Drug & supplement interaction

Wild Carrot + Maprotiline

Maprotiline brand name: Ludiomil.

Moderate Interaction
The bottom line Moderate

Wild Carrot has a moderate interaction with Maprotiline. Theoretically, concomitant use might result in increased photosensitivity.

Read the full interaction report
SeverityModerate
LikelihoodProbable
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Wild Carrot and Maprotiline

Here is the interaction we found between these two, with the evidence behind it.

Moderate

PHOTOSENSITIZING DRUGS

Why this applies to Maprotiline

Maprotiline falls under PHOTOSENSITIZING DRUGS — the group Wild Carrot interacts with.

Theoretically, concomitant use might result in increased photosensitivity. Some drugs that cause photosensitivity include amitriptyline (Elavil), quinolones (Ciprofloxacin, others), sulfa drugs (Septra, Bactrim, others), and tetracycline.
Severity Moderate Likelihood Probable Evidence D

Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports..

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the simple version: Maprotiline can already make your skin more sensitive to sunlight, meaning you may sunburn faster or break out in a rash after time outdoors. Wild carrot contains plant compounds that, at least in theory, can do the same thing. Put them together and you might be a little more prone to that sun reaction than with either one alone.

I want to be honest that this is a theoretical concern based on how these compounds behave, not something proven in solid human studies, so I wouldn't lose sleep over it. Still, it's easy to play it safe: wear sunscreen, cover up, and limit strong midday sun. If you'd like to add wild carrot, run it past your pharmacist or doctor first.

References
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Wild Carrot Also Interacts With Other Medications

Wild Carrot has 474 moderate known drug interactions in our database — the Maprotiline one above is one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Wild Carrot

Covers the 2,830 medications we’ve checked against Wild Carrot. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Maprotiline

This page covers Wild Carrot only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Maprotiline page lists 116 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Lithium (major), 1,3-dmaa (moderate), 5-htp (moderate) and Acacia Rigidula (moderate).

By severity: 2 major · 90 moderate · 24 minor.

From our pharmacist’s overview on the Maprotiline page

“The riskiest pairing on this page belongs to lithium. Taken alongside a serotonergic antidepressant like maprotiline (Ludiomil), it can both mask and raise the odds of serotonin syndrome, a dangerous buildup of serotonin activity, and it earns one of the list's two major ratings for that reason.”

Reviewed by 2 · Jul 18, 2026

Open the Maprotiline interaction page

One more smart check

Taking Wild Carrot as Part of a Dietary Supplement Product? Check It for Interactions

We hold 7 real supplement products containing Wild Carrot, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Wild Carrot. Your product may carry other ingredients that interact with Maprotiline too, on top of Wild Carrot — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Wild Carrot and Maprotiline Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Wild Carrot
Steady interest

#1,136 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Maprotiline
Steady interest

#2,185 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Wild Carrot

What is Wild Carrot?

Wild Carrot
  • Urinary and bladder complaints
  • Digestive upset and gas
  • Menstrual support
  • Supporting milk production
  • Mild diuretic (water pill) effect

Wild carrot is a traditional herb (the wild ancestor of the garden carrot) used mostly for urinary, digestive, and menstrual complaints. High-quality human studies are lacking, so its benefits are unproven, and it should be avoided in pregnancy because of traditional use to affect the uterus. Talk with your pharmacist or doctor before using it.

Read the full Wild Carrot monograph & all interactions
Medication

About Maprotiline

What Is Maprotiline Used For?

Brand name: Ludiomil

  • Maprotiline is used to treat depression, bipolar disorder (manic depressive disorder; a disease that causes episodes of depression, episodes of mania, and other abnormal moods), and anxiety. Maprotiline is in a class of medications called tetracyclic antidepressants. It works by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance.

See full Maprotiline drug information
Keep checking

Other Drugs & Wild Carrot

Browse every other medication we’ve checked against Wild Carrot — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
474Moderate
0Minor
2,355No known interaction
Moderate

474 interactions

Showing 60 of 474 moderate interactions — see all 474 on the Wild Carrot page.

No interaction 2,355 drugs checked — show the list
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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Pharmacist Counseling Corner

Taking Wild Carrot and Maprotiline Together: Common Questions

Can you take Wild Carrot with Maprotiline?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Wild Carrot and Maprotiline interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Maprotiline and Wild Carrot?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.