Arjunahills Ingredients & Drug Interactions
by Herbal Hills
What is this page for?
First and foremost: checking Arjunahills against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Arjunahills is a dietary supplement by Herbal Hills with 1 active ingredient. Its ingredients are commonly taken for heart health and circulation, digestive problems (constipation, diarrhea), cholesterol support.Based on those ingredients, 933 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Arjuna bark extract & Arjuna bark powder Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Arjunahills by Herbal Hills
Ask about any prescription or over-the-counter medication and we check it for interactions with Arjunahills by Herbal Hills — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Arjunahills by Herbal Hills
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Arjunahills contains one active ingredient: Arjuna bark extract and Arjuna bark powder blend. The inactive ingredients are magnesium stearate, silica, and a gelatin capsule.
Does it work?
Not established
The evidence for Arjuna bark in heart health is not yet established. Our data rates its use for obesity, high cholesterol (hyperlipidemia), high blood pressure (hypertension), and angina as having insufficient reliable evidence — meaning there isn't enough well-designed research to show whether it works for these conditions.
How safe is it?
Some data gaps
Arjuna bark is generally well tolerated in short-term studies, though long-term safety data and product quality vary widely. There isn't enough safety information to use this supplement during pregnancy or while breastfeeding — the safety data advises against it during both periods.
Meds to double-check
Moderate interaction found
Before you start Arjunahills, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs, any medication broken down by liver enzymes (CYP2D6, CYP2C9, or CYP3A4 substrates), diabetes medications, the muscle relaxer chlorzoxazone, or the heartburn drug omeprazole. All carry Moderate interaction risk with Arjuna bark.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.
Arjunahills may be worth considering if you're interested in traditional heart support, but the evidence for its effectiveness isn't established yet. Because it interacts with a very large number of medications through multiple pathways, you'll want to check your exact prescriptions with your doctor or pharmacist before starting — especially if you take blood thinners, diabetes drugs, or any medication broken down by your liver.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2012.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Arjunahills, straight from the product label.
| Brand | Herbal Hills |
|---|---|
| Barcode (UPC) | 8906008260892 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Nov 21, 2012 |
| DSLD ID | 15527 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Arjunahills by Herbal Hills, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Arjuna bark extract & Arjuna bark powder Blend | 500 mg | -- |
Other ingredients: Magnesium Stearate, Silica, Gelatin Capsule
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
MULTIEFFECTIVE HERB
Cardiac Support
Pure – Natural – Effective Arjuna is the best herb that helps in maintaining healthy heart, relieving mental stresses & nervousness. Arjuna helps maintain cardio vascular function & healthy circulatory system. Current scientific researches have proved that Arjuna acts as a cardio-protective agent. Helps maintaining healthy cholesterol levels.
Contents based on standard Raw Material as per Ayurvedic Text
Batch No. : Exp. Date: Neutral Code # MH/PD/AYU/002/10
Precautions
Keep out of reach of children.
Do not use if inner seal is broken or missing.
Caution : Pregnant or lactating women are advised to consume herbal products under the advice of the Healthcare Practitioner.
Formula
12% Tannins, 0.5% Arjunic Acid
FDA Statement of Identity
Dietary Supplement
HERBAL SUPPLEMENT
Storage
Store in a cool dry place away from direct sunlight.
Seals/Symbols
GMP Good Manufacturing Practice
ISO 22000:2005 CERTIFIED COMPANY
EXTRACT STANDARDIZED EXTRACT
HERBALHILLS
Suggested/Recommended/Usage/Directions
Direction for use : As a dietary supplement take 1 capsule twice daily, preferably after meals or as recommended by a Healthcare Practitioner. For better results it should be taken with warm water
FDA Disclaimer Statement
These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Arjunahills by Herbal Hills label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Arjunahills by Herbal Hills
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Arjuna bark extract & Arjuna bark powder Blend
Interacts with933 drugs
Terminalia is a group of traditional Ayurvedic tree species (most notably Terminalia arjuna) used for heart, digestive, and general wellness purposes....
Arjuna bark extract & Arjuna bark powder Blend monograph & interactionsOther (inactive) ingredients: Magnesium Stearate, Silica, Gelatin Capsule. These complete the product’s ingredient list but are not active constituents.
Arjunahills by Herbal Hills Drug Interactions
HelloPharmacist Interaction Report
Arjunahills by Herbal Hills contains Arjuna bark extract, which interacts with a significant number of medications.
The most serious concern is with blood thinners and antiplatelet drugs (medications that prevent blood clots) — the herb may increase bleeding risk by boosting the blood-thinning effects of drugs like warfarin and aspirin.
Read the full breakdown — every affected drug type, severity by severity
Arjuna bark also inhibits three major liver enzymes (CYP2D6, CYP2C9, and CYP3A4) that break down many prescription medications. This means it can raise the blood levels and side effects of drugs metabolized by these pathways — including certain antidepressants, beta-blockers, statins, and others.
The risk is rated Moderate for each enzyme group.
Two specific medications warrant extra caution: chlorzoxazone (a muscle relaxer) and omeprazole (a heartburn drug). Animal research suggests Arjuna may increase their blood levels and side effects.
Additionally, if you take diabetes medications, Arjuna may theoretically enhance their blood-sugar-lowering effects, raising the risk of low blood sugar (hypoglycemia).
Altogether, these interactions span 934 individual medications. Because your own drugs may fall into one or more of these categories, use the medication checker on this page to see if any of your prescriptions are affected before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Arjunahills?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Arjunahills interact with 933 drugs. Click any drug to see the details.
1 of the 1 ingredient in Arjunahills interact with drugs. Each result below shows which ingredient is responsible. Arjuna bark extract & Arjuna bark powder Blend
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendAnticoagulant/antiplatelet Drugs, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Arjunahills with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Arjuna bark extract & Arjuna bark powder Blend
Anticoagulant/Antiplatelet Drugs
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
In vitro, Terminalia arjuna bark extract inhibits platelet aggregation, decreases platelet activation, and shows antithrombotic properties.
Antidiabetes Drugs
Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Animal and in vitro research shows that Terminalia bellirica and Terminalia chebula fruit and seed extract have hypoglycemic effects.
Chlorzoxazone (Parafon Forte, Paraflex)
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from chlorzoxazone.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of chlorzoxazone increases blood levels of chlorzoxazone and decreases chlorzoxazone clearance. It is speculated that Terminalia chebula reduces the metabolism of chlorzoxazone by inhibiting cytochrome P450 2E1.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2C9 enzymes and reduces CYP2C9 substrate metabolism.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2D6 enzymes and reduces CYP2D6 substrate metabolism.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP3A4 enzymes and reduces CYP3A4 substrate metabolism.
Omeprazole (Prilosec)
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from omeprazole.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of omeprazole increases blood levels of omeprazole and decreases omeprazole clearance. It is speculated that Terminalia chebula reduces the metabolism of omeprazole by inhibiting cytochrome P450 2C19.
Brand information
Manufacturer and brand details for Arjunahills, from the product label.
Herbal Hills
See all Herbal Hills products- Name
- Isha Agro Developers Pvt. Ltd. (An ISO 22000:2005 Certified Company)
- Street Address
- 55-A/B, Lonavala Indl. Co-op. Est. Ltd.
- City
- Nangargaon
- State
- Lonavala
- Phone Number
- 0091 22 2868 6868
- Web Address
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Arjunahills by Herbal Hills: Common Questions
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The Full Monographs Behind Arjunahills’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Arjunahills's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 9 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Terminalia 9 references
- Sabu, M. C. and Kuttan, R. Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol. 2002;81(2):155-160. PubMed
- Rao, N. K. and Nammi, S. Antidiabetic and renoprotective effects of the chloroform extract of Terminalia chebula Retz. seeds in streptozotocin-induced diabetic rats. BMC.Complement Altern.Med 2006;6:17. PubMed
- Murali, Y. K., Anand, P., Tandon, V., Singh, R., Chandra, R., and Murthy, P. S. Long-term effects of Terminalia chebula Retz. on hyperglycemia and associated hyperlipidemia, tissue glycogen content and in vitro release of insulin in streptozotocin induced
- Senthilkumar, G. P. and Subramanian, S. Evaluation of antioxidant potential of Terminalia chebula fruits studies in streptozotocin-induced diabetic rats. Pharmaceutical Biology (Netherlands) 2007;45:511-518.
- Malik N, Dhawan V, Bahl A, Kaul D. Inihbitory effects of Terminalia arjuna on platelet activation in vitro in healthy subjects and patients with coronary artery disease. Platelets. 2009;20(3):183-1190.
- Varghese A, Savai J, Pandita N, Gaud RS. In vitro modulatory effects of Terminalia arjuna, arjunic acid, arjunetin, and arjungenin on CYP3A4, CYP2D6, and CYP2C9 enzyme activity in human liver microsomes. Toxicology Reports. 2015(2):806-16. PubMed
- Wu G, Dong Z, Dong J, et al. Effects of mongolian medicine Terminalia chebula Retz. on 6 CYP450 enzymes in rats. Int J Clin Exp Pathol 2020;13(12):3128-3138.
- Das A, Naveen J, Sreerama YN, Gnanesh Kumar BS, Baskaran V. Low-glycemic foods with wheat, barley and herbs (Terminalia chebula, Terminalia bellerica and Emblica officinalis) inhibit a-amylase, a-glucosidase and DPP-IV activity in high fat and low dose st
- Eltimamy M, Elshamarka M, Aboelsaad M, Sayed M, Moawad H. Effects of alcoholic extract of Terminalia Chebula dried fruit on blood biochemical profile in diabetic rats. J Diabetes Metab Disord 2022;21(1):159-170. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC