Major interaction on record — check this product against your medications before combining. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

AnaBeta Elite Ingredients & Drug Interactions

by P E Science

Capsule Category: Botanical
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

AnaBeta Elite is a dietary supplement by P E Science with 4 active ingredients. Its ingredients are commonly taken for toothache and oral discomfort, increasing saliva flow, sluggish digestion.Based on those ingredients, 915 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Coleus forskohlii. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of AnaBeta Elite by P E Science

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.
  • “AnaBeta Elite Proprietary Blend” is a proprietary blend — the label gives one combined amount (3,000 mg) without saying how much of each component you get.

AnaBeta Elite contains 4 active ingredients, listed as a proprietary blend plus three individual extracts. The blend includes Lodhra (bark), Anacyclus Pyrethrum (root), and Cistanche deserticola (stem) — traditional plant materials — along with Coleus forskohlii, which contains a compound called forskolin that research suggests may affect blood pressure and how your body processes certain drugs.

The capsule also holds inactive ingredients: gelatin, silicon dioxide, magnesium stearate, and two food colorings (FD&C Blue #1 and FD&C Red #40).

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We hold no effectiveness data for the three traditional plant ingredients — Lodhra, Anacyclus Pyrethrum, and Cistanche deserticola. For Coleus forskohlii, the evidence we have is insufficient to rate its use for any condition, including angina, asthma, cancer, heart failure, eczema, or dry eye.

That means clinical studies haven't established reliable proof that it works for these purposes.

The evidence, ingredient by ingredient Pellitory Cistanche Deserticola Coleus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Coleus is generally well tolerated when taken by mouth, though some people in trials reported dose-related gastrointestinal side effects — chiefly diarrhea, nausea, and constipation — at modest rates. It may lower blood pressure and isn't well studied for long-term use, so use requires care and professional guidance.

The data advise against coleus during pregnancy and breastfeeding. Anacyclus Pyrethrum has limited safety data and may cause mouth irritation or allergic reactions; Cistanche deserticola is generally tolerated in traditional use but human safety data are thin.

The safety information for Lodhra is not on file. Neither Anacyclus Pyrethrum nor Cistanche deserticola should be used during pregnancy or breastfeeding, per the available data.

Side effects, ingredient by ingredient Pellitory Cistanche Deserticola Coleus

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 3 matched ingredients can interact with medications — Coleus.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 916 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking AnaBeta Elite, double-check with your pharmacist or doctor if you're on nitrates or calcium channel blockers for your heart — Coleus carries Major-severity interactions with both. Also verify if you take blood pressure medications, blood thinners (including warfarin), or any drugs that depend on liver enzymes CYP2C9 or CYP3A4 for clearance, since Coleus has Moderate-severity interactions with each.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

AnaBeta Elite is built around Coleus forskohlii, an ingredient with major interactions affecting heart and blood pressure medications. If you take nitrates, calcium channel blockers, blood pressure drugs, blood thinners, or any medication metabolized by your liver, you need to check with your pharmacist or doctor before starting this product.

The other ingredients lack robust evidence for their effectiveness and carry their own pregnancy and breastfeeding cautions.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about AnaBeta Elite, straight from the product label.

Brand P E Science
Barcode (UPC) 040232199264
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2016
DSLD ID 56654
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for AnaBeta Elite by P E Science, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Capsule(s)
Maximum serving Sizes:
4 Capsule(s)
Servings per container
30
UPC/BARCODE
040232199264
IngredientAmount% DV
AnaBeta Elite Proprietary Blend3000 mg--
Lodhra (bark) extract0 NP--
Anacyclus Pyrethrum D.C. (root) extract0 NP--
Cistanche deserticola (stem) extract0 NP--
Coleus forskohlii0 NP--

Other ingredients: Gelatin, Silicon Dioxide, Magnesium Stearate, FD&C Blue #1, FD&C Red #40

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take 4 capsules daily. For best results, take 2 capsules with each of your two largest meals each day.

Precautions

WARNING: This product is intended to be consumed by healthy adults 18 years of age or older.

Pregnant or nursing women should not use this product. Consult with a licensed physician before using this product, especially if you are taking any prescription, over the counter medication, dietary supplement product, or if you have any preexisting medical condition including but not limited to: high or low blood pressure, high or low cholesterol, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, seizure disorder, psychiatric disease, osteoporosis, diabetes, difficulty urinating due to prostate enlargement or if you are taking a MAO-B inhibitor or any other medication.

Do not take this product if you have been diagnosed with prostate cancer, testicular cancer or breast cancer. Discontinue use 2 weeks prior to surgery. Discontinue use and immediately consult your health care professional if you experience any adverse reaction to this product. Do not exceed recommended serving. Do not use if safety seal is broken or missing

Keep out of reach of children.

Formula

It is designed for individuals interested in bodybuilding who generally do not have health problems.

~ With CistaMAX ~ Anacyclus Extract

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

30 Day Supply 4 Powerful Ingredients 4 Capsules Per Day

Bulking Agent Formulated for mass ~ Designed for bulking diets

~ 30-Day Supply

{Capsule} Not actual size

FDA Statement of Identity

Dietary Supplement

See for yourself

AnaBeta Elite by P E Science label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in AnaBeta Elite by P E Science

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size4 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

AnaBeta Elite Proprietary Blend

3000 mg per serving

Other (inactive) ingredients: Gelatin, Silicon Dioxide, Magnesium Stearate, FD&C Blue #1, FD&C Red #40. These complete the product’s ingredient list but are not active constituents.

Interaction report

AnaBeta Elite by P E Science Drug Interactions

Want to check YOUR meds against AnaBeta Elite?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
915Drugs
29 Major 886 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in AnaBeta Elite with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Coleus forskohlii7 drug types · 915 drugs

Calcium Channel Blockers

Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Forskolin, a constituent of coleus, and calcium channel blockers both cause coronary vasodilatory effects.

Likelihood Probable Evidence B
Nitrates

Theoretically, combining coleus with nitrates might increase the coronary vasodilatory effects.
Forskolin, a constituent of coleus, and nitrates both cause coronary vasodilatory effects.

Likelihood Probable Evidence B
Anticoagulant/Antiplatelet Drugs

Theoretically, concomitant use of coleus and anticoagulant or antiplatelet drugs might increase the risk of bruising and bleeding.
In vitro and animal research shows that forskolin, a constituent of coleus, can inhibit platelet aggregation and adhesion.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Animal research shows that forskolin, a constituent of coleus, may lower blood pressure.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, taking coleus may affect drugs metabolized by CYP2C9 and increase the risk of adverse effects or reduce the effectiveness.
Research on the effect of coleus on CYP2C9 is conflicting. Some animal research shows that coleus extract can induce CYP2C9, while in vitro research shows that coleus can inhibit CYP2C9. Until more is known, advise patients that taking coleus might increase or decrease levels of drugs metabolized by CYP2C9.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
In vitro research shows that coleus can activate the nuclear receptor, pregnane X receptor (PXR), which results in increased expression of CYP3A4. Although the clinical significance of this is not known, use caution when considering concomitant use of coleus and other drugs affected by these enzymes.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, taking coleus may affect the metabolism of warfarin and increase the risk of adverse effects or reduce the effectiveness.
Some animal research shows that coleus extract can induce cytochrome P450 2C9 (CYP2C9), an enzyme that metabolizes warfarin. However, other in vitro research shows that coleus can inhibit CYP2C9. Theoretically, taking coleus with drugs metabolized by CYP2C9 might affect drug levels and the risk of adverse effects. Until more is known, advise patients that taking coleus might increase or decrease levels of warfarin.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for AnaBeta Elite, from the product label.

P E Science

See all P E Science products
Name
Physique Enhancing Science
Street Address
3665 East Bay Dr #204-155
City
Largo
State
FL
ZipCode
33771
Phone Number
888-885-0195
Web Address
PESCIENCE.COM
Pharmacist Counseling Corner

AnaBeta Elite by P E Science: Common Questions

Does AnaBeta Elite by P E Science interact with any medications?
Yes. Based on its ingredients, AnaBeta Elite has a known interaction with 915 medications, including 29 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
AnaBeta Elite contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take AnaBeta Elite if I'm pregnant or breastfeeding?
The data advise against Coleus forskohlii during pregnancy and breastfeeding — not enough safety information exists. Anacyclus Pyrethrum and Cistanche deserticola also carry "avoid" ratings for both. Talk with your doctor or pharmacist about whether this product is right for you in these periods.
What side effects might I experience from AnaBeta Elite?
Coleus can cause gastrointestinal upset — chiefly diarrhea, but also nausea, vomiting, or constipation — at modest rates. Anacyclus Pyrethrum may cause mouth or skin irritation or allergic reactions, though safety data are limited. Most people tolerate Coleus well when taken by mouth.
Does AnaBeta Elite actually work for muscle growth or performance?
We have no effectiveness data on file for the three traditional plant ingredients in this blend. For Coleus forskohlii, the evidence is insufficient to rate it for any condition — clinical studies haven't established reliable proof it works.
Why does the label list it as a proprietary blend?
The blend groups several ingredients together under one name. The individual components — Lodhra, Anacyclus Pyrethrum, and Cistanche deserticola — are listed separately in the full ingredient list, so you can see exactly what you're getting.
Is AnaBeta Elite safe to use long-term?
Coleus forskohlii may lower blood pressure and isn't well studied for long-term use, so the data say to use it with care and professional guidance. If you're considering this product for weeks or months, talk with your pharmacist about what the safety profile means for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if AnaBeta Elite is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

AnaBeta Elite label
Sources

Sources & How We Checked

AnaBeta Elite's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 19 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pellitory 1 reference
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

See these in context on the Pellitory monograph →

Cistanche Deserticola 2 references
  1. Herbs at a Glance — NIH NCCIH Source
  2. Herbs and Supplements — MedlinePlus Source

See these in context on the Cistanche Deserticola monograph →

Coleus 16 references
  1. Baumann G, Felix S, Sattelberger U, Klein G. Cardiovascular effects of forskolin (HL-362) in patients with idiopathic congestiv cardiomyopathy. A comparative study with dobutamine and sodium nitroprusside. J Cardiovasc Pharmacol 1990;16:93-100.
  2. Kramer W, Thormann J, Kindler M, Schlepper M. Effects of forskolin on left ventricular function in dilated cardiomyopathy. Arzneimittelforschung 1987;37:364-7.
  3. Bauer K, Dietersdorfer F, Kaspar S, et al. Pharmacodynamic effects of inhaled dry powder formulations of fenoterol and colforsin in asthma. Clin Pharmacol Ther 1993;53:76-83. PubMed
  4. Christenson JT, Thulesius O, Nazzal MM. The effect of forskolin on blood flow, platelet metabolism, aggregation and ATP release. Vasa 1995;24:56-61.
  5. Agarwal KC, Zielinski BA, Maitra RS. Significance of plasma adenosine in the antiplatelet activity of forskolin: potentiation by dipyridamole and dilazep. Thromb Haemost 1989;61:106-10. DOI
  6. Agarwal KC, Parks RE. Forskolin: a potential antimetastatic agent. Int J Cancer 1983;32:801-4. PubMed
  7. Almeida, F. C. and Lemonica, I. P. The toxic effects of Coleus barbatus B. on the different periods of pregnancy in rats. J Ethnopharmacol 2000;73(1-2):53-60. PubMed
  8. Ding, X. and Staudinger, J. L. Induction of drug metabolism by forskolin: the role of the pregnane X receptor and the protein kinase a signal transduction pathway. J Pharmacol Exp Ther 2005;312(2):849-856. PubMed
  9. Staudinger, J. L., Ding, X., and Lichti, K. Pregnane X receptor and natural products: beyond drug-drug interactions. Expert.Opin Drug Metab Toxicol 2006;2(6):847-857. PubMed
  10. van Hecke, E., Hindryckx, P., Geuns, J. M., and Devriese, E. Airborne contact dermatitis from coleus in a housewife. Contact Dermatitis 1991;25(2):128-129. PubMed
  11. Schlepper, M., Thormann, J., and Mitrovic, V. Cardiovascular effects of forskolin and phosphodiesterase-III inhibitors. Basic Res Cardiol 1989;84 Suppl 1:197-212. PubMed
  12. Dooms-Goossens, A., Borghijs, A., Degreef, H., Devriese, E. G., and Geuns, J. M. Airborne contact dermatitis to Coleus. Contact Dermatitis 1987;17(2):109-110. PubMed
  13. Lindner, E., Dohadwalla, A. N., and Bhattacharya, B. K. Positive inotropic and blood pressure lowering activity of a diterpene derivative isolated from Coleus forskohli: Forskolin. Arzneimittelforschung 1978;28(2):284-289.
  14. Loftus HL, Astell KJ, Mathai ML, et al. Coleus forskohlii Extract Supplementation in Conjunction with a Hypocaloric Diet Reduces the Risk Factors of Metabolic Syndrome in Overweight and Obese Subjects: A Randomized Controlled Trial. Nutrients. 2015;7(11): PubMed
  15. Yokotani K, Chiba T, Sato Y, et al. Hepatic cytochrome P450 mediates interaction between warfarin and Coleus forskohlii extract in vivo and in vitro. J Pharm Pharmacol. 2012;64(12):1793-801.
  16. Nishijima C, Chiba T, Sato Y, Umegaki K. Nationwide Online Survey Enables the Reevaluation of the Safety of Coleus forskohlii Extract Intake Based on the Adverse Event Frequencies. Nutrients. 2019;11(4). pii: E866. PubMed

See these in context on the Coleus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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