Drug & supplement interaction

Wild Carrot + Esketamine

Esketamine brand name: Spravato.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Wild Carrot and Esketamine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Wild Carrot and Esketamine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Esketamine and Wild Carrot in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Wild Carrot safety at a glance

Wild Carrot overall Use caution Generally used in folk medicine, but human safety data are limited and the seeds may carry more risk.
Pregnancy Likely Unsafe When used orally. The seeds, oil, and above ground parts can cause uterine stimulant, abortifacient, and menstrual stimulant effects. BREAST-FEEDING: Read the full pregnancy detail
Breastfeeding Avoid Not enough safety information is available, so it is best avoided while breastfeeding.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Esketamine and Wild Carrot? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Esketamine

Interactions in our licensed database are recorded against drug classes, not just single drug names. Esketamine is filed under 2 classifications — tricyclic antidepressants (tcas), antidepressant drugs. Wild Carrot has documented interactions with 4 drug classes — the most serious being antihypertensive drugs (moderate), estrogens (moderate) and lithium (moderate) — and none of Esketamine’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Wild Carrot Does Interact With Other Medications

Wild Carrot has 475 moderate known drug interactions in our database — Esketamine isn’t one of them. If you take anything else, check it against the full list below.

Moderate 475 No known interaction 2,355 (incl. Esketamine)
Taking anything else?

Check Another of Your Medications Against Wild Carrot

Covers the 2,830 medications we’ve checked against Wild Carrot. Pick one to open its full report.

What to actually watch for

What Wild Carrot Itself Has Been Linked To

This is not an interaction — nothing below involves Esketamine. It is the side-effect record for Wild Carrot on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Wild Carrot, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • An allergic reaction Worth acting on Additional detail

    “Orally, excessive doses of wild carrot seed oil might cause renal irritation or neurological effects. Hypersensitivity reactions and increased sensitivity to UV light and sunburn might also occur (4,19).

    Topically, contact with the plant can cause dermatitis (4).”

    Wild Carrot · Natural Medicines adverse-effect record, reported in dermatitis.

    2 sources cited
    1. 4. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
    2. 19. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

    “Orally, wild carrot seed oil might cause hypersensitivity reactions and increased sensitivity to UV light and sunburn (4,19).”

    Wild Carrot · Natural Medicines adverse-effect record, reported in sunburn.

    2 sources cited
    1. 4. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
    2. 19. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  • Sun sensitivity Additional detail

    Recorded for Wild Carrot in the same Natural Medicines adverse-effect record shown under An allergic reaction above.

  • A skin rash Additional detail

    “Topically, contact with the plant can cause dermatitis (4).”

    Wild Carrot · Natural Medicines adverse-effect record, reported in dermatitis.

    1 source cited
    1. 4. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.

Everything above comes from the Natural Medicines adverse-effect record for Wild Carrot — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Esketamine’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Esketamine column appears here.

Special populations

Wild Carrot in Pregnancy & Breastfeeding

Pregnancy Likely Unsafe

When used orally. The seeds, oil, and above ground parts can cause uterine stimulant, abortifacient, and menstrual stimulant effects. BREAST-FEEDING:

Pregnancy Possibly Unsafe

When the seed oil is used orally. Wild carrot seed oil has mild estrogenic activity and irritant effects. There is insufficient reliable information available about the safety of the oral use of the seeds or above ground parts during lactation.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Esketamine

This page covers Wild Carrot only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Esketamine page lists 11 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Scopolia (major), Cowhage (moderate), Dhea (moderate), Griffonia Simplicifolia (moderate) and Indian Snakeroot (moderate).

By severity: 1 major · 6 moderate · 4 minor.

From our pharmacist’s overview on the Esketamine page

“Esketamine (Spravato) is the nasal spray for depression that hasn't responded to standard treatment, and its supplement list deserves genuine respect. Scopolia carries the only major rating and is the entry to understand before any other; pairing it with the medication can raise the risk of anticholinergic effects, meaning dry mouth, b…”

Reviewed by 2 · Jul 18, 2026

Open the Esketamine interaction page

One more smart check

Taking Wild Carrot as Part of a Dietary Supplement Product? Check It for Interactions

We hold 7 real supplement products containing Wild Carrot, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Wild Carrot. Even though Wild Carrot itself has no known interaction with Esketamine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Wild Carrot and Esketamine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Wild Carrot
Top half

#556 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Esketamine
Steady interest

#2,247 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Wild Carrot reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Wild Carrot and Esketamine records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Wild Carrot

What is Wild Carrot?

Wild Carrot
  • Urinary and bladder complaints
  • Digestive upset and gas
  • Menstrual support
  • Supporting milk production
  • Mild diuretic (water pill) effect

Wild carrot is a traditional herb (the wild ancestor of the garden carrot) used mostly for urinary, digestive, and menstrual complaints. High-quality human studies are lacking, so its benefits are unproven, and it should be avoided in pregnancy because of traditional use to affect the uterus. Talk with your pharmacist or doctor before using it.

Daucus carota · Apiaceae · Seeds, root, leaves, and flowers; sometimes the essential oil · Tea, dried herb, tincture, capsules, seed extract, essential oil

An interaction check asks whether these two react with each other — it does not ask whether Wild Carrot is a good idea for someone in your situation. Here is what our Wild Carrot record says about it on its own.

Wild Carrot: dosing

There is no well-established, standardized dose for wild carrot. Traditional preparations vary widely, and the strength of teas, tinctures, capsules, and seed extracts is not consistent between products.If you choose to use a wild carrot product, follow the directions on the label and do not exceed the recommended amount. Because quality and potency can differ, choose products from reputable brands.

From our Wild Carrot monograph — the full record covers uses, side effects and every documented interaction.

Read the full Wild Carrot monograph & all interactions
Medication

About Esketamine Nasal Spray

What Is Esketamine Nasal Spray Used For?

Brand name: Spravato

Spravato nasal spray is approved for two uses in adults. First, it treats treatment-resistant depression (TRD) — depression that has not responded to other antidepressants — either on its own or alongside an oral antidepressant. Second, it treats depressive symptoms in adults with major depressive disorder (MDD) who have acute suicidal ideation or behavior, always used together with an oral antidepressant in this case.

Important limits: Spravato has not been shown to prevent suicide or reduce suicidal thoughts or behavior on its own. It is not a replacement for hospitalization if that is clinically needed, and it is not approved as an anesthetic.

Most-Reported Side Effects for Esketamine

From FAERS, the FDA’s public side-effect reporting system (17,728 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Dissociation 3,733 reports
Sedation 2,706 reports
Suicidal ideation 1,351 reports
Nausea 957 reports
Depression 873 reports
See full Esketamine Nasal Spray drug information
Keep checking

Other Drugs & Wild Carrot

Browse every other medication we’ve checked against Wild Carrot — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
475Moderate
0Minor
2,354No known interaction
475 Moderate 2,354 No interaction
Moderate

475 interactions

Showing 60 of 475 moderate interactions — see all 475 on the Wild Carrot page.

No interaction 2,354 drugs checked — show the list

We also checked Wild Carrot against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,354 medications checked with no known interaction — see the full Wild Carrot list.

See the full Wild Carrot interactions page
See every supplement checked against Esketamine, ranked by severity
Evidence & sources

Wild Carrot References

The 2 references that drive our Wild Carrot monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Wild Carrot and Esketamine Together: Common Questions

Is it safe to take Wild Carrot with Esketamine?
We do not list a known interaction between Wild Carrot and Esketamine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Wild Carrot and Esketamine combination checked?
Interactions in our licensed database are recorded against drug classes. Esketamine is filed under 2 classifications, and Wild Carrot has documented interactions with 4 drug classes — none of Esketamine's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Wild Carrot interact with any other medications?
Yes. Wild Carrot has 475 documented drug interactions in our database — Esketamine is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Esketamine interact with any supplements?
Yes. Esketamine has documented interactions with 11 supplements in our database — Wild Carrot is not one of them. The Esketamine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Wild Carrot monograph Uses, safety profile, and every drug interaction in one place Esketamine Nasal Spray drug information The full plain-English guide to this medication Esketamine supplement interactions Every supplement checked against Esketamine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Esketamine and Wild Carrot?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.