Astragalus Root Ingredients & Drug Interactions
by Nature's Way
What is this page for?
First and foremost: checking Astragalus Root against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Astragalus Root is a dietary supplement by Nature's Way with 2 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,125 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Astragalus. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Astragalus Root by Nature's Way
Ask about any prescription or over-the-counter medication and we check it for interactions with Astragalus Root by Nature's Way — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Astragalus Root by Nature's Way
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: astragalus root. It's a plant used in traditional Chinese medicine.
The capsule itself is made from plant-derived material, and the capsule contains cellulose as an inactive ingredient.
Does it work?
Strong evidence
The evidence we hold on astragalus rates as insufficient to judge whether it works. Our data covers uses including hay fever, amenorrhea (absence of menstrual periods), aplastic anemia, angina, asthma, and beta-thalassemia — but for all of them, we don't have enough reliable evidence to say whether it helps or doesn't.
How safe is it?
Well-documented data
Astragalus is generally well tolerated in the short term for healthy adults, though good safety data in humans is limited. Some people have reported dizziness or, in one case, angina-like chest pain after taking it orally, though those effects may not have been caused by the supplement itself.
If you're pregnant or breastfeeding, safety data isn't strong enough — talk with your doctor before using it.
Meds to double-check
Moderate interaction found
Before starting astragalus, check your medications against immunosuppressants, lithium, cyclophosphamide, and antidiabetes drugs — all have documented moderate interactions with this ingredient. Your pharmacist can search your exact medicines on this page.
The bottom line
Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Astragalus might be worth considering if you're interested in traditional immune support and don't take immunosuppressants, lithium, chemotherapy, or diabetes medications. If you do take any of those, check with your pharmacist first.
Because safety data is limited, pregnant and breastfeeding people should skip it.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 23, 2015.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Astragalus Root, straight from the product label.
| Brand | Nature's Way |
|---|---|
| Barcode (UPC) | 033674151808 |
| Net contents | 100 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Dec 23, 2015 |
| DSLD ID | 54461 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Astragalus Root by Nature's Way, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 5 {Calories} | -- |
| Total Carbohydrates | 1 Gram(s) | 1% |
| Dietary Fiber | 1 Gram(s) | 3% |
| Astragalus | 1.41 Gram(s) | -- |
Other ingredients: plant-derived Capsule, Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement
This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General Statements
Premium Herbal
NON GMO
470 mg
Astragalus (Astragalus membranaceus) has been traditionally used to help support immune health.* Our Astragalus is carefully tested and produced to superior quality standards.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Recommendation: Take 3 capsules twice daily.
Precautions
If pregnant, nursing or taking any medications, consult a healthcare professional before use.
Keep out of reach of children.
Safety sealed with printed outer shrinkwrap and inner seal. Do not use if either is broken or missing.
Brand IP Statement(s)
2015
Health through the power of nature, that’s what it means to Trust the Leaf.
Formulation
Gluten free. No sugar, salt, yeast, wheat, corn, soy, dairy products, artificial colors, flavors or preservatives.
Seals/Symbols
VEGETARIAN
General
LN15180.A02 BLK8114A
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Astragalus Root by Nature's Way label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Astragalus Root by Nature's Way
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size3 Capsule(s) Dosage formCapsule Servings per container33 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Dietary Fiber
Interacts with2,025 drugs
Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...
Dietary Fiber monograph & interactionsAstragalus
Interacts with208 drugs
Astragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While...
Astragalus monograph & interactionsOther (inactive) ingredients: Plant-derived Capsule, Cellulose. These complete the product’s ingredient list but are not active constituents.
Astragalus Root by Nature's Way Drug Interactions
HelloPharmacist Interaction Report
Astragalus Root by Nature's Way has documented moderate interactions with several medication types.
The most serious concern is with immunosuppressants — astragalus seems to stimulate your immune system, which could theoretically work against these medications and reduce their effect. If you take drugs to suppress your immune function (such as after a transplant), this matters.
Read the full breakdown — every affected drug type, severity by severity
You'll also want to check if you take lithium for mood disorders. Animal research suggests astragalus has mild water-shedding properties that might reduce how much lithium your body clears, potentially raising its levels and side effects.
The same moderate-level concern applies to cyclophosphamide, a chemotherapy drug — evidence is mixed, but astragalus might interfere with how it works. Additionally, astragalus may lower blood sugar.
If you take diabetes medications, combining them could raise the risk of low blood sugar (hypoglycemia).
Altogether, these interactions span 203 individual medications. Use the medication checker on this page to look up your exact prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Astragalus Root?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Astragalus Root interact with 2,125 drugs. Click any drug to see the details.
2 of the 2 ingredients in Astragalus Root interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Astragalus
GuselkumabTremfya
How Guselkumab interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus + Guselkumab interactionHyaluronidase, RituximabRituxan Hycela
How Hyaluronidase, Rituximab interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus + Hyaluronidase, Rituximab interactionHydrocortisoneAlkindi Sprinkle, Alphaderm, Calmurid HC, Carmol HC cream, Cortef, Dioderm +8 more
How Hydrocortisone interacts with Astragalus Root — through 2 ingredients. Tap an ingredient for the detail:
AstragalusImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus + Hydrocortisone interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Hydrocortisone interactionInebilizumab-cdonUplizna
How Inebilizumab-cdon interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus + Inebilizumab-cdon interactionInfliximab-abdaRenflexis
How Infliximab-abda interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus + Infliximab-abda interactionInfliximab-dyybInflectra
How Infliximab-dyyb interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus + Infliximab-dyyb interactionInfliximab-qbtxIxifi
How Infliximab-qbtx interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus + Infliximab-qbtx interactionInfliximab-axxqAvsola
How Infliximab-axxq interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus + Infliximab-axxq interactionInhaled InsulinExubera
How Inhaled Insulin interacts with Astragalus Root — through 2 ingredients. Tap an ingredient for the detail:
AstragalusAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus + Inhaled Insulin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Inhaled Insulin interactionInsulinNovoRapid Insulin
How Insulin interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus + Insulin interactionInsulin (bovine)Hypurin Bovine Neutral
How Insulin (bovine) interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus + Insulin (bovine) interactionInsulin (human)Afrezza, Novolin 70/30, Novolin L, Novolin N, Novolin R
How Insulin (human) interacts with Astragalus Root — through 2 ingredients. Tap an ingredient for the detail:
AstragalusAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus + Insulin (human) interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Insulin (human) interactionInsulin (pork)Hypurin Porcine Neutral, Lente Iletin II, NPH Iletin, NPH Iletin II, Pork Actrapid, Regular Iletin +1 more
How Insulin (pork) interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus + Insulin (pork) interactionInsulin (rdna)Actrapid, Humalog, Humalog Mix 75/25, Humulin 50/50, Humulin 70/30, Humulin L +8 more
How Insulin (rdna) interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus + Insulin (rdna) interactionInsulin AspartFiasp
How Insulin Aspart interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus + Insulin Aspart interactionInsulin Aspart, Insulin DegludecRyzodeg 70/30
How Insulin Aspart, Insulin Degludec interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus + Insulin Aspart, Insulin Degludec interactionInsulin DegludecTresiba
How Insulin Degludec interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus + Insulin Degludec interactionInsulin Degludec, LiraglutideXultophy 100/3.6
How Insulin Degludec, Liraglutide interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus + Insulin Degludec, Liraglutide interactionInsulin GlargineBasaglar, Lusduna, Semglee
How Insulin Glargine interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus + Insulin Glargine interactionInsulin Glargine (rdna)Lantus
How Insulin Glargine (rdna) interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus + Insulin Glargine (rdna) interactionInsulin Glargine RecombinantToujeo Solostar
How Insulin Glargine Recombinant interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus + Insulin Glargine Recombinant interactionInsulin Glargine, LixisenatideSoliqua 100/33
How Insulin Glargine, Lixisenatide interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus + Insulin Glargine, Lixisenatide interactionInsulin Glulisine (rdna)Apidra
How Insulin Glulisine (rdna) interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus + Insulin Glulisine (rdna) interactionInsulin Human, Sodium ChlorideMyxredlin
How Insulin Human, Sodium Chloride interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus + Insulin Human, Sodium Chloride interactionInsulin LisproAdmelog, Admelog Solostar
How Insulin Lispro interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus + Insulin Lispro interactionInsulin Lispro RecombinantHumalog Kwikpen
How Insulin Lispro Recombinant interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus + Insulin Lispro Recombinant interactionInsulin Lispro-aabcLyumjev
How Insulin Lispro-aabc interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus + Insulin Lispro-aabc interactionInsulin DetermirLevemir
How Insulin Determir interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus + Insulin Determir interactionIxekizumabTaltz
How Ixekizumab interacts with Astragalus Root — through 1 ingredient. Tap an ingredient for the detail:
AstragalusImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus + Ixekizumab interactionLenalidomideRevlimid
How Lenalidomide interacts with Astragalus Root — through 2 ingredients. Tap an ingredient for the detail:
AstragalusImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus + Lenalidomide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Lenalidomide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Astragalus Root with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Dietary Fiber
Carbamazepine (Tegretol)
Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.
Lithium
Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.
Metformin (Glucophage)
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.
Olanzapine (Zyprexa)
Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.
Digoxin (Lanoxin)
Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.
Ethinyl Estradiol
Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.
Oral Drugs
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.
Astragalus
Antidiabetes Drugs
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.
Cyclophosphamide
Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.
Immunosuppressants
Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.
Lithium
Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.
Brand information
Manufacturer and brand details for Astragalus Root, from the product label.
Astragalus Root by Nature's Way: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Astragalus Root is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Astragalus Root’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Black Psyllium
Interacts with 2,025 drugsBlack psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...
Read the full Black Psyllium monograph → Herb & supplement monographAstragalus
Interacts with 208 drugsAstragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While early studies are interesting, strong h...
Read the full Astragalus monograph →Sources & How We Checked
Astragalus Root's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 31 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Black Psyllium 18 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
- Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
- Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
- Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
- Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
- Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
- Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
- Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
- Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
- Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
- Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
- Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
- Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
- Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
- Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
- Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed
Astragalus 13 references
- Upton R, ed. Astragalus Root: Analytical, quality control, and therapeutic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia. 1999:1-25.
- Khoo KS, Ang PT. Extract of astragalus membranaceus and ligustrum lucidum does not prevent cyclophosphamide-induced myelosuppression. Singapore Med J 1995;36:387-90.
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