Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

12-Hour Energy Caps Ingredients & Drug Interactions

by Terry Naturally

12-Hour Energy Caps label
See full label image
Softgel Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking 12-Hour Energy Caps against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

12-Hour Energy Caps is a dietary supplement by Terry Naturally with 3 active ingredients. Its ingredients are commonly taken for cough and respiratory congestion, sore throat, digestive upset.Based on those ingredients, 379 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Thyme. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against 12-Hour Energy Caps by Terry Naturally

Ask about any prescription or over-the-counter medication and we check it for interactions with 12-Hour Energy Caps by Terry Naturally — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of 12-Hour Energy Caps by Terry Naturally

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Proprietary Formula” is a proprietary blend — the label gives one combined amount (125 mg) without saying how much of each component you get.

This product has 3 active ingredients: thyme, Scots Pine, and Black Spruce. The thyme is part of a proprietary formula, so we can't break down its exact dose.

These plant extracts are suspended in a softgel made with extra virgin olive oil, gelatin, glycerin, and water.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Thyme's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: sustained energy and mental physical sexual health.
  • We looked for evidence on: Cough, Bronchitis, Common cold, Laryngitis, Dyspepsia, fatigue — and 3 related terms.
  • The closest evidence on file: Thyme is rated "Insufficient Reliable Evidence To Rate" for Bronchitis (Natural Medicines).
  • Also on file: Thyme is rated "Insufficient Reliable Evidence To Rate" for Common cold, Cough, Dyspepsia, Laryngitis.

The evidence for thyme in this product isn't established yet. Our data shows insufficient reliable evidence to rate its use for bronchitis, common cold, aging skin, or alopecia areata (hair loss condition).

If you're looking for help with one of those issues, talk to your pharmacist about what the science actually supports.

The evidence, ingredient by ingredient Thyme

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Thyme in food amounts — the kind you'd use in cooking — is generally safe. Medicinal or concentrated doses are a different story, and the concentrated essential oil can be toxic if swallowed, so stick to what's in the capsule and don't add more on your own.

Orally, thyme seems well tolerated when used in medicine. A small number of people report allergic reactions, diarrhea, dizziness, headache, heartburn, nausea, or vomiting.

If any of those show up, stop and call us. Pregnancy and lactation data suggest it's likely safe, but medicinal amounts haven't been well studied — talk with your OB or midwife if you're pregnant or nursing and want to use this.

Side effects, ingredient by ingredient Thyme

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Thyme.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 379 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before starting if you take blood thinners or antiplatelet drugs (Moderate interaction), estrogen replacement therapy (Moderate), anticholinergic drugs like oxybutynin (Moderate), or cholinergic drugs like donepezil (Moderate). For the other medications thyme may affect, your pharmacist can search them on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product is for people looking for an energy boost from plant extracts. If you take a blood thinner, estrogen therapy, or drugs for bladder or nerve conditions, check with your pharmacist first.

We couldn't verify safety data for two of the three ingredients, so definitely talk it over before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 25, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about 12-Hour Energy Caps, straight from the product label.

Brand Terry Naturally
Net contents 30 Softgel(s)
Market status On market
Date entered into DSLD Nov 25, 2014
DSLD ID 39334
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for 12-Hour Energy Caps by Terry Naturally, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
30
IngredientAmount% DV
Proprietary Formula125 mg--
Scots Pine0 NP--
Black Spruce0 NP--
Thyme0 NP--

Other ingredients: extra virgin Olive Oil, Gelatin, Glycerin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

100% PURE BIO-TYPED PLANT OIL SOFTGELS

Safely and naturally provides a sustained level of energy, and contributes to improved mental, physical, and sexual health and well-being. In a product use study, participants with average to low levels of daily energy reported a 111% improvement. Their scores more than doubled after two weeks of use, though most participants reported increased energy after the first day of use.*

Not a stimulant. Will not cause jitters.

Bio-Typed Plant Oils are 75 to 100 times more concentrated than herbal extracts. UNCONDITIONALLY GUARANTEED

Bio-Typed Plant Oils

For Your Good Health

{signature} Terry

Product of Belgium

Formulation

No caffeine. No sugar.

Contains no sugar, salt, yeast, wheat, gluten, corn, soy, dairy products, artificial coloring, artificial flavoring, or preservatives.

FDA Disclaimer Statement

* THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE.

General

JC 34 91 + 3(5,6)EP L40103.07

Seals/Symbols

Terry Naturally(R)

EuroPharma(R)

FDA Statement of Identity

DIETARY SUPPLEMENT

Suggested/Recommended/Usage/Directions

Recommendations: 1 softgel daily. May increase to 2 daily, if needed.

Precautions

If pregnant or nursing, consult a healthcare practitioner before using.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

12-Hour Energy Caps by Terry Naturally label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

12-Hour Energy Caps label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in 12-Hour Energy Caps by Terry Naturally

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Formula

125 mg per serving
  • › Scots Pine
  • › Black Spruce
  • › Thyme

Other (inactive) ingredients: Extra virgin Olive Oil, Gelatin, Glycerin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

12-Hour Energy Caps by Terry Naturally Drug Interactions

Want to check YOUR meds against 12-Hour Energy Caps?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
379Drugs
379 Moderate

Ingredients driving the most interactions

Thyme 379

Individual Drug Interactions

The ingredients in 12-Hour Energy Caps interact with 379 drugs. Click any drug to see the details.

1 of the 3 ingredients in 12-Hour Energy Caps interact with drugs. Each result below shows which ingredient is responsible. Thyme

Each ingredient & the kinds of drugs it affects

For each ingredient in 12-Hour Energy Caps with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Thyme4 drug types · 379 drugs

Anticholinergic Drugs

Theoretically, concurrent use of anticholinergic drugs and thyme essential oil might reduce the effects of anticholinergic drugs.
In vitro evidence suggests that thyme essential oil and specific essential oil constituents like thymohydroquinone and carvacrol can inhibit acetylcholinesterase (AChE). However, this effect has not been observed in humans.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, thyme leaf extract might have additive effects with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that thyme leaf extract has antiplatelet effects. However, this effect has not been observed in humans.

Likelihood Possible Evidence D
Cholinergic Drugs

Theoretically, concurrent use of cholinergic drugs and thyme essential oil might cause additive cholinergic effects.
In vitro evidence suggests that thyme essential oil and specific essential oil constituents like thymohydroquinone and carvacrol can inhibit acetylcholinesterase (AChE). However, this effect has not been observed in humans.

Likelihood Possible Evidence D
Estrogens

Theoretically, thyme might competitively inhibit the effects of estrogen replacement therapy.
In vitro research shows that thyme has estrogen receptor-binding activity and phytoestrogen content. However, this effect has not been observed in humans.

Likelihood Possible Evidence D
Thyme full monograph & interactions
The maker

Brand information

Manufacturer and brand details for 12-Hour Energy Caps, from the product label.

Terry Naturally

See all Terry Naturally products
Name
EuroPharma, Inc.
City
Green Bay
State
WI
ZipCode
54311
Phone Number
(866) 807-2731
Web Address
www.EuroPharmaUSA.com
Pharmacist Counseling Corner

12-Hour Energy Caps by Terry Naturally: Common Questions

Does 12-Hour Energy Caps by Terry Naturally interact with any medications?
Yes. Based on its ingredients, 12-Hour Energy Caps has a known interaction with 379 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
12-Hour Energy Caps contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is thyme safe to take if I'm pregnant or breastfeeding?
The safety data we have rates thyme as likely safe in pregnancy and lactation. That said, medicinal doses haven't been studied a lot, so talk with your OB or midwife before starting — they know your full picture.
What are the side effects I should watch for?
Most people tolerate thyme well. A small number report dizziness, headache, nausea, heartburn, diarrhea, or allergic reactions when taken by mouth. Stop and call us if any of those happen.
Does this product actually work for energy?
The evidence for thyme as an energy booster isn't established in our data. We don't have reliable evidence to rate it for that use — if energy support is your main goal, your pharmacist can discuss what actually has backing.
What's in the capsule besides the active ingredients?
The softgel also contains extra virgin olive oil, gelatin, glycerin, and water — those are the inactive ingredients that hold it together and keep it stable.
Can I check if this interacts with my specific medications?
Yes — use the medication checker on this page and search each drug you take. Thyme interacts with blood thinners, estrogen therapy, and certain nerve and bladder drugs, but the full list is long, so it's best to run your exact meds through the tool.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if 12-Hour Energy Caps is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

12-Hour Energy Caps label
Go deeper

The Full Monographs Behind 12-Hour Energy Caps’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Thyme

Interacts with 379 drugs

Thyme is a common kitchen herb that has long been used for coughs, sore throats, and digestive complaints. It is generally safe in the amounts found in food, and some cough products that com...

Read the full Thyme monograph →
Sources

Sources & How We Checked

12-Hour Energy Caps's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 18 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Thyme 18 references
  1. Zava DT, Dollbaum CM, Blen M. Estrogen and progestin bioactivity of foods, herbs, and spices. Proc Soc Exp Biol Med 1998;217:369-78. PubMed
  2. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  3. Okazaki K, Kawazoe K, Takaishi Y. Human platelet aggregation inhibitors from thyme (Thymus vulgaris L.). Phytother Res 2002;16:398-9. .
  4. Spiewak R, Skorska C, Dutkiewicz J. Occupational airborne contact dermatitis caused by thyme dust. Contact Dermatitis 2001;44:235-9. . PubMed
  5. Ernst E, Marz R, Sieder C. A controlled multi-centre study of herbal versus synthetic secretolytic drugs for acute bronchitis. Phytomedicine 1997;4:287-93. PubMed
  6. Yamamoto J, Yamada K, Naemura A, et al. Testing various herbs for antithrombotic effect. Nutrition 2005;21(5):580-7. PubMed
  7. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  8. Mackiewicz, B., Skorska, C., Dutkiewicz, J., Michnar, M., Milanowski, J., Prazmo, Z., Krysinska-Traczyk, E., and Cisak, E. Allergic alveolitis due to herb dust exposure. Ann Agric Environ Med 1999;6(2):167-170.
  9. Martinez-Gonzalez, M. C., Goday Bujan, J. J., Martinez, Gomez W., and Fonseca, Capdevila E. Concomitant allergic contact dermatitis due to Rosmarinus officinalis (rosemary) and Thymus vulgaris (thyme). Contact Dermatitis 2007;56(1):49-50.
  10. Jukic, M., Politeo, O., Maksimovic, M., Milos, M., and Milos, M. In vitro acetylcholinesterase inhibitory properties of thymol, carvacrol and their derivatives thymoquinone and thymohydroquinone. Phytother.Res 2007;21(3):259-261.
  11. Marzian, O. [Treatment of acute bronchitis in children and adolescents. Non-interventional postmarketing surveillance study confirms the benefit and safety of a syrup made of extracts from thyme and ivy leaves]. MMW.Fortschr.Med 6-28-2007;149(27-28 Suppl
  12. Cuzzolin, L. and Benoni, G. Attitudes and knowledge toward natural products safety in the pharmacy setting: an Italian study. Phytother.Res 2009;23(7):1018-1023. PubMed
  13. Berova, N., Stransky, L., and Krasteva, M. Studies on contact dermatitis in stomatological staff. Dermatol.Monatsschr. 1990;176(1):15-18.
  14. Smeenk, G., Kerckhoffs, H. P., and Schreurs, P. H. Contact allergy to a reaction product in Hirudoid cream: an example of compound allergy. Br.J Dermatol. 1987;116(2):223-231.
  15. Le Roy, R., Grosshans, E., and Foussereau, J. [Investigation of contact allergies in 100 cases of ulcus cruris (author's transl)]. Derm.Beruf.Umwelt. 1981;29(6):168-170.
  16. Lorenzi, S., Placucci, F., Vincenzi, C., Bardazzi, F., and Tosti, A. Allergic contact dermatitis due to thymol. Contact Dermatitis 1995;33(6):439-440. PubMed
  17. Bahadoran P, Rokni FK, Fahami F. Investigating the therapeutic effect of vaginal cream containing garlic and thyme compared to clotrimazole cream for the treatment of mycotic vaginitis. Iran J Nurs Midwifery Res 2010;15(Suppl 1):343-9.
  18. Erol S, Aydin B, Dilli D, Okumus N, Zenciroglu A, Gündüz M. An interesting newborn case of fructose 1-6 diphosphatase deficiency triggered after thyme juice ingestion. Clin Lab. 2014;60(1):151-3. PubMed

See these in context on the Thyme monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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