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Dietary supplement

Boost Ingredients & Drug Interactions

by UNALTERED

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Boost is a dietary supplement by UNALTERED with 2 active ingredients. Its ingredients are commonly taken for low libido and sexual function, athletic performance and muscle building, testosterone support.Based on those ingredients, 259 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Tribulus terrestris Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Boost by UNALTERED

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Boost contains 2 active ingredients: tribulus terrestris extract and red maca root extract. Tribulus is traditionally used for sexual function and athletic performance.

Red maca root extract is similarly used for sexual health and general wellness. The capsule also contains several inactive ingredients — hypromellose, silica, and magnesium stearate — which are fillers and binders used to form and hold the capsule together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: boost drive desire enhance lubrication regulate hormones.
  • We looked for evidence on: Sexual desire, Sexual dysfunction, Erectile dysfunction (ED), Antidepressant-induced sexual dysfunction, Premature ejaculation, Male infertility — and 4 related terms.
  • The strongest evidence on file: Tribulus is rated "Possibly Effective" for Sexual dysfunction (Natural Medicines).
  • Also on file: Tribulus is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED), Menopausal symptoms, Premature ejaculation, Male infertility.
  • Also on file: Maca is rated "Insufficient Reliable Evidence To Rate" for Antidepressant-induced sexual dysfunction, Postmenopausal conditions.

Tribulus terrestris for sexual dysfunction is rated possibly effective. For athletic performance, the evidence suggests it is possibly ineffective.

For benign prostatic hyperplasia (enlarged prostate), there is insufficient reliable evidence to rate it. Red maca root extract has insufficient reliable evidence for all conditions tracked in our data — amenorrhea (absence of periods), anemia of chronic disease, antidepressant-induced sexual dysfunction, athletic performance, and osteoporosis.

In short, the data we hold does not establish that it works for any of these uses.

The evidence, ingredient by ingredient Tribulus Maca

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Tribulus terrestris is often well tolerated short-term in healthy adults, though long-term safety data are limited. Rare serious side effects reported include liver and kidney injury, seizures, and painful erection with sexual dysfunction.

More common are stomach complaints like abdominal pain, cramping, nausea, vomiting, diarrhea, or constipation — though one study found these rates similar to placebo. Red maca root extract is generally well tolerated as a food, but long-term supplement safety has not been studied.

Uncooked maca may cause stomach pain. The safety data advises against both ingredients during pregnancy and breastfeeding — neither has enough reliable information to know they are safe in those situations.

Side effects, ingredient by ingredient Tribulus Maca

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Tribulus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 259 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Boost, double-check your medications. The most important ones to flag are blood pressure medications (antihypertensives) — tribulus can lower blood pressure further.

Also check if you take diabetes medication (antidiabetes drugs) or lithium. If you take any of these, your pharmacist may need to adjust your dose or monitor you more closely.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Boost may be worth considering if you're interested in tribulus for sexual function and your medications don't interact with it. However, if you take blood pressure medication, diabetes medication, or lithium, you need to check with your pharmacist first — the interactions are real and potentially serious.

Talk to us before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Boost, straight from the product label.

Brand UNALTERED
Barcode (UPC) X003Q6GF8H
Net contents 90 Vegan Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 302443
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult Female (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Boost by UNALTERED, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
X003Q6GF8H
IngredientAmount% DV
Tribulus terrestris Extract750 mg--
Red Maca Root Extract1500 mg--

Other ingredients: Hypromellose, Silica, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Helps Boost drive & desire Enhance lubrication Ditch the mood swings Regulate hormones Fully dosed FDA Registered Manufacturer

Vegan friendly

Seals/Symbols

Manufactured in the USA

General Statements

New

Why choose Unaltered? It's simple... Right ingredients. Right doses.

How to get best results:

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

Total amounts of libido boosting ingredients Unaltered Boost 2250mg Average libido booster 1196mg

FDA Statement of Identity

Dietary Supplement

Storage

Storage instructions: Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Suggested use: For overall female vitality, take 2 capsules in the morning and 1 capsule in the afternoon with food. Alternatively, if using for sexual activity, take 3 capsules 30 minutes before intercourse. Do not exceed 3 capsules within a 24 hours period. For optimal results, do not skip and days of product use.

Precautions

Notice: For use as a dietary supplement only.

See for yourself

Boost by UNALTERED label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Boost by UNALTERED

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Tribulus terrestris Extract

Interacts with
259 drugs
750 mg per serving Form: Saponins

Tribulus is a plant supplement most often marketed to boost libido, testosterone, and athletic performance, but the human evidence behind these claims...

Tribulus terrestris Extract monograph & interactions

Red Maca Root Extract

No known
interactions
1500 mg per serving

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire an...

Red Maca Root Extract monograph & interactions

Other (inactive) ingredients: Hypromellose, Silica, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Boost by UNALTERED Drug Interactions

Want to check YOUR meds against Boost?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
259Drugs
259 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Boost with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Tribulus terrestris Extract3 drug types · 259 drugs

Antidiabetes Drugs

Taking tribulus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that Tribulus can lower blood glucose levels in adults with type 2 diabetes who are taking antidiabetes medications.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that tribulus can lower blood pressure by inhibiting angiotensin-converting enzyme (ACE). Tribulus has also demonstrated hypotensive effects in pre-hypertensive adults.

Likelihood Possible Evidence D
Lithium

Theoretically, tribulus might increase the levels and clinical effects of lithium.
Tribulus is thought to have diuretic properties. Due to these potential diuretic effects, tribulus might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Boost, from the product label.

UNALTERED

See all UNALTERED products
Name
Unaltered, LLC
Phone Number
844-862-5837
Web Address
www.UnalteredAthletics.com
Pharmacist Counseling Corner

Boost by UNALTERED: Common Questions

Does Boost by UNALTERED interact with any medications?
Yes. Based on its ingredients, Boost has a known interaction with 259 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Boost contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm trying to get pregnant or am breastfeeding?
The safety data advises against both tribulus and red maca during pregnancy and breastfeeding. There isn't enough reliable information to know they're safe in those situations. Please talk with your doctor or pharmacist about what's right for you.
What's the difference between tribulus and red maca in this product?
Both are plant extracts traditionally used for sexual health. Tribulus has some research suggesting it may help with sexual dysfunction, though the evidence is modest. Red maca hasn't been studied enough to establish what it does — we just don't have the data yet.
Does this help with athletic performance?
Tribulus is often marketed for athletics, but the evidence suggests it's probably not effective for that purpose. Red maca doesn't have enough data to say either way.
What side effects might I experience?
Most people tolerate it well. The most common complaints are stomach-related — pain, cramping, nausea, vomiting, diarrhea, or constipation — though one study found these similar to placebo. Rare serious effects like liver or kidney injury and seizures have been reported, though they're uncommon.
How long have people been taking this safely?
Tribulus is often well tolerated short-term, but long-term safety data are limited. Red maca is generally well tolerated as a food, but supplement safety hasn't been studied long-term. We don't have robust data on years of use.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Boost label
Sources

Sources & How We Checked

Boost's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tribulus 10 references
  1. Sharifi AM, Darabi R, Akbarloo N. Study of antihypertensive mechanism of Tribulus terrestris in 2K1C hypertensive rats: role of tissue ACE activity. Life Sci 2003;73:2963-71. PubMed
  2. Walker D, Bird A, Flora T, O'Sullivan B. Some effects of feeding Tribulus terrestris, Ipomoea lonchophylla and the seed of Abelmoschus ficulneus on fetal development and the outcome of pregnancy in sheep. Reprod Fertil Dev 1992;4:135-44. PubMed
  3. Al-Ali M, Wahbi S, Twaij H, Al-Badr A. Tribulus terrestris: preliminary study of its diuretic and contractile effects and comparison with Zea mays. J Ethnopharmacol 2003;85:257-60. PubMed
  4. Tabakova, P., Dimitrov, M., Ognyanov, K., and et al. Clinical study of Tribestan in females with endocrine sterility. Documentation for Registration (unpublished) 1999.
  5. Akhtari E, Raisi F, Keshavarz M, et al. Tribulus terrestris for treatment of sexual dysfunction in women: randomized double-blind placebo-controlled study. Daru 2014;22:40. PubMed
  6. Ryan M, Lazar I, Nadasdy GM, et al. Acute kidney injury and hyperbilirubinemia in a young male after ingestion of Tribulus terrestris. Clin Nephrol 2015;83(3):177-83. PubMed
  7. Postigo S, Lima SM, Yamada SS, et al. Assessment of the effects of Tribulus terrestris on sexual function of menopausal women. Rev Bras Ginecol Obstet 2016;38(3):140-6. PubMed
  8. Talasaz AH, Abbasi MR, Abkhiz S, Dashti-Khavidaki S. Tribulus terrestris-induced severe nephrotoxicity in a young healthy male. Nephrol Dial Tranplant 2010;25(11):3792-3. PubMed
  9. Samani NB, Jokar A, Soveid M, Heydari M, Mosavat SH. Efficacy of the hydroalcoholic extract of Tribulus terrestris on the serum glucose and lipid profile of women with diabetes mellitus: a double-blind randomized placebo-controlled clinical trial. J Evid
  10. Siddiqui MA, Itrat M, Mobeen A, Khan MI. Efficacy of khar-i-khasak (Tribulus terrestris Linn.) in prehypertension: a randomized, double-blind, placebo-controlled trial. J Complement Integr Med. 2021.

See these in context on the Tribulus monograph →

Maca 1 reference
  1. Valerio, L. G., Jr. and Gonzales, G. F. Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis. Toxicol.Rev 2005;24(1):11-35. PubMed

See these in context on the Maca monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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