Drug & supplement interaction

Tarragon + Ketoconazole

Ketoconazole brand name: Nizoral.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Tarragon and Ketoconazole in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Tarragon and Ketoconazole

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Ketoconazole and Tarragon in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Tarragon safety at a glance

Tarragon overall Use caution Food amounts are generally safe, but concentrated extracts and essential oil should be used cautiously due to estragole content.
Pregnancy Likely Unsafe Insufficient reliable information is available; avoid using. Read the full pregnancy detail
Breastfeeding Likely Unsafe Insufficient reliable information is available; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Ketoconazole and Tarragon? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Ketoconazole

Interactions in our licensed database are recorded against drug classes, not just single drug names. Ketoconazole is filed under 8 classifications — including antifungals, cytochrome p450 2c19 (cyp2c19) inhibitors, cytochrome p450 2c9 (cyp2c9) inhibitors. Tarragon has documented interactions with 3 drug classes — the most serious being anticoagulant/antiplatelet drugs (moderate), cns depressants (moderate) and monoamine oxidase inhibitors (maois) (moderate) — and none of Ketoconazole’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Tarragon Does Interact With Other Medications

Tarragon has 359 moderate known drug interactions in our database — Ketoconazole isn’t one of them. If you take anything else, check it against the full list below.

Moderate 359 No known interaction 2,471 (incl. Ketoconazole)
Taking anything else?

Check Another of Your Medications Against Tarragon

Covers the 2,830 medications we’ve checked against Tarragon. Pick one to open its full report.

What to actually watch for

What Ketoconazole’s Own FDA Label Lists

This is not an interaction — none of it involves Tarragon. These are the most notable effects listed in the ADVERSE REACTIONS section of Ketoconazole’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 7 of them are worth acting on rather than waiting out — marked below.

  • Yellowing of the skin or eyes Worth acting on
  • A severe skin reaction Worth acting on
  • A low platelet count Worth acting on
  • A severe allergic reaction Worth acting on
  • Hives Worth acting on
  • Liver problems Worth acting on
  • Bleeding or bruising Worth acting on
  • Increased appetite
  • Changes to your period
  • Breast tenderness

Showing the 10 most notable of 38 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Ketoconazole. Read the label on DailyMed › Tarragon’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Tarragon side to compare — that is a limit of the record, not a statement that Tarragon has no side effects.

Special populations

Tarragon in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Unsafe

Insufficient reliable information is available; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

From our Q&A

Questions About Tarragon or Ketoconazole

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Tarragon or Ketoconazole, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Ketoconazole

This page covers Tarragon only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ketoconazole page lists 182 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Grapefruit (major), Siberian Cocklebur (major) and St. John's Wort (major).

By severity: 6 major · 135 moderate · 41 minor.

From our pharmacist’s overview on the Ketoconazole page

“Ketoconazole (Nizoral) is already hard on the liver, so treat its 182 interacting supplements with genuine care, starting with the six rated major. Most of the list runs through CYP3A4, the liver enzyme ketoconazole strongly blocks, so it can raise levels of over a hundred herbal ingredients, while grapefruit pushes ketoconazole itself…”

Reviewed by 2 · Jul 18, 2026

Open the Ketoconazole interaction page

One more smart check

Taking Tarragon as Part of a Dietary Supplement Product? Check It for Interactions

We hold 36 real supplement products containing Tarragon, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Tarragon. Even though Tarragon itself has no known interaction with Ketoconazole, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Tarragon and Ketoconazole Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Tarragon
Top half

#573 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Ketoconazole
Steady interest

#1,996 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Tarragon reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Tarragon and Ketoconazole records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Tarragon

What is Tarragon?

Tarragon
  • Digestive upset
  • Appetite stimulation
  • Sleep and mild restlessness
  • Toothache and oral discomfort
  • Blood sugar support (preliminary)
  • Culinary flavoring

Tarragon is a flavorful culinary herb that has been used in traditional medicine for digestion, sleep, and other complaints, but solid human evidence for any health benefit is lacking. Amounts used in cooking are generally considered safe, while concentrated extracts and the essential oil should be used cautiously because tarragon contains estragole, a compound studied for possible safety concerns. Talk to your pharmacist or doctor before using tarragon as a supplement.

Artemisia dracunculus · Asteraceae · Leaves and essential oil · Fresh or dried herb (culinary), tea, essential oil, extracts, capsules

An interaction check asks whether these two react with each other — it does not ask whether Tarragon is a good idea for someone in your situation. Here is what our Tarragon record says about it on its own.

Tarragon: dosing

There is no well-established medicinal dose for tarragon. As a food, it is used freely as a seasoning. As a tea, it is usually made by steeping a small amount of dried or fresh leaves in hot water.For capsules, extracts, or essential oil, follow the directions on the product label and do not exceed them. Because product strengths vary and estragole content can differ, it is best to use these products only with guidance from a pharmacist or doctor. Never take the essential oil internally unless specifically directed by a qualified healthcare professional.

From our Tarragon monograph — the full record covers uses, side effects and every documented interaction.

Read the full Tarragon monograph & all interactions
Medication

About Ketoconazole

What Is Ketoconazole Used For?

Brand name: Nizoral

Ketoconazole 2% shampoo and foam are used to treat tinea versicolor (also called pityriasis versicolor) — a fungal infection caused by Pityrosporum orbiculare (also known as Malassezia furfur), a yeast that naturally lives on the skin.

This infection creates light or dark patches, most often on the trunk, neck, arms, and upper thighs. Even after the fungus is cleared, those skin patches may take months to return to their normal color — that's normal, and depends on your skin type and sun exposure. Tinea versicolor can also come back, since the fungus lives on healthy skin even when there's no active infection.

Most-Reported Side Effects for Ketoconazole

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Pruritus 984 reports
Fatigue 975 reports
Nausea 873 reports
Rash 858 reports
Diarrhea 814 reports
See full Ketoconazole drug information
Keep checking

Other Drugs & Tarragon

Browse every other medication we’ve checked against Tarragon — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
359Moderate
0Minor
2,470No known interaction
359 Moderate 2,470 No interaction
Moderate

359 interactions

Showing 60 of 359 moderate interactions — see all 359 on the Tarragon page.

No interaction 2,470 drugs checked — show the list

We also checked Tarragon against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,470 medications checked with no known interaction — see the full Tarragon list.

See the full Tarragon interactions page
See every supplement checked against Ketoconazole, ranked by severity
Evidence & sources

Tarragon References

The 9 references that drive our Tarragon monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  2. Yazdanparast, R. and Shahriyary, L. Comparative effects of Artemisia dracunculus, Satureja hortensis and Origanum majorana on inhibition of blood platelet adhesion, aggregation and secretion. Vascul.Pharmacol 2008;48(1):32-37. PubMed
  3. Sayyah, M., Nadjafnia, L., and Kamalinejad, M. Anticonvulsant activity and chemical composition of Artemisia dracunculus L. essential oil. J Ethnopharmacol. 2004;94(2-3):283-287. PubMed
  4. Vasil'ev, E. D., Il'nitskaia, S. I., Nikitenko, E. V., and Kaledin, V. I. [Age- and sex-related differences in sensitivity to hepatotoxic action of estragole in mice]. Ross.Fiziol.Zh.Im I.M.Sechenova 2005;91(9):1066-1070.
  5. Shahriyary, L. and Yazdanparast, R. Inhibition of blood platelet adhesion, aggregation and secretion by Artemisia dracunculus leaves extracts. J Ethnopharmacol. 11-1-2007;114(2):194-198. PubMed
  6. Drinkwater, N. R., Miller, E. C., Miller, J. A., and Pitot, H. C. Hepatocarcinogenicity of estragole (1-allyl-4-methoxybenzene) and 1'-hydroxyestragole in the mouse and mutagenicity of 1'-acetoxyestragole in bacteria. J Natl.Cancer Inst. 1976;57(6):1323-
  7. Kaledin, V. I., Pakharukova, M. Y., Pivovarova, E. N., Kropachev, K. Y., Baginskaya, N. V., Vasilieva, E. D., Ilnitskaya, S. I., Nikitenko, E. V., Kobzev, V. F., and Merkulova, T. I. Correlation between hepatocarcinogenic effect of estragole and its infl
  8. de Pradier E. A trial of a mixture of three essential oils in the treatment of postoperative nausea and vomiting. International Journal of Aromatherapy 2006;16(1):15-20. DOI
  9. Aydin T, Akincioglu H, Gumustas M, Gulcin I, Kazaz C, Cakir A. Human monoamine oxidase (hMAO) A and hMAO B inhibitors from Artemisia dracunculus L. herniarin and skimmin: human mononamine oxidase A and B inhibitors from A. dracunculus L. Z Naturforsch C J

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Tarragon and Ketoconazole Together: Common Questions

Is it safe to take Tarragon with Ketoconazole?
We do not list a known interaction between Tarragon and Ketoconazole. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Tarragon and Ketoconazole combination checked?
Interactions in our licensed database are recorded against drug classes. Ketoconazole is filed under 8 classifications, and Tarragon has documented interactions with 3 drug classes — none of Ketoconazole's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Tarragon interact with any other medications?
Yes. Tarragon has 359 documented drug interactions in our database — Ketoconazole is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Ketoconazole interact with any supplements?
Yes. Ketoconazole has documented interactions with 182 supplements in our database — Tarragon is not one of them. The Ketoconazole interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Tarragon monograph Uses, safety profile, and every drug interaction in one place Ketoconazole drug information The full plain-English guide to this medication Ketoconazole supplement interactions Every supplement checked against Ketoconazole, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 9 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Ketoconazole and Tarragon?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.