Drug & supplement interaction

Rolfing + Nintedanib Esylate

Nintedanib Esylate brand name: Ofev.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Rolfing and Nintedanib Esylate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Rolfing and Nintedanib Esylate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Nintedanib Esylate and Rolfing in our sources. This does not guarantee that the combination is completely free of risk — research on Rolfing alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Rolfing at all — not against Nintedanib Esylate, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Rolfing is a treatment rather than something you take. Tell whoever provides it which medicines you use, and ask your prescriber whether it is appropriate for your health and treatment. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Rolfing safety at a glance

Rolfing overall Use caution Generally considered low-risk when done by a trained practitioner, but the deep pressure can cause soreness and may not be appropriate for everyone.
Pregnancy Use caution Discuss with your obstetrician first; deep tissue work during pregnancy should only be done by practitioners experienced with pregnancy.
Breastfeeding Use caution No known direct effect on breast milk, but check with your healthcare provider before deep bodywork.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Nintedanib Esylate and Rolfing? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Nintedanib Esylate’s Own FDA Label Lists

This is not an interaction — none of it involves Rolfing. These are the most notable effects listed in the ADVERSE REACTIONS section of Nintedanib Esylate’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you have Rolfing and take the medicine. 9 of them are worth acting on rather than waiting out — marked below.

  • A change in thyroid levels Worth acting on
  • A heart attack Worth acting on
  • Pancreatitis Worth acting on
  • A low platelet count Worth acting on
  • Kidney problems Worth acting on
  • Raised blood pressure Worth acting on
  • Liver problems Worth acting on
  • Bleeding or bruising Worth acting on
  • A higher chance of infection Worth acting on
  • Weight loss mentioned in 9.7% of FDA reports for Nintedanib Esylate

Showing the 10 most notable of 24 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Nintedanib Esylate. Read the label on DailyMed › Where a percentage is shown, it is the share of 31,339 voluntary FDA FAERS reports for Nintedanib Esylate that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Rolfing’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Rolfing side to compare — that is a limit of the record, not a statement that Rolfing has no side effects.

Everything else you take

See Every Supplement That Interacts With Nintedanib Esylate

This page covers Rolfing only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Nintedanib Esylate page lists 285 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Danshen (major), Grapefruit (major), Piracetam (major) and St. John's Wort (major).

By severity: 5 major · 240 moderate · 40 minor.

From our pharmacist’s overview on the Nintedanib Esylate page

“You take Ofev (nintedanib) to slow lung scarring, and this page deserves a careful read before any supplement joins it. Of the 285 ingredients here, the biggest cluster, over 200, can add to bleeding risk, a real concern since nintedanib itself can make you bleed more easily.”

Reviewed by 2 · Jul 18, 2026

Open the Nintedanib Esylate interaction page

How much people look this up

Where Rolfing and Nintedanib Esylate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Rolfing
Steady interest

#914 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Nintedanib Esylate
Top half

#1,089 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Rolfing reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Rolfing and Nintedanib Esylate records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Treatment approach

About Rolfing

What is Rolfing?

  • Chronic back and neck pain
  • Postural alignment
  • Muscle tension and tightness
  • Improved flexibility and movement
  • Stress and body awareness

Rolfing is a form of hands-on bodywork (deep tissue manipulation of the connective tissue, or fascia), not an herb or dietary supplement that you swallow. Some people find it helps with posture, tension, and chronic pain, but high-quality scientific evidence is limited. If you have a health condition, talk with your doctor or pharmacist before starting Rolfing.

Not applicable — Rolfing is a hands-on bodywork therapy, not a plant or supplement · Hands-on sessions delivered by a certified Rolfer, often as a series of structured appointments

An interaction check asks whether these two react with each other — it does not ask whether Rolfing is a good idea for someone in your situation. Here is what our Rolfing record says about it on its own.

Rolfing: dosing

Because Rolfing is a hands-on therapy and not a supplement, there is no milligram dose or pill to take. It is delivered as in-person sessions by a trained, certified practitioner.Rolfing is often offered as a series of sessions (commonly described as a "Ten Series"), each lasting roughly an hour, but the number and frequency vary by practitioner and your needs.

From our Rolfing monograph — the full record covers uses, side effects and every documented interaction.

Read the full Rolfing monograph & all interactions
Medication

About Nintedanib

What Is Nintedanib Used For?

Brand name: Ofev

Nintedanib treats certain scarring lung diseases in adults. All the supported products are indicated for idiopathic pulmonary fibrosis (IPF) and for chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype (scarring lung disease that keeps getting worse).

Ofev, nintedanib capsules (100 mg and 150 mg) and one other nintedanib capsule product are also indicated to slow the decline in lung function in systemic sclerosis-associated interstitial lung disease (SSc-ILD). The nintedanib esylate capsule label lists only IPF and progressive chronic fibrosing ILDs.

See full Nintedanib drug information
Keep checking

Other Drugs & Rolfing

Browse every other medication we’ve checked against Rolfing — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Rolfing References

The 4 references that drive our Rolfing monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Perry J, Jones MH, Thomas L. Functional evaluation of Rolfing in cerebral palsy. Dev Med Child Neurol 1981;23:717-29. PubMed
  2. Weinberg RS, Hunt VV. Effects of structural integration on state-trait anxiety. J Clin Psychol 1979;35(2):319-22. PubMed
  3. Talty CM, DeMasi I, Deutsch JE. Structural integration applied to patients with chronic fatigue syndrome: a retrospective chart review. Journal of Orthopaedic & Sports Physical Therapy 1998;27(1):83.
  4. Brandl A, Bartsch K, James H, Miller ME, Schleip R. Influence of Rolfing structural integration on active range of motion: A retrospective cohort study. J Clin Med. 2022 Oct 5;11(19):5878. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Having Rolfing While Taking Nintedanib Esylate: Common Questions

Is it safe to have Rolfing while taking Nintedanib Esylate?
We do not list a known interaction between Rolfing and Nintedanib Esylate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Nintedanib Esylate interact with any supplements?
Yes. Nintedanib Esylate has documented interactions with 285 supplements in our database — Rolfing is not one of them. The Nintedanib Esylate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Nintedanib Esylate and Rolfing?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.