Alpha Yohimbine Ingredients & Drug Interactions
by T6 Team Six
What is this page for?
First and foremost: checking Alpha Yohimbine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Alpha Yohimbine is a dietary supplement by T6 Team Six with 1 active ingredient. Its ingredients are commonly taken for high blood pressure, anxiety and agitation, sleep problems.Based on those ingredients, 840 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Rauwolfia vomitoria. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Alpha Yohimbine by T6 Team Six
Ask about any prescription or over-the-counter medication and we check it for interactions with Alpha Yohimbine by T6 Team Six — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Alpha Yohimbine by T6 Team Six
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Alpha Yohimbine is a single-ingredient capsule: rauwolfia vomitoria, a plant extract that contains potent alkaloids, including yohimbine and reserpine. The capsule itself is made from hypromellose and cellulose, with ascorbyl palmitate as an added inactive ingredient.
Does it work?
Not established
The evidence for rauwolfia vomitoria in this product isn't established. We have no reliable data rating it for athletic performance, diabetes management, or psychosis.
If you're considering this product for any of those purposes, talk to your pharmacist about whether the science supports it.
How safe is it?
Well-documented data
Rauwolfia vomitoria is possibly unsafe taken by mouth due to potent alkaloids that can cause serious effects — low blood pressure, depression, and rare movement disorders like akathisia and tremor. The product safety data advises against use during pregnancy and while breastfeeding, since alkaloids may pass into breast milk and safety is unknown.
Because this ingredient contains small amounts of reserpine and yohimbine, it carries a real risk of adverse effects even at standard doses.
Meds to double-check
Major interaction found
Before you take Alpha Yohimbine, run these medication types through the checker on this page: antipsychotic drugs, stimulants, levodopa, MAO inhibitor antidepressants (Major severity interactions), and blood pressure medications, diabetes drugs, and liver enzyme substrates like certain antidepressants and pain relievers (Moderate severity). The ingredient has documented interactions with a large number of individual medications across these categories.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.
Alpha Yohimbine is a potent, single-ingredient supplement with significant documented interactions and serious safety concerns. If you take any antipsychotic, antidiabetes, blood pressure, or stimulant medication — or an MAOI antidepressant — you should check with your pharmacist before considering this product.
Pregnant people and those breastfeeding should avoid it entirely. Anyone interested in this supplement should discuss it with their pharmacist first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Alpha Yohimbine, straight from the product label.
| Brand | T6 Team Six |
|---|---|
| Net contents | 60 Veggie Cap(s) |
| Market status | On market |
| Date entered into DSLD | Feb 25, 2019 |
| DSLD ID | 190976 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Alpha Yohimbine by T6 Team Six, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Rauwolfia vomitoria | 2 mg | -- |
Other ingredients: Hypromellose, Cellulose, Ascorbyl Palmitate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement take 1 capsule 1-2 times per day. Do not take within 6 hours of bedtime.
Precautions
Do not take within 6 hours of bedtime.
Warning: Not intended for use by persons under age 18.
Do not exceed recommended dose. Do not take for more than 8 consecutive weeks.
This product should not be taken by pregnant or lactating women. Get the consent of a licensed physician before using this product, especially if you are taking medication, have a medical condition, or thinking about becoming pregnant.
Caution should be taken when consuming with caffeinated products. Do not consume with products in excess of 200 mg of caffeine.
Keep this product and all supplements out of the reach of children.
Formula
Alpha Yohimbine is designed to help promote: Fat burning potential Increased focus Healthy libido
Premium Rauwolscine
2 mg Rauwolfia vomitoria (Alpha Yohimbine)
Yohimbine works by increasing adrenaline levels in the body, as well as inhibiting a regulatory process in fat cells, which normally suppresses fat burning.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to treat, diagnose, cure or prevent any disease.
General Statements
We support our troops
Fat-burning compound, primarily used to lose fat during short term fasting.
Clinically dosed
Seals/Symbols
Third Party Tested
No Hidden Ingredients
GMP
3rd Party Tested
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Alpha Yohimbine by T6 Team Six label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Alpha Yohimbine by T6 Team Six
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Vcap(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Rauwolfia vomitoria
Interacts with840 drugs
Rauvolfia vomitoria is an African shrub whose root contains powerful alkaloids, including reserpine, that have historically been used for high blood p...
Rauwolfia vomitoria monograph & interactionsOther (inactive) ingredients: Hypromellose, Cellulose, Ascorbyl Palmitate. These complete the product’s ingredient list but are not active constituents.
Alpha Yohimbine by T6 Team Six Drug Interactions
HelloPharmacist Interaction Report
Alpha Yohimbine by T6 Team Six contains rauwolfia vomitoria, which interacts with a significant number of medications.
The most serious concern is with antipsychotic drugs — this ingredient may increase their effects and the risk of adverse reactions, including movement problems like akathisia and tremor.
Read the full breakdown — every affected drug type, severity by severity
Yohimbine, one of the active compounds in rauwolfia vomitoria, acts as a stimulant and raises blood pressure. Taking this product with stimulant drugs (like pseudoephedrine or prescription ADHD medications) could cause additive stimulant effects and dangerous blood pressure elevation.
Rauwolfia vomitoria can also interfere with levodopa (used for Parkinson's disease) by reducing its effectiveness and worsening movement symptoms.
The ingredient has moderate interactions with blood pressure medications — it may lower your blood pressure further — and with diabetes drugs, which could increase the risk of low blood sugar (hypoglycemia). It may also slow how your body clears certain medications by blocking a liver enzyme (CYP2D6), raising their levels.
Additionally, combining this product with sedating drugs or MAO inhibitor antidepressants (a specific older class) carries serious risks.
Additionally, CNS depressants (drugs that cause drowsiness) may have stronger sedative effects. Altogether, these interactions span 837 individual medications.
Use the medication checker on this page to look up any prescriptions you're currently taking before you start this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Alpha Yohimbine?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Alpha Yohimbine interact with 840 drugs. Click any drug to see the details.
1 of the 1 ingredient in Alpha Yohimbine interact with drugs. Each result below shows which ingredient is responsible. Rauwolfia vomitoria
AbciximabReoPro
How Abciximab interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Abrocitinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Acetaminophen, Aspirin interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Acetaminophen, Ibuprofen interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Acetylsalicylic Acid interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Anisindione interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Aspirin interactionAspirin, ButalbitalAxotal
How Aspirin, Butalbital interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Aspirin, Butalbital interactionAspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium OxideBufferin
How Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interactionAspirin, CarisoprodolSoma Compound
How Aspirin, Carisoprodol interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Aspirin, Carisoprodol interactionAspirin, Citric Acid, Sodium BicarbonateAlka-Seltzer Pain Reliever and Antacid
How Aspirin, Citric Acid, Sodium Bicarbonate interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Aspirin, Citric Acid, Sodium Bicarbonate interactionAspirin, DipyridamoleAggrenox, Asasantin Retard
How Aspirin, Dipyridamole interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Aspirin, Dipyridamole interactionAspirin, MeprobamateMicrainin
How Aspirin, Meprobamate interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Aspirin, Meprobamate interactionAspirin, MethocarbamolRobaxisal
How Aspirin, Methocarbamol interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Aspirin, Methocarbamol interactionAspirin, OmeprazoleYosprala
How Aspirin, Omeprazole interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Aspirin, Omeprazole interactionBetrixabanBevyxxa
How Betrixaban interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Betrixaban interactionBivalirudinAngiomax, Angiomax Rtu, Angiox
How Bivalirudin interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Bivalirudin interactionBromfenac SodiumBromsite, Prolensa
How Bromfenac Sodium interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Bromfenac Sodium interactionCabliviCablivi
How Cablivi interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Cablivi interactionCangrelorKengreal
How Cangrelor interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Cangrelor interactionCilostazolPletal
How Cilostazol interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Cilostazol interactionClopidogrelPlavix
How Clopidogrel interacts with Alpha Yohimbine — through 1 ingredient. Tap an ingredient for the detail:
Rauwolfia VomitoriaAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Read the full Rauwolfia Vomitoria + Clopidogrel interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Alpha Yohimbine with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Rauwolfia vomitoria
Antipsychotic Drugs
Theoretically, concomitant use might increase the risk of adverse effects.
Concomitant use of neuroleptics with Rauvolfia vomitoria may potentiate the effects of these drugs and the rauwolfia alkaloids.
Levodopa
Theoretically, Rauvolfia vomitoria might reduce the effects of levodopa.
Avoid using Rauvolfia vomitoria with levodopa; concomitant use may reduce drug effectiveness and increase extrapyramidal motor symptoms.
Monoamine Oxidase Inhibitors (Maois)
Theoretically, concomitant use might cause additive effects.
Yohimbine, a constituent of Rauvolfia vomitoria, has MAO inhibitory effects. At high doses, yohimbine is a non-selective inhibitor of MAO.
Stimulant Drugs
Theoretically, concomitant use might cause additive effects.
Yohimbine, a constituent of Rauvolfia vomitoria, has sympathomimetic effects and increases blood pressure in a dose-dependent manner. Theoretically, taking Rauvolfia vomitoria with stimulant drugs can have additive stimulant and hypertensive effects.
Antidiabetes Drugs
Theoretically, taking Rauvolfia vomitoria with antidiabetes drugs might increase the risk of hypoglycemia.
Preliminary clinical research shows that drinking a beverage containing Rauvolfia vomitoria foliage and bitter orange fruit lowers blood glucose levels. Hypoglycemic effects of Rauvolfia vomitoria have also been demonstrated in an animal diabetic model.
Antihypertensive Drugs
Theoretically, Rauvolfia vomitoria might increase the risk of hypotension.
Rauvolfia vomitoria contains a very small amount of the drug reserpine. Reserpine can reduce both systolic and diastolic blood pressure.
Cns Depressants
Theoretically, taking Rauvolfia vomitoria might cause additive sedative effects.
Rauvolfia vomitoria has sedative effects in animal research.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, Rauvolfia vomitoria might increase the levels and clinical effects of CYP2D6 substrates.
Rauvolfia vomitoria contains small amounts of the drug yohimbine. In vitro research shows that yohimbine inhibits CYP2D6 enzyme activity.
Ephedrine
Theoretically, Rauvolfia vomitoria might alter the effects and side effects of ephedrine.
Rauvolfia vomitoria contains resperine, which might reduce indirect-sympathomimetic drug activity. However, another constituent of Rauvolfia vomitoria, yohimbine, has stimulant activity and may increase the risk of adverse effects with ephedrine.
Tricyclic Antidepressants (Tcas)
Theoretically, concomitant use might alter the effects of Rauvolfia vomitoria and increase the risk for adverse effects.
A small clinical study in patients taking TCAs for at least 4 weeks shows that receiving doses of intravenous yohimbine, a constituent of Rauvolfia vomitoria, 2.5-20 mg daily for up to 7 days precipitates severe anxiety, agitation, and tremor. Also, concomitant use of TCAs with Rauvolfia vomitoria may decrease the effects of rauwolfia alkaloids.
Anticoagulant/Antiplatelet Drugs
Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.
Rauvolfia vomitoria contains small amounts of yohimbine. Research in healthy adults shows that taking yohimbine in doses of 8 mg or more seems to inhibit platelet aggregation in vitro by binding to the alpha-2 adrenoceptor. The effects of Rauvolfia vomitoria itself are unclear.
Brand information
Manufacturer and brand details for Alpha Yohimbine, from the product label.
T6 Team Six
See all T6 Team Six products- Name
- Team Six Supplements
- City
- Alpharetta
- State
- GA
- ZipCode
- 30005
- Web Address
- www.t6supplements.com
Alpha Yohimbine by T6 Team Six: Common Questions
Does Alpha Yohimbine by T6 Team Six interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What's actually in this capsule?
Does it really work for athletic performance or building muscle?
Can I take it if I'm on blood pressure medication?
What are the side effects I should watch for?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Alpha Yohimbine is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Alpha Yohimbine’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Alpha Yohimbine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 46 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Rauvolfia Vomitoria 46 references
- Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Milman N, Scheibel J, Jessen O. Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol 1980;60:85-7.
- Teloken C, Rhoden EL, Sogari P, et al. Therapeutic effects of high dose yohimbine hydrochloride on organic erectile dysfunction. J Urol 1998;159:122-4. PubMed
- Jacobsen FM. Fluoxetine-induced sexual dysfunction and an open trial of yohimbine. J Clin Psychiatry 1992;53:119-22.
- Hollander E, McCarley A. Yohimbine treatment of sexual side effects induced by serotonin reuptake blockers. J Clin Psychiatry 1992;53:207-9.
- Sandler B, Aronson P. Yohimbine-induced cutaneous drug eruption, progressive renal failure, and lupus-like syndrome. Urol 1993;41:343-5. PubMed
- Kearney T, Tu N, Haller C. Adverse drug events associated with yohimbine-containing products: a retrospective review of the California Poison Control System reported cases. Ann Pharmacother 2010;44:1022-9. PubMed
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