5-HTP Gold 100 mg Ingredients & Drug Interactions
by NutriGold
What is this page for?
First and foremost: checking 5-HTP Gold 100 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
5-HTP Gold 100 mg is a dietary supplement by NutriGold with 2 active ingredients. Its ingredients are commonly taken for low mood or depression, anxiety and stress, sleep problems.Based on those ingredients, 665 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are 5-HTP, organic Seabuckthorn. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against 5-HTP Gold 100 mg by NutriGold
Ask about any prescription or over-the-counter medication and we check it for interactions with 5-HTP Gold 100 mg by NutriGold — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of 5-HTP Gold 100 mg by NutriGold
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
5-HTP Gold contains two active ingredients: 5-HTP, an amino acid your body naturally makes and uses to produce serotonin (a chemical messenger in your brain), and organic seabuckthorn, a berry fruit extract. The capsule itself and rice concentrate are inactive ingredients — they're just there to hold and deliver the actives.
Does it work?
Moderate evidence
For 5-HTP, the evidence is limited. It's rated possibly effective for depression, but the data we hold shows it's not reliable for down syndrome and we don't have enough good evidence yet for Alzheimer's disease, panic disorder, or cerebellar ataxia (a movement disorder).
For seabuckthorn, the picture is mixed: it's possibly effective for burns, but possibly ineffective for eczema. We don't have enough solid evidence on its use for high cholesterol, aging skin, or cancer.
How safe is it?
Well-documented data
5-HTP is generally well tolerated in the short term, but side effects are common and dose-dependent. Most people who take it experience some stomach upset — nausea, vomiting, abdominal pain, diarrhea — along with dizziness, drowsiness, headache, or loss of appetite.
These may ease with time. Rarely, it's been linked to aggression, hallucinations, and mania, especially at high doses or with carbidopa.
Seabuckthorn at food amounts is generally safe, but supplement safety isn't fully studied. High doses can stain your skin yellow.
The safety data for both ingredients during pregnancy and breastfeeding is too limited — the facts advise against use in both situations. Talk to your pharmacist or doctor before taking this if you're pregnant, trying to conceive, or nursing.
Meds to double-check
Moderate interaction found
Check before taking this product if you use antidepressants, serotonergic pain relievers (tramadol), migraine drugs (triptans), blood thinners (warfarin, dabigatran), antiplatelet drugs (aspirin, clopidogrel), blood pressure medications, sleep aids, or carbidopa. The serotonergic drug interactions are the most serious.
Use the checker on this page to look up your specific medications.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
5-HTP Gold may help if you're dealing with depression, but it's not a first-choice for most people because the evidence is modest and side effects are common. It's not suitable if you take antidepressants, certain pain drugs, migraine medications, sleep aids, or blood thinners — check your medications first.
Talk to your pharmacist before starting, especially if you're on any serotonergic medication or have a history of mania or hallucinations.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about 5-HTP Gold 100 mg, straight from the product label.
| Brand | NutriGold |
|---|---|
| Barcode (UPC) | 859447002203 |
| Net contents | 120 Vegan Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Apr 23, 2020 |
| DSLD ID | 218336 |
| Product type | Botanical With Nutrients |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for 5-HTP Gold 100 mg by NutriGold, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| 5-HTP | 100 mg | -- |
| organic Seabuckthorn | 250 mg | -- |
Other ingredients: Vegan capsule, organic Rice concentrate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Non-GMO verified Griffonia seeds extract standardized to 5-HTP and synergistically formulated with organic seabuckthorn leaf to support emotional wellness.
Health benefits: Supports positive mood, appetite control, and overall emotional wellness.
Verified free of corn, egg, gluten, milk, peanut, shellfish, and soy allergens by an independent lab. No magnesium stearate, stearic acid, dioxides, sulfates, artificial ingredients, or preservatives.
Free of Peak-X
Non-habit forming
Certified Vegan vegan.org
Formula
Non-GMO verified Griffonia seeds extract standardized to 5-HTP and synergistically formulated with organic seabuckthorn leaf to support emotional wellness.
Ko Kosher Service
General Statements
To learn more about this product, scan QR code or visit nutrigold.com/item/220
FDA Statement of Identity
Herbal Supplement
Seals/Symbols
Non GMO Project Verified nongmoproject.org
Certified Vegan vegan.org
Ko Kosher Service
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, adults take one (1) capsule daily, preferably on an empty stomach at bedtime, or as directed by a healthcare professional.
Precautions
Caution: Please consult a healthcare professional before taking this supplement if you are pregnant, breastfeeding, or taking any medications, especially MAO inhibitors, SSRIs, or other anti-depressants.
This product may cause drowsiness.
Keep out of reach of children.
Storage
Store in original container away from moisture and direct sunlight.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
5-HTP Gold 100 mg by NutriGold label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in 5-HTP Gold 100 mg by NutriGold
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
5-HTP
Interacts with398 drugs
5-HTP is a compound your body uses to make serotonin, and people take it as a supplement hoping to improve mood, sleep, and headaches. Some early rese...
5-HTP monograph & interactionsOrganic Seabuckthorn
Interacts with289 drugs
Sea buckthorn is a berry-bearing shrub rich in vitamins, carotenoids, and fatty acids that people use for skin, eye, digestive, and heart health. Earl...
Organic Seabuckthorn monograph & interactionsOther (inactive) ingredients: Vegan capsule, Organic Rice concentrate. These complete the product’s ingredient list but are not active constituents.
5-HTP Gold 100 mg by NutriGold Drug Interactions
HelloPharmacist Interaction Report
5-HTP Gold by NutriGold contains two active ingredients that do interact with medications.
The most serious concern is 5-HTP with serotonergic drugs (antidepressants, some pain relievers, migraine medications) — combining them raises the risk of serotonin syndrome, a potentially serious condition where serotonin levels climb too high. This is a Moderate severity interaction.
Read the full breakdown — every affected drug type, severity by severity
5-HTP also has Moderate interactions with sedating medications (sleep aids, anxiety drugs, opioids, alcohol) — it can add to their drowsy effects — and with carbidopa, a Parkinson's medication, which increases the risk of serotonergic side effects like restlessness, anxiety, and in rare cases, mania or hallucinations.
The seabuckthorn in this product interacts with blood thinners (anticoagulants) and blood-clotting-prevention drugs (antiplatelets like aspirin) at Moderate severity, as it may boost bleeding risk. It also theoretically lowers blood pressure, so combining it with blood pressure medications could drop your pressure too far.
Altogether, these interactions span 663 individual medications. Use the medication checker on this page to look up your exact drugs before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against 5-HTP Gold 100 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in 5-HTP Gold 100 mg interact with 665 drugs. Click any drug to see the details.
2 of the 2 ingredients in 5-HTP Gold 100 mg interact with drugs. Each result below shows which ingredient is responsible. 5-HTP organic Seabuckthorn
AbciximabReoPro
How Abciximab interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SeabuckthornAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sea buckthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic Seabuckthorn + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SeabuckthornAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sea buckthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic Seabuckthorn + Abrocitinib interactionAcebutololRhotral, Sectral
How Acebutolol interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SeabuckthornAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking sea buckthorn with antihypertensive drugs might increase the risk of hypotension.
Read the full Organic Seabuckthorn + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SeabuckthornAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sea buckthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic Seabuckthorn + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acepromazine interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SeabuckthornAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sea buckthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic Seabuckthorn + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SeabuckthornAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sea buckthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic Seabuckthorn + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpCns Depressants, Serotonergic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs, Cns Depressants Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpSerotonergic Drugs Moderate
Interaction Summary
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
Read the full 5-htp + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acetaminophen, Chlorzoxazone, Codeine interactionAcetaminophen, CodeineTylenol No.3, Tylenol w/ Codeine
How Acetaminophen, Codeine interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acetaminophen, Codeine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with 5-HTP Gold 100 mg — through 1 ingredient. Tap an ingredient for the detail:
5-htpCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Acetaminophen, Codeine, Doxylamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in 5-HTP Gold 100 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
5-HTP
Carbidopa (Lodosyn)
Combining 5-HTP and carbidopa can increase the risk of serotonergic side effects.
Carbidopa is sometimes used with 5-HTP to minimize peripheral 5-HTP metabolism and boost the amount that reaches the brain. However, this combination might also increase the risk of some side effects including hypomania, restlessness, rapid speech, anxiety, insomnia, and aggressiveness. Combining carbidopa and 5-HTP might also increase the risk of scleroderma-like skin changes due to elevated serotonin levels.
Cns Depressants
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
In clinical trials, 5-HTP has been associated with drowsiness and somnolence.
Serotonergic Drugs
Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
5-HTP can increase serotonin levels and cause serotonergic effects. Theoretically, combining serotonergic drugs with 5-HTP might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders. However, serotonin syndrome with 5-HTP has not yet been reported in humans. Monitor patients for signs of serotonin syndrome and other serotonergic side effects if using 5-HTP with serotonergic drugs.
organic Seabuckthorn
Anticoagulant/Antiplatelet Drugs
Theoretically, sea buckthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Clinical research suggests that sea buckthorn fruit extracts can inhibit platelet aggregation and adhesion to collagen and fibrinogen.
Antihypertensive Drugs
Theoretically, taking sea buckthorn with antihypertensive drugs might increase the risk of hypotension.
Taking sea buckthorn appears to reduce blood pressure in some patients.
Brand information
Manufacturer and brand details for 5-HTP Gold 100 mg, from the product label.
NutriGold
- Name
- NutriGold Inc.
- City
- Orem
- State
- UT
- ZipCode
- 84057
- Phone Number
- 800-476-3542
- Web Address
- www.nutrigold.com
5-HTP Gold 100 mg by NutriGold: Common Questions
Does 5-HTP Gold 100 mg by NutriGold interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does 5-HTP actually do in my body?
Can I take this if I'm on an antidepressant?
What are the most common side effects I might notice?
Is this safe to take while pregnant or breastfeeding?
Does the seabuckthorn in this do anything, or is it just filler?
Can this really help my depression?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if 5-HTP Gold 100 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind 5-HTP Gold 100 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
5-htp
Interacts with 398 drugs5-HTP is a compound your body uses to make serotonin, and people take it as a supplement hoping to improve mood, sleep, and headaches. Some early research is promising, but the overall evide...
Read the full 5-htp monograph → Herb & supplement monographSea Buckthorn
Interacts with 289 drugsSea buckthorn is a berry-bearing shrub rich in vitamins, carotenoids, and fatty acids that people use for skin, eye, digestive, and heart health. Early research is promising for a few uses l...
Read the full Sea Buckthorn monograph →Sources & How We Checked
5-HTP Gold 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 39 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
5-htp 32 references
- Birdsall TC. 5-Hydroxytryptophan: A Clinically-Effective Serotonin Precursor. Altern Med Rev 1998;3:271-80.
- Michelson D, Page SW, Casey R, et al. An eosinophilia-myalgia syndrome related disorder associated with exposure to L-5-hydroxytryptophan. J Rheumatol 1994;21:2261-5.
- Cangiano C, Ceci F, Cancino A, et al. Eating behavior and adherence to dietary prescriptions in obese adult subjects treated with 5-hydroxytryptophan. Am J Clin Nutr 1992;56:863-7. PubMed
- U.S. Food and Drug Administration. Impurities confirmed in dietary supplement 5-hydroxy-L-tryptophan. FDA Talk Paper, August 31, 1998; T98-48.
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