Scotch Broom + Haloperidol
Haloperidol brand name: Haldol.
Scotch Broom has a major interaction with Haloperidol. Haloperidol (Haldol) inhibits sparteine metabolism, increasing the risk of adverse effects including circulatory collapse.
Read the full interaction reportScotch Broom and Haloperidol
Here is the interaction we found between these two, with the evidence behind it.
HALOPERIDOL (Haldol)
Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports..
Here's the concern with combining Scotch Broom and haloperidol (Haldol). Scotch Broom contains an alkaloid called sparteine, and your body clears sparteine using an enzyme (CYP2D6) that haloperidol can block. When haloperidol slows that breakdown, sparteine can build up in your system. Since sparteine affects the heart, higher levels raise the risk of serious problems like an irregular heartbeat, a big drop in blood pressure, or even circulatory collapse.
I'll be honest, this is rated as a theoretical interaction based on how these substances behave, not on lots of patient reports. But because the worst-case outcome is so serious, and Scotch Broom has no proven benefit anyway, this is a pairing I'd steer clear of. Please check with your pharmacist or doctor before using it.
- Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
What These Ratings Mean
Every interaction above is graded three ways — here’s the key to each label.
Clinically significant. Avoid the combination, or use only under close professional supervision.
Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.
Generally not serious. Be aware of it and mention it to your pharmacist.
- LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
- ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
- UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
- AHigh-quality meta-analysis (quantitative systematic review).
- BCase-control study.
- CConsensus.
- DAnecdotal evidence.
These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.
Scotch Broom Also Interacts With Other Medications
Scotch Broom has 10 major, 1 moderate known drug interactions in our database — the Haloperidol one above is one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Scotch Broom
We haven’t checked that one against Scotch Broom yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Scotch Broom. Pick one to open its full report.
See Every Supplement That Interacts With Haloperidol
This page covers Scotch Broom only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Haloperidol page lists 211 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).
By severity: 11 major · 157 moderate · 43 minor.
From our pharmacist’s overview on the Haloperidol page
“Haloperidol (Haldol) is a potent antipsychotic prescribed for schizophrenia and severe agitation, and the 211 supplements on this list warrant genuine care, starting with the 11 rated major. Most of the trouble runs through the liver enzymes that clear haloperidol from the body.”
Reviewed by 2 · Jul 18, 2026
Taking Scotch Broom as Part of a Dietary Supplement Product? Check It for Interactions
We hold 6 real supplement products containing Scotch Broom, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Scotch Broom. Your product may carry other ingredients that interact with Haloperidol too, on top of Scotch Broom — and those would not show on this page. Find your product and we’ll check every ingredient on its label:
Where Scotch Broom and Haloperidol Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#349 of 1,452 supplements looked up here in the last 7 days
#1,343 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
About Scotch Broom
What is Scotch Broom?
- Heart rhythm and circulation complaints
- Diuretic (increasing urine)
- Heavy menstrual bleeding
- Mild swelling
- Traditional folk remedy
Scotch Broom is a flowering shrub that has been used in folk medicine for heart and circulation complaints, but it contains potentially toxic alkaloids and there is no solid scientific evidence that it works for any condition. Because it can affect heart rate and blood pressure and may be dangerous in higher amounts, most people should avoid it, and it should never be used during pregnancy or breastfeeding. Always talk with a pharmacist or doctor before trying it.
About Haloperidol
What Is Haloperidol Used For?
Brand name: Haldol
Haloperidol is used to manage symptoms of psychotic disorders and to control the tics and vocal outbursts of Tourette's disorder in both children and adults.
In children, it is also used for severe combative or explosive behavior problems, and for hyperactivity with conduct disorders — but only when other treatments like therapy or non-antipsychotic medications have not worked.
Other Drugs & Scotch Broom
Browse every other medication we’ve checked against Scotch Broom — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
10 interactions
1 interaction
No interaction 2,818 drugs checked — show the list
We also checked Scotch Broom against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Metoprolol ›
- Aspirin ›
- Ivermectin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Escitalopram ›
- Tadalafil ›
- Acetaminophen ›
- Clopidogrel ›
- Valacyclovir ›
- Atorvastatin ›
- Docusate ›
- Hydroxyurea ›
- Abemaciclib ›
- Methamphetamine ›
- Sumatriptan ›
- Ibuprofen ›
- Semaglutide ›
- Tirzepatide ›
- Warfarin Sodium ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Acyclovir ›
- Bupropion ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Bendamustine ›
- Amitriptyline ›
- Doxycycline ›
- Lamotrigine ›
- Fluoxetine ›
- Methotrexate ›
- Acetaminophen, Codeine ›
- Gabapentin ›
- Pregabalin ›
- Isotretinoin ›
- Dextroamphetamine ›
- Azithromycin ›
- Clonazepam ›
- Quetiapine ›
- Omeprazole ›
- Amlodipine Besylate ›
- Methylene Blue ›
- Duloxetine ›
- Letrozole ›
- Buspirone ›
- Citalopram ›
- Ciprofloxacin ›
- Naproxen ›
- Bisoprolol ›
Showing the 60 most looked-up of 2,818 medications checked with no known interaction — see the full Scotch Broom list.
Sources & How We Checked
Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference for vitamins, herbs and supplements — the basis for our interaction data.
- MedlinePlus, U.S. National Library of Medicine — NIH consumer drug information, used for the medication overviews.
- NIH Dietary Supplement Label Database (DSLD) — Official supplement product labels.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Taking Scotch Broom and Haloperidol Together: Common Questions
Can you take Scotch Broom with Haloperidol?
How serious is the Scotch Broom and Haloperidol interaction?
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.