Drug & supplement interaction

Winter Savory + Selpercatinib

Selpercatinib brand name: Retevmo.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Winter Savory and Selpercatinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Winter Savory and Selpercatinib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Selpercatinib and Winter Savory in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Winter Savory safety at a glance

Winter Savory overall Use caution Likely safe as a food seasoning, but concentrated extracts and essential oil are not well studied in people.
Pregnancy Avoid Avoid medicinal or essential oil amounts during pregnancy due to a lack of safety data.
Breastfeeding Use caution Food amounts are likely fine, but avoid concentrated supplements and the essential oil without medical advice.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Selpercatinib and Winter Savory? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Selpercatinib

Interactions in our licensed database are recorded against drug classes, not just single drug names. Selpercatinib is filed under 5 classifications — including qt interval-prolonging drugs, cytochrome p450 3a4 (cyp3a4) inhibitors, hepatotoxic drugs. Winter Savory has documented interactions with 1 drug class — the most serious being lithium (moderate) — and none of Selpercatinib’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Winter Savory Does Interact With Other Medications

Winter Savory has 1 moderate known drug interaction in our database — Selpercatinib isn’t one of them. If you take anything else, check it against the full list below.

Moderate 1 No known interaction 2,829 (incl. Selpercatinib)
Taking anything else?

Check Another of Your Medications Against Winter Savory

Covers the 2,830 medications we’ve checked against Winter Savory. Pick one to open its full report.

What to actually watch for

What Selpercatinib’s Own FDA Label Lists

This is not an interaction — none of it involves Winter Savory. These are the most notable effects listed in the ADVERSE REACTIONS section of Selpercatinib’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • A change in thyroid levels Worth acting on
  • A stroke or mini-stroke Worth acting on
  • Bone thinning Worth acting on
  • Low sodium Worth acting on
  • Yellowing of the skin or eyes Worth acting on
  • Heart failure Worth acting on
  • Fainting Worth acting on
  • An irregular heartbeat Worth acting on
  • Raised blood pressure Worth acting on mentioned in 5.3% of FDA reports for Selpercatinib
  • Chest pain Worth acting on

Showing the 10 most notable of 44 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Selpercatinib. Read the label on DailyMed › Where a percentage is shown, it is the share of 1,250 voluntary FDA FAERS reports for Selpercatinib that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Winter Savory’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Winter Savory side to compare — that is a limit of the record, not a statement that Winter Savory has no side effects.

Everything else you take

See Every Supplement That Interacts With Selpercatinib

This page covers Winter Savory only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Selpercatinib page lists 178 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Beer (major) and Cesium (major).

By severity: 11 major · 132 moderate · 35 minor.

From our pharmacist’s overview on the Selpercatinib page

“People facing a RET-driven lung or thyroid cancer often add supplements for strength, sleep, or immune support, and with selpercatinib (Retevmo) that instinct needs a careful check. Eleven of the 178 ingredients here carry a major rating, and the largest cluster affects how the drug is cleared by the CYP3A4 enzyme: St.”

Reviewed by 2 · Jul 18, 2026

Open the Selpercatinib interaction page

One more smart check

Taking Winter Savory as Part of a Dietary Supplement Product? Check It for Interactions

We hold 8 real supplement products containing Winter Savory, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Winter Savory. Even though Winter Savory itself has no known interaction with Selpercatinib, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Winter Savory and Selpercatinib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Winter Savory
Steady interest

#748 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Selpercatinib
Top 25%

#462 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Winter Savory reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Winter Savory and Selpercatinib records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Winter Savory

What is Winter Savory?

  • Digestive upset and gas
  • Sore throat
  • Antimicrobial
  • Cough
  • Seasoning food

Winter savory is a culinary herb in the mint family used mainly to flavor food and, in folk medicine, to ease digestion and sore throats. Solid human research is very limited, so it should not be relied on to treat any health condition. It is generally considered safe in food amounts, but concentrated extracts and the essential oil call for more caution.

Satureja montana · Lamiaceae · Leaves, flowering tops, and essential oil · Culinary herb, tea, dried herb, capsules, essential oil

An interaction check asks whether these two react with each other — it does not ask whether Winter Savory is a good idea for someone in your situation. Here is what our Winter Savory record says about it on its own.

Winter Savory: dosing

There is no established, standardized medicinal dose for winter savory. Most people simply use it as a seasoning in cooking, which is considered the safest way to enjoy it.If you choose a tea, capsule, or essential oil product, follow the directions on the product label and do not exceed the suggested amount. Essential oils are very concentrated and require special handling and dilution.

From our Winter Savory monograph — the full record covers uses, side effects and every documented interaction.

Read the full Winter Savory monograph & all interactions
Medication

About Selpercatinib

What Is Selpercatinib Used For?

Brand name: Retevmo

Selpercatinib treats cancers driven by changes in the RET gene — either a gene fusion (where RET joins abnormally with another gene) or a RET mutation (a change in the gene itself). Your doctor will confirm one of these changes with an FDA-approved test before prescribing it.

It is approved for adults with RET fusion-positive non-small cell lung cancer; adults and children 2 and older with RET-mutant medullary thyroid cancer or RET fusion-positive thyroid cancer; and adults and children 2 and older with other advanced solid tumors that have a RET gene fusion and have not responded to prior treatment.

See full Selpercatinib drug information
Keep checking

Other Drugs & Winter Savory

Browse every other medication we’ve checked against Winter Savory — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
1Moderate
0Minor
2,828No known interaction
1 Moderate 2,828 No interaction
Moderate

1 interaction

No interaction 2,828 drugs checked — show the list

We also checked Winter Savory against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,828 medications checked with no known interaction — see the full Winter Savory list.

See the full Winter Savory interactions page
See every supplement checked against Selpercatinib, ranked by severity
Evidence & sources

Winter Savory References

The 3 references that drive our Winter Savory monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. Sansalone S, Russo GI, Mondaini N, Cantiello F, Antonini G, Cai T. A combination of tryptophan, Satureja montana, Tribulus terrestris, Phyllanthus emblica extracts is able to improve sexual quality of life in patient with premature ejaculation. Arch Ital PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Winter Savory and Selpercatinib Together: Common Questions

Is it safe to take Winter Savory with Selpercatinib?
We do not list a known interaction between Winter Savory and Selpercatinib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Winter Savory and Selpercatinib combination checked?
Interactions in our licensed database are recorded against drug classes. Selpercatinib is filed under 5 classifications, and Winter Savory has documented interactions with 1 drug class — none of Selpercatinib's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Winter Savory interact with any other medications?
Yes. Winter Savory has 1 documented drug interaction in our database — Selpercatinib is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Selpercatinib interact with any supplements?
Yes. Selpercatinib has documented interactions with 178 supplements in our database — Winter Savory is not one of them. The Selpercatinib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Winter Savory monograph Uses, safety profile, and every drug interaction in one place Selpercatinib drug information The full plain-English guide to this medication Selpercatinib supplement interactions Every supplement checked against Selpercatinib, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Selpercatinib and Winter Savory?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.