Rupturewort + Magnesium Hydroxide (OTC drug)
Magnesium Hydroxide (OTC drug) brand name: Milk of Magnesia (MOM).
We found no known interaction between Rupturewort and Magnesium Hydroxide (OTC drug) in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Rupturewort and Magnesium Hydroxide (OTC drug)
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Magnesium Hydroxide (OTC drug) and Rupturewort in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Rupturewort safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Magnesium Hydroxide (OTC drug)
Interactions in our licensed database are recorded against drug classes, not just single drug names. Magnesium Hydroxide (OTC drug) is filed under 2 classifications — stimulant laxatives, oral drugs. Rupturewort has documented interactions with 1 drug class — the most serious being lithium (moderate) — and none of Magnesium Hydroxide (OTC drug)’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Rupturewort Does Interact With Other Medications
Rupturewort has 1 moderate known drug interaction in our database — Magnesium Hydroxide (OTC drug) isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Rupturewort
We haven’t checked that one against Rupturewort yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Rupturewort. Pick one to open its full report.
See Every Supplement That Interacts With Magnesium Hydroxide (OTC drug)
This page covers Rupturewort only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Magnesium Hydroxide (OTC drug) page lists 46 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Jalap (major), Oleander (major), Alder Buckthorn (moderate) and Aloe (moderate).
By severity: 3 major · 34 moderate · 9 minor.
From our pharmacist’s overview on the Magnesium Hydroxide (OTC drug) page
“Milk of magnesia (magnesium hydroxide) is the medicine-cabinet fix for constipation, and most of the 46 supplements known to interact with it come from the same shelf. Twenty-nine are herbal stimulant laxatives, aloe latex and cascara sagrada among them, and doubling up on laxatives can drain fluid and potassium fast.”
Reviewed by 2 · Jul 18, 2026
Taking Rupturewort as Part of a Dietary Supplement Product? Check It for Interactions
We hold 19 real supplement products containing Rupturewort, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Rupturewort. Even though Rupturewort itself has no known interaction with Magnesium Hydroxide (OTC drug), another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Rupturewort and Magnesium Hydroxide (OTC drug) Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#868 of 1,452 supplements looked up here in the last 7 days
#1,568 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Rupturewort reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Rupturewort and Magnesium Hydroxide (OTC drug) records this page draws on were last updated June 22, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Rupturewort
What is Rupturewort?
- Urinary tract complaints
- Mild fluid retention (as a diuretic)
- Kidney and bladder support
- Wound healing and inflammation (topical, traditional)
- Spasms or cramping (traditional)
Rupturewort is a traditional European herb mainly used as a mild diuretic and for urinary complaints. Solid human research is very limited, so its true benefits and long-term safety are not well established. Talk to a pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.
Herniaria glabra · Caryophyllaceae · Aerial parts (the above-ground flowering herb) · Tea, dried herb, tincture, capsules
An interaction check asks whether these two react with each other — it does not ask whether Rupturewort is a good idea for someone in your situation. Here is what our Rupturewort record says about it on its own.
Rupturewort: dosing
There is no well-established or standardized dose for rupturewort. Traditional use involves brewing the dried herb as a tea, but reliable dosing guidance from clinical research does not exist.If you choose to use a product, follow the directions on the label and do not exceed them.
From our Rupturewort monograph — the full record covers uses, side effects and every documented interaction.
Other Drugs & Rupturewort
Browse every other medication we’ve checked against Rupturewort — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
1 interaction
No interaction 2,828 drugs checked — show the list
We also checked Rupturewort against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Metoprolol ›
- Aspirin ›
- Ivermectin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Escitalopram ›
- Tadalafil ›
- Acetaminophen ›
- Clopidogrel ›
- Valacyclovir ›
- Atorvastatin ›
- Docusate ›
- Hydroxyurea ›
- Abemaciclib ›
- Methamphetamine ›
- Ibuprofen ›
- Sumatriptan ›
- Semaglutide ›
- Tirzepatide ›
- Warfarin Sodium ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Acyclovir ›
- Bupropion ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Bendamustine ›
- Amitriptyline ›
- Doxycycline ›
- Lamotrigine ›
- Fluoxetine ›
- Methotrexate ›
- Acetaminophen, Codeine ›
- Gabapentin ›
- Amphetamine ›
- Pregabalin ›
- Isotretinoin ›
- Dextroamphetamine ›
- Azithromycin ›
- Clonazepam ›
- Quetiapine ›
- Omeprazole ›
- Amlodipine Besylate ›
- Methylene Blue ›
- Duloxetine ›
- Letrozole ›
- Buspirone ›
- Citalopram ›
- Ciprofloxacin ›
- Naproxen ›
Showing the 60 most looked-up of 2,828 medications checked with no known interaction — see the full Rupturewort list.
Rupturewort References
The 1 references that drive our Rupturewort monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Hakim EM, Sivak KV, Kaukhova IE. Evaluation of the diuretic effect of crude ethanol and saponin-rich extracts of Herniaria glabra L. in rats. J Ethnopharmacol. 2021 Jun 12;273:113942. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Magnesium Hydroxide (OTC drug) Is Linked to Lower Levels of 3 Nutrients
Natural Medicines records Magnesium Hydroxide (OTC drug) as a medicine that can lower these. This is not an interaction with Rupturewort — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Magnesium Hydroxide (OTC drug) nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Rupturewort and Magnesium Hydroxide (OTC drug) Together: Common Questions
Is it safe to take Rupturewort with Magnesium Hydroxide (OTC drug)?
How was the Rupturewort and Magnesium Hydroxide (OTC drug) combination checked?
Does Rupturewort interact with any other medications?
Does Magnesium Hydroxide (OTC drug) interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.