Drug & supplement interaction

Wild Daisy + Progesterone

Progesterone brand name: Milprosa.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Wild Daisy and Progesterone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Wild Daisy and Progesterone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Progesterone and Wild Daisy in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Wild Daisy at all — not against Progesterone, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Wild Daisy safety at a glance

Wild Daisy overall Use caution Limited safety data; allergic reactions are possible, especially in people sensitive to the daisy family.
Pregnancy Avoid Not enough safety information; avoid use during pregnancy.
Breastfeeding Avoid Not enough safety information; avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Progesterone and Wild Daisy? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Progesterone’s Own FDA Label Lists

This is not an interaction — none of it involves Wild Daisy. These are the most notable effects listed in the ADVERSE REACTIONS section of Progesterone’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 2 of them are worth acting on rather than waiting out — marked below.

  • Chest pain Worth acting on
  • Low mood Worth acting on
  • Breast tenderness
  • Flushing
  • Bloating or gas
  • Sweating
  • Joint pain
  • Constipation
  • Swelling
  • Dizziness mentioned in 4.2% of FDA reports for Progesterone

Showing the 10 most notable of 15 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Progesterone. Read the label on DailyMed › Where a percentage is shown, it is the share of 22,512 voluntary FDA FAERS reports for Progesterone that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wild Daisy’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Wild Daisy side to compare — that is a limit of the record, not a statement that Wild Daisy has no side effects.

Overlapping uses

What Progesterone Is Prescribed For, and What Wild Daisy Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Progesterone is a prescription medicine with approved uses on its FDA label. Wild Daisy is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Progesterone is prescribed for: Progesterone capsules (including Prometrium) are used to prevent endometrial hyperplasia (abnormal thickening of the uterine lining) in postmenopausal women with a uterus who are taking estrogen, and to treat secondary amenorrhea (missed periods not caused by pregnancy). Progesterone injection is indicated for amenorrhea and abnormal uterine bleeding caused by a hormonal imbalance. Crinone vaginal gel is used as part of Assisted Reproductive Technology (ART) for progesterone supplementation or replacement, and Crinone 4% is also indicated for secondary amenorrhea. Vaginal inserts — including Endometrin and other progesterone vaginal insert products — are used to support embryo implantation and early pregnancy as part of an ART treatment program for infertile women.

Wild Daisy has been studied for:

  • Bleeding studied, not established Wild Daisy has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Wild Daisy for bleeding

    Although there has been interest in using oral wild daisy for bleeding, there is insufficient reliable information about the clinical effects of wild daisy for this purpose.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Progesterone on your own; if you are taking Wild Daisy for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Wild Daisy or Progesterone

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Wild Daisy or Progesterone, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Progesterone

This page covers Wild Daisy only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Progesterone page lists 126 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate), Adrafinil (moderate) and African Wild Potato (moderate).

By severity: 2 major · 91 moderate · 33 minor.

From our pharmacist’s overview on the Progesterone page

“Many people take progesterone (Milprosa) to support a pregnancy during fertility treatment or as part of hormone therapy, which is exactly when St. John's wort for mood or a morning glass of grapefruit juice can feel harmless.”

Reviewed by 2 · Jul 18, 2026

Open the Progesterone interaction page

One more smart check

Taking Wild Daisy as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing Wild Daisy, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Wild Daisy. Even though Wild Daisy itself has no known interaction with Progesterone, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Wild Daisy and Progesterone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Wild Daisy
Steady interest

#1,356 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Progesterone
Top half

#722 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Wild Daisy is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Wild Daisy reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Wild Daisy and Progesterone records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Wild Daisy

What is Wild Daisy?

Wild Daisy
  • Bruises and minor wounds
  • Inflammation and swelling
  • Coughs and respiratory complaints
  • Digestive upset
  • Fluid retention ('water pill')
  • Skin conditions

Wild daisy (Bellis perennis) is a traditional European herb used mainly for bruises, minor wounds, and inflammation, but high-quality human evidence for any use is lacking. It is generally considered low-risk when used briefly on the skin, but people allergic to ragweed and related plants should be cautious, and it is best avoided in pregnancy and breastfeeding due to limited safety data.

Bellis perennis · Asteraceae · Flowers and leaves (sometimes the whole flowering plant) · Tea, tincture, topical ointment or cream, homeopathic preparations, dried herb

An interaction check asks whether these two react with each other — it does not ask whether Wild Daisy is a good idea for someone in your situation. Here is what our Wild Daisy record says about it on its own.

Wild Daisy: dosing

There is no established, standardized dose for wild daisy. Because it has not been well studied in people, safe and effective amounts are not known.If you choose to use a product, follow the directions on the label and do not exceed them.

From our Wild Daisy monograph — the full record covers uses, side effects and every documented interaction.

Read the full Wild Daisy monograph & all interactions
Medication

About Progesterone

What Is Progesterone Used For?

Brand name: Milprosa

Progesterone capsules (including Prometrium) are used to prevent endometrial hyperplasia (abnormal thickening of the uterine lining) in postmenopausal women with a uterus who are taking estrogen, and to treat secondary amenorrhea (missed periods not caused by pregnancy).

Progesterone injection is indicated for amenorrhea and abnormal uterine bleeding caused by a hormonal imbalance. Crinone vaginal gel is used as part of Assisted Reproductive Technology (ART) for progesterone supplementation or replacement, and Crinone 4% is also indicated for secondary amenorrhea. Vaginal inserts — including Endometrin and other progesterone vaginal insert products — are used to support embryo implantation and early pregnancy as part of an ART treatment program for infertile women.

Most-Reported Side Effects for Progesterone

From FAERS, the FDA’s public side-effect reporting system (22,803 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Headache 2,094 reports
Fatigue 1,795 reports
Nausea 1,475 reports
Rash 984 reports
Dizziness 941 reports
See full Progesterone drug information
Keep checking

Other Drugs & Wild Daisy

Browse every other medication we’ve checked against Wild Daisy — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Wild Daisy against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Wild Daisy list.

See the full Wild Daisy interactions page
See every supplement checked against Progesterone, ranked by severity
Evidence & sources

Wild Daisy References

The 2 sources that drive our Wild Daisy monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Wild Daisy is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Herbs at a Glance — NIH NCCIH Source
  2. Herbal and Dietary Supplements — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Wild Daisy and Progesterone Together: Common Questions

Is it safe to take Wild Daisy with Progesterone?
We do not list a known interaction between Wild Daisy and Progesterone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Wild Daisy and Progesterone used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Wild Daisy in each. That is a conversation for your prescriber, especially if Progesterone is being adjusted to a target.
Does Progesterone interact with any supplements?
Yes. Progesterone has documented interactions with 126 supplements in our database — Wild Daisy is not one of them. The Progesterone interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Wild Daisy monograph Uses, safety profile, and every drug interaction in one place Progesterone drug information The full plain-English guide to this medication Progesterone supplement interactions Every supplement checked against Progesterone, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Progesterone and Wild Daisy?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.