A.Vogel Sage Menopause Tablets Ingredients & Drug Interactions
by Bioforce
What is this page for?
First and foremost: checking A.Vogel Sage Menopause Tablets against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
A.Vogel Sage Menopause Tablets is a dietary supplement by Bioforce with 1 active ingredient. Its ingredients are commonly taken for sore throat and mouth irritation, digestive upset, excessive sweating.Based on those ingredients, 1,296 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sage leaves extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against A.Vogel Sage Menopause Tablets by Bioforce
Ask about any prescription or over-the-counter medication and we check it for interactions with A.Vogel Sage Menopause Tablets by Bioforce — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of A.Vogel Sage Menopause Tablets by Bioforce
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product has one active ingredient: sage leaves extract. Sage has been used traditionally to help with menopausal hot flashes and night sweats.
The tablet also contains two inactive ingredients — microcrystalline cellulose and cottonseed oil — which are fillers and binders that hold the tablet together.
Does it work?
Moderate evidence
The evidence suggests sage extract is possibly effective for menopausal symptoms, which is what this product is intended for. Research also indicates it may be possibly effective for high cholesterol and cognitive function.
However, the strength of evidence for these uses is modest — we're not talking about a proven cure, but rather a supplement with some research backing its traditional use.
How safe is it?
Well-documented data
Orally, sage extract is generally well tolerated in most people. The most common side effects are mild — abdominal pain, nausea, vomiting, diarrhea, dizziness, and agitation.
Serious side effects like seizures are rare and associated with thujone and related compounds in the plant. Because this product is a concentrated extract (not just a food or tea), the safety notes advise caution.
Sage should be avoided during pregnancy because of thujone content; medicinal amounts during breastfeeding may reduce milk supply, so check with your doctor before taking it if you're nursing.
Meds to double-check
Moderate interaction found
Before taking this product, double-check any medications metabolized by your liver (CYP3A4, CYP2D6, CYP2C19, or CYP2C9 substrates — antidepressants, heart rhythm drugs, and many others fall into these categories). Also flag any CNS depressants like sleeping pills or anxiety medications, blood pressure drugs, and anything transported by P-glycoprotein.
Use the checker below with your full medication list.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
If you're looking for help with menopausal symptoms and have no regular medications, this product has reasonable evidence backing its use. But if you take any prescription drugs — especially for your heart, blood pressure, mood, seizures, or blood clotting — you need to check them against the interaction list first.
Talk to your pharmacist before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 25, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about A.Vogel Sage Menopause Tablets, straight from the product label.
| Brand | Bioforce |
|---|---|
| Barcode (UPC) | 364031532603 |
| Net contents | 60 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Nov 25, 2013 |
| DSLD ID | 26432 |
| Product type | Botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Menopause, Seniors/Mature (>50 Years) - Women ONLY |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for A.Vogel Sage Menopause Tablets by Bioforce, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Sage leaves extract | 15 mg | -- |
Other ingredients: Microcrystalline Cellulose, cottonseed oil
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Like Fresh Herbs in a bottle. Organic, Sustainable Cultivation No pesticides, insectides, fungicides or chemical fertilizers used in growing these herbs. Optimal Potency Bioforce uses a unique process – extracting from fresh herbs, not dried. Fresh herbs are harvested at their peak and processed usually within 24 hours before they can dry out. This special extraction process guarantees a maximum of important fresh elements inherent in each herb. Standardized Manufactured according to Swiss Good Manufacturing Practices. Tests before, during and after processing guarantee uniform quality and purity.
Swiss Product
Support for Hot Flashes and Sweats
Sage is known for supporting normal perspiration*. The popularity of this strongly scented herb and the capacity for its leaves to display beads of liquid in hot weather is well documented. Alfred Vogel recommended its value in his writings throughout his life.
Cultivation with a Conscience
Herbal Extract
Best Before: Lot No.:
Making Nature Work
Suggested/Recommended/Usage/Directions
Suggested Use: Adults: 1 tablet twice daily
Precautions
Safety Sealed Bottle. If ring at bottom of cap is missing or broken, do not use!
Keep out of reach of children.
If you are pregnant or nursing, contact your healthcare professional before using.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General
95943.00 121206
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
PRODUCED IN ACCORDANCE WITH SWISS GOOD MANUFACTURING PRACTICES SWISS GMP Standards
Bioforce
Brand IP Statement(s)
(C) 2004, Bioforce AG Switzerland
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
A.Vogel Sage Menopause Tablets by Bioforce label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in A.Vogel Sage Menopause Tablets by Bioforce
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.
Sage leaves extract
Interacts with1,296 drugs
Sage is a common kitchen herb that is generally safe in food amounts and is traditionally used for sore throats, digestion, sweating, and memory. Some...
Sage leaves extract monograph & interactionsOther (inactive) ingredients: Microcrystalline Cellulose, Cottonseed oil. These complete the product’s ingredient list but are not active constituents.
A.Vogel Sage Menopause Tablets by Bioforce Drug Interactions
HelloPharmacist Interaction Report
A.Vogel Sage Menopause Tablets contains a single active ingredient — sage leaves extract — which has documented interactions with multiple medication types.
The most serious concerns involve drugs metabolized by your liver's cytochrome P450 enzymes (CYP3A4, CYP2D6, CYP2C19, and CYP2C9 substrates) and drugs transported by a protein called P-glycoprotein. Sage can theoretically inhibit these pathways, which means it might raise the blood levels and effects of medications that depend on them — potentially making doses too strong.
These are all Moderate severity interactions.
Read the full breakdown — every affected drug type, severity by severity
Additionally, sage may increase the sedative effects of CNS depressants (drugs that slow your brain activity), and it could unpredictably raise or lower the effects of blood pressure medications. Because different types of sage appear to have opposite effects on blood pressure, the direction of change is uncertain.
There's also a theoretical concern that sage might interfere with hormone therapy or estrogen-based contraceptives, though the clinical significance remains unclear.
Alone among the checked ingredients, sage is the one with documented interaction data. Altogether, these interactions span 1,280 individual medications.
Before you start this product, use the medication checker on this page to look up your exact prescriptions — especially anything for heart rhythm, blood pressure, depression, anxiety, blood thinning, or seizure control.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against A.Vogel Sage Menopause Tablets?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in A.Vogel Sage Menopause Tablets interact with 1,296 drugs. Click any drug to see the details.
1 of the 1 ingredient in A.Vogel Sage Menopause Tablets interact with drugs. Each result below shows which ingredient is responsible. Sage leaves extract
AlprazolamNiravam, Xanax
How Alprazolam interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractBenzodiazepines, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, taking sage might increase the sedative and adverse effects of benzodiazepines.
Read the full Sage Leaves Extract + Alprazolam interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractCns Depressants, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, taking sage might increase the sedative and adverse effects of CNS depressants.
Read the full Sage Leaves Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAlvimopanEntereg
How Alvimopan interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, sage might increase levels of drugs transported by P-glycoprotein.
Read the full Sage Leaves Extract + Alvimopan interactionAmantadineGocovri, Osmolex ER, Symmetrel
How Amantadine interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, sage might decrease the clinical effects of anticholinergic drugs.
Read the full Sage Leaves Extract + Amantadine interactionAmbenonium ChlorideMytelase
How Ambenonium Chloride interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractCholinergic Drugs Moderate
Interaction Summary
Theoretically, sage might have additive effects when used with cholinergic drugs.
Read the full Sage Leaves Extract + Ambenonium Chloride interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractP-glycoprotein Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, sage might increase levels of drugs transported by P-glycoprotein.
Read the full Sage Leaves Extract + Ambrisentan interactionAmifampridineRuzurgi
How Amifampridine interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractCholinergic Drugs Moderate
Interaction Summary
Theoretically, sage might have additive effects when used with cholinergic drugs.
Read the full Sage Leaves Extract + Amifampridine interactionAmifampridine PhosphateFirdapse
How Amifampridine Phosphate interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractCholinergic Drugs Moderate
Interaction Summary
Theoretically, sage might have additive effects when used with cholinergic drugs.
Read the full Sage Leaves Extract + Amifampridine Phosphate interactionAmilorideAmilamont, Midamor
How Amiloride interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, sage might increase or decrease the effects of antihypertensive drugs.
Read the full Sage Leaves Extract + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, sage might increase or decrease the effects of antihypertensive drugs.
Read the full Sage Leaves Extract + Amiloride, Hydrochlorothiazide interactionAminoglutethimideCytadren
How Aminoglutethimide interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractAnticholinergic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, sage might decrease the clinical effects of anticholinergic drugs.
Read the full Sage Leaves Extract + Aminoglutethimide interactionAminophylline, Amobarbital, EphedrineAmesec
How Aminophylline, Amobarbital, Ephedrine interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractCns Depressants, Anticonvulsants Moderate
Interaction Summary
Theoretically, taking sage might increase the sedative and adverse effects of CNS depressants.
Read the full Sage Leaves Extract + Aminophylline, Amobarbital, Ephedrine interactionAmiodaroneCordarone, Pacerone
How Amiodarone interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Sage Leaves Extract + Amiodarone interactionAmitriptylineElavil
How Amitriptyline interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants +4 Moderate
Interaction Summary
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Sage Leaves Extract + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractBenzodiazepines, Anticholinergic Drugs +5 Moderate
Interaction Summary
Theoretically, taking sage might increase the sedative and adverse effects of benzodiazepines.
Read the full Sage Leaves Extract + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 2c19 (cyp2c19) Substrates +4 Moderate
Interaction Summary
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2D6.
Read the full Sage Leaves Extract + Amitriptyline, Perphenazine interactionAmlodipineNorliqva
How Amlodipine interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Sage Leaves Extract + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, sage might increase or decrease the effects of antihypertensive drugs.
Read the full Sage Leaves Extract + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, sage might increase or decrease the effects of antihypertensive drugs.
Read the full Sage Leaves Extract + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, sage might increase or decrease the effects of antihypertensive drugs.
Read the full Sage Leaves Extract + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Sage Leaves Extract + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, sage might increase or decrease the effects of antihypertensive drugs.
Read the full Sage Leaves Extract + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, sage might increase or decrease the effects of antihypertensive drugs.
Read the full Sage Leaves Extract + Ammonium Chloride interactionAmobarbitalAmytal
How Amobarbital interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractCns Depressants, Anticonvulsants Moderate
Interaction Summary
Theoretically, taking sage might increase the sedative and adverse effects of CNS depressants.
Read the full Sage Leaves Extract + Amobarbital interactionAmobarbital, Ephedrine SulfateEphedrine & Amytal
How Amobarbital, Ephedrine Sulfate interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractAnticonvulsants, Cns Depressants Moderate
Interaction Summary
Theoretically, sage might interfere with the clinical effects of anticonvulsant drugs.
Read the full Sage Leaves Extract + Amobarbital, Ephedrine Sulfate interactionAmobarbital, SecobarbitalTuinal
How Amobarbital, Secobarbital interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractCns Depressants, Anticonvulsants Moderate
Interaction Summary
Theoretically, taking sage might increase the sedative and adverse effects of CNS depressants.
Read the full Sage Leaves Extract + Amobarbital, Secobarbital interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractCytochrome P450 2c9 (cyp2c9) Substrates, Cytochrome P450 2c19 (cyp2c19) Substrates +1 Moderate
Interaction Summary
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2C9.
Read the full Sage Leaves Extract + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphetamineAdensys XR-ODT, Adzenys ER, Dyanavel XR, Mydayis
How Amphetamine interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2D6.
Read the full Sage Leaves Extract + Amphetamine interactionAmphetamine Aspartate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine SulfateAdderall, Adderall XR
How Amphetamine Aspartate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2D6.
Read the full Sage Leaves Extract + Amphetamine Aspartate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate interactionAmphetamine SulfateBenzedrine, Evekeo ODT
How Amphetamine Sulfate interacts with A.Vogel Sage Menopause Tablets — through 1 ingredient. Tap an ingredient for the detail:
Sage Leaves ExtractCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2D6.
Read the full Sage Leaves Extract + Amphetamine Sulfate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in A.Vogel Sage Menopause Tablets with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Sage leaves extract
Anticholinergic Drugs
Theoretically, sage might decrease the clinical effects of anticholinergic drugs.
In vitro evidence suggests that common sage (Salvia officinalis) and Spanish sage (Salvia lavandulaefolia) can inhibit acetylcholinesterase and might increase acetylcholine levels.
Anticonvulsants
Theoretically, sage might interfere with the clinical effects of anticonvulsant drugs.
Some species of sage can cause convulsions when consumed in large quantities.
Antidiabetes Drugs
Theoretically, taking sage with antidiabetes drugs might increase the risk of hypoglycemia.
In patients with polycystic ovary syndrome (PCOS) or inadequately controlled type 2 diabetes, common sage (Salvia officinalis) has demonstrated hypoglycemic activity. However, other clinical research in patients with inadequately controlled type 2 diabetes shows that common sage extract does not lower fasting blood glucose levels.
Antihypertensive Drugs
Theoretically, sage might increase or decrease the effects of antihypertensive drugs.
Animal research suggests that common sage (Salvia officinalis) can cause prolonged blood pressure reduction. However, clinical research suggests that Spanish sage (Salvia lavandulaefolia) can increase blood pressure in some people with hypertension. Until more is known, use with caution.
Benzodiazepines
Theoretically, taking sage might increase the sedative and adverse effects of benzodiazepines.
In vitro evidence suggests that certain components of common sage (Salvia officinalis) can bind to benzodiazepine receptors. This effect has not been reported in humans.
Cholinergic Drugs
Theoretically, sage might have additive effects when used with cholinergic drugs.
In vitro evidence suggests that common sage (Salvia officinalis) and Spanish sage (Salvia lavandulaefolia) can inhibit acetylcholinesterase and might increase acetylcholine levels.
Cns Depressants
Theoretically, taking sage might increase the sedative and adverse effects of CNS depressants.
Some constituents of sage have CNS depressant activity.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2C19.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP2C19. So far, this interaction has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2C9.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP2C9. So far, this interaction has not been reported in humans.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2D6.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP2D6. So far, this interaction has not been reported in humans.
Cytochrome P450 2E1 (Cyp2E1) Substrates
Theoretically, sage might decrease the levels and clinical effects of drugs metabolized by CYP2E1.
Animal research suggests that drinking common sage (Salvia officinalis) tea increases the expression of CYP2E1. So far, this interaction has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP3A4.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP3A4. So far, this interaction has not been reported in humans.
Estrogens
Theoretically, sage might interfere with hormone therapy.
In vitro evidence suggests that geraniol, a constituent of Spanish sage (Salvia lavandulaefolia), exerts estrogenic activity. The clinical significance of this effect is unclear.
P-Glycoprotein Substrates
Theoretically, sage might increase levels of drugs transported by P-glycoprotein.
In vitro research suggests that common sage (Salvia officinalis) can inhibit the multi-drug transporter protein, P-glycoprotein. This effect has not been reported in humans.
Brand information
Manufacturer and brand details for A.Vogel Sage Menopause Tablets, from the product label.
A.Vogel Sage Menopause Tablets by Bioforce: Common Questions
Does A.Vogel Sage Menopause Tablets by Bioforce interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does sage extract actually help with hot flashes and night sweats?
What are the most common side effects I might experience?
Is it safe to take if I'm pregnant or breastfeeding?
How is this different from just brewing sage tea?
Can this interfere with my birth control?
Is there anything else in this tablet besides sage?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if A.Vogel Sage Menopause Tablets is safe with your meds?
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind A.Vogel Sage Menopause Tablets’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
A.Vogel Sage Menopause Tablets's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 27 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sage 27 references
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Todorov S, Philianos S, Petkov V, et al. Experimental pharmacological study of three species from genus Salvia. Acta Physiol Pharmacol (Bulg) 1984;10:13-20.
- Perry NS, Bollen C, Perry EK, Ballard C. Salvia for dementia therapy: review of pharmacological activity and pilot tolerability clinical trial. Pharmacol Biochem Behav 2003;75:651-9.. PubMed
- Saller R, Buechi S, Meyrat R, Schmidhauser C. Combined herbal preparation for topical treatment of Herpes labialis. Forsch Komplementarmed Klass Naturheilkd 2001;8:373-82. PubMed
- Akhondzadeh S, Noroozian M, Mohammadi M, et al. Salvia officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomized and placebo-controlled trial. J Clin Pharm Ther 2003;28:53-9.
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