Spotted Geranium + Doxylamine Succinate, Pyridoxine Hydrochloride
Doxylamine Succinate, Pyridoxine Hydrochloride brand names: Diclegis, Bonjesta.
We found no known interaction between Spotted Geranium and Doxylamine Succinate, Pyridoxine Hydrochloride in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Doxylamine Succinate, Pyridoxine Hydrochloride states a food rule worth keeping to.
Spotted Geranium and Doxylamine Succinate, Pyridoxine Hydrochloride
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Doxylamine Succinate, Pyridoxine Hydrochloride and Spotted Geranium in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Spotted Geranium at all — not against Doxylamine Succinate, Pyridoxine Hydrochloride, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Spotted Geranium safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Some Doxylamine Succinate, Pyridoxine Hydrochloride Products Have a Food Rule — Spotted Geranium Should Not Break It
At least one FDA label for a product containing Doxylamine Succinate, Pyridoxine Hydrochloride says to take it on an empty stomach. Most supplements — Spotted Geranium included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Doxylamine Succinate, Pyridoxine Hydrochloride on its own and move Spotted Geranium to a meal later in the day.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Doxylamine Succinate, Pyridoxine Hydrochloride products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
Take on an empty stomach with a glass of water [ see Clinical Pharmacology (12.3) ].
From the Dosage and Administration section of the FDA label we read for Doxylamine Succinate, Pyridoxine Hydrochloride — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
See Every Supplement That Interacts With Doxylamine Succinate, Pyridoxine Hydrochloride
This page covers Spotted Geranium only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Doxylamine Succinate, Pyridoxine Hydrochloride page lists 46 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Henbane (major), Scopolia (major), Angel's Trumpet (moderate) and Bacopa (moderate).
By severity: 3 major · 32 moderate · 11 minor.
From our pharmacist’s overview on the Doxylamine Succinate, Pyridoxine Hydrochloride page
“If you take doxylamine and pyridoxine (Diclegis, Bonjesta) for pregnancy nausea, this list deserves genuine care, because three of its 46 entries carry a major rating. The risk splits two ways.”
Reviewed by 2 · Jul 18, 2026
Open the Doxylamine Succinate, Pyridoxine Hydrochloride interaction page
Taking Spotted Geranium as Part of a Dietary Supplement Product? Check It for Interactions
We hold 2 real supplement products containing Spotted Geranium, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Spotted Geranium. Even though Spotted Geranium itself has no known interaction with Doxylamine Succinate, Pyridoxine Hydrochloride, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Spotted Geranium and Doxylamine Succinate, Pyridoxine Hydrochloride Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,087 of 1,452 supplements looked up here in the last 7 days
#952 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Spotted Geranium is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Spotted Geranium reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Spotted Geranium and Doxylamine Succinate, Pyridoxine Hydrochloride records this page draws on were last updated June 22, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Spotted Geranium
What is Spotted Geranium?
- Diarrhea
- Mouth and throat sores
- Bleeding and wound care
- Hemorrhoids
- Sore throat gargle
Spotted Geranium (Geranium maculatum), also called wild geranium or cranesbill, is a North American woodland plant whose tannin-rich root has long been used in folk medicine as an astringent for diarrhea, minor bleeding, and mouth or throat irritation. Modern human studies are very limited, so its effectiveness is largely unproven. Talk to your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.
Geranium maculatum · Geraniaceae · Root and rhizome (sometimes the dried leaves) · Dried root, tea, tincture, powder, capsules
An interaction check asks whether these two react with each other — it does not ask whether Spotted Geranium is a good idea for someone in your situation. Here is what our Spotted Geranium record says about it on its own.
Spotted Geranium: dosing
There is no established standard dose for Spotted Geranium. Traditional use involved teas, tinctures, and gargles made from the dried root, but amounts varied widely and were not standardized.If you choose to use a commercial product, follow the directions on the label and do not exceed them.
From our Spotted Geranium monograph — the full record covers uses, side effects and every documented interaction.
About Doxylamine and Pyridoxine
What Is Doxylamine and Pyridoxine Used For?
Brand names: Diclegis, Bonjesta
Doxylamine and pyridoxine is indicated for the treatment of nausea and vomiting of pregnancy in women who do not respond to conservative management. This applies to the delayed-release tablets (including Diclegis and the generic doxylamine succinate and pyridoxine hydrochloride delayed-release tablets) as well as to Bonjesta, the extended-release tablet formulation.
None of these products have been studied in women with hyperemesis gravidarum (severe, persistent vomiting in pregnancy), so their use in that setting is not established.
Other Drugs & Spotted Geranium
Browse every other medication we’ve checked against Spotted Geranium — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Spotted Geranium against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Amlodipine ›
- Levothyroxine ›
- Methylphenidate ›
- Warfarin ›
- Abemaciclib ›
- Ivermectin ›
- Testosterone ›
- Sertraline ›
- Acetaminophen ›
- Losartan Potassium ›
- Aspirin ›
- Rosuvastatin ›
- Metoprolol ›
- Escitalopram ›
- Clopidogrel ›
- Rivaroxaban ›
- Atorvastatin ›
- Methamphetamine ›
- Tirzepatide ›
- Isotretinoin ›
- Warfarin Sodium ›
- Ibuprofen ›
- Docusate ›
- Sumatriptan ›
- Valacyclovir ›
- Tadalafil ›
- Amlodipine Besylate ›
- Hydroxyurea ›
- Prednisone ›
- Semaglutide ›
- Metformin ›
- Lisdexamfetamine ›
- Amitriptyline ›
- Propranolol ›
- Amphetamine ›
- Methotrexate ›
- Amoxicillin ›
- Lisinopril ›
- Bupropion ›
- Levothyroxine, Liothyronine ›
- Fluoxetine ›
- Bendamustine ›
- Doxycycline ›
- Azithromycin ›
- Pregabalin ›
- Lamotrigine ›
- Acyclovir ›
- Dextroamphetamine ›
- Gabapentin ›
- Naproxen ›
- Quetiapine ›
- Clonazepam ›
- Buspirone ›
- Omeprazole ›
- Acetaminophen, Codeine ›
- Duloxetine ›
- Letrozole ›
- Citalopram ›
- Methylene Blue ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Spotted Geranium list.
Spotted Geranium References
The 1 sources that drive our Spotted Geranium monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Spotted Geranium is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.
- Herbs at a Glance — NIH NCCIH Source
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Spotted Geranium and Doxylamine Succinate, Pyridoxine Hydrochloride Together: Common Questions
Is it safe to take Spotted Geranium with Doxylamine Succinate, Pyridoxine Hydrochloride?
Should I take Spotted Geranium and Doxylamine Succinate, Pyridoxine Hydrochloride at the same time of day?
Does Doxylamine Succinate, Pyridoxine Hydrochloride interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.