Drug & supplement interaction

Quince + Quetiapine

Quetiapine brand names: Seroquel, Dopaquel.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Quince and Quetiapine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Quetiapine states a food rule worth keeping to.

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Interaction report

Quince and Quetiapine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Quetiapine and Quince in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Quince at all — not against Quetiapine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Quince safety at a glance

Quince overall Use caution Quince as a food is generally well tolerated, but concentrated supplements are not well studied.
Pregnancy Use caution Quince as food is likely fine, but concentrated extracts or seed products lack safety data, so use caution.
Breastfeeding Use caution There is not enough reliable information on quince supplements during breastfeeding, so caution is advised.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Quetiapine and Quince? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Quetiapine’s Own FDA Label Lists

This is not an interaction — none of it involves Quince. These are the most notable effects listed in the ADVERSE REACTIONS section of Quetiapine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Mania or an unusually elevated mood Worth acting on
  • A change in thyroid levels Worth acting on
  • Thoughts of self-harm Worth acting on
  • A bowel blockage Worth acting on
  • Severe muscle breakdown Worth acting on
  • Memory problems Worth acting on
  • High blood sugar Worth acting on mentioned in 4.4% of FDA reports for Quetiapine
  • Trouble swallowing Worth acting on
  • Trouble passing urine Worth acting on
  • Low sodium Worth acting on

Showing the 10 most notable of 63 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Quetiapine. Read the label on DailyMed › Where a percentage is shown, it is the share of 188,604 voluntary FDA FAERS reports for Quetiapine that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Quince’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Quince side to compare — that is a limit of the record, not a statement that Quince has no side effects.

How to take them

Some Quetiapine Products Have a Food Rule — Quince Should Not Break It

At least one FDA label for a product containing Quetiapine says to take it on an empty stomach. Most supplements — Quince included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Quetiapine on its own and move Quince to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Quetiapine products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

It is recommended that SEROQUEL XR be taken without food or with a light meal (approximately 300 calories) [see Clinical Pharmacology (12.3) ].

From the Dosage and Administration section of the FDA label we read for Quetiapine — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

From our Q&A

Questions About Quince or Quetiapine

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Quince or Quetiapine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Quetiapine

This page covers Quince only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Quetiapine page lists 199 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).

By severity: 11 major · 147 moderate · 41 minor.

From our pharmacist’s overview on the Quetiapine page

“Quetiapine (Seroquel) treats schizophrenia and bipolar disorder, illnesses where an unplanned swing in the drug's blood level has real consequences, and that is why these 199 supplement interactions deserve a careful read rather than a shrug. Most of the risk runs through CYP3A4, the liver enzyme that clears quetiapine: grapefruit bloc…”

Reviewed by 2 · Jul 18, 2026

Open the Quetiapine interaction page

One more smart check

Taking Quince as Part of a Dietary Supplement Product? Check It for Interactions

We hold 25 real supplement products containing Quince, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Quince. Even though Quince itself has no known interaction with Quetiapine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Quince and Quetiapine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Quince
Top half

#573 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Quetiapine
Top 5%

#46 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources.
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Quince and Quetiapine records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Quince

What is Quince?

  • Digestive upset and diarrhea
  • Acid reflux and heartburn
  • Sore throat and cough
  • Skin soothing and wound care
  • Nausea

Quince is a tart, apple-like fruit traditionally used for digestive complaints, reflux, and soothing the throat and skin. Early research is interesting but limited, so quince should not replace proven treatments. Enjoying cooked quince in food is generally fine, but talk to a pharmacist or doctor before using concentrated supplements.

Cydonia oblonga · Rosaceae · Fruit, seeds, and leaves · Fresh fruit, jam or jelly, syrup, tea, dried seeds, capsules, extracts

An interaction check asks whether these two react with each other — it does not ask whether Quince is a good idea for someone in your situation. Here is what our Quince record says about it on its own.

Quince: dosing

There is no standardized or proven dose for quince supplements. The right amount depends on the product, the part of the plant used, and how it is prepared, which varies a lot between brands.If you choose to use a quince product, follow the directions on the label and do not exceed the suggested amount. Avoid eating raw or crushed seeds.

From our Quince monograph — the full record covers uses, side effects and every documented interaction.

Read the full Quince monograph & all interactions
Medication

About Quetiapine

What Is Quetiapine Used For?

Brand names: Seroquel, Dopaquel

Quetiapine treats schizophrenia and bipolar disorder in adults and certain age groups of children and adolescents. For bipolar disorder, it is approved for manic episodes (both as a stand-alone treatment and alongside lithium or divalproex) and for depressive episodes.

The extended-release form of quetiapine is also approved as add-on therapy for major depressive disorder (MDD) in adults who are already taking an antidepressant. The regular tablet form is not approved for this use.

See full Quetiapine drug information
Keep checking

Other Drugs & Quince

Browse every other medication we’ve checked against Quince — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Quince against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Quince list.

See the full Quince interactions page
See every supplement checked against Quetiapine, ranked by severity
Sources

Sources & How We Checked

We checked Quince against Quetiapine in the Natural Medicines interaction database and found no documented interaction on file. The medication overview comes from MedlinePlus, and supplement label details from the NIH Dietary Supplement Label Database.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Quince monograph › Uses, safety, and every drug interaction in one place Quetiapine supplement interactions › Every supplement checked against Quetiapine, ranked by severity Quetiapine drug information › The full plain-English guide to this medication Supplement interaction checker › Check any supplement or product against your medications Browse medications A–Z › Every drug we've checked against herbs & supplements Ask a pharmacist › Free, personal answer from our licensed team
Pharmacist Counseling Corner

Taking Quince and Quetiapine Together: Common Questions

Is it safe to take Quince with Quetiapine?
We do not list a known interaction between Quince and Quetiapine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Quince and Quetiapine at the same time of day?
At least one FDA label for a product containing Quetiapine says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Quetiapine on its own and move Quince to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
Does Quetiapine interact with any supplements?
Yes. Quetiapine has documented interactions with 199 supplements in our database — Quince is not one of them. The Quetiapine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Quetiapine and Quince?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.