Drug & supplement interaction

Quince + Nifurtimox

Nifurtimox brand name: Lampit.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Quince and Nifurtimox in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Nifurtimox states a food rule worth keeping to.

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Interaction report

Quince and Nifurtimox

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Nifurtimox and Quince in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Quince at all — not against Nifurtimox, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Quince safety at a glance

Quince overall Use caution Quince as a food is generally well tolerated, but concentrated supplements are not well studied.
Pregnancy Use caution Quince as food is likely fine, but concentrated extracts or seed products lack safety data, so use caution.
Breastfeeding Use caution There is not enough reliable information on quince supplements during breastfeeding, so caution is advised.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Nifurtimox and Quince? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Nifurtimox’s Own FDA Label Lists

This is not an interaction — none of it involves Quince. These are the most notable effects listed in the ADVERSE REACTIONS section of Nifurtimox’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 2 of them are worth acting on rather than waiting out — marked below.

  • A higher chance of infection Worth acting on
  • An allergic reaction Worth acting on
  • Weight loss
  • Reduced appetite
  • Fever
  • Stomach pain
  • A skin rash
  • Vomiting
  • Headache
  • Nausea

From the ADVERSE REACTIONS section of the FDA label for Nifurtimox. Read the label on DailyMed › Quince’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Quince side to compare — that is a limit of the record, not a statement that Quince has no side effects.

How to take them

Some Nifurtimox Products Have a Food Rule — Quince Should Not Break It

At least one FDA label for a product containing Nifurtimox says to take it with food. If you take Quince on an empty stomach out of habit, keep them separate — and take Nifurtimox with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Nifurtimox products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

LAMPIT tablets must be taken with food ( 2.1 ) Dosage of LAMPIT in Pediatric Patients (birth a to less than 18 years of age) (2.2) Body Weight Group Total Daily Dose of nifurtimox (mg/kg) 41 kg or greater 8 to 10 Less than 41 kg 10 to 20 a Term newborn with body weight greater than or equal to 2.5 kg • Administer LAMPIT tablets orally, three times daily with food for

From the Dosage and Administration section of the FDA label we read for Nifurtimox — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Nifurtimox

This page covers Quince only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Nifurtimox page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Nifurtimox page

“Nifurtimox (Lampit) treats Chagas disease over a course lasting weeks, and it only works if enough of each dose is absorbed, which is why the 17 supplements flagged here call for real vigilance. Every single one can change how oral medications are taken up from the gut.”

Reviewed by 2 · Jul 18, 2026

Open the Nifurtimox interaction page

One more smart check

Taking Quince as Part of a Dietary Supplement Product? Check It for Interactions

We hold 25 real supplement products containing Quince, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Quince. Even though Quince itself has no known interaction with Nifurtimox, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Quince and Nifurtimox Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Quince
Steady interest

#977 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Nifurtimox
Steady interest

#2,306 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources.
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Quince and Nifurtimox records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Quince

What is Quince?

  • Digestive upset and diarrhea
  • Acid reflux and heartburn
  • Sore throat and cough
  • Skin soothing and wound care
  • Nausea

Quince is a tart, apple-like fruit traditionally used for digestive complaints, reflux, and soothing the throat and skin. Early research is interesting but limited, so quince should not replace proven treatments. Enjoying cooked quince in food is generally fine, but talk to a pharmacist or doctor before using concentrated supplements.

Cydonia oblonga · Rosaceae · Fruit, seeds, and leaves · Fresh fruit, jam or jelly, syrup, tea, dried seeds, capsules, extracts

An interaction check asks whether these two react with each other — it does not ask whether Quince is a good idea for someone in your situation. Here is what our Quince record says about it on its own.

Quince: dosing

There is no standardized or proven dose for quince supplements. The right amount depends on the product, the part of the plant used, and how it is prepared, which varies a lot between brands.If you choose to use a quince product, follow the directions on the label and do not exceed the suggested amount. Avoid eating raw or crushed seeds.

From our Quince monograph — the full record covers uses, side effects and every documented interaction.

Read the full Quince monograph & all interactions
Medication

About Nifurtimox

What Is Nifurtimox Used For?

Brand name: Lampit

Lampit (nifurtimox) is approved to treat Chagas disease (American Trypanosomiasis), a parasitic infection caused by Trypanosoma cruzi. Lampit is approved specifically for pediatric patients from birth to under 18 years of age who weigh at least 2.5 kg (about 5.5 lbs).

Chagas disease can affect both the blood and tissues. Nifurtimox works against multiple forms of the parasite, including those inside and outside of cells.

See full Nifurtimox drug information
Keep checking

Other Drugs & Quince

Browse every other medication we’ve checked against Quince — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Sources

Sources & How We Checked

We checked Quince against Nifurtimox in the Natural Medicines interaction database and found no documented interaction on file. The medication overview comes from MedlinePlus, and supplement label details from the NIH Dietary Supplement Label Database.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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Pharmacist Counseling Corner

Taking Quince and Nifurtimox Together: Common Questions

Is it safe to take Quince with Nifurtimox?
We do not list a known interaction between Quince and Nifurtimox. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Quince and Nifurtimox at the same time of day?
At least one FDA label for a product containing Nifurtimox says to take it with food. If you take Quince on an empty stomach out of habit, keep them separate and take Nifurtimox with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Nifurtimox products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does Nifurtimox interact with any supplements?
Yes. Nifurtimox has documented interactions with 17 supplements in our database — Quince is not one of them. The Nifurtimox interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Nifurtimox and Quince?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.