Major interaction on record — check this product against your medications before combining. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

A.Vogel Cardiaforce Tonic Ingredients & Drug Interactions

by Bioforce

A.Vogel Cardiaforce Tonic label
See full label image
Liquid Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking A.Vogel Cardiaforce Tonic against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

A.Vogel Cardiaforce Tonic is a dietary supplement by Bioforce with 3 active ingredients. Its ingredients are commonly taken for heart failure symptoms, high blood pressure, chest pain (angina).Based on those ingredients, 436 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Lemon Balm, English Hawthorn. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against A.Vogel Cardiaforce Tonic by Bioforce

Ask about any prescription or over-the-counter medication and we check it for interactions with A.Vogel Cardiaforce Tonic by Bioforce — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of A.Vogel Cardiaforce Tonic by Bioforce

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Proprietary Blend extract of” is a proprietary blend — the label gives one combined amount (7.20 Gram(s)) without saying how much of each component you get.

Cardiaforce Tonic contains 2 active ingredients: English Hawthorn and Lemon Balm, both supplied as extracts in a proprietary blend. The product is presented as a liquid with 15% alcohol by volume.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: maintain healthy cardiovascular function and heart circulation.
  • We looked for evidence on: Angina, Arrhythmia, Atherosclerosis, Cardiovascular disease (CVD), Congestive heart failure (CHF), Dyslipidemia — and 4 related terms.
  • The closest evidence on file: Lemon Balm is rated "Insufficient Reliable Evidence To Rate" for Ventricular arrhythmias (Natural Medicines).
  • Also on file: Lemon Balm is rated "Insufficient Reliable Evidence To Rate" for Dyslipidemia, Hypertension.
  • Also on file: Hawthorn is rated "Insufficient Reliable Evidence To Rate" for Angina, Arrhythmia, Atherosclerosis, Cardiovascular disease (CVD).

The evidence for Hawthorn's effectiveness in angina, anxiety, heart arrhythmia, atherosclerosis, cardiovascular disease, and cognitive function is insufficient to rate — we don't have strong enough data to confirm it works for these uses. Lemon Balm shows possibly effective evidence for cold sores and stress, and possibly effective for depression.

The evidence, ingredient by ingredient Hawthorn Lemon Balm

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hawthorn is generally well tolerated in studies, but because it affects the heart, medical supervision is necessary. Serious adverse effects are rare; mild ones like palpitations or circulatory problems have been reported in a small number of people with heart failure.

Not enough safety data exists to use Hawthorn during pregnancy or while breastfeeding — the safety data advises against both. Lemon Balm is generally well tolerated for short-term use in healthy adults, though long-term safety at high doses isn't well studied.

It may cause dizziness or sedation, but these don't appear to occur more often than with placebo. The safety data is not sufficient during pregnancy — talk with your doctor or pharmacist about whether to use it.

Limited safety information exists for breastfeeding, so use caution and discuss it with your doctor or pharmacist.

Side effects, ingredient by ingredient Hawthorn Lemon Balm

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Lemon Balm, Hawthorn.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; heart-rhythm medications.
  • For scale: 436 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Cardiaforce Tonic, check with your doctor or pharmacist if you take nitrates or phosphodiesterase-5 inhibitors (Major severity) — the risk of a dangerous blood pressure drop is significant. Also review any beta-blockers, blood thinners, calcium channel blockers, digoxin, CNS depressants (sedatives or sleep aids), or thyroid hormone replacement therapy (all Moderate severity) — the combination may require adjusting doses or timing.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

Cardiaforce Tonic may interest people managing heart conditions, but because it interacts with several common cardiac medications, blood thinners, and other drug types, you'll want to check your exact prescriptions before starting. Given the cardiac focus, medical supervision is important.

Talk it over with your doctor or pharmacist before adding this to your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about A.Vogel Cardiaforce Tonic, straight from the product label.

Brand Bioforce
Barcode (UPC) 364031534003
Net contents 6.8 fl. Oz.; 200 mL
Market status On market
Date entered into DSLD Nov 25, 2013
DSLD ID 26286
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for A.Vogel Cardiaforce Tonic by Bioforce, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
15 Tbsp, 1 Tablespoon(s)
Maximum serving Sizes:
15 Tbsp, 1 Tablespoon(s)
Servings per container
13
UPC/BARCODE
364031534003
IngredientAmount% DV
Calories25 {Calories}--
Total Carbohydrates3 Gram(s)1%
Sugar3 Gram(s)--
Proprietary Blend extract of7.2 Gram(s)--
English Hawthorn0 NP--
Lemon Balm0 NP--

Other ingredients: Alcohol 15% v/v

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Like Fresh Herbs in a bottle. Exclusive A.Vogel Formula Manufactured according to Swiss Pharmaceutical Manufacturing Practices. Standardized Tests before, during and after processing guarantee uniform quality and purity

Swiss Product

Helps maintain healthy cardiovascular function Helps maintain heart circulation Support strong heart muscle

Bioforce uses a unique process-extracting from fresh herbs, not dried. Fresh herbs are harvested at their prime and usually processed within 24 hours before they can dry out. Special extraction process guarantees a maximum of important fresh elements inherent in each herb.

Cultivation with a Conscience

Best Before: Lot No.:

Making Nature Work

Fresh Herb Extract

Formulation

Contains organically grown herbs Organic cultivation certified by Bio-Suisse

Organically grown from our own herb cultivations by our own expert herbalists.

No pesticides, insecticides, fungicides or chemical fertilizers.

Organically Grown

Suggested/Recommended/Usage/Directions

Suggested Use: Adults: 1 tablespoon in a quarter glass of water after meals and upon retiring Shake well before using.

Precautions

Safety Sealed Bottle. If ring at bottom of cap is missing or broken, do not use!

Keep out of reach of children.

Not recommended for anyone on a restricted alcohol diet, including those with liver disease, epilepsy, alcoholics or pregnant women.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

96759.04 040407

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

SWISS GMP PRODUCTS

Bioforce

Brand IP Statement(s)

(C) 2004, Bioforce AG Switzerland

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

A.Vogel Cardiaforce Tonic by Bioforce label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

A.Vogel Cardiaforce Tonic label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in A.Vogel Cardiaforce Tonic by Bioforce

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size15 Tbsp Dosage formLiquid Servings per container13 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

3 Gram(s) per serving

Proprietary Blend extract of

7.2 Gram(s) per serving

Other (inactive) ingredients: Alcohol 15% v/v. These complete the product’s ingredient list but are not active constituents.

Interaction report

A.Vogel Cardiaforce Tonic by Bioforce Drug Interactions

Want to check YOUR meds against A.Vogel Cardiaforce Tonic?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
436Drugs
14 Major 422 Moderate

Ingredients driving the most interactions

Lemon Balm 264
English Hawthorn 191

Individual Drug Interactions

The ingredients in A.Vogel Cardiaforce Tonic interact with 436 drugs. Click any drug to see the details.

2 of the 3 ingredients in A.Vogel Cardiaforce Tonic interact with drugs. Each result below shows which ingredient is responsible. Lemon Balm English Hawthorn

Each ingredient & the kinds of drugs it affects

For each ingredient in A.Vogel Cardiaforce Tonic with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Lemon Balm2 drug types · 264 drugs

Cns Depressants

Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Lemon balm seems to have CNS depressant activity in animals and in humans.

Likelihood Possible Evidence B
Thyroid Hormone

Theoretically, lemon balm might interfere with thyroid hormone replacement therapy.
In vitro, constituents of lemon balm extract bind to thyroid stimulating hormone (TSH), preventing TSH receptor-binding and leading to the inhibition of TSH-stimulated adenylate cyclase activity. In animals, lemon balm extract has been shown to decrease levels of circulating TSH and inhibit thyroid secretion.

Likelihood Possible Evidence D
Lemon Balm full monograph & interactions

English Hawthorn6 drug types · 191 drugs

Nitrates

Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Some evidence shows that hawthorn might lower blood pressure due to vasodilatory effects.

Likelihood Probable Evidence D
Phosphodiesterase-5 Inhibitors

Theoretically, concomitant use might result in additive vasodilation and hypotension.
Hawthorn might inhibit PDE-5 and cause vasodilation.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research shows that hawthorn can inhibit platelet aggregation. However, its effect in humans is unclear. One observational study shows that patients taking hawthorn shortly before undergoing coronary artery bypass graft (CABG) surgery or valve replacement surgery have a 10% incidence of postoperative bleeding, compared with 1% in those who never consumed hawthorn extract. However, clinical research shows that taking a specific preparation of dried hawthorn leaves and flowers (Crataesor, Soria Natural Lab) 800 mg three times daily for 15 days does not affect platelet aggregation or levels of thromboxane B2, the metabolite of thromboxane A2, in healthy humans.

Likelihood Possible Evidence D
Beta-Blockers

Theoretically, concomitant use might cause additive effects on blood pressure and heart rate.
Some evidence shows that hawthorn might lower blood pressure and heart rate.

Likelihood Possible Evidence D
Calcium Channel Blockers

Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Some evidence shows that hawthorn might lower blood pressure due to vasodilatory effects.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, hawthorn might potentiate the effects and adverse effects of digoxin.
Hawthorn appears to improve cardiac output; however, hawthorn does not appear to affect digoxin pharmacokinetics. Case reports suggest that at least one species of hawthorn root extract (Crataegus mexicana) may produce adverse effects similar to digoxin and can cross-react with digoxin assays, leading to falsely elevated plasma digoxin levels.

Likelihood Possible Evidence D
English Hawthorn full monograph & interactions
The maker

Brand information

Manufacturer and brand details for A.Vogel Cardiaforce Tonic, from the product label.

Bioforce

See all Bioforce products
Name
Bioforce AG
Street Address
CH-9325
City
Roggwil TG
Pharmacist Counseling Corner

A.Vogel Cardiaforce Tonic by Bioforce: Common Questions

Does A.Vogel Cardiaforce Tonic by Bioforce interact with any medications?
Yes. Based on its ingredients, A.Vogel Cardiaforce Tonic has a known interaction with 436 medications, including 14 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
A.Vogel Cardiaforce Tonic contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on heart medications?
That depends on which ones. Hawthorn interacts significantly with nitrates, blood pressure medications, blood thinners, and digoxin. Check your exact prescriptions with your doctor or pharmacist — they can tell you whether this product is safe alongside what you're already taking.
Is this safe during pregnancy?
No. The safety data for both Hawthorn and Lemon Balm advises against use during pregnancy because there isn't enough information to know it's safe. Talk with your doctor or pharmacist if you're pregnant or planning to become pregnant.
Can I breastfeed while taking this?
Hawthorn safety data also advises against breastfeeding use. Lemon Balm has limited safety information — use caution and talk with your doctor or pharmacist before using it while nursing.
What are the side effects I should watch for?
Hawthorn is generally well tolerated, but heart-related effects like palpitations or circulatory problems have been reported rarely, mainly in people with existing heart failure. A very rare serious reaction affecting kidneys is possible. Lemon Balm may cause dizziness or sedation, though these are uncommon.
Does Lemon Balm actually work for stress?
Lemon Balm shows possibly effective evidence for stress. That means some research supports its use, but the evidence isn't strong or complete yet.
What's the alcohol content?
This product is 15% alcohol by volume — about the strength of wine. If you need to avoid alcohol, this may not be the right choice.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if A.Vogel Cardiaforce Tonic is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

A.Vogel Cardiaforce Tonic label
Go deeper

The Full Monographs Behind A.Vogel Cardiaforce Tonic’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Hawthorn

Interacts with 191 drugs

Hawthorn is a plant traditionally used for heart-related complaints, and some studies suggest it may modestly help symptoms of mild heart failure when added to standard care. However, the ev...

Read the full Hawthorn monograph → Herb & supplement monograph

Lemon Balm

Interacts with 264 drugs

Lemon balm is a gentle, lemon-scented mint-family herb traditionally used to ease stress, support sleep, and calm digestion, and topically for cold sores. Early studies are promising but gen...

Read the full Lemon Balm monograph →
Sources

Sources & How We Checked

A.Vogel Cardiaforce Tonic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 37 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hawthorn 25 references
  1. Tauchert M. Efficacy and safety of crataegus extract WS 1442 in comparison with placebo in patients with chronic stable New York Heart Association class-III heart failure. Am Heart J 2002;143:910-5. PubMed
  2. Pittler MH, Schmidt K, Ernst E. Hawthorn extract for treating chronic heart failure: meta-analysis of randomized trials. Am J Med 2003;114:665-74.. PubMed
  3. Chang Q, Zuo Z, Harrison F, Chow MS. Hawthorn. J Clin Pharmacol 2002;42:605-12.
  4. Holubarsch CJ, Colucci WS, Meinertz T, et al. The efficacy and safety of Crataegus extract WS 1442 in patients with heart failure: the SPICE trial. Eur J Heart Fail 2008;10:1255-63. PubMed
  5. Pittler MH, Guo R, and Ernst E. Hawthorn extract for treating chronic heart failure. Cochrane.Database.Syst Rev 2008:CD005312. PubMed
  6. Zick SM, Vautaw BM, Gillespie B, Aaronson KD. Hawthorn Extract Randomized Blinded Chronic Heart Failure (HERB CHF) trial. Eur J Heart Fail. 2009;11:990-99. PubMed
  7. Werner NS, Duschek S, and Schandry R. D-camphor-crataegus berry extract combination increases blood pressure and cognitive functioning in the elderly - a randomized, placebo controlled double blind study. Phytomedicine. 2009;16:1077-82. PubMed
  8. Dalli E, Colomer E, Tormos MC, et al. Crataegus laevigata decreases neutrophil elastase and has hypolipidemic effect: a randomized, double-blind, placebo-controlled trial. Phytomedicine. 6-15-2011;18:769-75. PubMed
  9. Maek-a-nantawat W, Phonrat B, Dhitavat J, et al. Safety and efficacy of CKBM-A01, a Chinese herbal medicine, among asymptomatic HIV patients. Southeast Asian J Trop.Med Public Health 2009;40:494-501.
  10. Asher GN, Viera AJ, Weaver MA, et al. Effect of hawthorn standardized extract on flow mediated dilation in prehypertensive and mildly hypertensive adults: a randomized, controlled cross-over trial. BMC.Complement Altern.Med 2012;12:26. PubMed
  11. Walker AF, Marakis G, Simpson E, et al. Hypotensive effects of hawthorn for patients with diabetes taking prescription drugs: a randomised controlled trial. Br J Gen.Pract 2006;56:437-43.
  12. Daniele C, Mazzanti G, Pittler MH, et al. Adverse-event profile of Crataegus spp.: a systematic review. Drug Saf 2006;29:523-35. PubMed
  13. Tankanow R, Tamer HR, Streetman DS, et al. Interaction study between digoxin and a preparation of hawthorn (Crataegus oxyacantha). J.Clin.Pharmacol. 2003;43:637-42. DOI
  14. Tauchert, M., Gildor, A., and Lipinski, J. [High-dose Crataegus extract WS 1442 in the treatment of NYHA stage II heart failure]. Herz 1999;24(6):465-474.
  15. Horoz, M., Gok, E., Genctoy, G., Ozcan, T., Olmaz, R., Akca, M., Kiykim, A., and Gurses, I. Crataegus orientalis associated multiorgan hypersensitivity reaction and acute renal failure. Intern.Med 2008;47(23):2039-2042. PubMed
  16. Dalli, E., Valles, J., Cosin-Sales, J., Santos, M. T., Moscardo, A., Milara, J., and Sotillo, J. F. Effects of hawthorn (Crataegus laevigata) on platelet aggregation in healthy volunteers. Thromb.Res 2011;128(4):398-400. PubMed
  17. Rogov VD. [Toxiderma due to the fruits of the hawthorn]. Vestn Dermatol Venerol 1984;7(7):46-47.
  18. Loew D, Albrecht M, and Podzuweit H. Efficacy and tolerability of a Hawthorn preparation in patients with heart failure Stage I and II according to NYHA - a surveillance study. Phytomedicine 1996;3(Suppl 1):92.
  19. Rababa'h AM, Altarabsheh SE, Haddad O, Deo SV, Obeidat Y, Al-Azzam S. Hawthorn Herb Increases the Risk of Bleeding after Cardiac Surgery: An Evidence-Based Approach. Heart Surg Forum 2016;19(4):E175-9. PubMed
  20. Shatoor AS, Soliman H, Al-Hashem F, Gamal BE, Othman A, El-Menshaw N. Effect of hawthorn (Crataegus aronia syn. Azarolus (L)) on platelet function in albino wistar rats. Thromb Res 2012;130(1):75-80. PubMed
  21. Vibes J, Lasserre B, Gleye J, Declume C. Inhibition of thromboxane A2 biosynthesis in vitro by the main components of Crataegus oxyacantha (hawthorn) flower heads. Prostaglandins Leukot Essent Fatty Acids 1994;50(4):173-5. PubMed
  22. Rogers KL, Grice ID, Griffiths LR. Inhibition of platelet aggregation and 5-HT release by extracts of Australian plants used traditionally as headache treatments. Eur J Pharm Sci 2000;9(4):355-63. PubMed
  23. Zhou CC, Huang XX, Gao PY, et al. Two new compounds from Crataegus pinnatifida and their antithrombotic activities. J Asian Nat Prod Res 2014;16(2):169-74.
  24. Palmer KG, Lebin JA, Cronin MT, Mazor SS, Burns RA. Crataegus mexicana (Tejocote) Exposure Associated with Cardiotoxicity and a Falsely Elevated Digoxin Level. J Med Toxicol. 2019;15(4):295-298. PubMed
  25. Espinosa J, Bassett R, Lucerna A, Finn D. Hawthorne root (Crataegus mexicana) toxicity. Am J Emerg Med. 2024;78:242.e5-242.e6. PubMed

See these in context on the Hawthorn monograph →

Lemon Balm 12 references
  1. Wolbling RH, Leonhardt K. Local therapy of herpes simplex with dried extract from Melissa officinalis. Phytomedicine 1994;1:25-31.
  2. Akhondzadeh S, Noroozian M, Mohammadi M, et al. Melissa officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomised, placebo controlled trial. J Neurol Neurosurg Psychiatry 2003;74:863-6. PubMed
  3. Kennedy DO, Scholey AB, Tildesley NT, et al. Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm). Pharmacol Biochem Behav 2002;72:953-64. PubMed
  4. Albrecht M, Berger W, Laux P, Schmidt U, et al. Psychopharmaka und Verkehrssicherheit. Der Einfluß von Euvegal® - Dragees forte auf die Fahrtüchtigkeit und Kombinationswirkungen mit Alkohol Z Allg Med 1995;71:1215-25.
  5. Herberg, KW. Nebenwirkungen pflanzlicher Beruhigungsmittel/ Leistung und Befinden nach Einnahme einer Baldrian-Hopfen-Kombination. Z.Allg Med 1996;72:234-240.
  6. Soulimani R, Fleurentin J, Mortier F, et al. Neurotropic action of the hydroalcoholic extract of Melissa officinalis in the mouse. Planta Med. 1991 Apr;57:105-9.
  7. Sourgens H, Winterhoff H, Gumbinger HG, et al. Antihormonal effects of plant extracts. TSH- and prolactin-suppressing properties of Lithospermum officinale and other plants. Planta Med. 1982 Jun;45:78-86. DOI
  8. Auf'mkolk M, Ingbar JC, Amir SM, et al. Inhibition by certain plant extracts of the binding and adenylate cyclase stimulatory effect of bovine thyrotropin in human thyroid membranes. Endocrinology. 1984 Aug;115:527-34. PubMed
  9. Santini F, Vitti P, Ceccarini G, et al. In vitro assay of thyroid disruptors affecting TSH-stimulated adenylate cyclase activity. J Endocrinol Invest. 2003 Oct;26:950-5. PubMed
  10. Alijaniha F, et al. Heart palpitation relief with Melissa officinalis leaf extract: double blind, randomized, placebo controlled trial of efficacy and safety. J Ethnopharmacol. 2015;164:378-384. doi: 10.1016/j.jep.2015.02.007. Epub 2015 Feb 11. PubMed
  11. Araj-Khodaei M, Noorbala AA, Yarani R, et al. A double-blind, randomized pilot study for comparison of Melissa officinalis L. and Lavandula angustifolia Mill. with Fluoxetine for the treatment of depression. BMC Complement Med Ther. 2020;20(1):207. PubMed
  12. Kucuk U, Pham M, Raza Raja MH, Saad Shaukat MH, Clark R. Transient complete atrioventricular block associated with herbal supplement use. S D Med 2023;76(7):311-313.

See these in context on the Lemon Balm monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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