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Dietary supplement

AgmaGen Pomegranate Ingredients & Drug Interactions

by RSP

AgmaGen Pomegranate label
See full label image
Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking AgmaGen Pomegranate against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

AgmaGen Pomegranate is a dietary supplement by RSP with 1 active ingredient. Its ingredients are commonly taken for pre- and post-workout support, muscle pumps and exercise performance, cognitive support and mood.Based on those ingredients, 258 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are AgmaMAX. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against AgmaGen Pomegranate by RSP

Ask about any prescription or over-the-counter medication and we check it for interactions with AgmaGen Pomegranate by RSP — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of AgmaGen Pomegranate by RSP

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

AgmaGen Pomegranate is a single-ingredient powder: agmatine (under the brand AgmaMAX). Agmatine is a natural compound derived from the amino acid arginine.

The powder also contains inactive ingredients—citric acid, natural and artificial flavors, silicon dioxide, sucralose, Red #40, and Blue #1—for taste and stability.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Agmatine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: muscle recovery pump and nutrient transport.
  • We looked for evidence on: Athletic performance, Muscle strength, Exercise performance, Post-workout recovery, Muscle soreness.
  • The closest evidence on file: Agmatine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Agmatine is rated "Insufficient Reliable Evidence To Rate" for Muscle strength.

The evidence for agmatine isn't established in the data we hold. The product doesn't list a specific health claim, but agmatine has been studied for alcohol use disorder, Alzheimer disease, anxiety, athletic performance, autism spectrum disorder, and bipolar disorder—all rated as having insufficient reliable evidence to determine whether it works.

The evidence, ingredient by ingredient Agmatine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term use of agmatine appears generally well tolerated. The most common side effects reported in small clinical trials were diarrhea, indigestion (dyspepsia), and nausea—mild-to-moderate in severity.

These appeared within 2–3 days and stopped once people quit taking it. However, long-term safety in humans hasn't been well studied.

There isn't enough safety data during pregnancy, so the data advises against use. There also isn't enough safety data while breastfeeding, so avoidance is advised.

Talk with your doctor or pharmacist if you're pregnant, planning pregnancy, or breastfeeding.

Side effects, ingredient by ingredient Agmatine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Agmatine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 258 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your blood pressure and diabetes medications before taking this product. Agmatine may theoretically increase the risk of low blood pressure or low blood sugar when combined with drugs from either of these categories.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This is a single-ingredient agmatine supplement. It may be worth a closer look if you're interested in agmatine's potential, but evidence for most claimed uses is still insufficient.

If you take blood pressure or diabetes medication, check this product with your pharmacist before starting. Short-term digestive upset is possible.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about AgmaGen Pomegranate, straight from the product label.

Brand RSP
Barcode (UPC) 852113002620
Net contents 2.8 oz.; 80 Gram(s)
Market status On market
Date entered into DSLD Aug 25, 2015
DSLD ID 49501
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for AgmaGen Pomegranate by RSP, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1.6 Gram(s)
Maximum serving Sizes:
1.6 Gram(s)
Servings per container
50
UPC/BARCODE
852113002620
IngredientAmount% DV
Calories0 {Calories}, 0 {Calories}--
AgmaMAX1000 mg, 500 mg--

Other ingredients: Citric Acid, Natural & Artificial flavors, Silicon Dioxide, Sucralose, Red #40, Blue #1

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

AgmaGen:(TM) The Science ~Increases nitric oxide production for maximum pump and nutrient transport. ~Facilitates muscle recovery and repair, reducing soreness and recovery time needed between workouts. ~Promotes antioxidant activity and combats free radicals to support a healthy immune system and muscle function. ~Increase oxygen supply to muscle tissues to maximize work capacity.

Increase endurance Build muscle Burn Fat Recover Faster

50 Servings

Seals/Symbols

{American Flag} MADE IN THE USA

RSP Nutrition

Suggested/Recommended/Usage/Directions

Directions: Take a scoop with 4-6oz of water 20 mins before training or stack with your favorite pre-workout. For best results take an additional scoop during training.

1 {scoop} + 4-6oz {water bottle}

Precautions

If you have any health condition, are pregnant, breast feeding or taking medication, ask a physician before use.

Keep out of reach of small children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

100% pure AGMAMAX(TM) Agmatine Sulfate

Natural & Artificial flavors

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

AgmaGen Pomegranate by RSP label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

AgmaGen Pomegranate label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in AgmaGen Pomegranate by RSP

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1.6 Gram(s) Dosage formPowder Servings per container50 Amounts shown are per serving.

AgmaMAX

Interacts with
258 drugs
1000 mg per serving

Agmatine is a compound your body makes from the amino acid arginine, and it is sold mainly as a workout and 'pump' supplement. Human evidence for most...

AgmaMAX monograph & interactions

Other (inactive) ingredients: Citric Acid, Natural & Artificial flavors, Silicon Dioxide, Sucralose, Red #40, Blue #1. These complete the product’s ingredient list but are not active constituents.

Interaction report

AgmaGen Pomegranate by RSP Drug Interactions

Want to check YOUR meds against AgmaGen Pomegranate?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
258Drugs
258 Moderate

Ingredients driving the most interactions

AgmaMAX 258

Individual Drug Interactions

The ingredients in AgmaGen Pomegranate interact with 258 drugs. Click any drug to see the details.

1 of the 1 ingredient in AgmaGen Pomegranate interact with drugs. Each result below shows which ingredient is responsible. AgmaMAX

Each ingredient & the kinds of drugs it affects

For each ingredient in AgmaGen Pomegranate with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

AgmaMAX2 drug types · 258 drugs

Antidiabetes Drugs

Theoretically, agmatine might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggest that agmatine has mild hypoglycemic effects.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, agmatine might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that agmatine can modestly decrease heart rate and blood pressure.

Likelihood Possible Evidence D
AgmaMAX full monograph & interactions
The maker

Brand information

Manufacturer and brand details for AgmaGen Pomegranate, from the product label.

RSP

See all RSP products
Name
RSP Nutrition
Street Address
PO Box 398776
City
Miami Beach
State
FL
ZipCode
33239
Phone Number
877-814-2544
Web Address
www.rspnutrition.com
Pharmacist Counseling Corner

AgmaGen Pomegranate by RSP: Common Questions

Does AgmaGen Pomegranate by RSP interact with any medications?
Yes. Based on its ingredients, AgmaGen Pomegranate has a known interaction with 258 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
AgmaGen Pomegranate contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No. There isn't enough safety data, so the safety information advises against use during pregnancy and while breastfeeding. Talk with your doctor or pharmacist for personalized guidance if you're pregnant, planning pregnancy, or nursing.
What side effects might I get?
Diarrhea, indigestion, and nausea are the most commonly reported side effects. They tend to be mild-to-moderate and usually show up within a few days. They typically go away once you stop taking the product.
How long has agmatine been tested for safety?
Short-term use looks generally well tolerated in human trials, but long-term safety in humans hasn't been well studied. If you're thinking of using this for weeks or months, that's worth discussing with your pharmacist.
Does agmatine actually work for any condition?
The research so far isn't strong enough to say. Agmatine has been studied for alcohol use, Alzheimer disease, anxiety, athletic performance, autism, and bipolar disorder, but all of those are rated as having insufficient evidence to determine whether it works.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if AgmaGen Pomegranate is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

AgmaGen Pomegranate label
Go deeper

The Full Monographs Behind AgmaGen Pomegranate’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Agmatine

Interacts with 258 drugs

Agmatine is a compound your body makes from the amino acid arginine, and it is sold mainly as a workout and 'pump' supplement. Human evidence for most of its claimed benefits is limited and...

Read the full Agmatine monograph →
Sources

Sources & How We Checked

AgmaGen Pomegranate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Agmatine 3 references
  1. Piletz JE, Aricioglu F, Cheng JT, et al. Agmatine: clinical applications after 100 years in translation. Drug Discov Today 2013;18(17-18):880-93. PubMed
  2. Keynan O, Mirovsky Y, Dekel S, Gilad VH, Gilad GM. Safety and efficacy of dietary agmatine sulfate in lumbar disc-associated radiculopathy. An open-label, dose-escalating study followed by a randomized, double-blind, placebo-controlled trial. Pain Med 201 PubMed
  3. Shopsin B. The clinical antidepressant effect of exogenous agmatine is not reversed by parachlorophenylalanine: a pilot study. Acta Neuropsychiatr 2013;25(2):113-8. PubMed

See these in context on the Agmatine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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