Medication interaction hub

What Supplements Interact with Vinblastine?

Vinblastine brand name: Velban. Every interaction below applies to the brands too.

161 Interactions 3 Major 119 Moderate 39 Minor
Curated & coded by · Clinical Pharmacist · Updated September 27, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Vinblastine? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Vinblastine against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Vinblastine (Velban) is intravenous chemotherapy, most often for lymphomas and testicular cancer, and its safety margin is thin enough that I treat every supplement on this list as a real question, not a formality. Of the 161 ingredients on file, three rate major, and those three deserve attention first: grapefruit and St. John's wort change how the liver clears vinblastine through the CYP3A4 pathway, and activated charcoal can pull the drug out of circulation even though vinblastine is given by IV.

That liver pathway explains most of this page. Well over a hundred entries can nudge vinblastine levels up (more toxicity) or down (less cancer-fighting effect), a smaller group affects the pump that moves the drug out of cells, and about twenty add to sun sensitivity. Against a chemotherapy dose calculated to the milligram, even the 119 moderate and 39 minor entries earn a conversation with your oncology pharmacist.

— , Clinical Pharmacist · July 18, 2026

Major 3 Moderate 119 Minor 39 No known interaction 1,291

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Vinblastine: Top Interactions at a Glance

The Vinblastine supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 161 interacting ingredients — plus 1,291 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Vinblastine Combinations Today

The Vinblastine + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Minor Likelihood Possible Yerba Mate + Vinblastinei

Theoretically, yerba mate might increase the levels and clinical effects of CYP3A4 substrates.

Read the full interaction Minor Likelihood Possible Honey + Vinblastinei

Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.

Read the full interaction Minor Likelihood Possible Bael + Vinblastinei

Bael and its constituents marmelosin and marmesinin inhibited cytochrome P450 3A4 (CYP3A4) activity in vitro.

Read the full interaction Moderate Likelihood Possible Padang Cassia + Vinblastinei

In vitro research shows that a methanol extract of Padang cassia inhibits cytochrome P450 3A4 (CYP3A4) activity.

Read the full interaction Major Likelihood Likely Grapefruit + Vinblastinei

Grapefruit juice can increase levels of drugs metabolized by CYP3A4.

Read the full interaction Major Likelihood Probable Activated Charcoal + Vinblastinei

Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.

Read the full interaction
The complete list

Every Supplement Checked Against Vinblastine

All 1,452 ingredients in our database, ranked by severity — 161 with a Vinblastine interaction on file and 1,291 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Vinblastine?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Yerba Mate with Vinblastine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, yerba mate might increase the levels and clinical effects of CYP3A4 substrates.

Full Yerba Mate + Vinblastine answer

Can you take Honey with Vinblastine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.

Full Honey + Vinblastine answer

Can you take Bael with Vinblastine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Bael and its constituents marmelosin and marmesinin inhibited cytochrome P450 3A4 (CYP3A4) activity in vitro.

Full Bael + Vinblastine answer

Can you take Padang Cassia with Vinblastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro research shows that a methanol extract of Padang cassia inhibits cytochrome P450 3A4 (CYP3A4) activity.

Full Padang Cassia + Vinblastine answer

Can you take Fo-ti with Vinblastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, fo-ti might increase the levels and clinical effects of drugs metabolized by CYP3A4.

Full Fo-ti + Vinblastine answer

Can you take Garlic with Vinblastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.

Full Garlic + Vinblastine answer

Can you take German Chamomile with Vinblastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.

Full German Chamomile + Vinblastine answer

Can you take Ginger with Vinblastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Ginger might increase or decrease the levels of CYP3A4 substrates.

Full Ginger + Vinblastine answer

Can you take Ginkgo with Vinblastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, ginkgo might decrease levels of drugs metabolized by CYP3A4.

Full Ginkgo + Vinblastine answer

Can you take Goji with Vinblastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, goji berry might inhibit CYP3A4 and reduce metabolism of CYP3A4 substrates.

Full Goji + Vinblastine answer

Can you take Goldthread with Vinblastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. There's very preliminary evidence that berberine, a constituent of goldthread, might inhibit cytochrome P450 3A4 (CYP3A4) enzyme.

Full Goldthread + Vinblastine answer

Can you take Grape with Vinblastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.

Full Grape + Vinblastine answer

Can you take Green Tea with Vinblastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Green tea might increase the levels and adverse effects of P-glycoprotein (P-gp) substrates.

Full Green Tea + Vinblastine answer

Can you take Guar Gum with Vinblastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Guar gum might reduce the absorption of some oral drugs, potentially decreasing their effectiveness.

Full Guar Gum + Vinblastine answer

Can you take Gum Arabic with Vinblastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.

Full Gum Arabic + Vinblastine answer

Can you take Hesperidin with Vinblastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, hesperidin might inhibit P-glycoprotein-mediated drug efflux and potentially increase levels of drugs that are substrates of...

Full Hesperidin + Vinblastine answer

Can you take Higenamine with Vinblastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, higenamine might increase the levels and clinical effects drugs metabolized by CYP3A4.

Full Higenamine + Vinblastine answer

Can you take Horny Goat Weed with Vinblastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, horny goat weed might increase the effects and side effects of CYP3A4 substrates.

Full Horny Goat Weed + Vinblastine answer

Can you take Hu Zhang with Vinblastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.

Full Hu Zhang + Vinblastine answer

Can you take Indian Long Pepper with Vinblastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.

Full Indian Long Pepper + Vinblastine answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Vinblastine is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Vinblastine, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Vinblastine sits in 4 interaction categories. Open any one to see what the group means:

Cytochrome P450 3A4 (Cyp3A4) Substrates 121 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

121 of the supplement ingredients on this page reach Vinblastine through this category.

P-Glycoprotein Substrates 37 ingredients

A drug-transport group: these medications are moved in and out of cells by the P-glycoprotein pump. Supplements that affect the pump can change how much of the drug is absorbed or kept in the body.

37 of the supplement ingredients on this page reach Vinblastine through this category.

Photosensitizing Drugs 20 ingredients

Medications that make skin more sun-sensitive. Supplements with the same property can compound it.

20 of the supplement ingredients on this page reach Vinblastine through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Vinblastine through this category.

About Vinblastine

Vinblastine is a chemotherapy medicine used intravenously to treat several cancers, including Hodgkin's disease, certain lymphomas, testicular cancer, Kaposi's sarcoma, and other malignancies.

Generic name: Vinblastine  ·  Brand name: Velban.

See the full Vinblastine drug information
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Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Vinblastine.

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Pharmacist Counseling Corner

Vinblastine & Supplements: Common Questions

What supplements interact with Vinblastine?
More than you might expect — 161 in total, though they are far from equal: 3 are rated major, 119 moderate, and 39 minor. The ranked list on this page puts the ones that genuinely matter first, and every entry opens a full report on that exact pair. The highest-ranked right now: Grapefruit, Activated Charcoal, St. John's Wort.
Which Vinblastine supplement interactions are the most serious?
Focus on the major group: Grapefruit, Activated Charcoal and St. John's Wort. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Vinblastine?
Usually yes — most people on Vinblastine can take most supplements. The catch is the exceptions, and they aren't always the exotic ones (St. John's Wort trips up more prescriptions than almost anything sold next to it). Look up each ingredient you actually take in the list above, and treat "no known interaction" as a green-ish light, not a guarantee. Try the label scanner or the interaction checker.
Do brands like Velban have the same supplement interactions as Vinblastine?
Yes — Velban all contain Vinblastine, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Vinblastine and my other medications?
This page covers Vinblastine against supplements and herbal ingredients. Checking Vinblastine against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Vinblastine drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 27, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.