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Dietary supplement

Alkanet Root Powder Ingredients & Drug Interactions

by Bixa Botanical

Alkanet Root Powder label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Alkanet Root Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Alkanet Root Powder is a dietary supplement by Bixa Botanical with 1 active ingredient. Its ingredients are commonly taken for wound healing, burns and skin ulcers, natural red dye for foods and cosmetics.Based on those ingredients, 87 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Alkanna tinctoria powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Alkanet Root Powder by Bixa Botanical

Ask about any prescription or over-the-counter medication and we check it for interactions with Alkanet Root Powder by Bixa Botanical — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Alkanet Root Powder by Bixa Botanical

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: alkanna tinctoria powder. Traditionally used for burns and wound healing, alkanna is applied topically far more often than taken by mouth.

The powder itself has no inactive ingredients listed.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: wound healing and burns support.
  • We looked for evidence on: Burns, Wound healing, Skin ulcers, Skin irritation.
  • The closest evidence on file: Alkanna is rated "Insufficient Reliable Evidence To Rate" for Burns (Natural Medicines).
  • Also on file: Alkanna is rated "Insufficient Reliable Evidence To Rate" for Wound healing.

The evidence we hold doesn't establish that alkanna works for burns or wound healing—the ratings are insufficient reliable evidence for both uses. That said, the bigger issue is safety rather than whether it's effective.

The evidence, ingredient by ingredient Alkanna

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Here's the critical point: alkanna contains pyrrolizidine alkaloids (PAs)—compounds that are toxic to the liver, lungs, and cells. Oral use carries a real risk of liver damage, including a condition called veno-occlusive disease, which can cause stomach pain, vomiting, diarrhea, fluid buildup in the belly, and liver enlargement within weeks of repeated exposure.

The safety data advises against use during pregnancy and while breastfeeding due to these alkaloid toxins and lack of safety information. Topically, absorption of these alkaloids is also a concern.

If you're considering alkanna for any reason, oral use especially should be avoided.

Side effects, ingredient by ingredient Alkanna

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Alkanna.
  • The most serious interaction on file is rated Moderate.
  • For scale: 88 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take drugs that speed up CYP3A4 metabolism—such as carbamazepine, phenobarbital, phenytoin, rifampin, or rifabutin—do not use this product without checking with your doctor or pharmacist first. A Moderate interaction exists, and the underlying liver toxicity risk is significant.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Alkanet root powder isn't recommended for oral use because of its liver-toxic alkaloid content and the risk of serious harm. While topical use is more common in traditional practice, the safety profile remains a concern.

Talk with your doctor or pharmacist before using this product in any form—especially if you take medications that induce CYP3A4 enzymes, which could worsen the toxicity risk.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Alkanet Root Powder, straight from the product label.

Brand Bixa Botanical
Barcode (UPC) 8904289004839
Net contents 200 Gram(s); 7 Ounce(s)
Market status On market
Date entered into DSLD Jul 23, 2020
DSLD ID 229577
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Alkanet Root Powder by Bixa Botanical, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Gram(s)
Maximum serving Sizes:
3 Gram(s)
Servings per container
66
UPC/BARCODE
8904289004839
IngredientAmount% DV
Alkanna tinctoria powder3 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Half - one teaspoon with warm water daily as required or as directed by your health practitioner.

Brand IP Statement(s)

Trademark of Bixa Botanical INC, USA

Formulation

Supports as natural-coloring agent

Vegan

Non GMO

FDA Statement of Identity

Herbal Food Supplement

FDA Disclaimer Statement

Disclaimer: These statements have not been evaluated by the Food and Drug Administration and this product is a herbal food supplement and not intended to diagnose, treat, cure or prevent a disease.

Precautions

Warning: This product is not intended for use by those with serious medical condition or pregnant or lactating women.

Consult your physician before use.

Do not use if seal is broken.

Keep out of reach of children.

Storage

Store in a cool and dry place.

General Statements

Product of India

Over 140 years of quality trust

More than a company, Bixa Botanical is a dream - to share the collective knowledge of five generations of a family with the world; secrets of Herbal Healing that have been painstakingly accumulated over the last 140 years. Over 500 varieties of herbs are exclusively cleaned, processed and packed-in the company's ultra-modern in-house facilities.

Mfg. Lic. No : MP25D/14/318

Seals/Symbols

Good manufacturing practices GMP Certified K LBD (Kosher)

Formula

K LBD (Kosher)

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Alkanet Root Powder by Bixa Botanical label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Alkanet Root Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Alkanet Root Powder by Bixa Botanical

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Gram(s) Dosage formPowder Servings per container66 Amounts shown are per serving.

Alkanna tinctoria powder

Interacts with
87 drugs
3 Gram(s) per serving

Alkanna is a Mediterranean plant whose red root has long been used as a dye and as a folk skin remedy for wounds and burns. Human evidence for any hea...

Alkanna tinctoria powder monograph & interactions
Interaction report

Alkanet Root Powder by Bixa Botanical Drug Interactions

Want to check YOUR meds against Alkanet Root Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
87Drugs
87 Moderate

Ingredients driving the most interactions

Alkanna tinctoria powder 87

Individual Drug Interactions

The ingredients in Alkanet Root Powder interact with 87 drugs. Click any drug to see the details.

1 of the 1 ingredient in Alkanet Root Powder interact with drugs. Each result below shows which ingredient is responsible. Alkanna tinctoria powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Alkanet Root Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Alkanna tinctoria powder1 drug type · 87 drugs

Cytochrome P450 3A4 (Cyp3A4) Inducers

Hepatotoxic pyrrolizidine alkaloids (PAs) are substrates of cytochrome P450 3A4 (CYP3A4). Theoretically, drugs that induce CYP3A4 might increase the conversion of PAs to toxic metabolites. Some drugs that induce CYP3A4 include carbamazepine (Tegretol), phenobarbital, phenytoin (Dilantin), rifampin, rifabutin (Mycobutin), and others.

Likelihood Possible Evidence D
Alkanna tinctoria powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Alkanet Root Powder, from the product label.

Bixa Botanical

See all Bixa Botanical products
Name
S.A.Herbal Bioactives LLP
Street Address
Plot No: 101, Sector - 1, Pithampur, Dist. Dhar (M.P)
State
454 775
Phone Number
+91 22 2783 1232
Web Address
[email protected]
Pharmacist Counseling Corner

Alkanet Root Powder by Bixa Botanical: Common Questions

Does Alkanet Root Powder by Bixa Botanical interact with any medications?
Yes. Based on its ingredients, Alkanet Root Powder has a known interaction with 87 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Alkanet Root Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No. The safety data advises against use in both pregnancy and while breastfeeding because of the potential for liver-toxic alkaloid damage and a lack of safety information. Talk with your doctor or pharmacist about safe alternatives.
Does this actually work for burns or wound healing?
The evidence we hold is insufficient to rate whether alkanna works for either purpose. But given the safety concerns with oral use, that's secondary to whether it's safe to take at all.
Is this safe to use orally?
The safety data advises against oral use. Alkanna contains liver-toxic compounds that can cause serious harm, including liver disease with symptoms like stomach pain, vomiting, and diarrhea. Topical use is more traditional, but carries its own absorption risk—talk with your doctor or pharmacist before using it in any form.
What are the pyrrolizidine alkaloids in alkanna?
They're naturally occurring compounds in the plant that damage the liver, lungs, and cells. Chronic exposure to plants containing these alkaloids is linked to veno-occlusive disease, a serious liver condition.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Alkanet Root Powder label
Go deeper

The Full Monographs Behind Alkanet Root Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Alkanna

Interacts with 87 drugs

Alkanna is a Mediterranean plant whose red root has long been used as a dye and as a folk skin remedy for wounds and burns. Human evidence for any health benefit is very limited, and because...

Read the full Alkanna monograph →
Sources

Sources & How We Checked

Alkanet Root Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Alkanna 6 references
  1. WHO working group. Pyrrolizidine alkaloids. Environmental Health Criteria, 80. WHO: Geneva, 1988.
  2. Chojkier M. Hepatic sinusoidal-obstruction syndrome: toxicity of pyrrolizidine alkaloids. J Hepatol 2003;39:437-46. PubMed
  3. Roeder E. Medicinal plants in Europe containing pyrrolizidine alkaloids. Pharmazie 1995;50:83-98.
  4. Wang YP, Yan J, Fu PP, Chou MW. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid. Toxicol Lett 2005;155:411-20. PubMed
  5. Gümüs K, Özlü ZK. The effect of a beeswax, olive oil and Alkanna tinctorial (L.) Tausch mixture on burn injuries: An experimental study with a control group. Complement Ther Med. 2017;34:66-73.
  6. Kheiri A, Amini S, Javidan AN, Saghafi MM, Khorasani G. The effects of Alkanna tinctoria Tausch on split-thickness skin graft donor site management: a randomized, blinded placebo-controlled trial. BMC Complement Altern Med. 2017;17(1):253. PubMed

See these in context on the Alkanna monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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