Drug & supplement interaction

Rose Geranium Oil + Naloxegol

Naloxegol brand name: Movantik.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Rose Geranium Oil and Naloxegol in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Naloxegol states a food rule worth keeping to.

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Interaction report

Rose Geranium Oil and Naloxegol

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Naloxegol and Rose Geranium Oil in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Rose Geranium Oil at all — not against Naloxegol, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Rose Geranium Oil safety at a glance

Rose Geranium Oil overall Use caution Generally considered safe for diluted topical or aromatherapy use, but it can irritate skin and should not be swallowed.
Pregnancy Avoid Safety is not well studied, so it is best to avoid medicinal use during pregnancy.
Breastfeeding Avoid There is not enough reliable information, so avoid medicinal use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Naloxegol and Rose Geranium Oil? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Rose Geranium Oil Itself Has Been Linked To

This is not an interaction — nothing below involves Naloxegol. It is the side-effect record for Rose Geranium Oil on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Rose Geranium Oil, this list is the first place to look.

  • A skin rash Additional detail

    “Topically, rose geranium oil has been associated with reports of dermatitis in hypersensitive individuals and burning sensations when applied to the face.”

    Rose Geranium Oil · Natural Medicines adverse-effect record, reported in dermatitis.

    1 source cited
    1. 16653. Greenway FL, Frome BM, Engels TM. Temporary relief of postherpetic neuralgia pain with topical geranium oil. Am J Med 2003;115:586-7. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Rose Geranium Oil — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Naloxegol’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Naloxegol column appears here.

How to take them

Some Naloxegol Products Have a Food Rule — Rose Geranium Oil Should Not Break It

At least one FDA label for a product containing Naloxegol says to take it on an empty stomach. Most supplements — Rose Geranium Oil included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Naloxegol on its own and move Rose Geranium Oil to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Naloxegol products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

(2.1) Take on an empty stomach at least 1 hour prior to the first meal of the day or 2 hours after the meal.

From the Dosage and Administration section of the FDA label we read for Naloxegol — where that label names a specific product, the instruction is that product's. See the Naloxegol drug page ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Naloxegol

This page covers Rose Geranium Oil only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Naloxegol page lists 138 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 94 moderate · 41 minor.

From our pharmacist’s overview on the Naloxegol page

“Naloxegol (Movantik) relieves the constipation that opioids cause, and this is a list that deserves real care before you add anything from it. Nearly all of the trouble traces to a single enzyme, CYP3A4, which the body relies on to clear naloxegol.”

Reviewed by 2 · Jul 18, 2026

Open the Naloxegol interaction page

One more smart check

Taking Rose Geranium Oil as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing Rose Geranium Oil, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Rose Geranium Oil. Even though Rose Geranium Oil itself has no known interaction with Naloxegol, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Rose Geranium Oil and Naloxegol Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Rose Geranium Oil
Steady interest

#1,165 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Naloxegol
Steady interest

#1,582 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Rose Geranium Oil reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Rose Geranium Oil and Naloxegol records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Rose Geranium Oil

What is Rose Geranium Oil?

  • Skin care and complexion
  • Aromatherapy for stress and mood
  • Insect and tick repellent
  • Minor wound and skin soothing
  • Fragrance

Rose geranium oil is an essential oil distilled from the leaves of Pelargonium graveolens, used mainly in aromatherapy, skincare, and as a natural fragrance. High-quality human evidence for medical benefits is limited, and like all essential oils it must be diluted before skin use and never swallowed. Talk to a pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have sensitive skin.

Pelargonium graveolens · Geraniaceae · Leaves and stems (steam-distilled essential oil) · Essential oil, diluted topical blends, aromatherapy products, soaps and skincare items

An interaction check asks whether these two react with each other — it does not ask whether Rose Geranium Oil is a good idea for someone in your situation. Here is what our Rose Geranium Oil record says about it on its own.

Rose Geranium Oil: dosing

There is no established standardized medical dose for rose geranium oil. It is used mainly topically (in diluted form) or by inhaling its scent, not by mouth.For skin use, essential oils are typically mixed at a low concentration in a carrier oil, but you should follow the specific instructions on your product label.

From our Rose Geranium Oil monograph — the full record covers uses, side effects and every documented interaction.

Read the full Rose Geranium Oil monograph & all interactions
Medication

About Naloxegol

What Is Naloxegol Used For?

Brand name: Movantik

Movantik (naloxegol) is used to treat opioid-induced constipation (OIC) — constipation caused by opioid pain medications — in adults who have chronic non-cancer pain. It is also approved for adults with chronic pain related to prior cancer or its treatment, as long as they don't need frequent (roughly weekly) increases in their opioid dose.

It is not indicated for constipation from other causes, and it is not approved for use in children.

Most-Reported Side Effects for Naloxegol

From FAERS, the FDA’s public side-effect reporting system (3,902 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Diarrhea 380 reports
Constipation 375 reports
Nausea 329 reports
Abdominal pain 258 reports
Abdominal pain upper 228 reports
See full Naloxegol drug information
Keep checking

Other Drugs & Rose Geranium Oil

Browse every other medication we’ve checked against Rose Geranium Oil — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Rose Geranium Oil References

The 1 references that drive our Rose Geranium Oil monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Greenway FL, Frome BM, Engels TM. Temporary relief of postherpetic neuralgia pain with topical geranium oil. Am J Med 2003;115:586-7. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Rose Geranium Oil and Naloxegol Together: Common Questions

Is it safe to take Rose Geranium Oil with Naloxegol?
We do not list a known interaction between Rose Geranium Oil and Naloxegol. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Rose Geranium Oil and Naloxegol at the same time of day?
At least one FDA label for a product containing Naloxegol says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Naloxegol on its own and move Rose Geranium Oil to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
Does Naloxegol interact with any supplements?
Yes. Naloxegol has documented interactions with 138 supplements in our database — Rose Geranium Oil is not one of them. The Naloxegol interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Naloxegol and Rose Geranium Oil?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.