Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Ahiflower Oil Omega 3-6-9 Ingredients & Drug Interactions

by Natural Traditions

Ahiflower Oil Omega 3-6-9 label
See full label image
Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Ahiflower Oil Omega 3-6-9 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Ahiflower Oil Omega 3-6-9 is a dietary supplement by Natural Traditions with 4 active ingredients. Its ingredients are commonly taken for general nutrition and energy, skin conditions like eczema, inflammation support.Based on those ingredients, 375 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Omega 3 Fatty Acids:, Oleic Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Ahiflower Oil Omega 3-6-9 by Natural Traditions

Ask about any prescription or over-the-counter medication and we check it for interactions with Ahiflower Oil Omega 3-6-9 by Natural Traditions — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Ahiflower Oil Omega 3-6-9 by Natural Traditions

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 5 of its 6 active ingredients.
  • “Omega-6 Fatty Acids” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Omega 3 Fatty Acids:” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

This product delivers six active fatty acid ingredients: gamma-linolenic acid, omega-6 fatty acids (including linoleic acid), oleic acid, alpha-linolenic acid, stearidonic acid, and ahiflower seed oil. Ahiflower is a plant source of omega-3 and omega-6 fatty acids.

The softgel also contains a few inactive ingredients — a vegan gel shell, rosemary extract (as an antioxidant), tocopherols, and ascorbyl palmitate — which are there to hold the product together and keep it fresh.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Plant-based omega 3-6-9 fatty acid nutrition.
  • We looked for evidence on: Cardiovascular disease (CVD), Coronary heart disease (CHD), Hypercholesterolemia, Hyperlipidemia, Hypertension, Atopic dermatitis (eczema) — and 4 related terms.
  • The strongest evidence on file: Oleic Acid is rated "Possibly Effective" for Coronary heart disease (CHD) (Natural Medicines).
  • Also on file: Oleic Acid is rated "Possibly Effective" for Hypercholesterolemia.
  • Also on file: Oleic Acid is rated "Insufficient Reliable Evidence To Rate" for Hypertension.

Oleic acid, one of this product's ingredients, is rated possibly effective for high cholesterol and coronary heart disease. The evidence isn't overwhelming, but preliminary research suggests it may help.

For the other fatty acids in this product — gamma-linolenic acid, linoleic acid, alpha-linolenic acid, stearidonic acid, and ahiflower oil — we don't hold effectiveness data in our records.

The evidence, ingredient by ingredient Omega-6 Fatty Acids Oleic Acid Docosahexaenoic Acid (dha)

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oleic acid from food sources like olive oil is generally recognized as safe in the amounts people typically eat. However, concentrated supplement doses of oleic acid haven't been well studied, particularly in pregnancy and while breastfeeding.

The safety data we hold is limited to what's known about food amounts. No adverse effects were reported in the trial data we have on file.

We could not check gamma-linolenic acid, linoleic acid, alpha-linolenic acid, stearidonic acid, or ahiflower oil itself for safety information — that data isn't available to us.

Side effects, ingredient by ingredient Omega-6 Fatty Acids Oleic Acid Docosahexaenoic Acid (dha)

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Oleic Acid.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs (blood sugar medications), check your exact prescription before starting this product — oleic acid may increase their effects and you might need monitoring. We could not check gamma-linolenic acid, linoleic acid, alpha-linolenic acid, stearidonic acid, or ahiflower oil for interactions, so run those names through the search tool if you're on any other prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

This omega blend may be worth considering if you're looking for oleic acid and have checked that it won't increase your blood sugar medication too much. If you take antidiabetes drugs, talk to your pharmacist first — it's the main interaction to watch.

For everything else in this product, we're missing the safety data, so a conversation with your pharmacist is a good idea before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Ahiflower Oil Omega 3-6-9, straight from the product label.

Brand Natural Traditions
Barcode (UPC) 627733000604
Net contents 90 Vegetarian Softgel(s)
Market status On market
Date entered into DSLD Mar 24, 2016
DSLD ID 57133
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Ahiflower Oil Omega 3-6-9 by Natural Traditions, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Vegetarian Softgel(s)
Maximum serving Sizes:
3 Vegetarian Softgel(s)
Servings per container
30
UPC/BARCODE
627733000604
IngredientAmount% DV
Calories20 {Calories}--
Calories from Fat20 {Calories}--
Gamma-Linolenic Acid102 mg--
Omega-6 Fatty Acids0 NP--
Total Fat2.5 Gram(s)4%
Linoleic Acid204 mg--
Oleic Acid135 mg--
Alpha-Linolenic Acid855 mg--
Stearidonic Acid384 mg--
Ahiflower (Buglossoides arvensis) seed oil0 NP--
Omega 3 Fatty Acids:0 NP--

Other ingredients: Vegan Gel Shell, antioxidant Rosemary extract, Tocopherols, Ascorbyl Palmitate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

ECO-CONSCIOUS NON-MARINE OMEGA 3

VEGAN

ahiflower

Refrigerate after opening.

Formula

100% Plant-Based Omega 3 (ALA Plus SDA)

Unlike these seed oils, Ahiflower oil is the richest source of SDA (stearidonic acid) which converts more eficiently to the Omega 3 fatty acid EPA that is found in fish oil.

Ahiflower oil also contains beneficial Omega 6 gamma linolenic acid (GLA). A true Omega 3 and Omega 6 powerhouse with ALA, SDA and GLA, delivering a healthy 4 to 1 balance of Omega 3 to Omega 6, Ahiflower oil is the most eco-conscious, sustainable way to get the benefits of EPA found in fish oil from a vegan, plant-based source.

General Statements

Up to 4 times greater EPA conversion than Flax Seed Oil More effective Omega 3 & 6 than Flax, Chia, or Hemp Seed Oil 4:1 Omega 3 to Omega 6 Ratio

A new generation in superior plant-based omegas

While there are many sources of plant based Omega-3 ALA such as flax, chia, sacha inchi and hemp seed oil, these seeds do not offer optimal conversion to EPA.

Country of origin: USA

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Take 3 softgels per day with food.

Fully close bottle after each use.

Brand IP Statement(s)

Ahiflower oil is the richest and most effective combined Omega-3 (SDA and ALA) and Omega-6 (GLA and LA) fatty acid source from a single non-GMO plant found in nature.

A human clinical trial found that Ahiflower oil has up to 3-4 times greater conversion rate to Omega 3 EPA compared to flax seed oil.

Better Than Flax. Not From Fish.

Formulation

A true Omega 3 and Omega 6 powerhouse with ALA, SDA and GLA, delivering a healthy 4 to 1 balance of Omega 3 to Omega 6, Ahiflower oil is the most eco-conscious, sustainable way to get the benefits of EPA found in fish oil from a vegan, plant-based source.

Precautions

Warning: Keep out of reach of children.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Ahiflower Oil Omega 3-6-9 by Natural Traditions label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Ahiflower Oil Omega 3-6-9 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Ahiflower Oil Omega 3-6-9 by Natural Traditions

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Vegetarian Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Omega-6 Fatty Acids

No known
interactions
0 NP per serving

Omega-6 fatty acids are essential fats your body needs but cannot make on its own, and most people get plenty from everyday foods like vegetable oils,...

Omega-6 Fatty Acids monograph & interactions
  • › Gamma-Linolenic Acid
  • › Linoleic Acid

Oleic Acid

Interacts with
86 drugs
135 mg per serving

Oleic acid is a heart-healthy monounsaturated fat found mainly in olive oil, canola oil, avocados, and nuts. As part of a Mediterranean-style diet, it...

Oleic Acid monograph & interactions

Ahiflower (Buglossoides arvensis) seed oil

0 NP per serving

Omega 3 Fatty Acids:

Interacts with
375 drugs
0 NP per serving

DHA is an omega-3 fatty acid found in fatty fish and algae that is a building block for the brain, nervous system, and eyes. It is widely used and gen...

Omega 3 Fatty Acids: monograph & interactions
  • › Alpha-Linolenic Acid
  • › Stearidonic Acid

Other (inactive) ingredients: Vegan Gel Shell, Antioxidant Rosemary extract, Tocopherols, Ascorbyl Palmitate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Ahiflower Oil Omega 3-6-9 by Natural Traditions Drug Interactions

Want to check YOUR meds against Ahiflower Oil Omega 3-6-9?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
375Drugs
375 Moderate

Ingredients driving the most interactions

Omega 3 Fatty Acids: 375
Oleic Acid 86

Individual Drug Interactions

The ingredients in Ahiflower Oil Omega 3-6-9 interact with 375 drugs. Click any drug to see the details.

2 of the 4 ingredients in Ahiflower Oil Omega 3-6-9 interact with drugs. Each result below shows which ingredient is responsible. Omega 3 Fatty Acids: Oleic Acid

Each ingredient & the kinds of drugs it affects

For each ingredient in Ahiflower Oil Omega 3-6-9 with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Omega 3 Fatty Acids:3 drug types · 375 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Although some clinical evidence suggests that DHA might reduce collagen-stimulated platelet aggregation and thromboxane release, most clinical evidence suggests that DHA alone does not affect blood clotting. However, theoretically, when given in combination with EPA as fish oil, concomitant use with anticoagulant or antiplatelet drugs (including aspirin) might increase risk of bleeding.

Likelihood Unlikely Evidence B
Antidiabetes Drugs

Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
In people with type 2 diabetes, including those taking oral hypoglycemic medications, DHA seems to increase fasting blood glucose levels.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Fish oils containing DHA can lower blood pressure and might have additive effects in patients treated with antihypertensives; use with caution.

Likelihood Probable Evidence B
Omega 3 Fatty Acids: full monograph & interactions

Oleic Acid1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, oleic acid might increase the effects of antidiabetes drugs. Preliminary clinical research in patients with type 2 diabetes taking oral hypoglycemic drugs shows that eating a diet rich in oleic acid from olive oil decreases fasting blood glucose levels when compared to eating a diet rich in linoleic acid from sunflower oil. It is unknown if taking oleic acid supplements would have this effect or if this change is clinically significant. Until more is known, use caution. Dose adjustment may be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence B
Oleic Acid full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Ahiflower Oil Omega 3-6-9, from the product label.

Natural Traditions

See all Natural Traditions products
Name
Health Matters America Inc.
Street Address
2501 Broadway Street, Unit 2
City
Buffalo
State
NY
ZipCode
14227
Phone Number
1-800-304-1497
Web Address
www.healthmattersamerica.com
Pharmacist Counseling Corner

Ahiflower Oil Omega 3-6-9 by Natural Traditions: Common Questions

Does Ahiflower Oil Omega 3-6-9 by Natural Traditions interact with any medications?
Yes. Based on its ingredients, Ahiflower Oil Omega 3-6-9 has a known interaction with 375 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Ahiflower Oil Omega 3-6-9 contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What are omega-3 and omega-6 fatty acids supposed to do?
They're essential fats your body uses for cell structure, brain function, and reducing inflammation. This product gives you both from plant sources. Oleic acid in it is rated possibly effective for cholesterol and heart health, but the other fatty acids here don't have established evidence in our data.
Is this safe to take while I'm pregnant or breastfeeding?
The only ingredient we have pregnancy data for is oleic acid — supplement-level doses haven't been well studied during pregnancy or nursing. The amounts in food are considered fine, but concentrated supplements are not. Talk to your doctor or pharmacist for personalized advice about whether this product is right for you right now.
Does this product contain any fillers or artificial ingredients?
The inactive ingredients are a vegan gel shell, rosemary extract (an antioxidant), tocopherols, and ascorbyl palmitate. These are there to hold the softgel together and prevent spoilage. No artificial colors or sweeteners are listed.
I take metformin for diabetes. Can I take this?
Oleic acid in this product may theoretically increase your blood sugar medication's effects, so you'll want to check it with your pharmacist first. Don't start without talking to them — they can tell you if monitoring or a dose adjustment is needed.
What's ahiflower, and is it the same as flax or fish oil?
Ahiflower is a plant seed oil with its own fatty acid profile. It's different from flax and fish oil, though all three are omega sources. This product uses ahiflower as one of its sources.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Ahiflower Oil Omega 3-6-9 is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Ahiflower Oil Omega 3-6-9 label
Go deeper

The Full Monographs Behind Ahiflower Oil Omega 3-6-9’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Omega-6 Fatty Acids

Omega-6 fatty acids are essential fats your body needs but cannot make on its own, and most people get plenty from everyday foods like vegetable oils, nuts, and seeds. Supplements such as ev...

Read the full Omega-6 Fatty Acids monograph → Herb & supplement monograph

Oleic Acid

Interacts with 86 drugs

Oleic acid is a heart-healthy monounsaturated fat found mainly in olive oil, canola oil, avocados, and nuts. As part of a Mediterranean-style diet, it is widely viewed as a healthier replace...

Read the full Oleic Acid monograph → Herb & supplement monograph

Docosahexaenoic Acid (dha)

Interacts with 375 drugs

DHA is an omega-3 fatty acid found in fatty fish and algae that is a building block for the brain, nervous system, and eyes. It is widely used and generally well tolerated, with the stronges...

Read the full Docosahexaenoic Acid (dha) monograph →
Sources

Sources & How We Checked

Ahiflower Oil Omega 3-6-9's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 88 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Omega-6 Fatty Acids 20 references
  1. Godley PA. Essential fatty acid consumption and risk of breast cancer. Breast Cancer Res Treat 1995;35:91-5. PubMed
  2. Newcomer LM, King IB, Wicklund KG, Stanford JL. The association of fatty acids with prostate cancer risk. Prostate 2001;47:262-8. DOI
  3. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Energy, Carbohydrate. Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/books/03 DOI
  4. Colter, A. L., Cutler, C., and Meckling, K. A. Fatty acid status and behavioural symptoms of attention deficit hyperactivity disorder in adolescents: a case-control study. Nutr J 2008;7:8. PubMed
  5. Yamada, T., Strong, J. P., Ishii, T., Ueno, T., Koyama, M., Wagayama, H., Shimizu, A., Sakai, T., Malcom, G. T., and Guzman, M. A. Atherosclerosis and omega-3 fatty acids in the populations of a fishing village and a farming village in Japan. Atheroscler
  6. Conklin, S. M., Manuck, S. B., Yao, J. K., Flory, J. D., Hibbeln, J. R., and Muldoon, M. F. High omega-6 and low omega-3 fatty acids are associated with depressive symptoms and neuroticism. Psychosom.Med. 2007;69(9):932-934.
  7. Richardson, A. J., Cyhlarova, E., and Ross, M. A. Omega-3 and omega-6 fatty acid concentrations in red blood cell membranes relate to schizotypal traits in healthy adults. Prostaglandins Leukot.Essent.Fatty Acids 2003;69(6):461-466. PubMed
  8. Assies, J., Lok, A., Bockting, C. L., Weverling, G. J., Lieverse, R., Visser, I., Abeling, N. G., Duran, M., and Schene, A. H. Fatty acids and homocysteine levels in patients with recurrent depression: an explorative pilot study. Prostaglandins Leukot.Es PubMed
  9. Chiplonkar, S. A., Agte, V. V., Tarwadi, K. V., Paknikar, K. M., and Diwate, U. P. Micronutrient deficiencies as predisposing factors for hypertension in lacto-vegetarian Indian adults. J Am Coll.Nutr 2004;23(3):239-247. PubMed
  10. Mamalakis, G., Kiriakakis, M., Tsibinos, G., Hatzis, C., Flouri, S., Mantzoros, C., and Kafatos, A. Depression and serum adiponectin and adipose omega-3 and omega-6 fatty acids in adolescents. Pharmacol.Biochem.Behav. 2006;85(2):474-479. PubMed
  11. Okuyama, H., Ichikawa, Y., Sun, Y., Hamazaki, T., and Lands, W. E. Cancers common in the USA are stimulated by omega 6 fatty acids and large amounts of animal fats, but suppressed by omega 3 fatty acids and cholesterol. World Rev Nutr Diet. 2007;96:143-1
  12. Martinez-Ramirez, M. J., Palma, S., Martinez-Gonzalez, M. A., Delgado-Martinez, A. D., de la Fuente, C., and Delgado-Rodriguez, M. Dietary fat intake and the risk of osteoporotic fractures in the elderly. Eur.J Clin Nutr 2007;61(9):1114-1120. PubMed
  13. Sonestedt, E., Gullberg, B., and Wirfalt, E. Both food habit change in the past and obesity status may influence the association between dietary factors and postmenopausal breast cancer. Public Health Nutr 2007;10(8):769-779. PubMed
  14. Simopoulos, A. P. The omega-6/omega-3 fatty acid ratio, genetic variation, and cardiovascular disease. Asia Pac.J Clin Nutr 2008;17 Suppl 1:131-134.
  15. Harris, W. S., Mozaffarian, D., Rimm, E., Kris-Etherton, P., Rudel, L. L., Appel, L. J., Engler, M. M., Engler, M. B., and Sacks, F. Omega-6 fatty acids and risk for cardiovascular disease: a science advisory from the American Heart Association Nutrition DOI
  16. Godley, P. A., Campbell, M. K., Gallagher, P., Martinson, F. E., Mohler, J. L., and Sandler, R. S. Biomarkers of essential fatty acid consumption and risk of prostatic carcinoma. Cancer Epidemiol.Biomarkers Prev. 1996;5(11):889-895.
  17. Lee E, Kim H, Kim H, Ha EH, Chang N. Association of maternal omega-6 fatty acid intake with infant birth outcomes: Korean Mothers and Children's Environmental Health (MOCEH). Nutr J 2018;17(1):47. PubMed
  18. Pawelczyk T, Trafalska E, Pawelczyk A, Kotlicka-Antczak M. Differences in omega-3 and omega-6 polyunsaturated fatty acid consumption in people at ultra-high risk of psychosis, first-episode schizophrenia, and in healthy controls. Early Interv Psychiatry 2
  19. Gardner KG, Gebretsadik T, Hartman TJ, et al. Prenatal omega-3 and omega-6 polyunsaturated fatty acids and childhood atopic dermatitis. J Allergy Clin Immunol Pract. 2020;8(3):937-944. PubMed
  20. Luo J, Ge H, Sun J, Hao K, Yao W, Zhang D. Associations of dietary ?-3, ?-6 fatty acids consumption with sleep disorders and sleep duration among adults. Nutrients 2021;13(5):1475. PubMed

See these in context on the Omega-6 Fatty Acids monograph →

Oleic Acid 19 references
  1. Madigan C, Ryan M, Owens D, et al. Dietary unsaturated fatty acids in type 2 diabetes: higher levels of postprandial lipoprotein on a linoleic acid-rich sunflower oil diet compared with an oleic acid-rich olive oil diet. Diabetes Care 2000;23:1472-7. PubMed
  2. Gillingham, L. G., Gustafson, J. A., Han, S. Y., Jassal, D. S., and Jones, P. J. High-oleic rapeseed (canola) and flaxseed oils modulate serum lipids and inflammatory biomarkers in hypercholesterolaemic subjects. Br J Nutr 2011;105(3):417-427. PubMed
  3. Jones PJ, Senanayake VK, Pu S, Jenkins DJ, Connelly PW, Lamarche B, Couture P, Charest A, Baril-Gravel L, West SG, Liu X, Fleming JA, McCrea CE, Kris-Etherton PM. DHA-enriched high-oleic acid canola oil improves lipid profile and lowers predicted cardiova
  4. Cater, N. B., Heller, H. J., and Denke, M. A. Comparison of the effects of medium-chain triacylglycerols, palm oil, and high oleic acid sunflower oil on plasma triacylglycerol fatty acids and lipid and lipoprotein concentrations in humans. Am.J Clin.Nutr PubMed
  5. Mozaffarian D, Clarke R. Quantitative effects on cardiovascular risk factors and coronary heart disease risk of replacing partially hydrogenated vegetable oils with other fats and oils. Eur J Clin Nutr. 2009;63(Suppl 2):S22-33. PubMed
  6. Cao Y, Hou L, Wang W. Dietary total fat and fatty acids intake, serum fatty acids and risk of breast cancer: A meta-analysis of prospective cohort studies. Int J Cancer. 2016;138(8):1894-904. doi: 10.1002/ijc.29938. PubMed
  7. FDA completes review of qualified health claim petition for oleic acid and the risk of coronary heart disease. November 2018. Available at: www.fda.gov/Food/NewsEvents/ConstituentUpdates/ucm624758.htm. Accessed January 25, 2019.
  8. Liu X, Kris-Etherton PM, West SG, et al. Effects of canola and high-oleic-acid canola oils on abdominal fat mass in individuals with central obesity. Obesity. 2016;24(11):2261-2268. PubMed
  9. Bowen KJ, Kris-Etherton PM, West SG, et al. Diets enriched with conventional or high-oleic acid canola oils lower atherogenic lipids and lipoproteins compared to a diet with a western fatty acid profile in adults with central adiposity. J Nutr. 2019;149(3 PubMed
  10. Steffen BT, Duprez D, Szklo M, Guan W, Tsai MY. Circulating oleic acid levels are related to greater risks of cardiovascular events and all-cause mortality: The Multi-Ethnic Study of Atherosclerosis. J Clin Lipidol. 2018;12(6):1404-1412. PubMed
  11. Banim PJ, Luben R, Khaw KT, Hart AR. Dietary oleic acid is inversely associated with pancreatic cancer - Data from food diaries in a cohort study. Pancreatology. 2018;18(6):655-660. PubMed
  12. Morin SJ, Gaziano JM, Djoussé L. Relation between plasma phospholipid oleic acid and risk of heart failure. Eur J Nutr. 2018;57(8):2937-2942. PubMed
  13. Samieri C, Féart C, Proust-Lima C, et al. Olive oil consumption, plasma oleic acid, and stroke incidence: the Three-City Study. Neurology. 2011;77(5):418-25. PubMed
  14. Compher CW, Kinosian BP, Rubesin SE, Ratcliffe SJ, Metz DC. Energy absorption is reduced with oleic acid supplements in human short bowel syndrome. JPEN J Parenter Enteral Nutr. 2009;33(1):102-8. PubMed
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See these in context on the Docosahexaenoic Acid (dha) monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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