Anabolic Primer & Anti-Inflammatory Support Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Anabolic Primer & Anti-Inflammatory Support against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Anabolic Primer & Anti-Inflammatory Support is a dietary supplement by GNC Pro Performance AMP with 2 active ingredients. Its ingredients are commonly taken for blood sugar control, boosting breast milk supply, high cholesterol.Based on those ingredients, 389 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Fenugreek seed extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Anabolic Primer & Anti-Inflammatory Support by GNC Pro Performance AMP
Ask about any prescription or over-the-counter medication and we check it for interactions with Anabolic Primer & Anti-Inflammatory Support by GNC Pro Performance AMP — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Anabolic Primer & Anti-Inflammatory Support by GNC Pro Performance AMP
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains two active ingredients. Fenugreek seed extract is the one we have information on — it's used traditionally for sexual function, menstrual symptoms, and blood sugar support.
Palmitic Acid Monoethanolamide is the other active ingredient, but we don't have interaction or effectiveness data on file for it. The capsule also contains inactive ingredients: gelatin, cellulose, stearic acid, and silica.
Does it work?
Insufficient evidence
Fenugreek seed extract is rated possibly effective for sexual dysfunction and sexual arousal, as well as for dysmenorrhea (period pain) and diabetes support. That means the evidence suggests it may help with these concerns, but the data isn't conclusive.
We have no effectiveness information on file for Palmitic Acid Monoethanolamide.
How safe is it?
Well-documented data
Fenugreek seed is generally well tolerated when taken by mouth, but supplement doses may cause side effects. The most common ones are abdominal pain, bloating, diarrhea, indigestion, gas, low blood sugar (hypoglycemia), and nausea.
Rare but serious allergic reactions have occurred, including severe swelling (angioedema), airway constriction (bronchospasm), and anaphylaxis. If you're pregnant, the safety data advises against using medicinal amounts of fenugreek — it may affect the uterus and has caused unusual body odor in newborns exposed at delivery.
Fenugreek is often promoted to boost milk supply during breastfeeding, but the evidence is limited; talk with your doctor or pharmacist first.
Meds to double-check
Moderate interaction found
Check these with your pharmacist before taking this product: blood thinners (anticoagulants) and antiplatelet drugs like warfarin or clopidogrel, diabetes medications, metoprolol or other blood pressure drugs, phenytoin (Dilantin) or other seizure meds, theophylline for asthma, and sildenafil (Viagra) or similar erectile dysfunction drugs. All of these have Moderate severity interactions with fenugreek seed extract.
The bottom line
Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is for people looking to support sexual function, menstrual health, or blood sugar — but only if you're not on blood thinners, diabetes meds, heart medications, seizure drugs, asthma meds, or erectile dysfunction drugs. If you take any prescription medication, check it against this product with our tool before you start.
Talk to your pharmacist about whether it's right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 23, 2016.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Anabolic Primer & Anti-Inflammatory Support, straight from the product label.
| Brand | GNC Pro Performance AMP |
|---|---|
| Net contents | 30 Pak(s) |
| Market status | On market |
| Date entered into DSLD | Dec 23, 2016 |
| DSLD ID | 67311 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult Male (18-50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Anabolic Primer & Anti-Inflammatory Support by GNC Pro Performance AMP, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Palmitic Acid Monoethanolamide | 100 mg | -- |
| Fenugreek seed extract | 300 mg | -- |
Other ingredients: Gelatin, Cellulose, Stearic Acid, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Clinically researched Includes powerful sports multivitamin Increases strength better than ordinary creatine Features high-quality anabolic primers
Code 209011 EQG
Conforms to USP <2091> for weight. Meets USP <2040> disintegration.
Actual size
GNC Quality Commitment Since 1935, GNC has been the leader in the development of superior dietary supplements. Our products are produced using only fresh, high-quality ingredients and are manufactured under the strictest quality controls.
GNC Guarantee If you are not 100% completely satisfied, return the unused portion of the product with your receipt to a GNC store within 30 days. Our trained sales staff will either refund your purchase price or, if you prefer, assist you in finding a replacement product to help you live well.
Several high-quality formulas in one convenient pack for maximum training support that boosts power and improves performance.
Anabolic Primer & Anti-Inflammatory Support Features high-quality anabolic primers to help pack on mass combined with anti-inflammatory support. In a clinical study of 17 healthy young adults, muscle biopsy results revealed that GNC Pro Performance AMP Amplified Creatine 189 resulted in 189% greater muscle creatine uptake relative to benchmark amounts of ordinary creatine monohydrate powder.
When used in conjunction with regular resistance training.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take the contents of one packet daily with food.
Brand IP Statement(s)
Each pak contains: Anabolic Primer & Anti-Inflammatory Support
Precautions
Warning: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, under 18 years of age or have a medical condition.
Warning: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, under 18 years of age or have a medical condition.
Discontinue use two weeks prior to surgery.
Keep out of reach of children.
Formulation
No artificial colors, no artificial flavors, no wheat, gluten free, no dairy, yeast free.
Storage
Store in a cool, dry place.
Seals/Symbols
Gf Gluten free
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Anabolic Primer & Anti-Inflammatory Support by GNC Pro Performance AMP label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Anabolic Primer & Anti-Inflammatory Support by GNC Pro Performance AMP
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Green Filled Capsule(s) Dosage formCapsule Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Palmitic Acid Monoethanolamide
Fenugreek seed extract
Interacts with389 drugs
Fenugreek is a common kitchen spice that is also taken as a supplement, mainly for blood sugar, cholesterol, and to support breast milk production. So...
Fenugreek seed extract monograph & interactionsOther (inactive) ingredients: Gelatin, Cellulose, Stearic Acid, Silica. These complete the product’s ingredient list but are not active constituents.
Anabolic Primer & Anti-Inflammatory Support by GNC Pro Performance AMP Drug Interactions
HelloPharmacist Interaction Report
GNC Pro Performance AMP contains fenugreek seed extract, which has documented interactions with several medication types.
The most serious concern is with blood thinners (anticoagulants) and antiplatelet drugs like warfarin and clopidogrel — fenugreek may add to their effects and increase bleeding risk, which is a Moderate severity interaction.
Read the full breakdown — every affected drug type, severity by severity
Fenugreek also interacts moderately with diabetes medications (it can lower blood sugar further), the heart medication metoprolol (it may lower blood pressure more), the seizure drug phenytoin (it may reduce its levels), the asthma medication theophylline (it may lower its levels), and erectile dysfunction drugs like sildenafil (it may reduce their effect). Altogether, these interactions span 386 individual medications.
We could not check the other active ingredient, Palmitic Acid Monoethanolamide, because we hold no interaction data for it. Before starting this product, run all your current medications through the search tool on this page to make sure nothing you take is affected.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Anabolic Primer & Anti-Inflammatory Support?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Anabolic Primer & Anti-Inflammatory Support interact with 389 drugs. Click any drug to see the details.
1 of the 2 ingredients in Anabolic Primer & Anti-Inflammatory Support interact with drugs. Each result below shows which ingredient is responsible. Fenugreek seed extract
AbciximabReoPro
How Abciximab interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Acetaminophen, Ibuprofen interactionAcetohexamideDymelor
How Acetohexamide interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAspirin, ButalbitalAxotal
How Aspirin, Butalbital interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Aspirin, Butalbital interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with Anabolic Primer & Anti-Inflammatory Support — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Aspirin, Caffeine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Anabolic Primer & Anti-Inflammatory Support with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Fenugreek seed extract
Anticoagulant/Antiplatelet Drugs
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Some of the constituents in fenugreek have antiplatelet effects in animal and in vitro research. However, common fenugreek products might not contain sufficient concentrations of these constituents for clinical effects. A clinical study in patients with coronary artery disease or diabetes shows that taking fenugreek seed powder 2.5 grams twice daily for 3 months does not affect platelet aggregation, fibrinolytic activity, or fibrinogen levels .
Antidiabetes Drugs
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Clinical research shows that fenugreek seed can reduce fasting blood glucose and 2-hour postprandial glucose levels in adults with type 2 diabetes.
Clopidogrel (Plavix)
Theoretically, fenugreek seed might alter the clinical effects of clopidogrel by inhibiting its conversion to the active form.
Animal research shows that fenugreek seed 200 mg/kg daily for 14 days increases the maximum serum concentration of clopidogrel by 21%. It is unclear how this affects the pharmacokinetics of the active metabolite of clopidogrel; however, this study found that concomitant use of fenugreek seed and clopidogrel prolonged bleeding time by an additional 11%.
Metoprolol (Toprol)
Theoretically, fenugreek seed might have additive hypotensive effects when used with metoprolol.
Animal research shows that fenugreek seed 300 mg/kg daily for 2 weeks decreases systolic and diastolic blood pressure by 9% and 11%, respectively, when administered alone, and by 15% and 22%, respectively, when given with metoprolol 10 mg/kg.
Phenytoin (Dilantin)
Theoretically, fenugreek might decrease plasma levels of phenytoin.
Animal research shows that taking fenugreek seeds for 1 week decreases maximum concentrations and the area under the curve of a single dose of phenytoin by 44% and 72%, respectively. This seems to be related to increased clearance. So far, this interaction has not been reported in humans.
Sildenafil (Viagra)
Theoretically, concurrent use of sildenafil and fenugreek might reduce levels and therapeutic effects of sildenafil.
Animal research shows that taking fenugreek seeds for 1 week reduces maximum concentrations and the area under the curve of a single dose of sildenafil by 27% and 48%, respectively. So far, this interaction has not been reported in humans.
Theophylline
Theoretically, fenugreek may reduce the levels and clinical effects of theophylline.
Animal research shows that fenugreek 50 grams daily for 7 days reduces the maximum serum concentration (Cmax) of theophylline by 28% and the area under the plasma drug concentration-time curve (AUC) by 22%.
Warfarin (Coumadin)
Theoretically, fenugreek might have additive effects with warfarin and increase the international normalized ratio (INR).
Some fenugreek constituents have antiplatelet effects, although these might not be present in concentrations that are clinically significant. In one case report, a patient taking warfarin experienced an increased INR when starting to take fenugreek in combination with boldo.
Antihypertensive Drugs
Fenugreek may also have an additive effect on blood pressure-lowering medications. Studies on animals have shown that fenugreek seed can decrease both systolic and diastolic blood pressure by up to 22% when combined with metoprolol. Therefore, it is essential to monitor your blood pressure regularly if you are taking fenugreek and metoprolol together or any other antihypertensive drugs.
Brand information
Manufacturer and brand details for Anabolic Primer & Anti-Inflammatory Support, from the product label.
GNC Pro Performance AMP
See all GNC Pro Performance AMP products- Name
- General Nutrition Corp.
- City
- Pittsburgh
- State
- PA
- ZipCode
- 15222
- Phone Number
- 1-888-462-2548
- Web Address
- www.gnc.com
Anabolic Primer & Anti-Inflammatory Support by GNC Pro Performance AMP: Common Questions
Does Anabolic Primer & Anti-Inflammatory Support by GNC Pro Performance AMP interact with any medications?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Anabolic Primer & Anti-Inflammatory Support is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Anabolic Primer & Anti-Inflammatory Support’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Anabolic Primer & Anti-Inflammatory Support's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 30 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Fenugreek 30 references
- Madar Z, Thorne R. Dietary fiber. Prog Food Nutr Sci 1987;11:153-74.
- Sharma RD, Raghuram TC, Rao NS. Effect of fenugreek seeds on blood glucose and serum lipids in type I diabetes. Eur J Clin Nutr 1990;44:301-6.
- Patil SP, Niphadkar PV, Bapat MM. Allergy to fenugreek (Trigonella foenum graecum). Ann Allergy Asthma Immunol 1997;78:297-300. PubMed
- Lambert J, Cormier J. Potential interaction between warfarin and boldo-fenugreek. Pharmacotherapy 2001;21:509-12. PubMed
- Bordia A, Verma SK, Srivastava KC. Effect of ginger (Zingiber officinale Rosc.) and fenugreek (Trigonella foenumgraecum L.) on blood lipids, blood sugar and platelet aggregation in patients with coronary artery disease. Prostaglandins Leukot Essent Fatty PubMed
- Yalcin SS, Tekinalp G, Ozalp I. Peculiar odor of traditional food and maple syrup urine disease. Pediatr Int 1999;41:108-9. PubMed
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