100% Pure Premium Garcinia Cambogia Ingredients & Drug Interactions
by Vitals
What is this page for?
First and foremost: checking 100% Pure Premium Garcinia Cambogia against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
100% Pure Premium Garcinia Cambogia is a dietary supplement by Vitals with 1 active ingredient. Its ingredients are commonly taken for weight loss, appetite suppression, curbing sugar and carb cravings.Based on those ingredients, 704 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Garcinia cambogia extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against 100% Pure Premium Garcinia Cambogia by Vitals
Ask about any prescription or over-the-counter medication and we check it for interactions with 100% Pure Premium Garcinia Cambogia by Vitals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of 100% Pure Premium Garcinia Cambogia by Vitals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: garcinia cambogia extract, the dried fruit from a tropical plant. The extract is standardized to deliver hydroxycitric acid (HCA), its primary active compound, which is thought to work on appetite and metabolism.
The only other ingredient is cellulose, an inactive filler.
Does it work?
Not established
The evidence for garcinia cambogia is limited. Our data shows insufficient reliable evidence to rate it for weight loss (obesity), cholesterol levels (hyperlipidemia), athletic performance, or liver health (nonalcoholic fatty liver disease).
While garcinia is widely marketed for weight control, the science we have on file doesn't yet establish that it actually works for these purposes in people.
How safe is it?
Well-documented data
Garcinia is generally well tolerated short-term, with most people experiencing no problems. The most common side effects are mild—diarrhea, stomach discomfort, headache, and nausea—but they're not universal.
Rarely, garcinia has been linked to liver injury and liver failure, which is why caution is warranted, especially if you have existing liver disease or take medications that stress the liver. There's also a rare case report of acute heart muscle inflammation.
Additionally, garcinia has been linked to mania in a small number of users, particularly those with bipolar disorder; symptoms typically appear 1 to 8 weeks after starting. The safety data during pregnancy and breastfeeding is insufficient; the product should be avoided in both situations.
Meds to double-check
Moderate interaction found
Before taking this product, double-check your medications with your pharmacist, especially if you take serotonergic drugs (antidepressants and anxiety medications), blood thinners or antiplatelet agents, diabetes medications, or drugs known to affect the liver. All four drug types carry moderate interaction risk with garcinia.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
Garcinia cambogia is marketed for weight loss and metabolic support, but the evidence doesn't yet show it works for these claims. More importantly, it interacts with blood thinners, depression and anxiety medications, diabetes drugs, and potentially liver-toxic medications.
If you take any prescription medication—especially serotonergic drugs, anticoagulants, or diabetes treatments—check with your pharmacist before starting this product. Avoid it during pregnancy and breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about 100% Pure Premium Garcinia Cambogia, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for 100% Pure Premium Garcinia Cambogia by Vitals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Garcinia cambogia extract | 750 mg | -- |
Other ingredients: Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement take one (1) veggie capsule twice a day. For best results take 20-30 min before a meal with an 8 oz. glass of water or as directed by your Healthcare Professional.
Precautions
Caution: Do not exceed recommended dose.
Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children.
Do not use if safety seal is damaged or missing.
Storage
Store in a cool, dry place.
Seals/Symbols
Manufactured & Tested in the USA FDA Registered Facility
Made in USA
General Statements
Lot # and Expiration Date printed on bottom of bottle.
Formula
100% Pure Premium Garcinia Cambogia With 80% HCA
FDA Statement of Identity
Dietary Supplement
Formulation
FDA Registered Facility
GMO Free Gluten Free Lactose Free BPA Free
Brand IP Statement(s)
Copyright Vitals All Rights Reserved
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
100% Pure Premium Garcinia Cambogia by Vitals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in 100% Pure Premium Garcinia Cambogia by Vitals
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Garcinia cambogia extract
Interacts with704 drugs
Garcinia is a tropical fruit whose rind contains hydroxycitric acid (HCA), widely marketed for weight loss and appetite control. The scientific eviden...
Garcinia cambogia extract monograph & interactionsOther (inactive) ingredients: Cellulose. These complete the product’s ingredient list but are not active constituents.
100% Pure Premium Garcinia Cambogia by Vitals Drug Interactions
HelloPharmacist Interaction Report
Vitals 100% Pure Premium Garcinia Cambogia contains garcinia cambogia extract, which has documented interactions with several medication types.
The most serious concern involves serotonergic drugs—medications used for depression and anxiety. Combining garcinia with these drugs carries a moderate risk of serotonin syndrome, a potentially serious condition marked by agitation, confusion, rapid heart rate, and muscle rigidity.
One case report documented this happening when garcinia was taken alongside escitalopram.
Read the full breakdown — every affected drug type, severity by severity
Garcinia also interacts moderately with blood thinners and antiplatelet drugs (such as warfarin and aspirin), potentially increasing bleeding risk. The extract may also add to the effect of diabetes medications and raise the risk of low blood sugar (hypoglycemia).
Additionally, there's a moderate theoretical concern that garcinia could increase liver damage when combined with other drugs known to stress the liver.
Altogether, these interactions span 687 individual medications. We strongly recommend checking your exact prescriptions with the search tool on this page before starting garcinia.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against 100% Pure Premium Garcinia Cambogia?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in 100% Pure Premium Garcinia Cambogia interact with 704 drugs. Click any drug to see the details.
1 of the 1 ingredient in 100% Pure Premium Garcinia Cambogia interact with drugs. Each result below shows which ingredient is responsible. Garcinia cambogia extract
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Extract + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Extract + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Extract + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia Cambogia Extract + Abciximab interactionAbiraterone
How Abiraterone interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia Cambogia Extract + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractAntidiabetes Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
Read the full Garcinia Cambogia Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia Cambogia Extract + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractAnticoagulant/antiplatelet Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia Cambogia Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractHepatotoxic Drugs, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractHepatotoxic Drugs, Serotonergic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia Cambogia Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia Cambogia Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractHepatotoxic Drugs, Serotonergic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with 100% Pure Premium Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia ExtractSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia Cambogia Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in 100% Pure Premium Garcinia Cambogia with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Garcinia cambogia extract
Anticoagulant/Antiplatelet Drugs
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
HCA inhibits platelet aggregation in vitro. The inhibitory effect seems to be greater in platelets extracted from diabetic subjects than non-diabetic subjects.
Antidiabetes Drugs
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
HCA reduces fasting and postprandial blood glucose levels in animal models, theoretically by delaying glucose absorption. This effect has not been reported in humans.
Hepatotoxic Drugs
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
There have been reports of acute hepatitis with elevated liver enzymes associated with garcinia, when taken alone or in combination with other ingredients. Case reports collected from the Drug Induced Liver Injury Network suggest this risk may be greater in people who carry the HLA B*35:01 allele.
Serotonergic Drugs
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
In one report, a patient experienced serotonin syndrome after taking garcinia extract (60% hydroxycitric acid) 1000 mg daily in combination with escitalopram 20 mg, which had been taken for a year. The patient was switched to sertraline 50 mg daily and again experienced serotonin syndrome.
Brand information
Manufacturer and brand details for 100% Pure Premium Garcinia Cambogia, from the product label.
Vitals
See all Vitals products- Name
- Vitals
- Street Address
- 5647 W. Wells Park Rd
- City
- West Jordan
- State
- UT
- ZipCode
- 84081
- Phone Number
- +1 (628) 201-0240
- Web Address
- vitals-health.com
100% Pure Premium Garcinia Cambogia by Vitals: Common Questions
Does 100% Pure Premium Garcinia Cambogia by Vitals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does garcinia cambogia actually help with weight loss?
What are the most common side effects?
Is garcinia safe during pregnancy or while breastfeeding?
Can garcinia damage my liver?
What's in this product besides garcinia?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if 100% Pure Premium Garcinia Cambogia is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind 100% Pure Premium Garcinia Cambogia’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
100% Pure Premium Garcinia Cambogia's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 44 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Garcinia 44 references
- Heymsfield SB, Allison DB, Vasselli JR, et al. Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent: a randomized controlled trial. JAMA 1998;280:1596-600. PubMed
- Soni MG, Burdock GA, Preuss HG, et al. Safety assessment of (-)-hydroxycitric acid and Super CitriMax, a novel calcium/potassium salt. Food Chem Toxicol 2004;42:1513-29. PubMed
- Stevens T, Qadri A, Zein NN. Two patients with acute liver injury associated with use of the herbal weight-loss supplement hydroxycut. Ann Intern Med 2005;142:477-8. PubMed
- Willis SL, Moawad FJ, Hartzell JD, et al. Hypertensive retinopathy associated with use of the ephedra-free weight-loss herbal supplement Hydroxycut. MedGenMed 2006;8:82.
- Preuss HG, Bagchi D, Bagchi M, et al. Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight loss. Diabetes Obes Metab 2004;6:171-180.
- Mansi IA, Huang J. Rhabdomyolysis in response to weight-loss herbal medicine. Am J Med Sci 2004;327:356-357. PubMed
- Lopez AM, Kornegay J, Hendrickson RG. Serotonin Toxicity Associated with Garcinia cambogia Over-the-counter Supplement. J Med Toxicol. 2014 Apr 4. [Epub ahead of print]. PubMed
- Michno A, Skibowska A, Raszeja-Specht A, Cwikowska J, Szutowicz A. The role of adenosine triphosphate citrate lyase in the metabolism of acetyl coenzyme a and function of blood platelets in diabetes mellitus. Metabolism 2004;53(1):66-72. PubMed
- Asghar M, Monjok E, Kouamou G, et al. Super CitriMax (HCA-SX) attenuates increases in oxidative stress, inflammation, insulin resistance, and body weight in developing obese Zucker rats. Mol Cell Biochem 2007;304(1-2):93-99. PubMed
- Wielinga PY, Wachters-Hagedoorn RE, Bouter B, et al. Hydroxycitric acid delays intestinal glucose absorption in rats. Am J Physiol Gastrointest Liver Physiol 2005;288(6):G1144-G1149. PubMed
- Leonhardt M, Balkan B, Langhans W. Effect of hydroxycitrate on respiratory quotient, energy expenditure, and glucose tolerance in male rats after a period of restrictive feeding. Nutrition 2004;20(10):911-915. PubMed
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