BCAA Hyperblend Ingredients & Drug Interactions
What is this page for?
First and foremost: checking BCAA Hyperblend against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
BCAA Hyperblend is a dietary supplement by Top Secret Nutrition with 3 active ingredients. Its ingredients are commonly taken for morning sickness in pregnancy, premenstrual syndrome (pms), preventing or treating b6 deficiency.Based on those ingredients, 210 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin B6. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against BCAA Hyperblend by Top Secret Nutrition
Ask about any prescription or over-the-counter medication and we check it for interactions with BCAA Hyperblend by Top Secret Nutrition — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of BCAA Hyperblend by Top Secret Nutrition
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
BCAA Hyperblend has 3 active ingredients. Vitamin B6 is an essential nutrient your body uses for nerve function, immune health, and metabolism—this product includes it at a dose that could potentially reach higher levels than typical food and supplement amounts.
L-leucine is an amino acid (a building block of protein), and there's also a proprietary blend listed as an anabolic and rapid absorption formula, though the exact contents and amounts aren't specified on the label. The product also contains inactive ingredients: gelatin (the capsule), microcrystalline cellulose, magnesium stearate, and silicon dioxide—these are fillers and binders that hold the capsule together.
Does it work?
Couldn't assess
We hold effectiveness data for vitamin B6 only. It's rated effective for treating sideroblastic anemia and vitamin B6 deficiency, and likely effective for lowering homocysteine levels (a blood marker).
It's possibly effective for pregnancy-related nausea and vomiting. There's no effectiveness data on file for L-leucine or the proprietary blend in this product.
How safe is it?
Well-documented data
Vitamin B6 is generally well tolerated at doses under 100 mg daily. The most common side effects from higher doses include headache, nausea, heartburn, and loss of appetite.
At very high doses (especially over 1,000 mg daily or with very high cumulative intake), it can damage nerves in your hands and feet, causing numbness or tingling sensations that may be slow to reverse. The safety notes caution against high doses over time, though normal dietary amounts and standard supplement doses are considered safe.
For pregnancy, vitamin B6 is rated likely safe, though one rating also indicates possibly unsafe—this mixed picture means you should talk with your doctor or pharmacist before taking it if you're pregnant or planning to become pregnant. It's rated likely safe during breastfeeding.
Meds to double-check
Moderate interaction found
Check your medications if you take antihypertensive drugs (blood pressure medicines), amiodarone for heart rhythm, phenobarbital or phenytoin for seizures, or levodopa for Parkinson's disease—all have documented interactions with vitamin B6 in this product.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
BCAA Hyperblend is worth considering if you're an athlete looking for amino acid support and don't take blood pressure medications, seizure medications, or levodopa. If you take any prescription drugs—especially for blood pressure, heart rhythm, or Parkinson's disease—check with us first using the tool on this page.
Pregnant people should discuss this with their doctor or pharmacist before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about BCAA Hyperblend, straight from the product label.
| Brand | Top Secret Nutrition |
|---|---|
| Barcode (UPC) | 858311002776 |
| Net contents | 120 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Feb 25, 2013 |
| DSLD ID | 17560 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for BCAA Hyperblend by Top Secret Nutrition, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Vitamin B6 | 5 mg | 250% |
| L-Leucine | 1800 mg | -- |
| PROPRIETARY ANABOLIC & RAPID ABSORPTION BLEND | 1253 mg | -- |
Other ingredients: Gelatin, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Branched-Chain Amino Acids Of the 20 amino acids that help build protein, nine of these cannot be synthesized in the human body. These nine compounds are referred to as essential amino acids because they must be consumed through food or supplements. Three of these essential amino acids - leucine, isoleucine, and valine - are branched-chain amino acids, or BCAAs. Unlike the other amino acids, BCAA’s are metabolized in muscle rather than in the liver, which means that they play a critical role in muscle development because they reach muscle tissue faster.
THIS IS THE FUTURE...
The BCAA Hyperblend team: BCAA Blend - 3:1:1 ratio of leucine (clinically studied 1.8 grams) to isoleucine and valine. Anabolic Power Blend - We have included Ursolic Acid and Brassinolide to enhance the anabolic and muscle protein synthesis stimulating effect of BCAAs. Absorption and Effectiveness Blend - Astravar (TM) and BioPerine(R) help enhance the absorption of the other powerful ingredients. BCAA hyperblend for: • Enhanced muscle protein synthesis • Improved muscle recovery • Reduced muscle soreness • Increased fat oxidation
ANABOLIC BRANCHED CHAIN FORMULA Enhanced Muscle Protein Synthesis Reduced Muscle Soreness Improved Muscle Recovery Increased Fat Oxidation
YOU WORK HARD - TAKE THE BEST
Top Secret Nutrition’s BCAA Hyperblend combines the power of branched-chain amino acids with ingredients designed to promote anabolic activity and enhance absorption to create an incredible one of a kind BCAA supplement.
Storage
Store in a cool, dry place.
Precautions
Consult your physician prior to use if you have any medical condition.
WARNING: KEEP OUT OF REACH OF CHILDREN.
Use this product as a dietary supplement only.
Do not use if you are pregnant or nursing or if you have any medical condition.
Do not use if seal or package is broken.
Brand IP Statement(s)
BioPerine(R) is a trademark of Sabinsa Corporation. AstraGin(TM) is a Trademark of NuLiv Science.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
MADE IN USA WITH WORLD-WIDE INGREDIENTS (image)
General
20120725 v1.0
FDA Statement of Identity
DIETARY SUPPLEMENT
Suggested/Recommended/Usage/Directions
DIRECTIONS: For best results take 4 capsules anytime you want to enhance protein synthesis.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
BCAA Hyperblend by Top Secret Nutrition label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in BCAA Hyperblend by Top Secret Nutrition
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size4 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Vitamin B6
Interacts with210 drugs
Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...
Vitamin B6 monograph & interactionsL-Leucine
PROPRIETARY ANABOLIC & RAPID ABSORPTION BLEND
Other (inactive) ingredients: Gelatin, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
BCAA Hyperblend by Top Secret Nutrition Drug Interactions
HelloPharmacist Interaction Report
BCAA Hyperblend by Top Secret Nutrition contains vitamin B6, which has documented interactions with several medication types.
The most serious concern is with blood pressure-lowering drugs (antihypertensives); vitamin B6 may add to their effect, potentially lowering your blood pressure more than intended.
Read the full breakdown — every affected drug type, severity by severity
Vitamin B6 can also interact with the heart rhythm medication amiodarone, possibly making your skin more sensitive to sunburn. It may reduce how well two seizure medications—phenobarbital and phenytoin—work in your body by speeding up how your liver clears them.
Additionally, if you take levodopa (Sinemet) alone for Parkinson's disease without carbidopa, vitamin B6 might reduce its effectiveness, though this doesn't happen when carbidopa is part of the combination.
Two other ingredients in this product—L-leucine and a proprietary blend—couldn't be checked against our data. Altogether, these interactions span 208 individual medications.
Use the search tool on this page to check your exact prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against BCAA Hyperblend?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in BCAA Hyperblend interact with 210 drugs. Click any drug to see the details.
1 of the 3 ingredients in BCAA Hyperblend interact with drugs. Each result below shows which ingredient is responsible. Vitamin B6
Benserazide, LevodopaMadopar, Prolopa
How Benserazide, Levodopa interacts with BCAA Hyperblend — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Levodopa Minor
Interaction Summary
Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Read the full Vitamin B6 + Benserazide, Levodopa interactionCarbidopa, LevodopaDhivy, Rytary, Sinemet, Sinemet CR
How Carbidopa, Levodopa interacts with BCAA Hyperblend — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Levodopa Minor
Interaction Summary
Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Read the full Vitamin B6 + Carbidopa, Levodopa interactionCarbidopa, Levodopa, EntacaponeStalevo
How Carbidopa, Levodopa, Entacapone interacts with BCAA Hyperblend — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Levodopa Minor
Interaction Summary
Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Read the full Vitamin B6 + Carbidopa, Levodopa, Entacapone interactionLevodopaInbrija, Larodopa
How Levodopa interacts with BCAA Hyperblend — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Levodopa Minor
Interaction Summary
Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Read the full Vitamin B6 + Levodopa interactionLevodopa, CarbidopaDuodopa
How Levodopa, Carbidopa interacts with BCAA Hyperblend — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Levodopa Minor
Interaction Summary
Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Read the full Vitamin B6 + Levodopa, Carbidopa interactionEach ingredient & the kinds of drugs it affects
For each ingredient in BCAA Hyperblend with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Vitamin B6
Amiodarone (Cordarone)
Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.
Antihypertensive Drugs
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.
Phenobarbital (Luminal)
High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.
Phenytoin (Dilantin)
High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.
Levodopa
Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.
Brand information
Manufacturer and brand details for BCAA Hyperblend, from the product label.
Top Secret Nutrition
See all Top Secret Nutrition products- Name
- Top Secret Nutrition
- Street Address
- 11341 Interchange Circle South
- City
- Miramar
- State
- Florida
- ZipCode
- 33025
- Phone Number
- (877)-633-3830
- Web Address
- www.topsecretnutrition.com
BCAA Hyperblend by Top Secret Nutrition: Common Questions
Does BCAA Hyperblend by Top Secret Nutrition interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant?
What is L-leucine and what does it do?
Is vitamin B6 safe at the dose in this product?
What is the proprietary anabolic and rapid absorption blend?
What are the inactive ingredients, and do they matter?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if BCAA Hyperblend is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind BCAA Hyperblend’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
BCAA Hyperblend's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 32 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Vitamin B6 32 references
- Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
- Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
- Geerling BJ, Dagnelie PC, Badart-Smook A, et al. Diet as a risk factor for the development of ulcerative colitis. Am J Gastroenterol 2000;95:1008-13. PubMed
- South M. Neonatal seizures after pyridoxine use -- reply. Lancet 1999;354:2083. PubMed
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
- Baxter P, Aicardi J. Neonatal seizures after pyridoxine use. Lancet 1999;354:2082-3. PubMed
- Bendich A, Cohen M. Vitamin B6 safety issues. Ann N Y Acad Sci 1990;585:321-30.
- Schaumburg H, Kaplan J, Windebank A. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. N Engl J Med 1983;309:445-8. PubMed
- Gordon N. Pyridoxine dependency: an update. Dev Med Child Neurol 1997;39:63-5. PubMed
- Lewis PJ. Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome. BMJ 1995;310:1534. PubMed
- Kaufman G. Pyridoxine against amiodarone-induced photosensitivity (letter). Lancet 1984;1:51-2. PubMed
- Mulrow JP, Mulrow CD, McKenna WJ. Pyridoxine and amiodarone-induced photosensitivity. Ann Intern Med 1985;103:68-9. PubMed
- Kawada A, Kashima A, Shiraishi H, et al. Pyridoxine-induced photosensitivity and hypophosphatasia. Dermatology 2000;201:356-60.. PubMed
- Vasile A, Goldberg R, Kornberg B. Pyridoxine toxicity: report of a case. J Am Osteopath Assoc 1984;83:790-1. DOI
- Hansson O, Sillanpaa M. Pyridoxine and serum concentration of phenytoin and phenobarbitone. Lancet 1976;1:256. DOI
- Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
- Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai 2007;90:15-20.
- Hatzitolios, A., Iliadis, F., Katsiki, N., and Baltatzi, M. Is the anti-hypertensive effect of dietary supplements via aldehydes reduction evidence based? A systematic review. Clin Exp.Hypertens. 2008;30(7):628-639. PubMed
- Vasdev, S., Ford, C. A., Parai, S., Longerich, L., and Gadag, V. Dietary vitamin B6 supplementation attenuates hypertension in spontaneously hypertensive rats. Mol.Cell Biochem. 1999;200(1-2):155-162.
- de, Vogel S., Dindore, V., van, Engeland M., Goldbohm, R. A., van den Brandt, P. A., and Weijenberg, M. P. Dietary folate, methionine, riboflavin, and vitamin B-6 and risk of sporadic colorectal cancer. J Nutr 2008;138(12):2372-2378. PubMed
- Hagen, I., Nesheim, B. I., and Tuntland, T. No effect of vitamin B-6 against premenstrual tension. A controlled clinical study. Acta Obstet.Gynecol.Scand. 1985;64(8):667-670. PubMed
- Aybak, M., Sermet, A., Ayyildiz, M. O., and Karakilcik, A. Z. Effect of oral pyridoxine hydrochloride supplementation on arterial blood pressure in patients with essential hypertension. Arzneimittelforschung. 1995;45(12):1271-1273.
- Lal, K. J., Dakshinamurti, K., and Thliveris, J. The effect of vitamin B6 on the systolic blood pressure of rats in various animal models of hypertension. J Hypertens. 1996;14(3):355-363. PubMed
- Lauritzen CH, Reuter HD, Repges R, Bohnert K, and Schmidt U. Treatment of premenstrual tension syndrome with Vitex agnus castus. Controlled, double-blind study versus pyridoxine. Phytomed 1997;4(3):183-189. PubMed
- Fonseca VA, Lavery LA, Thethi TK, et al. Metanx in type 2 diabetes with peripheral neuropathy: A randomized trial. Am J Med 2013;126(2):141-9. PubMed
- Hankey GJ, Eikelboom JW, Yi Q, et al. Treatment with B vitamins and incidence of cancer in patients with previous stroke or transient ischemic attack: Results of a randomized placebo-controlled trial. Stroke 2012;43(6):1572-7. PubMed
- Hoyer-Kuhn H, Kohbrok S, Volland R, Franklin J, Hero B, Beck BB, Hoppe B. Vitamin B6 in primary hyperoxaluria I: first prospective trial after 40 years of practice. Clin J Am Soc Nephrol. 2014 Mar;9(3):468-77. PubMed
- Mahmoud A, Tabassum S, Al Enazi S, et al. Amelioration of levetiracetam-induced behavioral side effects by pyridoxine. A randomized double blind controlled study. Pediatr Neurol 2021;119:15-21. PubMed
- Gupta M, Gallante B, Bamberger JN, et al. Prospective randomized evaluation of idiopathic hyperoxaluria treatments. J Endourol 2021;35(12):1844-1851. PubMed
- Li H, Chen M, Liang S, et al. Excessive vitamin B6 during treatment is related to poor prognosis of patients with nasopharyngeal carcinoma: A U-shaped distribution suggests low dose supplement. Clin Nutr 2021;40(4):2293-2300. PubMed
- Tanigawa J, Nabatame S, Tominaga K, et al. High-dose pyridoxine treatment for inherited glycosylphosphatidylinositol deficiency. Brain Dev 2021;43(6):680-687. PubMed
- Committee on Practice Bulletins-Obstetrics. ACOG Practice Bulletin No. 189: Nausea And Vomiting Of Pregnancy. Obstet Gynecol. 2018;131(1):e15-e30. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC