotinib Used For?

Brand name: Tasigna

  • Nilotinib is used to treat certain types of chronic myeloid leukemia (CML; a type of cancer of the white blood cells) who have recently found to have this condition in adults and children 1 year of age and older. It is also used to treat certain types of CML in adults whose disease could not be treated successfully with imatinib (Gleevec) or adults who cannot take imatinib because of side effects. Nilotinib is also used to treat certain types of CML in children 1 year of age or older whose disease could not be treated successfully with other tyrosine kinase inhibitor therapies or who cannot take these medications because of side effects. Nilotinib is in a class of medications called kinase inhibitors. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

See full Nilotinib drug information
Keep checking

Other Drugs & Oak Moss

Browse every other medication we’ve checked against Oak Moss — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Oak Moss References

The 16 references that drive our Oak Moss monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Dahlquist I, Fregert S. Contact allergy to atranorin in lichens and perfumes. Contact Dermatitis 1980;6:111-9. PubMed
  4. Goncalo S. Contact sensitivity to lichens and compositae in Frullania dermatitis. Contact Dermatitis 1987;16:84-6. PubMed
  5. Goncalo S, Cabral F, Goncalo M. Contact sensitivity to oak moss. Contact Dermatitis 1988;19:355-7. PubMed
  6. Thune P, Solberg Y, McFadden N, et al. Perfume allergy due to oak moss and other lichens. Contact Dermatitis 1982;8:396-400. PubMed
  7. Favreau JT, Ryu Ml, Braunstein G, et al. Severe hepatotoxicity associated with the dietary supplement LipoKinetix. Ann Intern Med 2002;136:590-5. PubMed
  8. Ingolfsdottir K. Usnic acid. Phytochemistry 2002;61:729-36.
  9. Mitchell, J. C. Allergy to lichens. Allergic contact dermatitis from usnic acid produced by lichenized fungi. Arch Dermatol 1965;92(2):142-146.
  10. Durazo, F. A., Lassman, C., Han, S. H., Saab, S., Lee, N. P., Kawano, M., Saggi, B., Gordon, S., Farmer, D. G., Yersiz, H., Goldstein, R. L., Ghobrial, M., and Busuttil, R. W. Fulminant liver failure due to usnic acid for weight loss. Am.J Gastroenterol. PubMed
  11. Neff, G. W., Reddy, K. R., Durazo, F. A., Meyer, D., Marrero, R., and Kaplowitz, N. Severe hepatotoxicity associated with the use of weight loss diet supplements containing ma huang or usnic acid. J Hepatol. 2004;41(6):1062-1064. PubMed
  12. Hsu, L. M., Huang, Y. S., Chang, F. Y., and Lee, S. D. 'Fat burner' herb, usnic Acid, induced acute hepatitis in a family. J Gastroenterol.Hepatol. 2005;20(7):1138-1139. PubMed
  13. Arneborn, P., Jansson, A., and Bottiger, Y. [Acute hepatitis in a woman after intake of slimming pills bought via Internet]. Lakartidningen 7-11-2005;102(28-29):2071-2072.
  14. Sanchez, W., Maple, J. T., Burgart, L. J., and Kamath, P. S. Severe hepatotoxicity associated with use of a dietary supplement containing usnic acid. Mayo Clin Proc 2006;81(4):541-544. PubMed
  15. Rafanelli, S., Bacchilega, R., Stanganelli, I., and Rafanelli, A. Contact dermatitis from usnic acid in vaginal ovules. Contact Dermatitis 1995;33(4):271-272. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Oak Moss and nilotinib Together: Common Questions

Is it safe to take Oak Moss with nilotinib?
We do not list a known interaction between Oak Moss and nilotinib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Oak Moss and nilotinib have any of the same side effects?
Yes — our sources link each of them separately to 10 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does nilotinib interact with any supplements?
Yes. nilotinib has documented interactions with 221 supplements in our database — Oak Moss is not one of them. The nilotinib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About nilotinib and Oak Moss?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.