Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Appetite Suppressant Ingredients & Drug Interactions

by UNALTERED

Appetite Suppressant label
See full label image
Capsule Category: Fiber And Other Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Appetite Suppressant against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Appetite Suppressant is a dietary supplement by UNALTERED with 2 active ingredients. Its ingredients are commonly taken for weight loss and appetite control, constipation, high cholesterol.Based on those ingredients, 2,056 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Glucomannan, Chromium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Appetite Suppressant by UNALTERED

Ask about any prescription or over-the-counter medication and we check it for interactions with Appetite Suppressant by UNALTERED — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Appetite Suppressant by UNALTERED

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 1, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This capsule contains 2 active ingredients: glucomannan and chromium. Glucomannan is a soluble fiber that absorbs water and expands in your digestive tract; it's used to support bowel health and may help with cholesterol and blood sugar management.

Chromium is a mineral that plays a role in how your body handles blood sugar and may support healthy glucose levels. The capsule also contains inactive ingredients — hypromellose, rice flour, magnesium stearate, and silica — which help hold the product together and protect it.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: appetite suppressant.
  • We looked for evidence on: Binge eating disorder, Obesity, weight management, satiety.
  • The closest evidence on file: Glucomannan is rated "Insufficient Reliable Evidence To Rate" for Obesity (Natural Medicines).
  • Also on file: Chromium is rated "Insufficient Reliable Evidence To Rate" for Obesity, Binge eating disorder.

Glucomannan has possibly effective evidence for constipation, diabetes management, and high cholesterol (hyperlipidemia). For blood pressure, there isn't enough reliable evidence to rate it.

Chromium is likely effective for chromium deficiency and possibly effective for diabetes. For prediabetes and blood sugar tolerance issues, it's rated possibly ineffective.

It's also rated possibly ineffective for schizophrenia and high blood pressure.

The evidence, ingredient by ingredient Glucomannan Chromium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Glucomannan is generally well tolerated when you take it with plenty of water, but it can cause bloating, gas, abdominal pain, nausea, diarrhea, or constipation — especially at doses over 3 grams daily. Rarely, it can cause choking or blockage in your esophagus or gut, particularly if swallowed dry without enough liquid.

There isn't enough safety data to know if it's safe during pregnancy, and little is known about breastfeeding — talk to your doctor before using it in either situation. Chromium is generally well tolerated at typical supplement doses.

Common side effects include gastrointestinal irritation, headaches, insomnia, irritability, and mood changes. Rare serious effects include kidney or liver damage and blood cell problems.

The safety data on high or long-term doses is limited. During pregnancy, small amounts from food or a prenatal vitamin are considered acceptable, but extra supplement doses should be avoided unless your doctor recommends it.

The same caution applies to breastfeeding.

Side effects, ingredient by ingredient Glucomannan Chromium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Glucomannan, Chromium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 2,057 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take antidiabetes drugs or insulin — chromium may increase the risk of low blood sugar. If you take levothyroxine (thyroid hormone), chromium may reduce how much your body absorbs.

Glucomannan may also slow absorption of any oral medication taken with it, so spacing doses apart is important. NSAIDs and aspirin may increase chromium levels in your body.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with constipation, blood sugar management, or cholesterol, but it interacts with several important drug categories — especially diabetes medications and thyroid hormone. If you take any oral medications, antidiabetes drugs, insulin, levothyroxine, NSAIDs, or aspirin, check with your doctor or pharmacist before starting it.

Take it with plenty of water to avoid blockage, and remember that it works best as part of a broader approach to your health.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Appetite Suppressant, straight from the product label.

Brand UNALTERED
Barcode (UPC) X003A0WXZD
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Jun 20, 2024
DSLD ID 302422
Product type Fiber And Other Nutrients
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult Female (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Appetite Suppressant by UNALTERED, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s), 2 Capsule(s)
Maximum serving Sizes:
1 Capsule(s), 2 Capsule(s)
Servings per container
30
UPC/BARCODE
X003A0WXZD
IngredientAmount% DV
Glucomannan1000 mg, 2000 mg--
Chromium500 mg, 1000 mcg1429%, 2858%

Other ingredients: Hypromellose, Rice Flour, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Serving Size 2 Capsules, 4 Capsules Servings 60, 30

New

How to get best results:

Formulation

Total amounts of appetite suppressing ingredients Unaltered appetite suppressant 2000 mg Average appetite suppressant 50 mg

Fully dosed

Vegan friendly

Helps with weight management Suppressing appetite Insulin sensitivity

Seals/Symbols

Manufactured in the USA FDA registered manufacturer

Formula

Appetite Suppressant for Women

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested/Recommended/Usage/Directions

How To Use Initial Use Take one capsule with a full 8 oz glass of water 30 minutes before breakfast, and one capsule with a full 8 oz glass of water 30 minutes before lunch. Continued Use If well-tolerated, increase dosage to two capsules with a full 8 oz glass of water 30 minutes before breakfast, and two capsules with a full 8 oz glass of water 30 minutes before lunch, for a total of 4 capsules daily.

FDA Statement of Identity

Dietary Supplement

Storage

Storage Instructions: Store in a cool, dry place.

Precautions

Notice: For use as a dietary supplement only.

Warning: Take this product with at least a full 8 oz. cup of water. Taking this product without adequate fluid may cause it to swell and block your throat or esophagus and may cause choking. Do not take this product if you have difficulty swallowing. If you experience chest pain, vomiting or difficulty swallowing or breathing after taking this product, seek immediate medical attention.

If pregnant, nursing or taking any medications, consult a healthcare professional before use.

Keep out of reach of children.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Appetite Suppressant by UNALTERED label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Appetite Suppressant label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Appetite Suppressant by UNALTERED

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Glucomannan

Interacts with
2,022 drugs
1000 mg per serving

Glucomannan is a soluble fiber from the konjac root that swells into a gel in your stomach, which may help with mild weight loss, constipation, and mo...

Glucomannan monograph & interactions

Chromium

Interacts with
178 drugs
500 mg per serving Form: Chromium Picolinate, Cocoa

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control i...

Chromium monograph & interactions

Other (inactive) ingredients: Hypromellose, Rice Flour, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Appetite Suppressant by UNALTERED Drug Interactions

Want to check YOUR meds against Appetite Suppressant?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,056Drugs
2,050 Moderate 6 Minor

Ingredients driving the most interactions

Glucomannan 2,022
Chromium 178

Individual Drug Interactions

The ingredients in Appetite Suppressant interact with 2,056 drugs. Click any drug to see the details.

2 of the 2 ingredients in Appetite Suppressant interact with drugs. Each result below shows which ingredient is responsible. Glucomannan Chromium

Each ingredient & the kinds of drugs it affects

For each ingredient in Appetite Suppressant with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Glucomannan1 drug type · 2,022 drugs

Oral Drugs

Theoretically, glucomannan may decrease absorption of drugs taken orally.
Due to its viscosity and bulking effects, there is concern that glucomannan can decrease the absorption of oral drugs. A small clinical study in healthy volunteers shows that taking glyburide 2.5 mg plus glucomannan 3.9 grams with breakfast reduces plasma levels of glyburide when compared with breakfast and glyburide alone. In addition, animal research demonstrates this effect on amoxicillin, but shows increased absorption of metronidazole. This mouse model also demonstrates that metronidazole elimination is prolonged, but amoxicillin elimination is enhanced by 38%; glucomannan may also affect the distribution of some drugs. To avoid changes in absorption, take glucomannan 30-60 minutes after taking oral drugs.

Likelihood Probable Evidence B
Glucomannan full monograph & interactions

Chromium5 drug types · 178 drugs

Antidiabetes Drugs

Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Some research shows that taking chromium might lower blood glucose levels, especially in patients with poorly controlled type 2 diabetes.

Likelihood Possible Evidence A
Insulin

Theoretically, concomitant use of chromium and insulin might increase the risk of hypoglycemia.
In clinical research, chromium has been shown to increase insulin sensitivity,

Likelihood Possible Evidence B
Levothyroxine (Synthroid, Others)

Chromium might bind levothyroxine in the intestinal tract and decrease levothyroxine absorption.
Clinical research in healthy volunteers shows that taking chromium picolinate 1000 mcg with levothyroxine 1 mg decreases serum levels of levothyroxine by 17% when compared to taking levothyroxine alone. Advise patients to take levothyroxine at least 30 minutes before or 3-4 hours after taking chromium.

Likelihood Probable Evidence B
Aspirin

Theoretically, aspirin might increase chromium absorption.
Animal research suggests that aspirin may increase chromium absorption and chromium levels in the blood.

Likelihood Possible Evidence D
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)

NSAIDs might increase chromium levels in the body.
Drugs that are prostaglandin inhibitors, such as NSAIDs, seem to increase chromium absorption and retention.

Likelihood Possible Evidence D
Chromium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Appetite Suppressant, from the product label.

UNALTERED

See all UNALTERED products
Name
Unaltered, LLC
Phone Number
844-862-5837
Web Address
www.UnalteredAthletics.com
Pharmacist Counseling Corner

Appetite Suppressant by UNALTERED: Common Questions

Does Appetite Suppressant by UNALTERED interact with any medications?
Yes. Based on its ingredients, Appetite Suppressant has a known interaction with 2,056 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Appetite Suppressant contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I have diabetes and take diabetes medications?
Not without checking first. Both ingredients may affect blood sugar — glucomannan may help it, but chromium might lower it further and increase your risk of low blood sugar (hypoglycemia). Talk to your doctor or pharmacist before starting, as they may need to monitor your blood sugar or adjust your medication.
Will this interfere with my thyroid medication (levothyroxine)?
Yes, chromium may bind to levothyroxine in your intestines and reduce how much your body absorbs it. A clinical study showed a 17% decrease in thyroid hormone levels. Ask your doctor or pharmacist whether you should take this product, and if so, how to space the doses.
What are the most common side effects?
Glucomannan commonly causes bloating, gas, abdominal pain, constipation, diarrhea, nausea, or vomiting — especially at higher doses or if you don't drink enough water. Chromium may cause gastrointestinal irritation, headaches, insomnia, irritability, or mood changes. Both are usually mild and subside over time when taken properly.
Is it safe to take during pregnancy?
There isn't enough safety data on glucomannan to know either way — talk to your doctor before using it. For chromium, small amounts from food or a prenatal vitamin are considered acceptable, but extra supplement doses should be avoided unless your doctor advises it.
Do I need to take this at a certain time away from my other medications?
Yes. Because glucomannan may slow the absorption of oral drugs, spacing doses is important — ask your doctor or pharmacist for specific timing. If you take levothyroxine, you should also space it from this product to avoid interference with thyroid hormone absorption.
What's glucomannan and why is it in here?
Glucomannan is a soluble fiber that absorbs water and swells in your digestive tract. It supports bowel regularity and may help lower cholesterol and blood sugar. It's included because it works on digestion and may support your body's natural appetite signals, though you must take it with plenty of water to avoid blockage.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Appetite Suppressant is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Appetite Suppressant label
Go deeper

The Full Monographs Behind Appetite Suppressant’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glucomannan

Interacts with 2,022 drugs

Glucomannan is a soluble fiber from the konjac root that swells into a gel in your stomach, which may help with mild weight loss, constipation, and modestly lowering cholesterol. It is gener...

Read the full Glucomannan monograph → Herb & supplement monograph

Chromium

Interacts with 178 drugs

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control in certain people with type 2 diabetes, b...

Read the full Chromium monograph →
Sources

Sources & How We Checked

Appetite Suppressant's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 68 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glucomannan 15 references
  1. Henry DA, Mitchell AS, Aylward J, et al. Glucomannan and risk of oesophageal obstruction. Br Med J 1986;292:591-2. PubMed
  2. Shima K, Tanaka A, Ikegami H, et al. Effect of dietary fiber, glucomannan, on absorption of sulfonylurea in man. Horm Metab Res 1983;15:1-3. PubMed
  3. Villaverde, A. F., Benlloch, S., Berenguer, M., Miguel, Rayon J., Pina, R., and Berenguer, J. Acute hepatitis of cholestatic type possibly associated with the use of glucomannan (amorphophalus konjac). J Hepatol. 2004;41(6):1061-1062. PubMed
  4. Yoshida, M., Vanstone, C. A., Parsons, W. D., Zawistowski, J., and Jones, P. J. Effect of plant sterols and glucomannan on lipids in individuals with and without type II diabetes. Eur.J Clin Nutr. 2006;60(4):529-537. PubMed
  5. Wood, R. J., Fernandez, M. L., Sharman, M. J., Silvestre, R., Greene, C. M., Zern, T. L., Shrestha, S., Judelson, D. A., Gomez, A. L., Kraemer, W. J., and Volek, J. S. Effects of a carbohydrate-restricted diet with and without supplemental soluble fiber
  6. Vanderbeek, P. B., Fasano, C., O'Malley, G., and Hornstein, J. Esophageal obstruction from a hygroscopic pharmacobezoar containing glucomannan. Clin Toxicol.(Phila) 2007;45(1):80-82. PubMed
  7. Bernstein, J. A., Crandall, M. S., and Floyd, R. Respiratory sensitization of a food manufacturing worker to konjac glucomannan. J Asthma 2007;44(8):675-680. PubMed
  8. Shichijo, K., Kobayashi, Y., Fueki, R., Shimoyama, K., and Masaya, M. [2 cases of konjac bronchial asthma found outside the "konnyaku" producing district]. Arerugi 1969;18(2):97-100.
  9. Carabin IG, Lyon MR, Wood S, et al. Supplementation of the diet with the functional fiber PolyGlycoplex is well tolerated by healthy subjects in a clinical trial. Nutr J 2009;8:9. PubMed
  10. Lyon MR, Reichert RG. The effect of a novel viscous polysaccharide along with lifestyle changes on short-term weight loss and associated risk factors in overweight and obese adults: an observational retrospective clinical program analysis. Altern Med Rev
  11. Lyon M, Wood S, Pelletier X, et al. Effects of a 3-month supplementation with a novel soluble highly viscous polysaccharide on anthropometry and blood lipids in nondieting overweight or obese adults. J Hum Nutr Diet 2011;24(4):351-9. PubMed
  12. Han Y, Zhang L, Liu XQ, Zhao ZJ, Lv LX. Effect of glucomannan on functional constipation in children: a systematic review and meta-analysis of randomised controlled trials. Asia Pac J Clin Nutr 2017;26(3):471-7.
  13. Health Canada Safety Alert. Health Canada Advises Canadians that natural health products containing glucomannan may cause serious choking if used with insufficient fluid. January 29, 2010. Alert # RA-110003825. https://healthycanadians.gc.ca/recall-alert-
  14. Mortensen A, Aguilar F, Crebelli, et al. EFSA Panel on Food Additives and Nutrient Sources added to Food. Re-evaluation of konjac gum (E 425 i) and konjac glucomannan (E425 ii) as food additives. EFSA Journal 2017;15(6):4864.
  15. Zhang Y, Aldamarany WAS, Song G, et al. Influence of konjac glucomannan and its derivatives on the oral pharmacokinetics of antimicrobial agent in antibiotics cocktails: Keep vigilant on dietary fiber supplement. Int J Biol Macromol 2023;251:126306. PubMed

See these in context on the Glucomannan monograph →

Chromium 53 references
  1. Cerulli J, Grabe DW, Gauthier I, et al. Chromium picolinate toxicity. Ann Pharmacother 1998;32:428-31. PubMed
  2. Urberg M, Zemel MB. Evidence for synergism between chromium and nicotinic acid in the control of glucose tolerance in elderly humans. Metabolism 1987;36:896-9. PubMed
  3. Mohamedshah FY, Moser-Veillon PB, Yamini S, et al. Distribution of a stable isotope of chromium (53Cr) in serum, urine, and breast milk in lactating women. Am J Clin Nutr 1998;67:1250-5. PubMed
  4. Wasser WG, Feldman NS, D'Agati VD. Chronic renal failure after ingestion of over-the-counter chromium picolinate. [letter]. Ann Intern Med 1997;126:410. PubMed
  5. Mertz W. Interaction of chromium with insulin: a progress report. Nutr Rev 1998;56:174-7. PubMed
  6. Anderson RA. Chromium, glucose intolerance and diabetes. J Am Coll Nutr 1998;17:548-55. PubMed
  7. McLeod MN, Gaynes BN, Golden RN. Chromium potentiation of antidepressant pharmacotherapy for dysthymic disorder in 5 patients. J Clin Psych 1999;60:237-40. PubMed
  8. Fowler JF Jr. Systemic contact dermatitis caused by oral chromium picolinate. Cutis 2000;65:116. DOI
  9. Trent LK, Thieding-Cancel D. Effects of chromium picolinate on body composition. J Sports Med Phys Fitness 1995;35:273-80.
  10. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  11. Rabinovitz H, Friedensohn A, Leibovitz A, et al. Effect of chromium supplementation on blood glucose and lipid levels in type 2 diabetes mellitus elderly patients. Int J Vitam Nutr Res 2004;74:178-82. PubMed
  12. Lanca S, Alves A, Vieira AI, et al. Chromium-induced toxic hepatitis. Eur J Intern Med 2002;13:518-20. PubMed
  13. Kockler DR, McCarthy MW, Lawson CL. Seizure activity and unresponsiveness after hydroxycut ingestion. Pharmacotherapy 2001;21:647-51.. PubMed
  14. Davidson JR, Abraham K, Connor KM, McLeod MN. Effectiveness of chromium in atypical depression: a placebo-controlled trial. Biol Psychiatry 2003;53:261-4.. PubMed
  15. Food Standards Agency. Medicines and Healthcare products Regulatory Agency (MHRA). Expert Group on Vitamins and Minerals. Available at: http://cot.food.gov.uk/sites/default/files/vitmin2003.pdf.
  16. Mouser JF, Hak EB, Helms RA, et al. Chromium and zinc concentrations in pediatric patients receiving long-term parenteral nutrition. Am J Health Syst Pharm 1999;56:1950-6. PubMed
  17. Stevens T, Qadri A, Zein NN. Two patients with acute liver injury associated with use of the herbal weight-loss supplement hydroxycut. Ann Intern Med 2005;142:477-8. PubMed
  18. Wani S, Weskamp C, Marple J, Spry L. Acute tubular necrosis associated with chromium picolinate-containing dietary supplement. Ann Pharmacother 2006;40:563-6. PubMed
  19. Kleefstra N, Houweling ST, Jansman FG, et al. Chromium treatment has no effect in patients with poorly controlled, insulin-treated type 2 diabetes in an obese Western population: a randomized, double-blind, placebo-controlled trial. Diabetes Care 2006;29: PubMed
  20. Martin J, Wang ZQ, Zhang XH, et al. Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes. Diabetes Care 2006;29:1826-32. PubMed
  21. Singer GM, Geohas J. The effect of chromium picolinate and biotin supplementation on glycemic control in poorly controlled patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized trial. Diabetes Technol Ther 2006;8:636-43. PubMed
  22. John-Kalarickal J, Pearlman G, Carlson HE. New medications which decrease levothyroxine absorption. Thyroid 2007;17:763-5. PubMed
  23. Yazaki Y, Faridi Z, Ma Y, et al. A pilot study of chromium picolinate for weight loss. J Altern Complement Med 2010;16:291-9. PubMed
  24. Davis ML, Seaborn CD, and Stoecker BJ. Effects of over-the-counter drugs on chromium retention and urinary excretion in rats. Nutrition Research 1995;15(2):201-210.
  25. Young P, Turiansky G, Bonner M, and et al. Acute generalized exanthematous pustulosis induced by chromium picolinate. J.Am Acad.Dermatol. 1999;41(5 Pt 2):820-823. PubMed
  26. Gibb, H. J., Lees, P. S., Pinsky, P. F., and Rooney, B. C. Lung cancer among workers in chromium chemical production. Am J Ind.Med 2000;38(2):115-126. DOI
  27. Gibb, H. J., Lees, P. S., Pinsky, P. F., and Rooney, B. C. Clinical findings of irritation among chromium chemical production workers. Am J Ind.Med 2000;38(2):127-131. PubMed
  28. Pittler, M. H. and Ernst, E. Dietary supplements for body-weight reduction: a systematic review. Am.J.Clin Nutr. 2004;79(4):529-536. PubMed
  29. Pei, D., Hsieh, C. H., Hung, Y. J., Li, J. C., Lee, C. H., and Kuo, S. W. The influence of chromium chloride-containing milk to glycemic control of patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial. Metabolism 2 PubMed
  30. Hisatomi, K., Ishii, H., Hashiguchi, K., Seki, M., Ide, M., Sugiyama, K., Ishimoto, H., Nakayama, S., Mukae, H., and Kohno, S. Interstitial pneumonia caused by inhalation of fumes of nickel and chrome. Respirology. 2006;11(6):814-817. PubMed
  31. Kleefstra, N., Houweling, S. T., Bakker, S. J., Verhoeven, S., Gans, R. O., Meyboom-de Jong, B., and Bilo, H. J. Chromium treatment has no effect in patients with type 2 diabetes in a Western population: a randomized, double-blind, placebo-controlled tri DOI
  32. Parsons, A., Ingram, J., Inglis, J., Aveyard, P., Johnstone, E., Brown, K., Franklin, M., and Bermudez, I. A proof of concept randomised placebo controlled factorial trial to examine the efficacy of St John's wort for smoking cessation and chromium to pr
  33. Bagdon RE and Hazen RE. Skin permeation and cutaneous hypersensitivity as a basis for making risk assessments of chromium as a soil contaminant. Environ.Health Perspect. 1991;92:111-119. PubMed
  34. Bharmal, S. V., Moyes, V., Ahmed, S., and Grossman, A. Hypoglycaemia: possible mediation by chromium salt medication. Hormones.(Athens.) 2010;9(2):181-183. PubMed
  35. Krol, E., Krejpcio, Z., Byks, H., Bogdanski, P., and Pupek-Musialik, D. Effects of chromium brewer's yeast supplementation on body mass, blood carbohydrates, and lipids and minerals in type 2 diabetic patients. Biol.Trace Elem.Res. 2011;143(2):726-737.
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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