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Dietary supplement

Anxiety Relief Ingredients & Drug Interactions

by Dr. Garber's

Liquid Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Anxiety Relief is a dietary supplement by Dr. Garber's with 5 active ingredients. Its ingredients are commonly taken for constipation and digestive health, blood sugar support, cough and sore throat.Based on those ingredients, 966 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lime Tree, Fig Tree, Silver Birch. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Anxiety Relief by Dr. Garber's

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (83 mg) without saying how much of each component you get.

Dr. Garber's Anxiety Relief is a liquid containing five active ingredients: Fig Tree, Lime Tree, Silver Birch, Lepidolite, and Hypothalamus extract.

Fig and Lime are plant extracts traditionally used in herbal medicine, Silver Birch contributes plant compounds, and the last two are mineral and animal-derived components. The product also contains glycerin, purified water, and alcohol as inactive ingredients to preserve and carry the active components.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: occasional anxiety brought on by stress.
  • We looked for evidence on: Anxiety disorder, Stress-related anxiety, Generalized anxiety, Panic disorder.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence supporting these ingredients is limited. Fig Tree, Lime Tree, and Silver Birch all carry effectiveness ratings of "Insufficient Reliable Evidence" for the conditions they're traditionally used for — meaning there isn't enough solid clinical data in our records to say whether they work.

We have no effectiveness data on file for Lepidolite or Hypothalamus extract for anxiety or any other condition.

The evidence, ingredient by ingredient Fig Lime Birch

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Fig Tree fruit is generally well tolerated, but concentrated leaf extracts lack solid safety data. Lime is safe in normal food amounts, though concentrated extracts should be avoided without checking with your doctor first.

Silver Birch is generally tolerated in food-like amounts but carries allergy risk and quality concerns. Safety data is not established for Silver Birch during pregnancy or breastfeeding.

Fig Tree shows a "Likely Safe" rating in pregnancy and lactation, but there's insufficient information on Lime Tree for pregnancy and breastfeeding. Rare allergic reactions including anaphylaxis have been reported with fig, and contact dermatitis with both fig leaf and birch.

If you're pregnant, breastfeeding, or have known allergies to plants in the Moraceae or Betulaceae families, talk with your doctor or pharmacist before starting this product.

Side effects, ingredient by ingredient Fig Lime Birch

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Birch, Fig, Lime.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 967 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Dr. Garber's Anxiety Relief, check with your own doctor or pharmacist if you take photosensitizing drugs like quinolone antibiotics (Cipro), tetracyclines, sulfa drugs, or certain antidepressants — Fig and Lime can raise your risk of severe sun sensitivity.

Also flag blood sugar medications and insulin (Fig may lower blood sugar further), heart drugs and erectile dysfunction medications that are CYP3A4 substrates (Lime may make them stronger), and water pills (Silver Birch may reduce their effect).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product combines several plant and mineral ingredients with limited evidence of effectiveness and some documented medication interactions — most notably with blood sugar drugs, photosensitizing medications, and certain heart drugs. If you take insulin, diabetes medications, antibiotics, antidepressants, water pills, or any drugs for heart health or sexual function, check your specific medications with the tool on this page before taking it.

Talk it over with your own doctor or pharmacist, especially if you're pregnant, breastfeeding, or sun-sensitive.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 21, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Anxiety Relief, straight from the product label.

Brand Dr. Garber's
Barcode (UPC) 189806000022
Net contents 2 fl. Oz.; 60 mL
Market status On market
Date entered into DSLD Sep 21, 2018
DSLD ID 181093
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Anxiety Relief by Dr. Garber's, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
60
UPC/BARCODE
189806000022
IngredientAmount% DV
Proprietary Blend83 mg--
Fig Tree0 NP--
Lime Tree0 NP--
Silver Birch0 NP--
Lepidolite0 NP--
Hypothalamus extract0 NP--

Other ingredients: Glycerin, purified Water, Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Do not use if printed cap seal is broken or missing

FDA Disclaimer Statement

Theses statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

GMO Free Gluten Free

GMP Good Manufacturing Products Practice

Formulation

GMO Free Gluten Free

General Statements

Natural solutions for occasional anxiety brought on by stress.

Heal different

Benefit: For the relief of occasional anxiousness and nervous irritability.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: Take 1.0 ml, directly by mouth or in a small amount of water, two or more times a day, as needed. Children should take half the adult amount.

See for yourself

Anxiety Relief by Dr. Garber's label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Anxiety Relief by Dr. Garber's

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

83 mg per serving

Other (inactive) ingredients: Glycerin, Purified Water, Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Anxiety Relief by Dr. Garber's Drug Interactions

Want to check YOUR meds against Anxiety Relief?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
966Drugs
955 Moderate 11 Minor

Ingredients driving the most interactions

Lime Tree 886
Fig Tree 410

Each ingredient & the kinds of drugs it affects

For each ingredient in Anxiety Relief with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Lime Tree2 drug types · 886 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4. This has been demonstrated in rats treated with sildenafil, a CYP3A4 substrate, and high doses of lime juice.

Likelihood Possible Evidence D
Photosensitizing Drugs

Theoretically, concomitant use of lime oil with photosensitizing drugs may increase the risk of phototoxicity.

Likelihood Possible Evidence D

Fig Tree3 drug types · 410 drugs

Antidiabetes Drugs

Theoretically, fig leaf might enhance the blood glucose lowering effects of hypoglycemic drugs.
A small clinical study in patients with type 1 diabetes shows that consuming a tea made from fig leaves modestly reduces postprandial glucose levels and insulin requirements.

Likelihood Probable Evidence B
Insulin

Fig leaf may enhance the blood glucose lowering effects of insulin.
A small clinical study in patients with type 1 diabetes shows that consuming a tea made from fig leaves modestly reduces postprandial glucose levels and insulin requirements.

Likelihood Probable Evidence B
Photosensitizing Drugs

Theoretically, fig might increase the risk of photosensitivity when used in combination with photosensitizing drugs.
Many cases of photodermatitis from fig leaf have been reported. Some drugs that also cause photosensitivity include amitriptyline (Elavil), quinolones (Ciprofloxacin, others), sulfa drugs (Septra, Bactrim, others), and tetracycline.

Likelihood Possible Evidence D

Silver Birch1 drug type · 75 drugs

Diuretic Drugs

Theoretically, birch might interfere with diuretic therapy.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Anxiety Relief, from the product label.

Dr. Garber's

See all Dr. Garber's products
Name
Dr. Garber's LLC
City
Santa Fe
State
NM
ZipCode
87501
Phone Number
877-374-2723
Web Address
www.drgarbers.com
Pharmacist Counseling Corner

Anxiety Relief by Dr. Garber's: Common Questions

Does Anxiety Relief by Dr. Garber's interact with any medications?
Yes. Based on its ingredients, Anxiety Relief has a known interaction with 966 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Anxiety Relief contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is Fig Tree safe to take every day?
Fig fruit as food is well tolerated. However, this product contains a concentrated leaf extract, and safety data for long-term medicinal use of fig leaves isn't established. Talk with your pharmacist about how often and how long you plan to use it.
Can I take this if I'm pregnant?
Fig Tree carries a "Likely Safe" rating in pregnancy, but we don't have pregnancy safety information on file for Lime Tree, Silver Birch, Lepidolite, or Hypothalamus extract. Your doctor or pharmacist can weigh what we know and help you decide whether it's right for you.
Will this cause sun sensitivity?
Fig Tree and Lime Tree can increase your risk of photodermatitis — painful sun burns that in rare cases have been serious enough to require hospitalization. If you use this product, avoid excessive sun exposure and use sunscreen. Stop the product immediately if you develop redness or burning on your skin after sun exposure.
What does each ingredient do?
These ingredients are used in traditional herbal medicine, but the evidence supporting them for anxiety or any other specific condition is insufficient in our data. Fig and Lime are plants; Silver Birch is a tree extract; Lepidolite is a mineral; and Hypothalamus extract comes from animal tissue.
Is alcohol in this product a problem?
This liquid contains alcohol as a preservative. If you avoid alcohol for medical, religious, or personal reasons, check the label for the exact amount and confirm with your pharmacist whether it's right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Anxiety Relief is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Anxiety Relief label
Sources

Sources & How We Checked

Anxiety Relief's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 37 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Fig 13 references
  1. Gandolfo M, Baeza M, De Barrio M, Anaphylaxis after eating figs. Allergy 2001;56:462-3. PubMed
  2. Serraclara A, Hawkins F, Perez C, et al. Hypoglycemic action of an oral fig-leaf decoction in type-I diabetic patients. Diabetes Res Clin Pract 1998;39:19-22. PubMed
  3. Rubnov S, Kashman Y, Rabinowitz R, et al. Suppressors of cancer cell proliferation from fig (Ficus carica) resin: isolation and structure elucidation. J Nat Prod 2001;64:993-6.
  4. Dechamp C, Bessot JC, Pauli G, Deviller P. First report of anaphylactic reaction after fig (Ficus carica) ingestion. Allergy 1995;50:514-6.
  5. Zaynoun ST, Aftimos BG, Abi Ali L, et al. Ficus carica; isolation and quantification of the photoactive components. Contact Dermatitis 1984;11:21-5.
  6. Lembo G, Lo Presti M, Balato N. Phytophotodermatitis due to ficus carica. Photodermatol 1985;2:119-20.
  7. Bollero, D., Stella, M., Rivolin, A., Cassano, P., Risso, D., and Vanzetti, M. Fig leaf tanning lotion and sun-related burns: case reports. Burns 2001;27(7):777-779. PubMed
  8. Ozdamar, E., Ozbek, S., and Akin, S. An unusual cause of burn injury: fig leaf decoction used as a remedy for a dermatitis of unknown etiology. J.Burn Care Rehabil. 2003;24(4):229-233. PubMed
  9. Munteanu, M. Contact dermatitis to the sap of fig-tree. Rev.Med.Chir Soc.Med.Nat.Iasi 1989;93(3):602.
  10. Lembo, G., Lo, Presti M., and Balato, N. Phytophotodermatitis due to ficus carica. Photodermatol. 1985;2(2):119-120.
  11. Micali, G., Nasca, M. R., and Musumeci, M. L. Severe phototoxic reaction secondary to the application of a fig leaves' decoction used as a tanning agent. Contact Dermatitis 1995;33(3):212-213. PubMed
  12. Bonamonte D, Foti C, Lionetti N, Rigano L, Angelini G. Photoallergic contact dermatitis to 8-methoxypsoralen in Ficus carica. Contact Dermatitis. 2010;62(6):343-8.
  13. Pinto AR, Machado Cunha I, Rebelo Gomes E. Fig Tree-Induced Phytophotodermatitis: A Case Report on the Perils of a Hobby. Cureus 2023;15(7):e41888. PubMed

See these in context on the Fig monograph →

Lime 20 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Roesyanto-Mahadi ID, Geursen-Reitsma AM, van Joost T, et al. Sensitization to fragrance materials in Indonesian cosmetics. Contact Dermatitis 1990;22:212-7. PubMed
  3. Naganuma M, Hirose S, Nakayama Y, et al. A study of the phototoxicity of lemon oil. Arch Dermatol Res 1985;278:31-6. . PubMed
  4. Bailey DG, Dresser GK, Bend JR. Bergamottin, lime juice, and red wine as inhibitors of cytochrome P450 3A4 activity: comparison with grapefruit juice. Clin Pharmacol Ther 2003;73:529-37. PubMed
  5. Weber, I. C., Davis, C. P., and Greeson, D. M. Phytophotodermatitis: the other "lime" disease. J Emerg.Med 1999;17(2):235-237. PubMed
  6. Wagner, A. M., Wu, J. J., Hansen, R. C., Nigg, H. N., and Beiere, R. C. Bullous phytophotodermatitis associated with high natural concentrations of furanocoumarins in limes. Am.J Contact Dermat. 2002;13(1):10-14. PubMed
  7. Garcia, O. P., Diaz, M., Rosado, J. L., and Allen, L. H. Ascorbic acid from lime juice does not improve the iron status of iron-deficient women in rural Mexico. Am.J.Clin.Nutr. 2003;78(2):267-273. PubMed
  8. Coffman, K., Boyce, W. T., and Hansen, R. C. Phytophotodermatitis simulating child abuse. Am.J Dis.Child 1985;139(3):239-240. PubMed
  9. Adegoke SA, Oyelami OA, Olatunya OS, Adeyemi LA. Effects of lime juice on malaria parasite clearance. Phytother Res. 2011;25(10):1547-50. PubMed
  10. Adegoke SA, Shehu UA, Mohammed LO, Sanusi Y, Oyelami OA. Influence of lime juice on the severity of sickle cell anemia. J Altern Complement Med. 2013;19(6):588-92. PubMed
  11. Assarian Z, Nixon RL. Protein contact dermatitis caused by lime in a pastry chef. Contact Dermatitis. 2015;73(1):54-6. PubMed
  12. Bamise CT, Dinyain VE, Kolawole KA. Dental erosion due to lime consumption; review of literature and case report. East Afr J Public Health. 2009;6(2):141-3. PubMed
  13. Flugman SL. Mexican beer dermatitis: a unique variant of lime phytophotodermatitis attributable to contemporary beer-drinking practices. Arch Dermatol. 2010;146(10):1194-5. PubMed
  14. Galvañ-Pérez Del Pulgar JI, Linares-Barrios M, Galvañ-Pozo JI Jr. Acropigmentation of the dorsum of the hands from preparing mojitos: A lime-induced phytophotodermatosis. Actas Dermosifiliogr. 2016;107(3):253-5. DOI
  15. Hemmerling A, Potts M, Walsh J, Young-Holt B, Whaley K, Stefanski DA. Lime juice as a candidate microbicide? An open-label safety trial of 10% and 20% lime juice used vaginally. J Womens Health (Larchmt). 2007;16(7):1041-51. PubMed
  16. Mauck CK, Ballagh SA, Creinin MD, et al. Six-day randomized safety trial of intravaginal lime juice. J Acquir Immune Defic Syndr. 2008;49(3):243-50. PubMed
  17. Mioduszewski M, Beecker J. Phytophotodermatitis from making sangria: a phototoxic reaction to lime and lemon juice. CMAJ. 2015;187(10):756. PubMed
  18. Rungruanghiranya S, Ekpanyaskul C, Sakulisariyaporn C, Watcharanat P, Akkalakulawas K. Efficacy of fresh lime for smoking cessation. J Med Assoc Thai. 2012;95 Suppl 12:S76-82.
  19. Swerdlin A, Rainey D, Storrs FJ. Fragrance mix reactions and lime allergic contact dermatitis. Dermatitis. 2010;21(4):214-6. DOI
  20. Ademosun AO, Mohammed A, Oboh G, Ajeigbe OF. Influence of lemon (Citrus limon) and lime (Citrus aurantifolia) juices on the erectogenic properties of sildenafil in rats with L-NAME-induced erectile dysfunction. J Food Biochem 2022;46(2):e14074.

See these in context on the Lime monograph →

Birch 4 references
  1. Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
  2. Lahti, A. and Hannuksela, M. Immediate contact allergy to birch leaves and sap. Contact Dermatitis 1980;6(7):464-465. PubMed
  3. Allam JP, Wuestenberg E, Wolf H, et al. Immunologic response and safety in birch pollen sublingual versus oral vestibule immunotherapy: a pilot study. J Allergy Clin Immunol. 2014;133(6):1757-9.e3. PubMed
  4. Meyer-Hoffert U, Brasch J. Allergic contact dermatitis caused by betulin-containing triterpene extract from the outer bark of birch (Betula alba). Contact Dermatitis. 2013;68(6):382-3.

See these in context on the Birch monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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