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Dietary supplement

A.Vogel Sage Menopause Tablets Ingredients & Drug Interactions

by Bioforce

Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

A.Vogel Sage Menopause Tablets is a dietary supplement by Bioforce with 1 active ingredient. Its ingredients are commonly taken for sore throat and mouth irritation, digestive upset, excessive sweating.Based on those ingredients, 1,296 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sage leaves extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of A.Vogel Sage Menopause Tablets by Bioforce

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product has one active ingredient: sage leaves extract. Sage has been used traditionally to help with menopausal hot flashes and night sweats.

The tablet also contains two inactive ingredients — microcrystalline cellulose and cottonseed oil — which are fillers and binders that hold the tablet together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Support for hot flashes and sweats.
  • We looked for evidence on: Menopausal symptoms, Androgen deprivation therapy (ADT)-associated hot flashes, Night sweats, Vasomotor symptoms.
  • The strongest evidence on file: Sage is rated "Possibly Effective" for Menopausal symptoms (Natural Medicines).
  • Also on file: Sage is rated "Insufficient Reliable Evidence To Rate" for Androgen deprivation therapy (ADT)-associated hot flashes.

The evidence suggests sage extract is possibly effective for menopausal symptoms, which is what this product is intended for. Research also indicates it may be possibly effective for high cholesterol and cognitive function.

However, the strength of evidence for these uses is modest — we're not talking about a proven cure, but rather a supplement with some research backing its traditional use.

The evidence, ingredient by ingredient Sage

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, sage extract is generally well tolerated in most people. The most common side effects are mild — abdominal pain, nausea, vomiting, diarrhea, dizziness, and agitation.

Serious side effects like seizures are rare and associated with thujone and related compounds in the plant. Because this product is a concentrated extract (not just a food or tea), the safety notes advise caution.

Sage should be avoided during pregnancy because of thujone content; medicinal amounts during breastfeeding may reduce milk supply, so check with your doctor before taking it if you're nursing.

Side effects, ingredient by ingredient Sage

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Sage.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications; diabetes medications.
  • For scale: 1,297 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check any medications metabolized by your liver (CYP3A4, CYP2D6, CYP2C19, or CYP2C9 substrates — antidepressants, heart rhythm drugs, and many others fall into these categories). Also flag any CNS depressants like sleeping pills or anxiety medications, blood pressure drugs, and anything transported by P-glycoprotein.

Use the checker below with your full medication list.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're looking for help with menopausal symptoms and have no regular medications, this product has reasonable evidence backing its use. But if you take any prescription drugs — especially for your heart, blood pressure, mood, seizures, or blood clotting — you need to check them against the interaction list first.

Talk to your pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about A.Vogel Sage Menopause Tablets, straight from the product label.

Brand Bioforce
Barcode (UPC) 364031532603
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Nov 25, 2013
DSLD ID 26432
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Menopause, Seniors/Mature (>50 Years) - Women ONLY
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for A.Vogel Sage Menopause Tablets by Bioforce, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
60
UPC/BARCODE
364031532603
IngredientAmount% DV
Sage leaves extract15 mg--

Other ingredients: Microcrystalline Cellulose, cottonseed oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Like Fresh Herbs in a bottle. Organic, Sustainable Cultivation No pesticides, insectides, fungicides or chemical fertilizers used in growing these herbs. Optimal Potency Bioforce uses a unique process – extracting from fresh herbs, not dried. Fresh herbs are harvested at their peak and processed usually within 24 hours before they can dry out. This special extraction process guarantees a maximum of important fresh elements inherent in each herb. Standardized Manufactured according to Swiss Good Manufacturing Practices. Tests before, during and after processing guarantee uniform quality and purity.

Swiss Product

Support for Hot Flashes and Sweats

Sage is known for supporting normal perspiration*. The popularity of this strongly scented herb and the capacity for its leaves to display beads of liquid in hot weather is well documented. Alfred Vogel recommended its value in his writings throughout his life.

Cultivation with a Conscience

Herbal Extract

Best Before: Lot No.:

Making Nature Work

Suggested/Recommended/Usage/Directions

Suggested Use: Adults: 1 tablet twice daily

Precautions

Safety Sealed Bottle. If ring at bottom of cap is missing or broken, do not use!

Keep out of reach of children.

If you are pregnant or nursing, contact your healthcare professional before using.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

95943.00 121206

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

PRODUCED IN ACCORDANCE WITH SWISS GOOD MANUFACTURING PRACTICES SWISS GMP Standards

Bioforce

Brand IP Statement(s)

(C) 2004, Bioforce AG Switzerland

See for yourself

A.Vogel Sage Menopause Tablets by Bioforce label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in A.Vogel Sage Menopause Tablets by Bioforce

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Sage leaves extract

Interacts with
1,296 drugs
15 mg per serving

Sage is a common kitchen herb that is generally safe in food amounts and is traditionally used for sore throats, digestion, sweating, and memory. Some...

Sage leaves extract monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Cottonseed oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

A.Vogel Sage Menopause Tablets by Bioforce Drug Interactions

Want to check YOUR meds against A.Vogel Sage Menopause Tablets?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1,296Drugs
1,296 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in A.Vogel Sage Menopause Tablets with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Sage leaves extract14 drug types · 1,296 drugs

Anticholinergic Drugs

Theoretically, sage might decrease the clinical effects of anticholinergic drugs.
In vitro evidence suggests that common sage (Salvia officinalis) and Spanish sage (Salvia lavandulaefolia) can inhibit acetylcholinesterase and might increase acetylcholine levels.

Likelihood Possible Evidence D
Anticonvulsants

Theoretically, sage might interfere with the clinical effects of anticonvulsant drugs.
Some species of sage can cause convulsions when consumed in large quantities.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking sage with antidiabetes drugs might increase the risk of hypoglycemia.
In patients with polycystic ovary syndrome (PCOS) or inadequately controlled type 2 diabetes, common sage (Salvia officinalis) has demonstrated hypoglycemic activity. However, other clinical research in patients with inadequately controlled type 2 diabetes shows that common sage extract does not lower fasting blood glucose levels.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, sage might increase or decrease the effects of antihypertensive drugs.
Animal research suggests that common sage (Salvia officinalis) can cause prolonged blood pressure reduction. However, clinical research suggests that Spanish sage (Salvia lavandulaefolia) can increase blood pressure in some people with hypertension. Until more is known, use with caution.

Likelihood Possible Evidence D
Benzodiazepines

Theoretically, taking sage might increase the sedative and adverse effects of benzodiazepines.
In vitro evidence suggests that certain components of common sage (Salvia officinalis) can bind to benzodiazepine receptors. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cholinergic Drugs

Theoretically, sage might have additive effects when used with cholinergic drugs.
In vitro evidence suggests that common sage (Salvia officinalis) and Spanish sage (Salvia lavandulaefolia) can inhibit acetylcholinesterase and might increase acetylcholine levels.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking sage might increase the sedative and adverse effects of CNS depressants.
Some constituents of sage have CNS depressant activity.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2C19.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP2C19. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2C9.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP2C9. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2D6.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP2D6. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, sage might decrease the levels and clinical effects of drugs metabolized by CYP2E1.
Animal research suggests that drinking common sage (Salvia officinalis) tea increases the expression of CYP2E1. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP3A4.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP3A4. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Estrogens

Theoretically, sage might interfere with hormone therapy.
In vitro evidence suggests that geraniol, a constituent of Spanish sage (Salvia lavandulaefolia), exerts estrogenic activity. The clinical significance of this effect is unclear.

Likelihood Possible Evidence D
P-Glycoprotein Substrates

Theoretically, sage might increase levels of drugs transported by P-glycoprotein.
In vitro research suggests that common sage (Salvia officinalis) can inhibit the multi-drug transporter protein, P-glycoprotein. This effect has not been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for A.Vogel Sage Menopause Tablets, from the product label.

Bioforce

See all Bioforce products
Name
Bioforce AG
Street Address
CH-9325
City
Roggwil TG
Pharmacist Counseling Corner

A.Vogel Sage Menopause Tablets by Bioforce: Common Questions

Does A.Vogel Sage Menopause Tablets by Bioforce interact with any medications?
Yes. Based on its ingredients, A.Vogel Sage Menopause Tablets has a known interaction with 1,296 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
A.Vogel Sage Menopause Tablets contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does sage extract actually help with hot flashes and night sweats?
Yes — research suggests it's possibly effective for menopausal symptoms, which is what this product is designed for. It's not a guaranteed fix, but there's enough evidence that it's worth considering if you're dealing with menopause.
What are the most common side effects I might experience?
Mild ones: abdominal pain, nausea, vomiting, diarrhea, dizziness, and agitation. Most people tolerate it well, but if your stomach is sensitive, this is something to watch for.
Is it safe to take if I'm pregnant or breastfeeding?
No — the data advises against medicinal amounts during pregnancy because of a compound called thujone. If you're breastfeeding, sage may reduce your milk supply, so check with your doctor first before using a concentrated extract like this.
How is this different from just brewing sage tea?
This is a concentrated extract in tablet form, not just regular sage tea. That concentration is why the safety notes caution that you should be more careful with it than you would with food amounts or a home-brewed cup.
Can this interfere with my birth control?
Possibly — sage extract has compounds that might interfere with estrogen-based contraceptives or hormone therapy, though we don't know how significant that effect is in real life. Mention this product to your doctor or pharmacist if you're on hormonal birth control.
Is there anything else in this tablet besides sage?
Yes, there are two inactive ingredients — microcrystalline cellulose and cottonseed oil — which are fillers that hold the tablet together. The active ingredient doing the work is the sage extract.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

A.Vogel Sage Menopause Tablets label
Go deeper

The Full Monographs Behind A.Vogel Sage Menopause Tablets’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

A.Vogel Sage Menopause Tablets's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 27 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sage 27 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Todorov S, Philianos S, Petkov V, et al. Experimental pharmacological study of three species from genus Salvia. Acta Physiol Pharmacol (Bulg) 1984;10:13-20.
  3. Perry NS, Bollen C, Perry EK, Ballard C. Salvia for dementia therapy: review of pharmacological activity and pilot tolerability clinical trial. Pharmacol Biochem Behav 2003;75:651-9.. PubMed
  4. Saller R, Buechi S, Meyrat R, Schmidhauser C. Combined herbal preparation for topical treatment of Herpes labialis. Forsch Komplementarmed Klass Naturheilkd 2001;8:373-82. PubMed
  5. Akhondzadeh S, Noroozian M, Mohammadi M, et al. Salvia officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomized and placebo-controlled trial. J Clin Pharm Ther 2003;28:53-9.
  6. Perry NB, Anderson RE, Brennan NJ, et al. Essential oils from dalmatian sage (Salvia officinalis l.): variations among individuals, plant parts, seasons, and sites. J Agric Food Chem 1999;47:2048-54..
  7. Foster BC, Vandenhoek S, Hana J, et al. In vitro inhibition of human cytochrome P450-mediated metabolism of marker substrates by natural products. Phytomedicine 2003;10:334-42.. PubMed
  8. Burkhard PR, Burkhardt K, Haenggeli CA, Landis T. Plant-induced seizures: reappearance of an old problem. J Neurol 1999;246:667-70. PubMed
  9. Bommer S, Klein P, Suter A. First time proof of sage's tolerability and efficacy in menopausal women with hot flushes. Adv Ther 2011;28:490-500. PubMed
  10. Hellum BH, Nilsen OG. The in vitro inhibitory potential of trade herbal products on human CYP2D6-mediated metabolism and the influence of ethanol. Basic Clin Pharmacol Toxicol. 2007 Nov;101:350-8.
  11. Orhan, I., Kartal, M., Kan, Y., and Sener, B. Activity of essential oils and individual components against acetyl- and butyrylcholinesterase. Z.Naturforsch.C. 2008;63(7-8):547-553.
  12. Perry, N. S., Houghton, P. J., Theobald, A., Jenner, P., and Perry, E. K. In-vitro inhibition of human erythrocyte acetylcholinesterase by salvia lavandulaefolia essential oil and constituent terpenes. J Pharm Pharmacol 2000;52(7):895-902.
  13. Perry, N. S., Houghton, P. J., Sampson, J., Theobald, A. E., Hart, S., Lis-Balchin, M., Hoult, J. R., Evans, P., Jenner, P., Milligan, S., and Perry, E. K. In-vitro activity of S. lavandulaefolia (Spanish sage) relevant to treatment of Alzheimer's diseas
  14. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  15. Kavvadias, D., Monschein, V., Sand, P., Riederer, P., and Schreier, P. Constituents of sage (Salvia officinalis) with in vitro affinity to human brain benzodiazepine receptor. Planta Med. 2003;69(2):113-117.
  16. Savelev, S. U., Okello, E. J., and Perry, E. K. Butyryl- and acetyl-cholinesterase inhibitory activities in essential oils of Salvia species and their constituents. Phytother Res 2004;18(4):315-324.
  17. Kennedy, D. O., Pace, S., Haskell, C., Okello, E. J., Milne, A., and Scholey, A. B. Effects of cholinesterase inhibiting sage (Salvia officinalis) on mood, anxiety and performance on a psychological stressor battery. Neuropsychopharmacology 2006;31(4):84 PubMed
  18. Hubbert, M., Sievers, H., Lehnfeld, R., and Kehrl, W. Efficacy and tolerability of a spray with Salvia officinalis in the treatment of acute pharyngitis - a randomised, double-blind, placebo-controlled study with adaptive design and interim analysis. Eur
  19. Lima, C. F., Fernandes-Ferreira, M., and Pereira-Wilson, C. Drinking of Salvia officinalis tea increases CCl(4)-induced hepatotoxicity in mice. Food Chem.Toxicol. 2007;45(3):456-464.
  20. Hellum, B. H. and Nilsen, O. G. In vitro inhibition of CYP3A4 metabolism and P-glycoprotein-mediated transport by trade herbal products. Basic Clin Pharmacol Toxicol. 2008;102(5):466-475.
  21. Mayer, E., Gescheidt-Shoshany, H., and Weltfriend, S. Allergic contact dermatitis caused by Salvia officinalis extract. Contact Dermatitis 2011;64(4):237-238. PubMed
  22. Halicioglu, O., Astarcioglu, G., Yaprak, I., and Aydinlioglu, H. Toxicity of Salvia officinalis in a newborn and a child: an alarming report. Pediatr.Neurol. 2011;45(4):259-260. PubMed
  23. Sertoli, A., Fabbri, P., Campolmi, P., and Panconesi, E. Allergic contact dermatitis to Salvia Officinalis, Inula Viscosa and Conyza Bonariensis. Contact Dermatitis 1978;4(5):314-315.
  24. Vandecasteele K, Ost P, Oosterlinck W, et al. Evaluation of the efficacy and safety of Salvia officinalis in controlling hot flashes in prostate cancer patients treated with androgen deprivation. Phytother Res. 2012;26(2):208-13.
  25. Kianbakht S, Dabaghian FH. Improved glycemic control and lipid profile in hyperlipidemic type 2 diabetic patients consuming Salvia officinalis L. leaf extract: a randomized placebo. Controlled clinical trial. Complement Ther Med. 2013;21(5):441-6. PubMed
  26. Amini L, Mojab F, Jahanfar S, Sepidarkish M, Raoofi Z, Maleki-Hajiagha A. Efficacy of Salvia officinalis extract on the prevention of insulin resistance in euglycemic patients with polycystic ovary syndrome: A double-blinded placebo-controlled clinical tr
  27. Behradmanesh S, Derees F, Rafieian-Kopaei M. Effect of Salvia officinalis on diabetic patients. J Renal Inj Prev. 2013;2(2):51-4.

See these in context on the Sage monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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