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Dietary supplement

Agmatine Sulfate 500 mg Ingredients & Drug Interactions

by OL Olympian Labs, Inc. Performance Sports Nutrition

Agmatine Sulfate 500 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Agmatine Sulfate 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Agmatine Sulfate 500 mg is a dietary supplement by OL Olympian Labs, Inc. Performance Sports Nutrition with 1 active ingredient. Its ingredients are commonly taken for pre- and post-workout support, muscle pumps and exercise performance, cognitive support and mood.Based on those ingredients, 258 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Agmatine Sulfate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Agmatine Sulfate 500 mg by OL Olympian Labs, Inc. Performance Sports Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Agmatine Sulfate 500 mg by OL Olympian Labs, Inc. Performance Sports Nutrition — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Agmatine Sulfate 500 mg by OL Olympian Labs, Inc. Performance Sports Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: agmatine sulfate at 500 mg per capsule. Agmatine is a compound derived from the amino acid arginine that has been studied for potential effects on blood pressure, blood sugar, and certain neurological conditions.

The capsule also contains several inactive ingredients—vegetarian capsule material, ascorbyl palmitate, microcrystalline cellulose, silica, and rice flour—which serve as the capsule shell and flow agents.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Agmatine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: muscle pump, vascularity, endurance, blood flow.
  • We looked for evidence on: Athletic performance, Muscle strength, Exercise performance, Nitric oxide production, Post-workout recovery.
  • The closest evidence on file: Agmatine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Agmatine is rated "Insufficient Reliable Evidence To Rate" for Muscle strength.

The evidence for agmatine's effectiveness is not yet established. The data we hold rates it as having insufficient reliable evidence for alcohol use disorder, Alzheimer disease, anxiety, athletic performance, autism spectrum disorder, and bipolar disorder.

If you're considering this product for one of these purposes, the science hasn't yet shown whether it works, and you should talk with your pharmacist or doctor about whether it's right for you.

The evidence, ingredient by ingredient Agmatine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Agmatine appears generally well tolerated in the short term at typical doses. The most common side effects reported in small studies were diarrhea, dyspepsia (indigestion), and nausea—and these typically appeared within 2–3 days and resolved once people stopped taking it.

However, long-term safety in humans hasn't been well studied. There isn't enough safety data for pregnancy or breastfeeding, so the safety data advises against use in both.

If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Agmatine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Agmatine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 258 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check it with any blood pressure medication (antihypertensive) you're taking—agmatine may theoretically increase the risk of low blood pressure. Also check it with any diabetes medication (antidiabetes drug), since it may theoretically raise the risk of low blood sugar.

Both are Moderate-severity interactions. Use the search tool on this page to verify your exact drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Agmatine sulfate is a single-ingredient supplement that's generally well tolerated short-term, but the evidence that it actually works for any specific condition isn't established yet. It poses a moderate risk of lowering blood pressure or blood sugar if you're on medications for either condition.

If you take any blood pressure or diabetes drugs, check your specific medications before starting, and talk with your pharmacist about whether it's appropriate for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Agmatine Sulfate 500 mg, straight from the product label.

Brand OL Olympian Labs, Inc. Performance Sports Nutrition
Barcode (UPC) 710013001252
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Apr 25, 2018
DSLD ID 175816
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), No Allergies, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Agmatine Sulfate 500 mg by OL Olympian Labs, Inc. Performance Sports Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
710013001252
IngredientAmount% DV
Agmatine Sulfate500 mg--

Other ingredients: Vegetarian Capsule, Ascorbyl Palmitate, Microcrystalline Cellulose, Silica, Rice Flour

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Agmatine Sulfate helps increase nitric oxide (NO) production & drives the NO & other nutrients into muscles which can increase muscle pump, vascularity & provide greater endurance.

Agmatine Sulfate is known as the next generation of Arginine.

Studies suggest Agmatine Sulfate doesn't just mimic the benefits of Arginine, it frequently surpasses them.

The additional affects include an increase in blood flow, improved dilation of blood vessels & an increase in anti-oxidant delivery.

Studies have also shown Agmatine Sulfate to have pain & stress-fighting effects & can aid in post-workout recovery & muscle repair.

Olympian Labs, Inc. products are made with the highest quality ingredients and manufactured according to current Good Manufacturing Practices (cGMP).

Helps increase lean muscle mass Helps decrease recovery time May increase nitric oxide production Muscle growth Recovery

We do not use ingredients that were produced using modern biotechnology

Made in USA

Precautions

Caution: If you are pregnant or nursing, have a medical condition, or are taking medication, consult your healthcare professional before using this or any other nutritional supplement.

Discontinue use if allergic reaction occurs.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General

REV 03.01.17

Storage

Store in a cool, dry place.

Formula

Agmatine Sulfate 500 mg per serving

Formulation

Vegetarian

Gluten free Allergen free

Non-GMO

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Pre-workout Intra-workout Suggested Use: As a dietary supplement, take two (2) capsules, or as directed by a healthcare professional. Take 30-60 minutes before your workout. To maximize results take an additional serving during training.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Agmatine Sulfate 500 mg by OL Olympian Labs, Inc. Performance Sports Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Agmatine Sulfate 500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Agmatine Sulfate 500 mg by OL Olympian Labs, Inc. Performance Sports Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Agmatine Sulfate

Interacts with
258 drugs
500 mg per serving

Agmatine is a compound your body makes from the amino acid arginine, and it is sold mainly as a workout and 'pump' supplement. Human evidence for most...

Agmatine Sulfate monograph & interactions

Other (inactive) ingredients: Vegetarian Capsule, Ascorbyl Palmitate, Microcrystalline Cellulose, Silica, Rice Flour. These complete the product’s ingredient list but are not active constituents.

Interaction report

Agmatine Sulfate 500 mg by OL Olympian Labs, Inc. Performance Sports Nutrition Drug Interactions

Want to check YOUR meds against Agmatine Sulfate 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
258Drugs
258 Moderate

Ingredients driving the most interactions

Agmatine Sulfate 258

Individual Drug Interactions

The ingredients in Agmatine Sulfate 500 mg interact with 258 drugs. Click any drug to see the details.

1 of the 1 ingredient in Agmatine Sulfate 500 mg interact with drugs. Each result below shows which ingredient is responsible. Agmatine Sulfate

Each ingredient & the kinds of drugs it affects

For each ingredient in Agmatine Sulfate 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Agmatine Sulfate2 drug types · 258 drugs

Antidiabetes Drugs

Theoretically, agmatine might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggest that agmatine has mild hypoglycemic effects.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, agmatine might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that agmatine can modestly decrease heart rate and blood pressure.

Likelihood Possible Evidence D
Agmatine Sulfate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Agmatine Sulfate 500 mg, from the product label.

OL Olympian Labs, Inc. Performance Sports Nutrition

See all OL Olympian Labs, Inc. Performance Sports Nutrition products
Name
Olympian Labs, Inc.
City
Phoenix
State
AZ
ZipCode
85027
Phone Number
1-800-473-5883
Web Address
www.olympianlabs.com
Pharmacist Counseling Corner

Agmatine Sulfate 500 mg by OL Olympian Labs, Inc. Performance Sports Nutrition: Common Questions

Does Agmatine Sulfate 500 mg by OL Olympian Labs, Inc. Performance Sports Nutrition interact with any medications?
Yes. Based on its ingredients, Agmatine Sulfate 500 mg has a known interaction with 258 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Agmatine Sulfate 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is agmatine, and what is it supposed to do?
Agmatine is a compound made from the amino acid arginine. It's been studied for potential effects on blood pressure, blood sugar, and some neurological conditions, but the evidence that it actually works for any of these isn't established in the data we hold.
What side effects might I experience?
The most common side effects are diarrhea, indigestion, and nausea. In small studies, these appeared within 2–3 days of starting and went away once people stopped taking it. Agmatine seems well tolerated short-term, but long-term safety hasn't been well studied in humans.
Can I take this if I'm pregnant or breastfeeding?
No—there isn't enough safety data, so the safety data advises against use during pregnancy and while breastfeeding. Talk with your doctor or pharmacist for personalized advice if you're in either situation.
I take blood pressure medication. Is this safe for me?
Agmatine may theoretically lower your blood pressure further when combined with blood pressure medication, raising the risk of dangerously low blood pressure. Check your specific medication with the search tool on this page, and talk with your pharmacist before starting.
I'm diabetic. Can I take this?
Agmatine may theoretically lower your blood sugar further when combined with diabetes medication, raising the risk of low blood sugar (hypoglycemia). Check your specific medication with the search tool on this page, and talk with your pharmacist before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Agmatine Sulfate 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Agmatine Sulfate 500 mg label
Go deeper

The Full Monographs Behind Agmatine Sulfate 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Agmatine

Interacts with 258 drugs

Agmatine is a compound your body makes from the amino acid arginine, and it is sold mainly as a workout and 'pump' supplement. Human evidence for most of its claimed benefits is limited and...

Read the full Agmatine monograph →
Sources

Sources & How We Checked

Agmatine Sulfate 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Agmatine 3 references
  1. Piletz JE, Aricioglu F, Cheng JT, et al. Agmatine: clinical applications after 100 years in translation. Drug Discov Today 2013;18(17-18):880-93. PubMed
  2. Keynan O, Mirovsky Y, Dekel S, Gilad VH, Gilad GM. Safety and efficacy of dietary agmatine sulfate in lumbar disc-associated radiculopathy. An open-label, dose-escalating study followed by a randomized, double-blind, placebo-controlled trial. Pain Med 201 PubMed
  3. Shopsin B. The clinical antidepressant effect of exogenous agmatine is not reversed by parachlorophenylalanine: a pilot study. Acta Neuropsychiatr 2013;25(2):113-8. PubMed

See these in context on the Agmatine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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