Superoxide Dismutase (sod) + Pralsetinib
Pralsetinib brand name: Gavreto.
We found no known interaction between Superoxide Dismutase (sod) and Pralsetinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Pralsetinib states a food rule worth keeping to.
Superoxide Dismutase (sod) and Pralsetinib
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Pralsetinib and Superoxide Dismutase (sod) in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Superoxide Dismutase (sod) at all — not against Pralsetinib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Superoxide Dismutase (sod) safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Some Pralsetinib Products Have a Food Rule — Superoxide Dismutase (sod) Should Not Break It
At least one FDA label for a product containing Pralsetinib says to take it on an empty stomach. Most supplements — Superoxide Dismutase (sod) included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Pralsetinib on its own and move Superoxide Dismutase (sod) to a meal later in the day.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Pralsetinib products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
( 2.1 , 14 ) The recommended dosage in adults and pediatric patients 12 years and older is 400 mg orally once daily on an empty stomach (no food intake for at least 2 hours before and at least 1 hour after taking GAVRETO).
From the Dosage and Administration section of the FDA label we read for Pralsetinib — where that label names a specific product, the instruction is that product's. See the Pralsetinib drug page ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
See Every Supplement That Interacts With Pralsetinib
This page covers Superoxide Dismutase (sod) only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Pralsetinib page lists 181 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Beer (major) and Cesium (major).
By severity: 11 major · 134 moderate · 36 minor.
From our pharmacist’s overview on the Pralsetinib page
“With pralsetinib (Gavreto), a targeted therapy for RET-driven lung and thyroid cancers, I would treat this list as required reading rather than background noise. Most of the interactions change how much of the drug the body actually gets: grapefruit can push its levels higher, while St.”
Reviewed by 2 · Jul 18, 2026
Where Superoxide Dismutase (sod) and Pralsetinib Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,416 of 1,452 supplements looked up here in the last 7 days
#1,755 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Superoxide Dismutase (sod) reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Superoxide Dismutase (sod) and Pralsetinib records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Superoxide Dismutase (sod)
What is Superoxide Dismutase (sod)?
- Antioxidant support
- Anti-aging and skin health
- Joint pain and arthritis
- Exercise recovery and oxidative stress
- General inflammation
Superoxide dismutase (SOD) is a natural antioxidant enzyme your body makes to help neutralize harmful free radicals. While it has clear biological importance, oral supplements may be broken down during digestion, and strong human evidence that taking SOD supplements improves health is limited. Talk to your pharmacist or doctor before using it, especially if you are pregnant or have a health condition.
Enzyme sourced from plants (such as cantaloupe melon), bovine liver, or made by microbes; also produced naturally in the body · Capsules, tablets, topical creams, injectable forms (used in some research settings)
An interaction check asks whether these two react with each other — it does not ask whether Superoxide Dismutase (sod) is a good idea for someone in your situation. Here is what our Superoxide Dismutase (sod) record says about it on its own.
Superoxide Dismutase (sod): dosing
There is no well-established standard dose for superoxide dismutase supplements. Doses vary widely between products and forms.The best advice is to follow the directions on the product label and not exceed the recommended amount.
From our Superoxide Dismutase (sod) monograph — the full record covers uses, side effects and every documented interaction.
About Pralsetinib
What Is Pralsetinib Used For?
Brand name: Gavreto
Gavreto (pralsetinib) is used to treat adults with metastatic RET fusion-positive non-small cell lung cancer (NSCLC) — a type of lung cancer that has spread and carries a specific genetic alteration detected by an FDA-approved test.
Gavreto is also approved for adults and children aged 12 and older with advanced or metastatic RET fusion-positive thyroid cancer who need systemic (whole-body) treatment and whose cancer no longer responds to radioactive iodine (when radioactive iodine is an appropriate option). This thyroid cancer use is under accelerated approval, meaning continued approval depends on results from confirmatory clinical trials.
Most-Reported Side Effects for Pralsetinib
From FAERS, the FDA’s public side-effect reporting system (1,788 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Superoxide Dismutase (sod)
Browse every other medication we’ve checked against Superoxide Dismutase (sod) — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Superoxide Dismutase (sod) against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Warfarin ›
- Methylphenidate ›
- Sertraline ›
- Testosterone ›
- Ivermectin ›
- Losartan Potassium ›
- Abemaciclib ›
- Aspirin ›
- Acetaminophen ›
- Metoprolol ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Docusate ›
- Tadalafil ›
- Tirzepatide ›
- Methamphetamine ›
- Ibuprofen ›
- Warfarin Sodium ›
- Valacyclovir ›
- Hydroxyurea ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Amitriptyline ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Amlodipine Besylate ›
- Bendamustine ›
- Methotrexate ›
- Bupropion ›
- Amphetamine ›
- Fluoxetine ›
- Doxycycline ›
- Azithromycin ›
- Acyclovir ›
- Pregabalin ›
- Lamotrigine ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Levothyroxine, Liothyronine ›
- Clonazepam ›
- Quetiapine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Duloxetine ›
- Methylene Blue ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Superoxide Dismutase (sod) list.
Superoxide Dismutase (sod) References
The 2 references that drive our Superoxide Dismutase (sod) monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
- Nielsen OS, Overgaard J, Overgaard M, et al. Orgotein in radiation treatment of bladder cancer. A report on allergic reactions and lack of radioprotective effect. Acta Oncol 1987;26:101-4. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Superoxide Dismutase (sod) and Pralsetinib Together: Common Questions
Is it safe to take Superoxide Dismutase (sod) with Pralsetinib?
Should I take Superoxide Dismutase (sod) and Pralsetinib at the same time of day?
Does Pralsetinib interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.