Major interaction on record — check this product against your medications before combining. Based on 7 of 11 ingredients. Check your meds →
Dietary supplement

Amino Build SX-7 Revolution White Raspberry Freezie Ingredients & Drug Interactions

by MuscleTech

Amino Build SX-7 Revolution White Raspberry Freezie label
See full label image
Powder Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Amino Build SX-7 Revolution White Raspberry Freezie against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Amino Build SX-7 Revolution White Raspberry Freezie is a dietary supplement by MuscleTech with 11 active ingredients. Its ingredients are commonly taken for morning sickness in pregnancy, premenstrual syndrome (pms), preventing or treating b6 deficiency.Based on those ingredients, 781 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Caffeine, Vitamin B6, Taurine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Amino Build SX-7 Revolution White Raspberry Freezie by MuscleTech

Ask about any prescription or over-the-counter medication and we check it for interactions with Amino Build SX-7 Revolution White Raspberry Freezie by MuscleTech — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Amino Build SX-7 Revolution White Raspberry Freezie by MuscleTech

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 11 of its 11 active ingredients.
  • “2:1:1 Micro-BCAA Complex Matrix” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “Intravol Musclebuilding Matrix” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “NeuroSphere Energy & Focus Matrix” is a proprietary blend — the label doesn't break down how much of each component you get.

Amino Build SX-7 Revolution contains 11 active ingredients. The core amino acids are L-glutamine, L-isoleucine, L-valine, and L-leucine — branched-chain amino acids (BCAAs) that support muscle building and recovery.

It also includes three B vitamins: vitamin B6, vitamin B12, and betaine anhydrous (a compound that works with these vitamins). Taurine is included for its possible effects on heart and liver health, and durian fruit extract adds flavor and antioxidants.

Caffeine is present for mental alertness and athletic performance. The product also contains blended proprietary matrices — including a 2:1:1 Micro-BCAA Complex Matrix, an Intravol Musclebuilding Matrix, and a NeuroSphere Energy & Focus Matrix — whose individual components aren't listed separately.

Six inactive ingredients (citric acid, flavoring, malic acid, silicon dioxide, sucralose, and acesulfame potassium) round out the powder.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: explosive energy enhanced focus increased strength performance.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Exercise-induced muscle soreness, Attention, Cognitive function, Muscle strength and endurance — and 2 related terms.
  • The strongest evidence on file: Caffeine is rated "Likely Effective" for Athletic performance (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Caffeine is rated "Possibly Ineffective" for Attention deficit-hyperactivity disorder (ADHD).

Evidence for this product's ingredients is mixed. Glutamine is effective for sickle cell disease and possibly effective for muscle wasting related to HIV/AIDS and for recovery after surgery or critical illness.

Vitamin B6 is effective for certain anemias and vitamin B6 deficiency, and possibly effective for pregnancy-related nausea. Vitamin B12 is effective for B12 deficiency and certain rare conditions, and possibly effective for canker sores.

Betaine anhydrous is effective for homocystinuria and possibly effective for high homocysteine levels, but evidence is insufficient for its use in fatty liver disease, colorectal adenoma, depression, or acid reflux. Taurine is possibly effective for heart failure and possibly ineffective for obesity.

Caffeine is effective for staying alert and possibly helps athletic performance. For L-isoleucine, L-valine, L-leucine, durian, and Japanese raisin tree extract, we hold no effectiveness data.

The product's blended matrices also lack individual effectiveness ratings in our data.

The evidence, ingredient by ingredient Vitamin B6 Vitamin B12 Glutamine Betaine Anhydrous Taurine Durian Caffeine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 7 of the 7 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 7 of 7.
  • General safety write-ups exist for 7 of 7.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most ingredients are generally well tolerated. Glutamine is well tolerated in healthy adults but should be used only under medical supervision by people with kidney or liver disease; common side effects include belching, bloating, constipation, diarrhea, flatulence, nausea, and vomiting.

High-dose glutamine may cause dizziness or headache, and two cases of mania have been reported in people with bipolar disorder. Vitamin B6 is safe at normal doses but high doses over time can harm nerves (sensory neuropathy); common effects include headache, nausea, and abdominal pain.

Vitamin B12 is very safe with no upper limit and is needed in pregnancy and breastfeeding. Betaine is generally well tolerated but may cause body odor, nausea, vomiting, diarrhea, or GI distress.

Taurine is well tolerated short-term in healthy adults; rare hypersensitivity reactions have occurred. Caffeine at moderate doses is typically well tolerated but can cause anxiety, insomnia, jitteriness, headache, nausea, and diarrhea; rare serious effects include stroke.

Durian is generally safe as a food but is high in sugar and calories. Data on L-isoleucine, L-valine, L-leucine, and Japanese raisin tree extract safety is not on file.

Pregnant people should discuss caffeine and glutamine with their doctor; glutamine has insufficient safety data in pregnancy and lactation.

Side effects, ingredient by ingredient Vitamin B6 Vitamin B12 Glutamine Betaine Anhydrous Taurine Durian Caffeine

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 6 of the 7 matched ingredients can interact with medications — Glutamine, Vitamin B12, Vitamin B6, Caffeine, Taurine, among others.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications; diabetes medications; lithium; Parkinson's medications.
  • For scale: 781 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before taking this product if you use ephedrine (Major interaction with caffeine), antihypertensive drugs (blood pressure medications), seizure medications including phenobarbital, phenytoin, and carbamazepine, the heart rhythm drug amiodarone, the antipsychotic clozapine, the sedative pentobarbital, the blood thinner dipyridamole, acid reflux medication cimetidine, quinolone antibiotics, the Parkinson's drug levodopa, lithium, metformin, or drink alcohol regularly.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product is marketed as a muscle-building amino acid supplement with caffeine for workout performance. It's designed for people hitting the gym who want amino acid and energy support.

Before you start, check your medications — especially if you take seizure drugs, antihypertensive drugs, lithium, metformin, any antipsychotics or stomach acid medication, or antibiotics. Anyone taking ephedrine should absolutely avoid this product.

Talk to your pharmacist or doctor before adding it to your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 7 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Amino Build SX-7 Revolution White Raspberry Freezie, straight from the product label.

Brand MuscleTech
Barcode (UPC) 631656713305
Net contents 12.91 Ounce(s); 366 Gram(s)
Market status On market
Date entered into DSLD Jan 22, 2022
DSLD ID 258516
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Amino Build SX-7 Revolution White Raspberry Freezie by MuscleTech, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
19 Gram(s)
Maximum serving Sizes:
19 Gram(s)
Servings per container
20
UPC/BARCODE
631656713305
IngredientAmount% DV
Calories60 Calorie(s)--
L-Glutamine1 Gram(s)--
Vitamin B610 mg--
L-Isoleucine2.5 Gram(s)--
L-Valine2.5 Gram(s)--
Vitamin B1212 mcg--
Betaine Anhydrous2.5 Gram(s)--
Taurine2 Gram(s)--
2:1:1 Micro-BCAA Complex Matrix0 NP--
L-Leucine5 Gram(s)--
Intravol Musclebuilding Matrix0 NP--
Durian200 mg--
NeuroSphere Energy & Focus Matrix0 NP--
Caffeine100 mg--
Japanese Raisin Tree extract50 mg--

Other ingredients: Citric Acid, Natural and Artificial flavors, Malic Acid, Silicon Dioxide, Sucralose, Acesulfame Potassium

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Explosive energy Enhanced focus Increased strength Superior performance

Made in the U.S.A. from international ingredients.

Amino Build SX-7 Revolution features advanced, dual-phase ActivSphere technology and delivers full clinical doses of key ingredients for muscle growth, strength and performance. This exclusive formula was developed to provide immediate and long-lasting energy while also supporting muscle recovery and maximum muscle growth and performance!

Energy Focus Performance

Formula

L-leucine, Activsphere L-leucine & Pepform L-leucine peptides A precise combination of three types of leucine – the most anabolic amino acid for superior protein synthesis. Our 5 g dose of leucine is best-in-class. L-isoleucine & L-valine An additional 5 g of isoleucine and valine designed to support protein synthesis and muscle repair. L-glutamine The most abundant conditionally essential amino acid in your body. It helps support increased cell volume, glycogen replenishment and protein synthesis. Betaine Each scoop delivers a precise 2.5 g dose of betaine, shown to build 3.75 lbs of lean muscle in 6 weeks compared to 0.66 lbs by the placebo group. That’s over 5.5 times the muscle gained (vs. placebo). Betaine has also been shown in a separate study to enhance muscle endurance. Dual-phase caffeine A revolutionary combination of immediate- and sustained-release caffeine to enhance focus and to boost energy and intensity. Taurine A potent 2 g dose of taurine shown to improve performance in endurance athletes.

Performance-enhancing amino-BCAA formula A potent 10 g dose of BCAAs, supplying a clinically validated 5 g dose of L-leucine from three innovative sources – instantized L-leucine, ActivSphere L-leucine and PepForm L-leucine peptides. They work synergystically for powerful anabolic effects. The formula also features a clinical dose of taurine shown to improve performance in endurance athletes. + Powerful musclebuilding ingredients That powerful dose of leucine also works with a scientifically researched dose of betaine for increased strength, lean muscle and enhanced muscle endurance. + Instant & long-lasting energy Delivers a dual-phase combination of instant-release caffeine plus sustained-release caffeine for a powerful boost in energy, focus and intensity. = Amino Build SX-7 Revolution ultimate amino + energy The most advanced musclebuilding BCAA formula, featuring clinically dosed betaine, powerful cell volumizers and dual-phase caffeine for enhanced energy, uncompromising power and more explosive workouts!

Ultimate BCAA + energy

20 servings White raspberry freeze Natural and artificial flavor

One serving of this product contains up to as much caffeine as 1 cup of coffee.

General Statements

Twitter @MuscleTech Instagram MuscleTech Facebook Like us on Facebook

MuscleTech is America’s #1 Selling Bodybuilding Supplement Brand based on cumulative wholesale dollar sales 2001 to present.

MuscleTech research & development Technology meets efficacy without compromise

New & improved formula! America's #1 selling bodybuilding supplement brand

Dual-phase ActivSphere technology

Brand IP Statement(s)

LEU PepForm PepForm is a trademark of Glanbia plc.

Copyright 2018.

FDA Statement of Identity

Dietary Supplement

Precautions

Contains milk and soy ingredients. Processed in a facility that also processes wheat, egg, peanut, tree nut, fish and shellfish ingredients.

Warning: Not intended for use by persons under 18.

Do not use if pregnant or nursing.

Consult a medical doctor before starting a diet or exercise program or if you have a medical condition.

One serving of this product contains up to as much caffeine as 1 cup of coffee. Caffeine-sensitive individuals may experience the following symptoms including (but not limited to) restlessness, nervousness, tremors, headache, anxiety, palpitations, increased heart rate or difficulty sleeping. Do not combine with other sources of caffeine.

Keep out of reach of children.

Do not use if packaging has been tampered with.

Suggested/Recommended/Usage/Directions

Directions: Mix 1 serving (1 scoop) with 12 oz of water and consume pre- and intra workout. Read the entire label before use and follow directions provided. Do not exceed 1 scoop in a 24-hour period. If you want to add to your overall daily BCAA intake without the additional calories from drinking multiple protein shakes, you can also add 1 scoop to a jug of water and drink it over time.

Storage

Store in a cool, dry place (60 degrees F to 80 degrees F).

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Amino Build SX-7 Revolution White Raspberry Freezie by MuscleTech label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Amino Build SX-7 Revolution White Raspberry Freezie label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Amino Build SX-7 Revolution White Raspberry Freezie by MuscleTech

These are the 11 active ingredients this product is made of. Select any to open its full monograph.

Serving size19 Gram(s) Dosage formPowder Servings per container20 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin B6

Interacts with
210 drugs
10 mg per serving Form: Pyridoxine Hydrochloride

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vitamin B6 monograph & interactions

Vitamin B12

Interacts with
20 drugs
12 mcg per serving Form: Methylcobalamin

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very h...

Vitamin B12 monograph & interactions

2:1:1 Micro-BCAA Complex Matrix

0 NP per serving
  • › L-Isoleucine
  • › L-Valine
  • › L-Leucine

Intravol Musclebuilding Matrix

0 NP per serving

NeuroSphere Energy & Focus Matrix

0 NP per serving
  • › Caffeine
  • › Japanese Raisin Tree extract

Other (inactive) ingredients: Citric Acid, Natural and Artificial flavors, Malic Acid, Silicon Dioxide, Sucralose, Acesulfame Potassium. These complete the product’s ingredient list but are not active constituents.

Interaction report

Amino Build SX-7 Revolution White Raspberry Freezie by MuscleTech Drug Interactions

Want to check YOUR meds against Amino Build SX-7 Revolution White Raspberry Freezie?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
781Drugs
8 Major 609 Moderate 164 Minor

Ingredients driving the most interactions

Caffeine 655
Vitamin B6 210
Taurine 173
L-Glutamine 50
Vitamin B12 20

Individual Drug Interactions

The ingredients in Amino Build SX-7 Revolution White Raspberry Freezie interact with 781 drugs. Click any drug to see the details.

6 of the 11 ingredients in Amino Build SX-7 Revolution White Raspberry Freezie interact with drugs. Each result below shows which ingredient is responsible. Caffeine Vitamin B6 Taurine L-Glutamine Vitamin B12 Durian

Each ingredient & the kinds of drugs it affects

For each ingredient in Amino Build SX-7 Revolution White Raspberry Freezie with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Caffeine41 drug types · 655 drugs

Ephedrine

Theoretically, concomitant use might increase the risk for stimulant adverse effects.
Use of ephedrine with caffeine can increase the risk of stimulatory adverse effects. There is evidence that using ephedrine with caffeine might increase the risk of serious life-threatening or debilitating adverse effects such as hypertension, myocardial infarction, stroke, seizures, and death.

Likelihood Probable Evidence D
Adenosine (Adenocard)

Theoretically, caffeine might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Some evidence shows that caffeine is a competitive inhibitor of adenosine and can reduce the vasodilatory effects of adenosine in humans. However, other research shows that caffeine does not seem to affect supplemental adenosine because high interstitial levels of adenosine overcome the antagonistic effects of caffeine. It is recommended that methylxanthines and methylxanthine-containing products be stopped 24 hours prior to pharmacological stress tests. However, methylxanthines appear more likely to interfere with dipyridamole (Persantine) than adenosine-induced stress testing.

Likelihood Possible Evidence B
Anticoagulant/Antiplatelet Drugs

Theoretically, caffeine may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Caffeine is reported to have antiplatelet activity. Theoretically, it might increase the risk of bleeding when used concomitantly with these agents; however, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Beta-Adrenergic Agonists

Theoretically, large amounts of caffeine might increase the cardiac inotropic effects of beta-agonists.

Likelihood Probable Evidence D
Carbamazepine (Tegretol)

Theoretically, caffeine might reduce the effects of carbamazepine and increase the risk for convulsions.
Animal research suggests that taking caffeine can lower the anticonvulsant effects of carbamazepine and can induce seizures when taken in doses above 400 mg/kg. Human research has shown that taking caffeine 300 mg in three divided doses along with carbamazepine 200 mg reduces the bioavailability of carbamazepine by 32% and prolongs the plasma half-life of carbamazepine 2-fold in healthy individuals.

Likelihood Possible Evidence D
Cimetidine (Tagamet)

Theoretically, cimetidine might increase the levels and adverse effects of caffeine.
Cimetidine decreases the rate of caffeine clearance by 31% to 42%.

Likelihood Likely Evidence B
Clozapine (Clozaril)

Caffeine might increase the levels and adverse effects of clozapine and acutely exacerbate psychotic symptoms.
Caffeine might increase the effects and toxicity of clozapine. Caffeine doses of 400-1000 mg per day inhibit clozapine metabolism. Clozapine is metabolized by cytochrome P450 1A2 (CYP1A2). Although researchers speculate that caffeine might inhibit CYP1A2, there is no reliable evidence that caffeine affects CYP1A2. There is also speculation that genetic factors might make some patients more sensitive to an interaction between clozapine and caffeine. In one case report, severe, life-threatening clozapine toxicity and multiorgan system failure occurred in a patient with schizophrenia stabilized on clozapine who consumed caffeine 600 mg daily.

Likelihood Possible Evidence B
Dipyridamole (Persantine)

Theoretically, caffeine might decrease the vasodilatory effects of dipyridamole and interfere with its use prior to stress testing.
Caffeine inhibits dipyridamole-induced vasodilation. It is recommended that methylxanthines and methylxanthine-containing products be stopped 24 hours prior to pharmacological stress tests. Methylxanthines appear more likely to interfere with dipyridamole (Persantine) than adenosine-induced stress testing.

Likelihood Probable Evidence B
Disulfiram (Antabuse)

Theoretically, disulfiram use might increase the levels and adverse effects of caffeine.
Disulfiram decreases the rate of caffeine clearance.

Likelihood Probable Evidence B
Diuretic Drugs

Theoretically, using caffeine with diuretic drugs might increase the risk of hypokalemia.
Caffeine, especially in excessive amounts, can reduce potassium levels due to stimulation of the sodium-potassium pump. Diuretics can also cause lower potassium levels.

Likelihood Possible Evidence D
Estrogens

Theoretically, estrogens might increase the levels and adverse effects of caffeine.
Estrogen inhibits caffeine metabolism.

Likelihood Probable Evidence B
Ethosuximide (Zarontin)

Theoretically, caffeine might reduce the effects of ethosuximide and increase the risk for convulsions.
Animal research suggests that caffeine 92.4 mg/kg can decrease the anticonvulsant activity of ethosuximide. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Felbamate (Felbatol)

Theoretically, caffeine might reduce the effects of felbamate and increase the risk for convulsions.
Animal research suggests that a high dose of caffeine 161.7 mg/kg can decreases the anticonvulsant activity of felbamate. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Flutamide (Eulexin)

Theoretically, caffeine might increase the levels and adverse effects of flutamide.
In vitro evidence suggests that caffeine can inhibit the metabolism of flutamide. However, this effect has not been reported in humans.

Likelihood Probable Evidence D
Fluvoxamine (Luvox)

Theoretically, fluvoxamine might increase the levels and adverse effects of caffeine.
Fluvoxamine reduces caffeine metabolism.

Likelihood Probable Evidence D
Lithium

Abrupt caffeine withdrawal might increase the levels and adverse effects of lithium.
Caffeine has diuretic activity. When abruptly discontinued, caffeine may alter the clearance of lithium. There are two case reports of lithium tremor that worsened upon abrupt coffee withdrawal and 6 case reports of elevated serum lithium levels after reducing or eliminating caffeine intake. In one case, a male with schizoaffective disorder stabilized on lithium had an elevated lithium level after reducing his caffeine intake by 87%. At a later date, he increased his caffeine intake by 6-fold, resulting in a subtherapeutic lithium level and a recurrence of psychiatric symptoms.

Likelihood Probable Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, concomitant use might increase the risk of a hypertensive crisis.
Caffeine has been shown to inhibit monoamine oxidase (MAO) A and B in laboratory studies. Concomitant intake of large amounts of caffeine with MAOIs might precipitate a hypertensive crisis. In a case report, a patient that consumed 10-12 cups of caffeinated coffee and took the MAOI tranylcypromine presented with severe hypertension. Hypertension was resolved after the patient switched to drinking decaffeinated coffee.

Likelihood Possible Evidence D
Nicotine

Theoretically, concomitant use might increase the risk of hypertension.
Concomitant use of caffeine and nicotine has been shown to have additive cardiovascular effects, including increased heart rate and blood pressure. Blood pressure was increased by 10.8/12.4 mmHg when the agents were used concomitantly.

Likelihood Probable Evidence B
Pentobarbital (Nembutal)

Theoretically, caffeine might decrease the effects of pentobarbital.
Caffeine might negate the hypnotic effects of pentobarbital.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

Theoretically, caffeine might reduce the effects of phenobarbital and increase the risk for convulsions.
Animal research suggests that caffeine can decrease the anticonvulsant activity of phenobarbital. However, the exact mechanism of this interaction is unclear.

Likelihood Possible Evidence D
Phenylpropanolamine

Theoretically, phenylpropanolamine might increase the risk of hypertension, as well as the levels and adverse effects of caffeine.
Concomitant use of phenylpropanolamine and caffeine might cause an additive increase in blood pressure. Phenylpropanolamine also seems to increase caffeine serum levels.

Likelihood Probable Evidence B
Phenytoin (Dilantin)

Theoretically, caffeine might reduce the effects of phenytoin and increase the risk for convulsions.
Animal research suggests that caffeine can decrease the anticonvulsant activity of phenytoin. The effect does not seem to be related to the seizure threshold-lowering effects of caffeine. However, the exact mechanism of this interaction is unclear.

Likelihood Possible Evidence D
Pioglitazone (Actos)

Theoretically, caffeine might increase the levels and clinical effects of pioglitazone.
Animal research suggests that caffeine can modestly increase the maximum concentration, area under the curve, and half-life of pioglitazone, and also reduce its clearance. This increased the antidiabetic effects of pioglitazone. However, the exact mechanism of this interaction is unclear.

Likelihood Possible Evidence D
Quinolone Antibiotics

Theoretically, quinolone antibiotics might increase the levels and adverse effects of caffeine.
Quinolones (also called fluoroquinolones) can decrease caffeine clearance by inhibiting cytochrome P450 1A2 (CYP1A2) enzyme.

Likelihood Probable Evidence B
Riluzole (Rilutek)

Theoretically, concomitant use might increase the levels and adverse effects of both caffeine and riluzole.
Caffeine and riluzole are both metabolized by cytochrome P450 1A2 (CYP1A2), and concomitant use might reduce the metabolism of one or both agents.

Likelihood Possible Evidence D
Caffeine full monograph & all 41 interactions

Vitamin B65 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D
Vitamin B6 full monograph & interactions

Taurine2 drug types · 173 drugs

Antihypertensive Drugs

Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Some clinical evidence suggests that taurine can reduce both systolic and diastolic blood pressure.

Likelihood Probable Evidence D
Lithium

Theoretically, taurine might reduce excretion and increase plasma levels of lithium.
Taurine is thought to have diuretic properties, which might reduce the excretion of lithium.

Likelihood Probable Evidence D
Taurine full monograph & interactions

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions

Vitamin B121 drug type · 20 drugs

Metformin (Glucophage)

Metformin, a common medication used to manage type 2 diabetes, has been associated with lower vitamin B12 levels in some individuals. Prolonged use of metformin can interfere with the absorption of B12 in the digestive system, potentially leading to a deficiency in this essential vitamin.

Likelihood Possible Evidence A
Vitamin B12 full monograph & interactions

Durian1 drug type · 1 drug

Alcohol (Ethanol)

There is a traditional belief that ingestion of alcohol with durian can be fatal. A case report from 1941 describes an adult in India who developed acute hemorrhagic pancreatitis and died after drinking alcohol with durian, but there have been no other published reports since. A study in mice given homogenized durian fruit flesh in 10% ethanol did not demonstrate any toxicity. However, evidence from in vitro research shows that durian extract can inhibit alcohol dehydrogenase. This activity is similar to the effects of disulfiram. In theory, concomitant use might cause effects similar to disulfiram-ethanol reactions. Until more is known, avoid concomitant use of durian and alcohol.

Likelihood Possible Evidence D
Durian full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Amino Build SX-7 Revolution White Raspberry Freezie, from the product label.

MuscleTech

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Name
Iovate Health Sciences U.S.A. Inc.
Street Address
1105 North Market Street, Suite 1330
City
Wilmington
State
DE
ZipCode
19801
Web Address
muscletech.com
Pharmacist Counseling Corner

Amino Build SX-7 Revolution White Raspberry Freezie by MuscleTech: Common Questions

Does Amino Build SX-7 Revolution White Raspberry Freezie by MuscleTech interact with any medications?
Yes. Based on its ingredients, Amino Build SX-7 Revolution White Raspberry Freezie has a known interaction with 781 medications, including 8 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Amino Build SX-7 Revolution White Raspberry Freezie contains 11 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help me build muscle?
The amino acids in this product are designed to support muscle building and recovery, especially around workouts. Glutamine, the BCAAs (leucine, isoleucine, valine), and taurine all play roles in muscle metabolism. The evidence is strongest for glutamine in recovery after surgery or critical illness, and for the BCAAs during intense training — but we don't have direct data on this complete formulation as a whole.
Is it safe if I'm pregnant?
Glutamine data shows insufficient information for pregnancy — there's not enough to say yes or no — so talk with your doctor or pharmacist. Vitamin B6 is possibly unsafe at high doses in pregnancy, though normal amounts are fine. Vitamin B12 is safe and actually needed in pregnancy. Caffeine is possibly safe but possibly unsafe — your doctor can advise on safe limits. Because of these mixed signals, check with your provider before using this product while pregnant.
Can I take this while breastfeeding?
Glutamine and betaine lack reliable safety data for breastfeeding, so avoid unless your clinician advises otherwise. Vitamin B12 is safe and important during breastfeeding. Caffeine does pass into breast milk in small amounts and is usually fine at moderate intake, but high amounts can affect your baby. Taurine is likely safe as a food source but supplement safety isn't well studied. Talk with your doctor before starting this product.
What's the caffeine content?
The product facts don't specify how much caffeine is in each serving. That's important to know, especially if you're also drinking coffee or taking other caffeine products — too much can cause jitteriness, insomnia, headache, and other side effects. Check the label or contact the manufacturer for the exact amount.
What are BCAAs and why are they in here?
BCAAs — branched-chain amino acids — are leucine, isoleucine, and valine. Your body uses them to build and repair muscle. They're popular in workout supplements because they may help reduce muscle breakdown during intense training and support recovery. This product includes them as individual ingredients and also in a proprietary 2:1:1 BCAA blend.
Are there any fillers or other ingredients I should know about?
The six inactive ingredients are citric acid, natural and artificial flavors, malic acid, silicon dioxide, sucralose, and acesulfame potassium — these are the fillers, sweeteners, and flavor components common in powdered supplements. The product also contains proprietary blend matrices whose full ingredient lists aren't detailed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Amino Build SX-7 Revolution White Raspberry Freezie label
Go deeper

The Full Monographs Behind Amino Build SX-7 Revolution White Raspberry Freezie’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin B6

Interacts with 210 drugs

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...

Read the full Vitamin B6 monograph → Herb & supplement monograph

Vitamin B12

Interacts with 20 drugs

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very helpful for people who are deficient — su...

Read the full Vitamin B12 monograph → Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph → Herb & supplement monograph

Betaine Anhydrous

Betaine anhydrous (also called trimethylglycine) is a compound found in foods like beets, spinach, and whole grains, and is sold as a supplement and as a prescription medicine for a rare gen...

Read the full Betaine Anhydrous monograph → Herb & supplement monograph

Taurine

Interacts with 173 drugs

Taurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements, and short-term use appears generally sa...

Read the full Taurine monograph → Herb & supplement monograph

Durian

Interacts with 1 drug

Durian is a popular tropical fruit valued mainly as a nutritious food rich in carbohydrates, fiber, vitamins, and antioxidants. While it has many traditional medicinal uses, there is little...

Read the full Durian monograph → Herb & supplement monograph

Caffeine

Interacts with 655 drugs

Caffeine is a natural stimulant found in coffee, tea, and many other plants and products. In moderate amounts it can boost alertness and reduce tiredness for most healthy adults, but too muc...

Read the full Caffeine monograph →
Sources

Sources & How We Checked

Amino Build SX-7 Revolution White Raspberry Freezie's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 346 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
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  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Vitamin B6 32 references
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  16. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
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  18. Hatzitolios, A., Iliadis, F., Katsiki, N., and Baltatzi, M. Is the anti-hypertensive effect of dietary supplements via aldehydes reduction evidence based? A systematic review. Clin Exp.Hypertens. 2008;30(7):628-639. PubMed
  19. Vasdev, S., Ford, C. A., Parai, S., Longerich, L., and Gadag, V. Dietary vitamin B6 supplementation attenuates hypertension in spontaneously hypertensive rats. Mol.Cell Biochem. 1999;200(1-2):155-162.
  20. de, Vogel S., Dindore, V., van, Engeland M., Goldbohm, R. A., van den Brandt, P. A., and Weijenberg, M. P. Dietary folate, methionine, riboflavin, and vitamin B-6 and risk of sporadic colorectal cancer. J Nutr 2008;138(12):2372-2378. PubMed
  21. Hagen, I., Nesheim, B. I., and Tuntland, T. No effect of vitamin B-6 against premenstrual tension. A controlled clinical study. Acta Obstet.Gynecol.Scand. 1985;64(8):667-670. PubMed
  22. Aybak, M., Sermet, A., Ayyildiz, M. O., and Karakilcik, A. Z. Effect of oral pyridoxine hydrochloride supplementation on arterial blood pressure in patients with essential hypertension. Arzneimittelforschung. 1995;45(12):1271-1273.
  23. Lal, K. J., Dakshinamurti, K., and Thliveris, J. The effect of vitamin B6 on the systolic blood pressure of rats in various animal models of hypertension. J Hypertens. 1996;14(3):355-363. PubMed
  24. Lauritzen CH, Reuter HD, Repges R, Bohnert K, and Schmidt U. Treatment of premenstrual tension syndrome with Vitex agnus castus. Controlled, double-blind study versus pyridoxine. Phytomed 1997;4(3):183-189. PubMed
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  27. Hoyer-Kuhn H, Kohbrok S, Volland R, Franklin J, Hero B, Beck BB, Hoppe B. Vitamin B6 in primary hyperoxaluria I: first prospective trial after 40 years of practice. Clin J Am Soc Nephrol. 2014 Mar;9(3):468-77. PubMed
  28. Mahmoud A, Tabassum S, Al Enazi S, et al. Amelioration of levetiracetam-induced behavioral side effects by pyridoxine. A randomized double blind controlled study. Pediatr Neurol 2021;119:15-21. PubMed
  29. Gupta M, Gallante B, Bamberger JN, et al. Prospective randomized evaluation of idiopathic hyperoxaluria treatments. J Endourol 2021;35(12):1844-1851. PubMed
  30. Li H, Chen M, Liang S, et al. Excessive vitamin B6 during treatment is related to poor prognosis of patients with nasopharyngeal carcinoma: A U-shaped distribution suggests low dose supplement. Clin Nutr 2021;40(4):2293-2300. PubMed
  31. Tanigawa J, Nabatame S, Tominaga K, et al. High-dose pyridoxine treatment for inherited glycosylphosphatidylinositol deficiency. Brain Dev 2021;43(6):680-687. PubMed
  32. Committee on Practice Bulletins-Obstetrics. ACOG Practice Bulletin No. 189: Nausea And Vomiting Of Pregnancy. Obstet Gynecol. 2018;131(1):e15-e30. PubMed

See these in context on the Vitamin B6 monograph →

Vitamin B12 30 references
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  2. Hartman TJ, Woodson K, Stolzenberg-Solomon R, et al. Association of the B-vitamins pyridoxal 5'-phosphate (B6), B12, and folate with lung cancer risk in older men. Am J Epidemiol 2001;153:688-94.. DOI
  3. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  4. Lange H, Suryapranata H, De Luca G, et al. Folate therapy and in-stent restenosis after coronary stenting. N Engl J Med 2004;350:2673-81. PubMed
  5. Collin, S. M., Metcalfe, C., Refsum, H., Lewis, S. J., Zuccolo, L., Smith, G. D., Chen, L., Harris, R., Davis, M., Marsden, G., Johnston, C., Lane, J. A., Ebbing, M., Bonaa, K. H., Nygard, O., Ueland, P. M., Grau, M. V., Baron, J. A., Donovan, J. L., Nea
  6. Geissbuhler, P., Mermillod, B., and Rapin, C. H. Elevated serum vitamin B12 levels associated with CRP as a predictive factor of mortality in palliative care cancer patients: a prospective study over five years. J.Pain Symptom.Manage. 2000;20(2):93-103. PubMed
  7. Salles, N., Herrmann, F., Sakbani, K., Rapin, C. H., and Sieber, C. High vitamin B12 level: a strong predictor of mortality in elderly inpatients. J Am Geriatr.Soc 2005;53(5):917-918.
  8. Looker, H. C., Fagot-Campagna, A., Gunter, E. W., Pfeiffer, C. M., Sievers, M. L., Bennett, P. H., Nelson, R. G., Hanson, R. L., and Knowler, W. C. Homocysteine and vitamin B(12) concentrations and mortality rates in type 2 diabetes. Diabetes Metab Res R
  9. Uhl, W., Nolting, A., Golor, G., Rost, K. L., and Kovar, A. Safety of hydroxocobalamin in healthy volunteers in a randomized, placebo-controlled study. Clin Toxicol (Phila) 2006;44 Suppl 1:17-28. PubMed
  10. Borron, S. W., Baud, F. J., Barriot, P., Imbert, M., and Bismuth, C. Prospective study of hydroxocobalamin for acute cyanide poisoning in smoke inhalation. Ann Emerg.Med 2007;49(6):794-801, 801. PubMed
  11. Borron, S. W., Baud, F. J., Megarbane, B., and Bismuth, C. Hydroxocobalamin for severe acute cyanide poisoning by ingestion or inhalation. Am J Emerg.Med 2007;25(5):551-558. PubMed
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  16. Aalfs As, Scholvinck LH, Horvath B. Acneiform eruption in a 5-year old due to vitamin B12 supplementation. Eur J Dermatol 2013;23(5):726-7. PubMed
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See these in context on the Vitamin B12 monograph →

Betaine Anhydrous 11 references
  1. Cystadane (betaine anhydrous for oral solution) Package insert. Orphan Medical, Inc. Minnetonka, MN. November 2005.
  2. Abdelmalek MF, Angulo P, Jorgensen RA, et al. Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study. Am J Gastroenterol 2001;96:2711-7.. PubMed
  3. Schwab U, Torronen A, Toppinen L, et al. Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects. Am J Clin Nutr 2002;76:961-7. PubMed
  4. McGregor DO, Dellow WJ, Robson RA, et al. Betaine supplementation decreases post-methionine hyperhomocysteinemia in chronic renal failure. Kidney Int 2002;61:1040-6. PubMed
  5. Olthof MR, van Vliet T, Verhoef P, et al. Effect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humans. PloS Med 2005;2:e135. PubMed
  6. Knopman, D. and Patterson, M. An open-label, 24-week pilot study of the methyl donor betaine in Alzheimer disease patients. Alzheimer Dis.Assoc.Disord. 2001;15(3):162-165. PubMed
  7. Moat, S. J., Madhavan, A., Taylor, S. Y., Payne, N., Allen, R. H., Stabler, S. P., Goodfellow, J., McDowell, I. F., Lewis, M. J., and Lang, D. High- but not low-dose folic acid improves endothelial function in coronary artery disease. Eur J Clin Invest 2 PubMed
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  10. Zawieja EE, Zawieja B, Chmurzynska A. Betaine supplementation moderately increases total cholesterol levels: a systematic review and meta-analysis. J Diet Suppl. 2021;18(1):105-117. PubMed
  11. Imbard A, Toumazi A, Magréault S, et al. Efficacy and pharmacokinetics of betaine in CBS and cblC deficiencies: a cross-over randomized controlled trial. Orphanet J Rare Dis 2022;17(1):417. PubMed

See these in context on the Betaine Anhydrous monograph →

Taurine 21 references
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  2. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  3. Obermann M, Schorn CF, Mummel P, et al. Taurine induced toxic encephalopathy? Clin Neurol Neurosurg 2006;108:812-3. PubMed
  4. Bichler, A., Swenson, A., and Harris, M. A. A combination of caffeine and taurine has no effect on short term memory but induces changes in heart rate and mean arterial blood pressure. Amino Acids 2006;31(4):471-476. PubMed
  5. Iyadurai, S. J. and Chung, S. S. New-onset seizures in adults: possible association with consumption of popular energy drinks. Epilepsy Behav 2007;10(3):504-508. PubMed
  6. Berger, A. J. and Alford, K. Cardiac arrest in a young man following excess consumption of caffeinated "energy drinks". Med J Aust. 1-5-2009;190(1):41-43. PubMed
  7. Worthley, M. I., Prabhu, A., De, Sciscio P., Schultz, C., Sanders, P., and Willoughby, S. R. Detrimental effects of energy drink consumption on platelet and endothelial function. Am J Med 2010;123(2):184-187. PubMed
  8. Morchon, Simon D. and Perez Castrillon, J. L. [Hypoglycemia by intake of taurine]. Rev.Clin Esp. 2010;210(1):49.
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  11. Calabro, R. S., Italiano, D., Gervasi, G., and Bramanti, P. Single tonic-clonic seizure after energy drink abuse. Epilepsy Behav 2012;23(3):384-385. PubMed
  12. Fujita, T., Ando, K., Noda, H., Ito, Y., and Sato, Y. Effects of increased adrenomedullary activity and taurine in young patients with borderline hypertension. Circulation 1987;75(3):525-532. PubMed
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  15. Franconi, F., Bennardini, F., Mattana, A., Miceli, M., Ciuti, M., Mian, M., Gironi, A., Anichini, R., and Seghieri, G. Plasma and platelet taurine are reduced in subjects with insulin-dependent diabetes mellitus: effects of taurine supplementation. Am.J. DOI
  16. Stohs SJ, Miller M. A case study involving allergic reactions to sulfur-containing compounds including, sulfite, taurine, acesulfame potassium and sulfonamides. Food Chem Toxicol. 2014 Jan;63:240-3. PubMed
  17. Sun Q, Wang B, Li Y, Sun F, et al. Taurine supplementation lowers blood pressure and improves vascular function in prehypertension: randomized, double-blind, placebo-controlled study. Hypertension 2016 Mar;67(3):541-9. PubMed
  18. Jang ES, Hwang SH, Kim JW, Jeong SH. Effectiveness of 4-week oral taurine treatment for muscle cramps in patients with liver cirrhosis: a single-arm pilot study. Yonsei Med J 2021;62(1):21-8. PubMed
  19. Guan L, Miao P. The effects of taurine supplementation on obesity, blood pressure and lipid profile: A meta-analysis of randomized controlled trials. Eur J Pharmacol 2020;885:173533. PubMed
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