Drug & supplement interaction

Rolfing + Phenelzine Sulfate

Phenelzine Sulfate brand name: Nardil.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Rolfing and Phenelzine Sulfate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Rolfing and Phenelzine Sulfate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Phenelzine Sulfate and Rolfing in our sources. This does not guarantee that the combination is completely free of risk — research on Rolfing alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Rolfing at all — not against Phenelzine Sulfate, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Rolfing is a treatment rather than something you take. Tell whoever provides it which medicines you use, and ask your prescriber whether it is appropriate for your health and treatment. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Rolfing safety at a glance

Rolfing overall Use caution Generally considered low-risk when done by a trained practitioner, but the deep pressure can cause soreness and may not be appropriate for everyone.
Pregnancy Use caution Discuss with your obstetrician first; deep tissue work during pregnancy should only be done by practitioners experienced with pregnancy.
Breastfeeding Use caution No known direct effect on breast milk, but check with your healthcare provider before deep bodywork.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Phenelzine Sulfate and Rolfing? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Phenelzine Sulfate’s Own FDA Label Lists

This is not an interaction — none of it involves Rolfing. These are the most notable effects listed in the ADVERSE REACTIONS section of Phenelzine Sulfate’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you have Rolfing and take the medicine. 9 of them are worth acting on rather than waiting out — marked below.

  • Dependence or withdrawal symptoms Worth acting on
  • Trouble passing urine Worth acting on
  • Unsteadiness Worth acting on
  • Hallucinations Worth acting on
  • Yellowing of the skin or eyes Worth acting on
  • Confusion Worth acting on
  • Seizures Worth acting on
  • Low mood Worth acting on
  • A low white blood cell count Worth acting on
  • Vivid dreams or nightmares

Showing the 10 most notable of 31 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Phenelzine Sulfate. Read the label on DailyMed › Rolfing’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Rolfing side to compare — that is a limit of the record, not a statement that Rolfing has no side effects.

Overlapping uses

What Phenelzine Sulfate Is Prescribed For, and What Rolfing Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Phenelzine Sulfate is a prescription medicine with approved uses on its FDA label. Rolfing is a treatment: what follows is what researchers have looked at it for, and how strong that evidence is.

Phenelzine Sulfate is prescribed for: Phenelzine treats depression in people described as “atypical,” “nonendogenous,” or “neurotic.” These patients often have a mix of anxiety and depression, along with phobic or hypochondriacal features (intense fears or excessive worry about health). It is rarely the first antidepressant tried. It is more suitable for people who did not respond to the drugs more commonly used. Evidence is less conclusive for severe depression with endogenous features.

Read the rest of what Phenelzine Sulfate is prescribed for

These uses apply to Phenelzine Sulfate tablets and Nardil tablets.

Rolfing has been studied for:

  • Anxiety studied, not established Rolfing has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Rolfing for anxiety

    Preliminary clinical research shows that Rolfing might decrease anxiety in college students when used for one-hour, twice weekly for five weeks. The effect of Rolfing in patients with diagnosed anxiety disorders is unknown.

    1 source cited
    1. 88735. Weinberg RS, Hunt VV. Effects of structural integration on state-trait anxiety. J Clin Psychol 1979;35(2):319-22. PubMed

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Phenelzine Sulfate on your own; if you are taking Rolfing for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Phenelzine Sulfate

This page covers Rolfing only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Phenelzine Sulfate page lists 144 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Bitter Orange (major) and Brewer's Yeast (major).

By severity: 18 major · 111 moderate · 15 minor.

From our pharmacist’s overview on the Phenelzine Sulfate page

“Few medications demand as much dietary and supplement care as phenelzine sulfate (Nardil), an older MAOI antidepressant, and this list backs that up, with 18 of its 144 recorded interactions rated major. The two dominant themes are sedation and blood pressure.”

Reviewed by 2 · Jul 18, 2026

Open the Phenelzine Sulfate interaction page

How much people look this up

Where Rolfing and Phenelzine Sulfate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Rolfing
Steady interest

#1,094 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Phenelzine Sulfate
Top 25%

#534 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Rolfing reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Rolfing and Phenelzine Sulfate records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Treatment approach

About Rolfing

What is Rolfing?

  • Chronic back and neck pain
  • Postural alignment
  • Muscle tension and tightness
  • Improved flexibility and movement
  • Stress and body awareness

Rolfing is a form of hands-on bodywork (deep tissue manipulation of the connective tissue, or fascia), not an herb or dietary supplement that you swallow. Some people find it helps with posture, tension, and chronic pain, but high-quality scientific evidence is limited. If you have a health condition, talk with your doctor or pharmacist before starting Rolfing.

Not applicable — Rolfing is a hands-on bodywork therapy, not a plant or supplement · Hands-on sessions delivered by a certified Rolfer, often as a series of structured appointments

An interaction check asks whether these two react with each other — it does not ask whether Rolfing is a good idea for someone in your situation. Here is what our Rolfing record says about it on its own.

Rolfing: dosing

Because Rolfing is a hands-on therapy and not a supplement, there is no milligram dose or pill to take. It is delivered as in-person sessions by a trained, certified practitioner.Rolfing is often offered as a series of sessions (commonly described as a "Ten Series"), each lasting roughly an hour, but the number and frequency vary by practitioner and your needs.

From our Rolfing monograph — the full record covers uses, side effects and every documented interaction.

Read the full Rolfing monograph & all interactions
Medication

About Phenelzine

What Is Phenelzine Used For?

Brand name: Nardil

Phenelzine treats depression in people described as “atypical,” “nonendogenous,” or “neurotic.” These patients often have a mix of anxiety and depression, along with phobic or hypochondriacal features (intense fears or excessive worry about health).

It is rarely the first antidepressant tried. It is more suitable for people who did not respond to the drugs more commonly used. Evidence is less conclusive for severe depression with endogenous features. These uses apply to Phenelzine Sulfate tablets and Nardil tablets.

Most-Reported Side Effects for Phenelzine Sulfate

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Depression 187 reports
Headache 138 reports
Anxiety 129 reports
Weight increased 122 reports
Insomnia 104 reports
See full Phenelzine drug information
Keep checking

Other Drugs & Rolfing

Browse every other medication we’ve checked against Rolfing — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Rolfing References

The 4 references that drive our Rolfing monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Perry J, Jones MH, Thomas L. Functional evaluation of Rolfing in cerebral palsy. Dev Med Child Neurol 1981;23:717-29. PubMed
  2. Weinberg RS, Hunt VV. Effects of structural integration on state-trait anxiety. J Clin Psychol 1979;35(2):319-22. PubMed
  3. Talty CM, DeMasi I, Deutsch JE. Structural integration applied to patients with chronic fatigue syndrome: a retrospective chart review. Journal of Orthopaedic & Sports Physical Therapy 1998;27(1):83.
  4. Brandl A, Bartsch K, James H, Miller ME, Schleip R. Influence of Rolfing structural integration on active range of motion: A retrospective cohort study. J Clin Med. 2022 Oct 5;11(19):5878. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Having Rolfing While Taking Phenelzine Sulfate: Common Questions

Is it safe to have Rolfing while taking Phenelzine Sulfate?
We do not list a known interaction between Rolfing and Phenelzine Sulfate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Rolfing and Phenelzine Sulfate used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Rolfing in each. That is a conversation for your prescriber, especially if Phenelzine Sulfate is being adjusted to a target.
Does Phenelzine Sulfate interact with any supplements?
Yes. Phenelzine Sulfate has documented interactions with 144 supplements in our database — Rolfing is not one of them. The Phenelzine Sulfate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Phenelzine Sulfate and Rolfing?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.