Advanced Immunity 1300 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Advanced Immunity 1300 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Advanced Immunity 1300 mg is a dietary supplement by Totally Products with 3 active ingredients. Its ingredients are commonly taken for general nutrition and energy, antioxidant support, cholesterol and metabolic health.Based on those ingredients, 328 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Spirulina, Powder, Astragalus, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Advanced Immunity 1300 mg by Totally Products
Ask about any prescription or over-the-counter medication and we check it for interactions with Advanced Immunity 1300 mg by Totally Products — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Advanced Immunity 1300 mg by Totally Products
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Advanced Immunity 1300 mg contains three active ingredients. Spirulina is a blue-green algae powder — a protein-rich whole organism.
Olive leaf extract is a concentrated form of compounds from olive leaves, separate from olive oil you'd cook with. Astragalus is a powder derived from the astragalus plant root, used in traditional herbal medicine.
The capsules also contain magnesium stearate and gelatin as inactive ingredients that help hold everything together.
Does it work?
Not established
The evidence for what this product actually does is limited. Spirulina is rated possibly effective for high blood pressure, but for everything else in the product — acne, hay fever, and anemia support — the evidence isn't established enough to rate.
Olive leaf extract and astragalus have similar gaps: the data we hold rates them insufficient evidence for the conditions they're often promoted for, including osteoarthritis, herpes zoster, and the respiratory infections. That doesn't mean they don't work; it means the research isn't there yet to say they do.
How safe is it?
Well-documented data
Spirulina is generally well tolerated by mouth, though a small number of people report stomach upset — abdominal cramps, bloating, diarrhea, nausea — plus headache, dizziness, and fatigue. Rare allergic reactions including rash and one case of anaphylaxis have been reported.
There's also a caution about quality: some spirulina products can be contaminated with toxins or heavy metals, so sourcing matters. Olive leaf extract seems well tolerated too, with occasional headache or stomach discomfort reported; one person reported acne.
Astragalus is generally well tolerated in the short term in healthy adults, though dizziness and rash have been reported in some studies. A major note: pregnancy and breastfeeding safety data for both astragalus and spirulina are insufficient — the safety data advises against astragalus in pregnancy and while breastfeeding.
For spirulina, safety data during pregnancy and lactation is not on file.
Meds to double-check
Moderate interaction found
Before taking this product, check your medications if you're on blood thinners or antiplatelet drugs (Moderate severity) — spirulina may increase bleeding risk. Also double-check if you take diabetes medications, immune-suppressing drugs, lithium, or cyclophosphamide (Moderate severity for all) — spirulina and astragalus can interfere with how they work.
No interactions are documented in our data for olive leaf extract.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
This product may appeal to someone looking for immune support, but the evidence for what it actually does isn't strong. If you take blood thinners, diabetes drugs, lithium, or immunosuppressants, check with us first — the interactions are real enough to matter.
Astragalus is best avoided if you're pregnant or breastfeeding. Talk to your pharmacist before you start, especially if you're on any regular medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 18, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Advanced Immunity 1300 mg, straight from the product label.
| Brand | Totally Products |
|---|---|
| Barcode (UPC) | 072929836138 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 18, 2023 |
| DSLD ID | 294242 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Advanced Immunity 1300 mg by Totally Products, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Spirulina, Powder | 500 mg | -- |
| Olive Leaf Extract | 300 mg | -- |
| Astragalus, Powder | 500 mg | -- |
Other ingredients: Magnesium Stearate, Gelatin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement take two (2) capsules once daily, preferably with a well balanced meal and water, or as directed by a healthcare professional.
Precautions
Caution: Do not exceed recommended dose. Do not use if safety seal is damaged or missing.
Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of the reach of children.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formulation
100% Natural
Zero Artificial ingredients Additives - chemicals Or preservatives
Boost, protect & support Natural defense your body needs!
Seals/Symbols
GMP Good Manufacturing Practice Made in the USA
Formula
Olive leaf Spirulina Astragalus
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Advanced Immunity 1300 mg by Totally Products label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Advanced Immunity 1300 mg by Totally Products
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Spirulina, Powder
Interacts with327 drugs
Blue-green algae are nutrient-rich aquatic microorganisms (such as spirulina and Klamath Lake algae) taken as a supplement for energy, nutrition, and...
Spirulina, Powder monograph & interactionsOlive Leaf Extract
No knowninteractions
Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyr...
Olive Leaf Extract monograph & interactionsAstragalus, Powder
Interacts with208 drugs
Astragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While...
Astragalus, Powder monograph & interactionsOther (inactive) ingredients: Magnesium Stearate, Gelatin. These complete the product’s ingredient list but are not active constituents.
Advanced Immunity 1300 mg by Totally Products Drug Interactions
HelloPharmacist Interaction Report
Advanced Immunity 1300 mg by Totally Products contains three active ingredients, two of which carry documented interactions with medications.
Spirulina is the product's most serious concern: it may increase bleeding risk (Moderate severity) if you're already on blood thinners or antiplatelet drugs like warfarin or aspirin, though this risk is considered unlikely based on current evidence. Both spirulina and astragalus can theoretically lower blood sugar (Moderate severity) when combined with diabetes medications, and both may interfere with immune-suppressing drugs used after transplants or for certain autoimmune conditions (Moderate severity).
Read the full breakdown — every affected drug type, severity by severity
Astragalus adds two more interactions: it might raise lithium levels and side effects in people taking it for bipolar disorder, and it may interfere with cyclophosphamide, a chemotherapy drug — though the evidence on the cyclophosphamide interaction is mixed in animal studies. We could not check olive leaf extract for drug interactions; no interaction data is on file for it.
Altogether, these interactions span 323 individual medications.
If you take any blood thinners, diabetes medications, lithium, immunosuppressants, or chemotherapy drugs, use the interaction checker below with your exact medication names before you start this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Advanced Immunity 1300 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Advanced Immunity 1300 mg interact with 328 drugs. Click any drug to see the details.
2 of the 3 ingredients in Advanced Immunity 1300 mg interact with drugs. Each result below shows which ingredient is responsible. Spirulina, Powder Astragalus, Powder
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Advanced Immunity 1300 mg — through 2 ingredients. Tap an ingredient for the detail:
Astragalus, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus, Powder + 6-mercaptopurine interactionSpirulina, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Spirulina, Powder + 6-mercaptopurine interactionAbciximabReoPro
How Abciximab interacts with Advanced Immunity 1300 mg — through 1 ingredient. Tap an ingredient for the detail:
Spirulina, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Spirulina, Powder + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Advanced Immunity 1300 mg — through 2 ingredients. Tap an ingredient for the detail:
Spirulina, PowderAnticoagulant/antiplatelet Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Spirulina, Powder + Abrocitinib interactionAstragalus, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus, Powder + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Advanced Immunity 1300 mg — through 2 ingredients. Tap an ingredient for the detail:
Spirulina, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Spirulina, Powder + Acarbose interactionAstragalus, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus, Powder + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Advanced Immunity 1300 mg — through 1 ingredient. Tap an ingredient for the detail:
Spirulina, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Spirulina, Powder + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Advanced Immunity 1300 mg — through 1 ingredient. Tap an ingredient for the detail:
Spirulina, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Spirulina, Powder + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Advanced Immunity 1300 mg — through 1 ingredient. Tap an ingredient for the detail:
Spirulina, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Spirulina, Powder + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Advanced Immunity 1300 mg — through 1 ingredient. Tap an ingredient for the detail:
Spirulina, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Spirulina, Powder + Acetaminophen, Ibuprofen interactionAcetohexamideDymelor
How Acetohexamide interacts with Advanced Immunity 1300 mg — through 2 ingredients. Tap an ingredient for the detail:
Astragalus, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus, Powder + Acetohexamide interactionSpirulina, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Spirulina, Powder + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Advanced Immunity 1300 mg — through 1 ingredient. Tap an ingredient for the detail:
Spirulina, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Spirulina, Powder + Acetylsalicylic Acid interactionAdalimumabHumira
How Adalimumab interacts with Advanced Immunity 1300 mg — through 2 ingredients. Tap an ingredient for the detail:
Spirulina, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Spirulina, Powder + Adalimumab interactionAstragalus, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus, Powder + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with Advanced Immunity 1300 mg — through 2 ingredients. Tap an ingredient for the detail:
Astragalus, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus, Powder + Adalimumab-adaz interactionSpirulina, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Spirulina, Powder + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with Advanced Immunity 1300 mg — through 2 ingredients. Tap an ingredient for the detail:
Spirulina, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Spirulina, Powder + Adalimumab-adbm interactionAstragalus, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus, Powder + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with Advanced Immunity 1300 mg — through 2 ingredients. Tap an ingredient for the detail:
Astragalus, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus, Powder + Adalimumab-afzb interactionSpirulina, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Spirulina, Powder + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with Advanced Immunity 1300 mg — through 2 ingredients. Tap an ingredient for the detail:
Spirulina, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Spirulina, Powder + Adalimumab-atto interactionAstragalus, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus, Powder + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with Advanced Immunity 1300 mg — through 2 ingredients. Tap an ingredient for the detail:
Astragalus, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus, Powder + Adalimumab-bwwd interactionSpirulina, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Spirulina, Powder + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with Advanced Immunity 1300 mg — through 2 ingredients. Tap an ingredient for the detail:
Spirulina, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Spirulina, Powder + Adalimumab-fkjp interactionAstragalus, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus, Powder + Adalimumab-fkjp interactionAlbiglutideTanzeum
How Albiglutide interacts with Advanced Immunity 1300 mg — through 2 ingredients. Tap an ingredient for the detail:
Spirulina, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Spirulina, Powder + Albiglutide interactionAstragalus, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus, Powder + Albiglutide interactionAlefaceptAmevive
How Alefacept interacts with Advanced Immunity 1300 mg — through 2 ingredients. Tap an ingredient for the detail:
Spirulina, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Spirulina, Powder + Alefacept interactionAstragalus, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus, Powder + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with Advanced Immunity 1300 mg — through 2 ingredients. Tap an ingredient for the detail:
Astragalus, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus, Powder + Alemtuzumab interactionSpirulina, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Spirulina, Powder + Alemtuzumab interactionAlogliptinNesina
How Alogliptin interacts with Advanced Immunity 1300 mg — through 2 ingredients. Tap an ingredient for the detail:
Astragalus, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus, Powder + Alogliptin interactionSpirulina, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Spirulina, Powder + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Advanced Immunity 1300 mg — through 2 ingredients. Tap an ingredient for the detail:
Spirulina, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Spirulina, Powder + Alogliptin, Metformin interactionAstragalus, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus, Powder + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Advanced Immunity 1300 mg — through 2 ingredients. Tap an ingredient for the detail:
Astragalus, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus, Powder + Alogliptin, Pioglitazone interactionSpirulina, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Spirulina, Powder + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Advanced Immunity 1300 mg — through 1 ingredient. Tap an ingredient for the detail:
Spirulina, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Spirulina, Powder + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Advanced Immunity 1300 mg — through 1 ingredient. Tap an ingredient for the detail:
Spirulina, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Spirulina, Powder + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Advanced Immunity 1300 mg — through 1 ingredient. Tap an ingredient for the detail:
Spirulina, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Spirulina, Powder + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Advanced Immunity 1300 mg — through 1 ingredient. Tap an ingredient for the detail:
Spirulina, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Spirulina, Powder + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Advanced Immunity 1300 mg — through 1 ingredient. Tap an ingredient for the detail:
Spirulina, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Spirulina, Powder + Anagrelide interactionAnifrolumab-fniaSaphnelo
How Anifrolumab-fnia interacts with Advanced Immunity 1300 mg — through 2 ingredients. Tap an ingredient for the detail:
Spirulina, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Spirulina, Powder + Anifrolumab-fnia interactionAstragalus, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus, Powder + Anifrolumab-fnia interactionAnisindioneMiradon
How Anisindione interacts with Advanced Immunity 1300 mg — through 1 ingredient. Tap an ingredient for the detail:
Spirulina, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Spirulina, Powder + Anisindione interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Advanced Immunity 1300 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Spirulina, Powder
Anticoagulant/Antiplatelet Drugs
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs. However, this is unlikely.
Spirulina blue-green algae have shown antiplatelet and anticoagulant effects in vitro. However, one preliminary study in 24 patients receiving spirulina blue-green algae 2.3 grams daily for 2 weeks showed no effect on platelet activation or measures of clotting time.
Antidiabetes Drugs
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Human research shows that spirulina blue-green algae can have hypoglycemic effects in patients with diabetes, at least some of whom were using antidiabetes drugs. However, blue-green algae does not seem to improve glycated hemoglobin (HbA1c) levels in patients with diabetes. A meta-analysis of animal studies also suggests that spirulina blue-green algae have hypoglycemic effects.
Immunosuppressants
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Blue-green algae have been shown to stimulate the immune system.
Astragalus, Powder
Antidiabetes Drugs
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.
Cyclophosphamide
Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.
Immunosuppressants
Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.
Lithium
Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.
Brand information
Manufacturer and brand details for Advanced Immunity 1300 mg, from the product label.
Totally Products
See all Totally Products products- Name
- Totally Products LLC.
- Street Address
- 1835 E Hallandale Bch Blvd Suite 425
- City
- Hallandale
- State
- FL
- ZipCode
- 33009
- Phone Number
- 1.800.924.0710
- Web Address
- www.totallynaturalremedies.com
Advanced Immunity 1300 mg by Totally Products: Common Questions
Does Advanced Immunity 1300 mg by Totally Products interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or breastfeeding?
What side effects might I notice?
Does this actually work for immunity?
What is astragalus supposed to do?
Is the quality of this product controlled?
What's the difference between this and just eating spirulina or olives?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Advanced Immunity 1300 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Advanced Immunity 1300 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Blue-green Algae
Interacts with 327 drugsBlue-green algae are nutrient-rich aquatic microorganisms (such as spirulina and Klamath Lake algae) taken as a supplement for energy, nutrition, and general wellness. Evidence for most heal...
Read the full Blue-green Algae monograph → Herb & supplement monographOlive
Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyrosol. Olive oil as part of a Mediterrane...
Read the full Olive monograph → Herb & supplement monographAstragalus
Interacts with 208 drugsAstragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While early studies are interesting, strong h...
Read the full Astragalus monograph →Sources & How We Checked
Advanced Immunity 1300 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 37 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Blue-green Algae 22 references
- Jensen GS, Ginsberg DJ, Huerta P, et al. Consumption of Aphanizomenon flos-aquae has rapid effects on the circulation and function of immune cells in humans. A novel approach to nutritional mobilization of the immune system. JANA 2000;2:50-6.
- Iwasa M, Yamamoto M, Tanaka Y, et al. Spirulina-associated hepatotoxicity. Am J Gastroenterol 2002;97:3212-13. PubMed
- Hayashi O, Katoh T, Okuwaki Y. Enhancement of antibody production in mice by dietary Spirulina platensis. J Nutr Sci Vitaminol (Tokyo) 1994;40:431-41.. PubMed
- Vitale S, Miller NR, Mejico LJ, et al. A randomized, placebo-controlled, crossover clinical trial of super blue-green algae in patients with essential blepharospasm or Meige syndrome. Am J Ophthalmol 2004;138:18-32. PubMed
- Mani UV, Desai S, Iyer U. Studies on the long-term effect of spirulina supplementation on serum lipid profile and glycated proteins in NIDDM patients. J Nutraceut 2000;2(3):25-32. DOI
- Chiu HF, Yang SP, Kuo YL, et al. Mechanisms involved in the antiplatelet effect of C-phycocyanin. Br J Nutr 2006;95:435-40. PubMed
- Hsiao G, Chou PH, Shen MY, et al. C-phycocyanin, a very potent and novel platelet aggregation inhibitor from Spirulina platensis. J Agric Food Chem 2005;53:7734-40.
- Katz M, Levine AA, Kol-Degani H, Kav-Venaki L. A compound herbal preparation (CHP) in the treatment of children with ADHD: a randomized controlled trial. J Atten Disord 2010;14:281-91. PubMed
- Madhyastha, H. K., Radha, K. S., Sugiki, M., Omura, S., and Maruyama, M. Purification of c-phycocyanin from Spirulina fusiformis and its effect on the induction of urokinase-type plasminogen activator from calf pulmonary endothelial cells. Phytomedicine PubMed
- Mazokopakis, E. E., Karefilakis, C. M., Tsartsalis, A. N., Milkas, A. N., and Ganotakis, E. S. Acute rhabdomyolysis caused by Spirulina (Arthrospira platensis). Phytomedicine. 2008;15(6-7):525-527. PubMed
- Halidou, Doudou M., Degbey, H., Daouda, H., Leveque, A., Donnen, P., Hennart, P., and Dramaix-Wilmet, M. [The effect of spiruline during nutritional rehabilitation: systematic review]. Rev.Epidemiol.Sante Publique 2008;56(6):425-431.
- Konno, T., Umeda, Y., Umeda, M., Kawachi, I., Oyake, M., and Fujita, N. [A case of inflammatory myopathy with widely skin rash following use of supplements containing Spirulina]. Rinsho Shinkeigaku 2011;51(5):330-333. PubMed
- Le TM, Knulst AC, Röckmann H. Anaphylaxis to Spirulina confirmed by skin prick test with ingredients of Spirulina tablets. Food Chem Toxicol 2014;74:309-10. PubMed
- Rzymski P, Niedzielski P, Kaczmarek N, Jurczak T, Klimaszyk P. The multidisciplinary approach to safety and toxicity assessment of microalgae-based food supplements following clinical cases of poisoning. Harmful Algae 2015;46:34-42. DOI
- Petrus M, Culerrier R, Campistron M, et al. First case report of anaphylaxis to spirulin: identification of phycocyanin as responsible allergen. Allergy 2010;65(7):924-5. PubMed
- Marles RJ, Barrett ML, Barnes J, et al. United States Pharmacopeia safety evaluation of spirulina. Crit Rev Food Sci Nutr 2011;51(7):593-604. PubMed
- Majdoub H, Ben Mansour M, Chaubet F, et al. Anticoagulant activity of a sulfated polysaccharide from the green alga Arthrospira platensis. Biochim Biophys Acta 2009;1790(10):1377-81. PubMed
- Cha BG, Kwak HW, Park AR, et al. Structural characteristics and biological performance of silk fibroin nanofiber containing microalgae spirulina extract. Biopolymers 2014;101(4):307-18. PubMed
- Jensen GS, Drapeau C, Lenninger M, Benson KF. Clinical safety of a high dose of phycocyanin-enriched aqueous extract from Arthrospira (Spirulina) platensis: results from a randomized, double-Blind, placebo-controlled study with a focus on anticoagulant ac
- Hamedifard Z, Milajerdi A, Reiner Z, Taghizadeh M, Kolahdooz F, Asemi Z. The effects of spirulina on glycemic control and serum lipoproteins in patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized con
- Moradi S, Zobeiri M, Feizi A, Clark CCT, Entezari MH. The effects of spirulina (Arthrospira platensis) supplementation on anthropometric indices, blood pressure, sleep quality, mental health, fatigue status and quality of life in patients with ulcerative
- Ghanbari F, Amerizadeh A, Behshood P, Moradi S, Asgary S. Effect of microalgae arthrospira on biomarkers of glycemic control and glucose metabolism: a systematic Review and meta-analysis. Curr Probl Cardiol 2022;47(10):100942. PubMed
Olive 2 references
- Liccardi G, D'Amato M, D'Amato G. Oleaceae pollinosis: a review. Int Arch Allergy Immunol 1996;111:210-7. PubMed
- Somerville V, Moore R, Braakhuis A. The effect of olive leaf extract on upper respiratory illness in high school athletes: A randomised control trial. Nutrients. 2019;11(2). pii: E358. PubMed
Astragalus 13 references
- Upton R, ed. Astragalus Root: Analytical, quality control, and therapeutic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia. 1999:1-25.
- Khoo KS, Ang PT. Extract of astragalus membranaceus and ligustrum lucidum does not prevent cyclophosphamide-induced myelosuppression. Singapore Med J 1995;36:387-90.
- Chu DT, Wong WL, Mavligit GM. Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionated Astragalus membranaceus in vivo. J Clin Lab Immunol 1988;25:125-9.
- Sun Y, Hersh EM, Lee SL, et al. Preliminary observations on the effects of the Chinese medicinal herbs Astragalus membranaceus and Ligustrum lucidum on lymphocyte blastogenic responses. J Biol Response Mod 1983;2:227-37..
- Ma J, Peng A, Lin S. Mechanisms of the therapeutic effect of astragalus membranaceus on sodium and water retention in experimental heart failure. Chin Med J (Engl) 1998;111:17-23.
- Matkovic Z, Zivkovic V, Korica M, et al. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. Phytother Res 2010;24:175-81.
- Zhang, J. G., Yang, N., He, H., Wei, G. H., Gao, D. S., Wang, X. L., Wang, X. Z., and Song, G. Y. [Effect of Astragalus injection on plasma levels of apoptosis-related factors in aged patients with chronic heart failure.]. Chin J Integr.Med 2005;11(3):18 PubMed
- Chen, H. W., Lin, I. H., Chen, Y. J., Chang, K. H., Wu, M. H., Su, W. H., Huang, G. C., and Lai, Y. L. A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: a phase II double-blind, randomized placebo-controlled study. Clin Invest PubMed
- Tian H, Lu J, He H, et al.The effect of Astragalus as an adjuvant treatment in type 2 diabetes mellitus: A (preliminary) meta-analysis. J Ethnopharmacol. 2016;191:206-215. doi: 10.1016/j.jep.2016.05.062. PubMed
- Hong KF, Liu PY, Zhang W, Gui DK, Xu YH. The Efficacy and Safety of Astragalus as an Adjuvant Treatment for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. J Integr Complement Med 2023. PubMed
- Chan KW, Kwong ASK, Tsui PN, et al. Add-on astragalus in type 2 diabetes and chronic kidney disease: A multi-center, assessor-blind, randomized controlled trial. Phytomedicine 2024;130:155457. PubMed
- Han X, Yu T, Chen X, Du Z, Yu M, Xiong J. Effect of Astragalus membranaceus on left ventricular remodeling in HFrEF: a systematic review and meta-analysis. Front Pharmacol 2024;15:1345797. PubMed
- Jing P, Hongzheng H, Zhenqi WU, Meijuan Z, Zuojing LI, Gang C. Long-term efficacy and safety of Huangqi ()-based Traditional Chinese Medicine in diabetic peripheral neuropathy: a Meta-analysis of randomized controlled trials. J Tradit Chin Med 2024;44(2):
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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