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Dietary supplement

Agmatine Sulfate Ingredients & Drug Interactions

by FN Formutech Nutrition

Agmatine Sulfate label
See full label image
Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Agmatine Sulfate against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Agmatine Sulfate is a dietary supplement by FN Formutech Nutrition with 1 active ingredient. Its ingredients are commonly taken for pre- and post-workout support, muscle pumps and exercise performance, cognitive support and mood.Based on those ingredients, 258 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Agmatine Sulfate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Agmatine Sulfate by FN Formutech Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Agmatine Sulfate by FN Formutech Nutrition — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Agmatine Sulfate by FN Formutech Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: agmatine sulfate. It's a compound naturally found in the body that's involved in nerve signaling and metabolism.

There are no other inactive ingredients listed.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Agmatine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: increase and maintain nitric oxide levels for muscle pumps.
  • We looked for evidence on: Athletic performance, Muscle strength, Exercise performance, Muscle endurance.
  • The closest evidence on file: Agmatine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Agmatine is rated "Insufficient Reliable Evidence To Rate" for Muscle strength.

The evidence for agmatine's effectiveness is not yet established. Our data rates its potential benefits for alcohol use disorder, Alzheimer disease, anxiety, athletic performance, autism spectrum disorder, and bipolar disorder all as 'insufficient reliable evidence to rate' — meaning the science simply isn't there yet to say whether it works for these uses.

The evidence, ingredient by ingredient Agmatine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term use of agmatine appears generally well tolerated, but long-term safety in humans hasn't been well studied. The most common side effects from oral use are diarrhea, upset stomach (dyspepsia), and nausea.

In two small clinical trials, a small number of participants taking 3.56 grams daily experienced mild-to-moderate diarrhea and nausea within 2 to 3 days; these effects resolved once they stopped the supplement. There isn't enough safety data for pregnancy or breastfeeding, so the safety data advises against use in both.

Side effects, ingredient by ingredient Agmatine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Agmatine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 258 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your pharmacist if you're on blood pressure medications or diabetes medications — both carry Moderate risk of increased side effects (low blood pressure or low blood sugar) when combined with agmatine.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Agmatine sulfate is a single-ingredient supplement that's generally well tolerated short-term, but its long-term safety and effectiveness aren't yet proven. If you take blood pressure or diabetes medications, check with your pharmacist before starting — this product could theoretically make both work harder.

Talk to your pharmacist about whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Agmatine Sulfate, straight from the product label.

Brand FN Formutech Nutrition
Barcode (UPC) 748252003607
Net contents 1.76 Ounce(s); 50 Gram(s)
Market status On market
Date entered into DSLD Jan 22, 2022
DSLD ID 259060
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Agmatine Sulfate by FN Formutech Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
500 mg
Maximum serving Sizes:
500 mg
Servings per container
100
UPC/BARCODE
748252003607
IngredientAmount% DV
Agmatine Sulfate500 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Agmatine Sulfate helps to increase and maintain nitric oxide levels in your body for long periods of time resulting in longer lasting muscle pumps.

Suggested/Recommended/Usage/Directions

Directions: Mix 1/2 to 1 scoop Agmatine Sulfate with your pre-workout or beverage of choice and consume approximately 20-30 minutes before training.

Precautions

Warning: Keep out of reach of children.

Do not use if pregnant or nursing.

Consult your doctor prior to use if you have or are at risk for prostate disease, heart disease, or any other general medical condition.

Consult your doctor prior to use If you're taking any other medications.

Do not exceed suggested dosage.

Caution: Persons or athletes that are subject to performance enhancement testing should consult with their sanctioning body before use.

Not suitable for persons under the age of 18 years old.

General Statements

100 servings

Formulation

Long lasting muscle pumps Enhances performance Increase endurance

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Agmatine Sulfate by FN Formutech Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Agmatine Sulfate label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Agmatine Sulfate by FN Formutech Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size500 mg Dosage formPowder Servings per container100 Amounts shown are per serving.

Agmatine Sulfate

Interacts with
258 drugs
500 mg per serving

Agmatine is a compound your body makes from the amino acid arginine, and it is sold mainly as a workout and 'pump' supplement. Human evidence for most...

Agmatine Sulfate monograph & interactions
Interaction report

Agmatine Sulfate by FN Formutech Nutrition Drug Interactions

Want to check YOUR meds against Agmatine Sulfate?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
258Drugs
258 Moderate

Ingredients driving the most interactions

Agmatine Sulfate 258

Individual Drug Interactions

The ingredients in Agmatine Sulfate interact with 258 drugs. Click any drug to see the details.

1 of the 1 ingredient in Agmatine Sulfate interact with drugs. Each result below shows which ingredient is responsible. Agmatine Sulfate

Each ingredient & the kinds of drugs it affects

For each ingredient in Agmatine Sulfate with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Agmatine Sulfate2 drug types · 258 drugs

Antidiabetes Drugs

Theoretically, agmatine might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggest that agmatine has mild hypoglycemic effects.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, agmatine might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that agmatine can modestly decrease heart rate and blood pressure.

Likelihood Possible Evidence D
Agmatine Sulfate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Agmatine Sulfate, from the product label.

FN Formutech Nutrition

See all FN Formutech Nutrition products
Name
Formutech Nutrition
City
Norcross
State
GA
ZipCode
30071
Phone Number
888-839-7962
Web Address
FNUTRITION.COM
Pharmacist Counseling Corner

Agmatine Sulfate by FN Formutech Nutrition: Common Questions

Does Agmatine Sulfate by FN Formutech Nutrition interact with any medications?
Yes. Based on its ingredients, Agmatine Sulfate has a known interaction with 258 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Agmatine Sulfate contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What are the most common side effects?
Diarrhea, upset stomach, and nausea are the main ones reported. In small trials, these were mild to moderate and went away once people stopped taking it.
Is it safe to take long-term?
The data we have is from short-term use, and it looks well tolerated. Long-term safety in humans just hasn't been studied well enough to say.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety data for either pregnancy or breastfeeding, so the safety data advises against it. Talk with your doctor or pharmacist for personalized advice.
Does agmatine actually work for any of the conditions listed?
The evidence isn't established yet. Our data rates it as 'insufficient reliable evidence' for all the uses listed — meaning we don't know from the research whether it works.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Agmatine Sulfate is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Agmatine Sulfate label
Go deeper

The Full Monographs Behind Agmatine Sulfate’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Agmatine

Interacts with 258 drugs

Agmatine is a compound your body makes from the amino acid arginine, and it is sold mainly as a workout and 'pump' supplement. Human evidence for most of its claimed benefits is limited and...

Read the full Agmatine monograph →
Sources

Sources & How We Checked

Agmatine Sulfate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Agmatine 3 references
  1. Piletz JE, Aricioglu F, Cheng JT, et al. Agmatine: clinical applications after 100 years in translation. Drug Discov Today 2013;18(17-18):880-93. PubMed
  2. Keynan O, Mirovsky Y, Dekel S, Gilad VH, Gilad GM. Safety and efficacy of dietary agmatine sulfate in lumbar disc-associated radiculopathy. An open-label, dose-escalating study followed by a randomized, double-blind, placebo-controlled trial. Pain Med 201 PubMed
  3. Shopsin B. The clinical antidepressant effect of exogenous agmatine is not reversed by parachlorophenylalanine: a pilot study. Acta Neuropsychiatr 2013;25(2):113-8. PubMed

See these in context on the Agmatine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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