Drug & supplement interaction

Wild Daisy + Hydroxyurea

Hydroxyurea brand names: Droxia, Hydrea, Siklos, Xromi.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Wild Daisy and Hydroxyurea in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Wild Daisy and Hydroxyurea

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Hydroxyurea and Wild Daisy in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Wild Daisy at all — not against Hydroxyurea, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Wild Daisy safety at a glance

Wild Daisy overall Use caution Limited safety data; allergic reactions are possible, especially in people sensitive to the daisy family.
Pregnancy Avoid Not enough safety information; avoid use during pregnancy.
Breastfeeding Avoid Not enough safety information; avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Hydroxyurea and Wild Daisy? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Hydroxyurea’s Own FDA Label Lists

This is not an interaction — none of it involves Wild Daisy. These are the most notable effects listed in the ADVERSE REACTIONS section of Hydroxyurea’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 6 of them are worth acting on rather than waiting out — marked below.

  • Low magnesium Worth acting on
  • Anemia Worth acting on mentioned in 12.0% of FDA reports for Hydroxyurea
  • A low platelet count Worth acting on
  • Shortness of breath Worth acting on
  • A low white blood cell count Worth acting on
  • A higher chance of infection Worth acting on
  • Changes to your period
  • Dry skin
  • Weight gain
  • Pain in an arm or leg

Showing the 10 most notable of 25 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Hydroxyurea. Read the label on DailyMed › Where a percentage is shown, it is the share of 21,027 voluntary FDA FAERS reports for Hydroxyurea that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wild Daisy’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Wild Daisy side to compare — that is a limit of the record, not a statement that Wild Daisy has no side effects.

From our Q&A

Questions About Wild Daisy or Hydroxyurea

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Wild Daisy or Hydroxyurea, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Hydroxyurea

This page covers Wild Daisy only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Hydroxyurea page lists 18 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 10 minor.

From our pharmacist’s overview on the Hydroxyurea page

“People take hydroxyurea (Droxia, Hydrea, Siklos, Xromi) for serious reasons, most often sickle cell disease or certain blood cancers, and it only works if a steady dose reaches the bloodstream. That is exactly what nearly all 18 supplements listed here can undermine, so this page earns real vigilance rather than a skim.”

Reviewed by 2 · Jul 18, 2026

Open the Hydroxyurea interaction page

One more smart check

Taking Wild Daisy as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing Wild Daisy, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Wild Daisy. Even though Wild Daisy itself has no known interaction with Hydroxyurea, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Wild Daisy and Hydroxyurea Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Wild Daisy
Steady interest

#1,400 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Hydroxyurea
Top 5%

#40 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Wild Daisy is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Wild Daisy reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Wild Daisy and Hydroxyurea records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Wild Daisy

What is Wild Daisy?

Wild Daisy
  • Bruises and minor wounds
  • Inflammation and swelling
  • Coughs and respiratory complaints
  • Digestive upset
  • Fluid retention ('water pill')
  • Skin conditions

Wild daisy (Bellis perennis) is a traditional European herb used mainly for bruises, minor wounds, and inflammation, but high-quality human evidence for any use is lacking. It is generally considered low-risk when used briefly on the skin, but people allergic to ragweed and related plants should be cautious, and it is best avoided in pregnancy and breastfeeding due to limited safety data.

Bellis perennis · Asteraceae · Flowers and leaves (sometimes the whole flowering plant) · Tea, tincture, topical ointment or cream, homeopathic preparations, dried herb

An interaction check asks whether these two react with each other — it does not ask whether Wild Daisy is a good idea for someone in your situation. Here is what our Wild Daisy record says about it on its own.

Wild Daisy: dosing

There is no established, standardized dose for wild daisy. Because it has not been well studied in people, safe and effective amounts are not known.If you choose to use a product, follow the directions on the label and do not exceed them.

From our Wild Daisy monograph — the full record covers uses, side effects and every documented interaction.

Read the full Wild Daisy monograph & all interactions
Medication

About Hydroxyurea

What Is Hydroxyurea Used For?

Brand names: Droxia, Hydrea, Siklos, Xromi

Hydroxyurea is used for several serious conditions. Droxia, Siklos, and Xromi are each indicated to reduce the frequency of painful crises and reduce the need for blood transfusions in patients with sickle cell anemia who have recurrent moderate to severe painful crises. Siklos is approved for adults and children 2 years and older; Xromi is approved for children 6 months and older; Droxia is approved for adults.

Hydrea capsules and Hydroxyurea capsules are indicated for resistant chronic myeloid leukemia and for locally advanced squamous cell carcinomas of the head and neck (excluding the lip) when used together with chemoradiation.

Most-Reported Side Effects for Hydroxyurea

From FAERS, the FDA’s public side-effect reporting system (21,027 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 1,548 reports
Sickle cell anaemia with crisis 1,486 reports
Diarrhea 1,408 reports
Nausea 1,306 reports
Headache 1,068 reports
See full Hydroxyurea drug information
Keep checking

Other Drugs & Wild Daisy

Browse every other medication we’ve checked against Wild Daisy — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Wild Daisy against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Wild Daisy list.

See the full Wild Daisy interactions page
See every supplement checked against Hydroxyurea, ranked by severity
Evidence & sources

Wild Daisy References

The 2 sources that drive our Wild Daisy monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Wild Daisy is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Herbs at a Glance — NIH NCCIH Source
  2. Herbal and Dietary Supplements — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Wild Daisy and Hydroxyurea Together: Common Questions

Is it safe to take Wild Daisy with Hydroxyurea?
We do not list a known interaction between Wild Daisy and Hydroxyurea. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Hydroxyurea interact with any supplements?
Yes. Hydroxyurea has documented interactions with 18 supplements in our database — Wild Daisy is not one of them. The Hydroxyurea interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Wild Daisy monograph Uses, safety profile, and every drug interaction in one place Hydroxyurea drug information The full plain-English guide to this medication Hydroxyurea supplement interactions Every supplement checked against Hydroxyurea, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Hydroxyurea and Wild Daisy?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.