Drug & supplement interaction

Pangamic Acid + Vinblastine

Vinblastine brand name: Velban.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 27, 2026
The bottom line No known interaction

We found no known interaction between Pangamic Acid and Vinblastine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Pangamic Acid and Vinblastine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Vinblastine and Pangamic Acid in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Pangamic Acid at all — not against Vinblastine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Pangamic Acid safety at a glance

Pangamic Acid overall Avoid It has no proven benefit, no standard composition, and some forms have raised safety concerns.
Pregnancy Possibly Unsafe When used orally; avoid using because it is difficult to know what constituents are present. Dichloroacetate, present in some formulations, is mutagenic accordi... Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally; avoid using because it is difficult to know what constituents are present. Dichloroacetate, present in some formulations, is mutagenic accordi... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Vinblastine and Pangamic Acid? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Vinblastine’s Own FDA Label Lists

This is not an interaction — none of it involves Pangamic Acid. These are the most notable effects listed in the ADVERSE REACTIONS section of Vinblastine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Hearing loss Worth acting on
  • A bowel blockage Worth acting on
  • Bleeding in the gut Worth acting on
  • A heart attack Worth acting on
  • Seizures Worth acting on
  • Chest pain Worth acting on
  • Low mood Worth acting on
  • A low platelet count Worth acting on
  • Anemia Worth acting on
  • Raised blood pressure Worth acting on

Showing the 10 most notable of 24 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Vinblastine. Read the label on DailyMed › Pangamic Acid’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Pangamic Acid side to compare — that is a limit of the record, not a statement that Pangamic Acid has no side effects.

Special populations

Pangamic Acid in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally; avoid using because it is difficult to know what constituents are present. Dichloroacetate, present in some formulations, is mutagenic according to the Ames test.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Overlapping uses

What Vinblastine Is Prescribed For, and What Pangamic Acid Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Vinblastine is a prescription medicine with approved uses on its FDA label. Pangamic Acid is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Vinblastine is prescribed for: Vinblastine Sulfate Injection is used in the treatment of a range of cancers. Conditions that tend to respond well include generalized Hodgkin's disease, lymphocytic lymphoma, histiocytic lymphoma, advanced mycosis fungoides (a type of skin lymphoma), advanced testicular cancer, Kaposi's sarcoma, and Letterer-Siwe disease (a rare immune condition also called histiocytosis X). It may also be used for cancers that respond less reliably, such as choriocarcinoma resistant to other chemotherapy drugs, and breast cancer that has not responded to hormonal therapy. Vinblastine is often given as part of a combination chemotherapy regimen alongside other cancer medicines to improve response rates.

Pangamic Acid has been studied for:

  • Cancer studied, not established Pangamic Acid has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Pangamic Acid for cancer

    Although there has been interest in using oral pangamic acid for cancer, there is insufficient reliable information about the clinical effects of pangamic acid for this purpose.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Vinblastine on your own; if you are taking Pangamic Acid for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Vinblastine

This page covers Pangamic Acid only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Vinblastine page lists 161 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 119 moderate · 39 minor.

From our pharmacist’s overview on the Vinblastine page

“Vinblastine (Velban) is intravenous chemotherapy, most often for lymphomas and testicular cancer, and its safety margin is thin enough that I treat every supplement on this list as a real question, not a formality. Of the 161 ingredients on file, three rate major, and those three deserve attention first: grapefruit and St.”

Reviewed by 2 · Jul 18, 2026

Open the Vinblastine interaction page

One more smart check

Taking Pangamic Acid as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1 real supplement products containing Pangamic Acid, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Pangamic Acid. Even though Pangamic Acid itself has no known interaction with Vinblastine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Pangamic Acid and Vinblastine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Pangamic Acid
Steady interest

#1,068 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Vinblastine
Steady interest

#2,632 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Pangamic Acid reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Pangamic Acid and Vinblastine records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Pangamic Acid

What is Pangamic Acid?

  • Claimed athletic performance and endurance
  • General fatigue and energy
  • Heart and circulation support
  • Detoxification claims
  • Antioxidant claims

Pangamic acid, often marketed as 'vitamin B15,' is not a true vitamin and has no established health benefit. Its chemical makeup has never been consistent across products, some versions have raised safety concerns, and it is not approved as a supplement in the United States. We do not recommend using it.

Not a plant part; a synthetic or apricot-kernel-derived chemical compound · Tablets, capsules (often labeled 'B15' or 'vitamin B15')

An interaction check asks whether these two react with each other — it does not ask whether Pangamic Acid is a good idea for someone in your situation. Here is what our Pangamic Acid record says about it on its own.

Pangamic Acid: dosing

There is no established or recommended dose for pangamic acid, and no health authority endorses its use. In most cases, the best advice is to choose a different, well-studied option instead.

From our Pangamic Acid monograph — the full record covers uses, side effects and every documented interaction.

Read the full Pangamic Acid monograph & all interactions
Medication

About Vinblastine

What Is Vinblastine Used For?

Brand name: Velban

Vinblastine Sulfate Injection is used in the treatment of a range of cancers. Conditions that tend to respond well include generalized Hodgkin's disease, lymphocytic lymphoma, histiocytic lymphoma, advanced mycosis fungoides (a type of skin lymphoma), advanced testicular cancer, Kaposi's sarcoma, and Letterer-Siwe disease (a rare immune condition also called histiocytosis X).

It may also be used for cancers that respond less reliably, such as choriocarcinoma resistant to other chemotherapy drugs, and breast cancer that has not responded to hormonal therapy. Vinblastine is often given as part of a combination chemotherapy regimen alongside other cancer medicines to improve response rates.

See full Vinblastine drug information
Keep checking

Other Drugs & Pangamic Acid

Browse every other medication we’ve checked against Pangamic Acid — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Pangamic Acid against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Pangamic Acid list.

See the full Pangamic Acid interactions page
See every supplement checked against Vinblastine, ranked by severity
Evidence & sources

Pangamic Acid References

The 1 references that drive our Pangamic Acid monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Pangamic Acid and Vinblastine Together: Common Questions

Is it safe to take Pangamic Acid with Vinblastine?
We do not list a known interaction between Pangamic Acid and Vinblastine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Pangamic Acid and Vinblastine used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Pangamic Acid in each. That is a conversation for your prescriber, especially if Vinblastine is being adjusted to a target.
Does Vinblastine interact with any supplements?
Yes. Vinblastine has documented interactions with 161 supplements in our database — Pangamic Acid is not one of them. The Vinblastine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Pangamic Acid monograph Uses, safety profile, and every drug interaction in one place Vinblastine drug information The full plain-English guide to this medication Vinblastine supplement interactions Every supplement checked against Vinblastine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Vinblastine and Pangamic Acid?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.