Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

100% Pure L-Threonine Ingredients & Drug Interactions

by NutraBio

100% Pure L-Threonine label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking 100% Pure L-Threonine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

100% Pure L-Threonine is a dietary supplement by NutraBio with 1 active ingredient. Its ingredients are commonly taken for general amino acid/protein support, muscle and tissue health, immune support.Based on those ingredients, 3 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are L-Threonine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against 100% Pure L-Threonine by NutraBio

Ask about any prescription or over-the-counter medication and we check it for interactions with 100% Pure L-Threonine by NutraBio — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of 100% Pure L-Threonine by NutraBio

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product is pure L-threonine, one essential amino acid that your body uses to build and repair proteins. It's the single active ingredient, with no fillers or other additives.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Threonine product and its label doesn't state a use — see Threonine's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for L-threonine as a supplement is thin. For amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), it appears possibly ineffective.

For multiple sclerosis, familial spastic paraparesis, and spasticity, we don't have enough reliable evidence to say whether it works or not.

The evidence, ingredient by ingredient Threonine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Threonine from food is safe at normal dietary amounts. When you take it as a supplement at higher doses, though, safety hasn't been well studied.

Reported side effects include headache and mild stomach upset — some people also report diarrhea, bloating, or constipation. Threonine hasn't been well studied in pregnancy or breastfeeding supplements, so the safety data advises against supplement use unless a clinician advises otherwise.

Normal dietary amounts are fine.

Side effects, ingredient by ingredient Threonine

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Threonine.
  • The most serious interaction on file is rated Major.
  • For scale: 3 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take an NMDA antagonist, double-check with your pharmacist before using this product — it may reduce how well the medication works.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

If you're considering L-threonine for a neurological condition, talk with your pharmacist or doctor first — the evidence for most uses is either weak or missing. Anyone taking an NMDA antagonist should check with us before starting.

And because high-dose supplement safety isn't well established, it's worth a conversation before you begin.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about 100% Pure L-Threonine, straight from the product label.

Brand NutraBio
Barcode (UPC) 649908242510
Net contents 500 Gram(s); 1.1 lbs
Market status On market
Date entered into DSLD Oct 22, 2015
DSLD ID 51074
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Kosher, No Allergies, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for 100% Pure L-Threonine by NutraBio, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gram(s)
Maximum serving Sizes:
2 Gram(s)
Servings per container
250
UPC/BARCODE
649908242510
IngredientAmount% DV
L-Threonine2000 mg--

Other ingredients: Absolutely None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

1 serving Mixed with 8-16 oz. Favorite Beverage 1-2x daily Suggested Use: As a dietary supplement, add 1 scoop (2 grams) to your favorite beverage 1-2 times daily, or as directed by a physician.

Formulation

VEGETARIAN

ALLERGEN FREE ~ NON-GMO ~ GLUTEN FREE ~ BSE/TSE FREE

ZERO Fillers or Excipients Inferior ingredients Banned substances Added sugars Proprietary Blends Hidden ingredients

No fillers No excipients No additives

Free of Harmful Impurities.

Formula

ALLERGEN FREE

Precautions

Warning: NOT INTENDED FOR USE BY PERSONS UNDER THE AGE OF 18. KEEP OUT OF THE REACH OF CHILDREN.

If you are pregnant, breast feeding, have known medical conditions (including kidney or liver disease) or are taking prescription or OTC medication(s) consult with your health care practitioner before using this product.

General Statements

Manufactured in a GMP & FDA inspected facility

Made in a GMP & FDA inspected facility

Free Form Essential Amino Acid

Pharmaceutical Grade. HPLC Lab Tested for Potency.

Powder

250 servings

SERVING SCOOP INCLUDED (MAY SETTLE TO THE BOTTOM DURING SHIPPING.)

Since 1996

Quality and purity since 1996. NutraBio manufactures in our own FDA registered & inspected GMP facility complying with FDA 21 CFR Part 111 regulations.

Brand IP Statement(s)

Amino Therapy

Seals/Symbols

TRUE LABEL FULL LABEL DISCLOSURE

OU

FDA Statement of Identity

Dietary Supplement

Storage

STORE IN A COOL DRY PLACE.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

24251-006 B20201-001

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

100% Pure L-Threonine by NutraBio label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

100% Pure L-Threonine label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in 100% Pure L-Threonine by NutraBio

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Gram(s) Dosage formPowder Servings per container250 Amounts shown are per serving.

L-Threonine

Interacts with
3 drugs
2000 mg per serving

Threonine is an essential amino acid your body needs but cannot make, so you must get it from food or supplements. Most people get plenty from a norma...

L-Threonine monograph & interactions

Other (inactive) ingredients: Absolutely None. These complete the product’s ingredient list but are not active constituents.

Interaction report

100% Pure L-Threonine by NutraBio Drug Interactions

Want to check YOUR meds against 100% Pure L-Threonine?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
3Drugs
3 Major

Ingredients driving the most interactions

L-Threonine 3

Individual Drug Interactions

The ingredients in 100% Pure L-Threonine interact with 3 drugs. Click any drug to see the details.

1 of the 1 ingredient in 100% Pure L-Threonine interact with drugs. Each result below shows which ingredient is responsible. L-Threonine

Each ingredient & the kinds of drugs it affects

For each ingredient in 100% Pure L-Threonine with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Threonine1 drug type · 3 drugs

Nmda Antagonists

Theoretically, threonine might decrease the effects of NMDA antagonists.
Threonine increases central nervous system (CNS) glycine levels. Glycine seems to bind a site on NMDA receptors and enhance the activity of the receptors.

Likelihood Likely Evidence B
L-Threonine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for 100% Pure L-Threonine, from the product label.

NutraBio

See all NutraBio products
Name
NutraBio Labs, Inc.
Street Address
564 Lincoln Blvd.
City
Middlesex
State
NJ
ZipCode
08846
Phone Number
732-748-8606
Web Address
www.nutrabio.com
Pharmacist Counseling Corner

100% Pure L-Threonine by NutraBio: Common Questions

Does 100% Pure L-Threonine by NutraBio interact with any medications?
Yes. Based on its ingredients, 100% Pure L-Threonine has a known interaction with 3 medications, including 3 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
100% Pure L-Threonine contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is L-threonine, and what is it supposed to do?
L-threonine is an essential amino acid your body needs to build proteins. This supplement is marketed for neurological conditions like ALS, multiple sclerosis, and spasticity, though the evidence that it actually works for these conditions is either weak or not well established.
Can I take this if I'm pregnant or breastfeeding?
The safety data advises against threonine supplements in pregnancy and breastfeeding because they haven't been well studied at supplement doses. Normal dietary amounts are fine. Talk with your doctor or pharmacist for personalized advice.
What side effects might I experience?
Headache and mild gastrointestinal upset are the most commonly reported side effects. Some people also experience diarrhea, bloating, or constipation.
Is this pure threonine with nothing else in it?
Yes — it's 100% pure L-threonine powder with no fillers, binders, or other inactive ingredients.
I take a medication for nerve pain or neurological issues. Is this safe for me?
It depends on your specific medication. If you take an NMDA antagonist, this supplement could reduce how well it works. Use the medication checker on this page or ask your pharmacist to verify your exact medication before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if 100% Pure L-Threonine is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

100% Pure L-Threonine label
Go deeper

The Full Monographs Behind 100% Pure L-Threonine’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Threonine

Interacts with 3 drugs

Threonine is an essential amino acid your body needs but cannot make, so you must get it from food or supplements. Most people get plenty from a normal diet, and high-quality evidence for ta...

Read the full Threonine monograph →
Sources

Sources & How We Checked

100% Pure L-Threonine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Threonine 4 references
  1. Tandan R, Bromberg MB, Forshew D, et al. A controlled trial of amino acid therapy in amyotrophic lateral sclerosis: I. Clinical, functional, and maximum isometric torque data. Neurology 1996;47:1220-6. PubMed
  2. Lee A, Patterson V. A double blind study of L-threonine in patients with spinal spasticity. Acta Neurol Scand 1993;88:334-8. PubMed
  3. Blin O, Pouget J, Aubrespy G, et al. A double-blind placebo controlled trial of L-threonine in amyotrophic lateral sclerosis. J Neurol 1992;239:79-81.
  4. Roufs JB. L-threonine as a symptomatic treatment for amyotrophic lateral sclerosis (ALS). Med Hypotheses 1991;34:20-3. PubMed

See these in context on the Threonine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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