Tormentil + Sirolimus (albumin bound)
Sirolimus (albumin bound) brand name: Fyarro.
We found no known interaction between Tormentil and Sirolimus (albumin bound) in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
Tormentil and Sirolimus (albumin bound)
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Sirolimus (albumin bound) and Tormentil in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Tormentil at all — not against Sirolimus (albumin bound), and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Tormentil safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
See Every Supplement That Interacts With Sirolimus (albumin bound)
This page covers Tormentil only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Sirolimus (albumin bound) page lists 171 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate), Active Hexose Correlated Compound (ahcc) (moderate) and Adrafinil (moderate).
By severity: 2 major · 142 moderate · 27 minor.
From our pharmacist’s overview on the Sirolimus (albumin bound) page
“Fyarro, the albumin-bound form of sirolimus used to treat advanced malignant PEComa, a rare cancer, is a medication I would guard carefully from supplement interference, and the 171 ingredients on this page show why. Most of them (121 through the CYP3A4 enzyme, 37 through the P-glycoprotein transporter) can shift how much sirolimus act…”
Reviewed by 2 · Jul 18, 2026
Where Tormentil and Sirolimus (albumin bound) Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#684 of 1,452 supplements looked up here in the last 7 days
#2,637 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Tormentil reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Tormentil and Sirolimus (albumin bound) records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Tormentil
What is Tormentil?
- Diarrhea
- Mouth and throat inflammation
- Mild digestive upset
- Sore throat (gargle)
- Minor wounds and skin irritation
Tormentil is a traditional herb whose root is rich in tannins and has long been used for diarrhea and as a mouth rinse for sore gums or throat. Some small studies suggest it may help shorten diarrhea, but overall evidence is limited and quality is low. Talk to your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding because safety is not established.
Potentilla erecta · Rosaceae · Root and rhizome (underground stem) · Tincture, liquid extract, tea, capsules, mouth rinse
An interaction check asks whether these two react with each other — it does not ask whether Tormentil is a good idea for someone in your situation. Here is what our Tormentil record says about it on its own.
Tormentil: dosing
There is no official, standardized dose for tormentil, and products vary widely in strength. Tinctures, extracts, teas, and capsules will each have different recommended amounts.The safest approach is to follow the directions on the product label and not exceed them. If you are using it as a mouth rinse, do not swallow large amounts.
From our Tormentil monograph — the full record covers uses, side effects and every documented interaction.
About Sirolimus (with albumin) Injection
What Is Sirolimus (with albumin) Injection Used For?
Brand name: Fyarro
Fyarro (sirolimus albumin-bound injection) is approved to treat adult patients with malignant perivascular epithelioid cell tumor (PEComa) — a rare cancer — when it cannot be removed surgically (locally advanced unresectable) or has spread to other parts of the body (metastatic).
Other Drugs & Tormentil
Browse every other medication we’ve checked against Tormentil — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Tormentil against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Metoprolol ›
- Aspirin ›
- Ivermectin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Escitalopram ›
- Tadalafil ›
- Acetaminophen ›
- Clopidogrel ›
- Valacyclovir ›
- Atorvastatin ›
- Docusate ›
- Hydroxyurea ›
- Abemaciclib ›
- Methamphetamine ›
- Ibuprofen ›
- Sumatriptan ›
- Semaglutide ›
- Tirzepatide ›
- Warfarin Sodium ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Acyclovir ›
- Bupropion ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Bendamustine ›
- Amitriptyline ›
- Doxycycline ›
- Lamotrigine ›
- Fluoxetine ›
- Methotrexate ›
- Acetaminophen, Codeine ›
- Gabapentin ›
- Amphetamine ›
- Pregabalin ›
- Isotretinoin ›
- Dextroamphetamine ›
- Azithromycin ›
- Clonazepam ›
- Quetiapine ›
- Omeprazole ›
- Amlodipine Besylate ›
- Methylene Blue ›
- Duloxetine ›
- Buspirone ›
- Letrozole ›
- Citalopram ›
- Ciprofloxacin ›
- Naproxen ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Tormentil list.
Tormentil References
The 1 references that drive our Tormentil monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Huber, R., Ditfurth, A. V., Amann, F., Guthlin, C., Rostock, M., Trittler, R., Kummerer, K., and Merfort, I. Tormentil for active ulcerative colitis: an open-label, dose-escalating study. J.Clin.Gastroenterol. 2007;41(9):834-838. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Tormentil and Sirolimus (albumin bound) Together: Common Questions
Is it safe to take Tormentil with Sirolimus (albumin bound)?
Do Tormentil and Sirolimus (albumin bound) have any of the same side effects?
Does Sirolimus (albumin bound) interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.