Drug & supplement interaction

Patchouli Oil + Crizotinib

Crizotinib brand name: Xalkori.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Patchouli Oil and Crizotinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Patchouli Oil and Crizotinib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Crizotinib and Patchouli Oil in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Patchouli Oil at all — not against Crizotinib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Patchouli Oil safety at a glance

Patchouli Oil overall Use caution Generally considered safe for topical and aromatherapy use when diluted, but can irritate skin and should not be swallowed.
Pregnancy Avoid Safety is not established, so avoid use during pregnancy unless cleared by your doctor.
Breastfeeding Avoid Not enough safety information exists, so it is best avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Crizotinib and Patchouli Oil? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Crizotinib’s Own FDA Label Lists

This is not an interaction — none of it involves Patchouli Oil. These are the most notable effects listed in the ADVERSE REACTIONS section of Crizotinib’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Muscle weakness Worth acting on
  • Trouble swallowing Worth acting on
  • Unsteadiness Worth acting on
  • A slow heartbeat Worth acting on
  • Blood clots Worth acting on
  • Fainting Worth acting on
  • An irregular heartbeat Worth acting on
  • A low platelet count Worth acting on
  • Shortness of breath Worth acting on
  • A low white blood cell count Worth acting on

Showing the 10 most notable of 36 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Crizotinib. Read the label on DailyMed › Where a percentage is shown, it is the share of 12,638 voluntary FDA FAERS reports for Crizotinib that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Patchouli Oil’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Patchouli Oil side to compare — that is a limit of the record, not a statement that Patchouli Oil has no side effects.

Everything else you take

See Every Supplement That Interacts With Crizotinib

This page covers Patchouli Oil only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Crizotinib page lists 157 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).

By severity: 8 major · 112 moderate · 37 minor.

From our pharmacist’s overview on the Crizotinib page

“Grapefruit tops my worry list for crizotinib (Xalkori), a targeted pill for ALK-positive lung cancer. It blocks the enzyme (CYP3A4) that clears crizotinib, letting levels climb and side effects with them, and it is one of eight major-rated entries among the 157 supplements and herbs on file for this drug.”

Reviewed by 2 · Jul 18, 2026

Open the Crizotinib interaction page

How much people look this up

Where Patchouli Oil and Crizotinib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Patchouli Oil
Steady interest

#1,072 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Crizotinib
Steady interest

#2,222 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Patchouli Oil reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Patchouli Oil and Crizotinib records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Patchouli Oil

What is Patchouli Oil?

  • Aromatherapy and relaxation
  • Skin care
  • Insect repellent
  • Fragrance and perfume
  • Antimicrobial use
  • Mood support

Patchouli oil is an essential oil pressed from the leaves of the patchouli plant, used mainly for its strong, earthy scent in aromatherapy, skin products, and perfumes. Most claimed health benefits come from laboratory studies rather than solid human trials, so its real-world value remains unproven. Like all essential oils, it should be diluted before skin use and never swallowed unless directed by a qualified professional.

Pogostemon cablin · Lamiaceae · Leaves (dried and steam-distilled essential oil) · Essential oil, diluted oil blends, soaps, lotions, perfumes, incense

An interaction check asks whether these two react with each other — it does not ask whether Patchouli Oil is a good idea for someone in your situation. Here is what our Patchouli Oil record says about it on its own.

Patchouli Oil: dosing

There is no established standard dose for patchouli oil, and it is not meant to be taken by mouth. For topical use, it is typically diluted to a small percentage in a carrier oil before being applied to the skin.For aromatherapy, a few drops may be added to a diffuser according to the product directions.

From our Patchouli Oil monograph — the full record covers uses, side effects and every documented interaction.

Read the full Patchouli Oil monograph & all interactions
Medication

About Crizotinib

What Is Crizotinib Used For?

Brand name: Xalkori

Xalkori (crizotinib) is used to treat adult patients with metastatic non-small cell lung cancer (NSCLC) whose tumors test positive for the ALK or ROS1 gene abnormality, as confirmed by an FDA-approved test.

Xalkori is also used to treat pediatric patients aged 1 year and older and young adults with relapsed or refractory systemic ALK-positive anaplastic large cell lymphoma (ALCL). Additionally, it treats adult and pediatric patients aged 1 year and older with unresectable, recurrent, or refractory ALK-positive inflammatory myofibroblastic tumor (IMT). Note: Xalkori's safety and effectiveness in older adults with relapsed or refractory ALK-positive ALCL have not been established.

Most-Reported Side Effects for Crizotinib

From FAERS, the FDA’s public side-effect reporting system (12,638 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Disease progression 1,216 reports
Nausea 1,118 reports
Neoplasm progression 1,112 reports
Diarrhea 846 reports
Vomiting 795 reports
See full Crizotinib drug information
Keep checking

Other Drugs & Patchouli Oil

Browse every other medication we’ve checked against Patchouli Oil — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Patchouli Oil References

The 2 references that drive our Patchouli Oil monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Das NG, Dhiman S, Talukdar PK, Rabha B, Goswami D, Veer V. Synergistic mosquito-repellent activity of Curcuma longa, Pogostemon heyneanus and Zanthoxylum limonella essential oils. J Infect Public Health. 2015 Jul-Aug;8(4):323-8. PubMed
  2. Shin YK, Lee SY, Lee JM, Kang P, Seol GH. Effects of short-term inhalation of patchouli oil on professional quality of life and stress levels in emergency nurses: A randomized controlled trial. J Altern Complement Med. 2020 Nov;26(11):1032-1038. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Patchouli Oil and Crizotinib Together: Common Questions

Is it safe to take Patchouli Oil with Crizotinib?
We do not list a known interaction between Patchouli Oil and Crizotinib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Crizotinib interact with any supplements?
Yes. Crizotinib has documented interactions with 157 supplements in our database — Patchouli Oil is not one of them. The Crizotinib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Crizotinib and Patchouli Oil?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.