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Dietary supplement

Beetroot 1300 mg Ingredients & Drug Interactions

by eXplicit Supplements

Beetroot 1300 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Beetroot 1300 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Beetroot 1300 mg is a dietary supplement by eXplicit Supplements with 1 active ingredient. Its ingredients are commonly taken for high blood pressure, exercise and athletic performance, heart and circulation support.Based on those ingredients, 861 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beet, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Beetroot 1300 mg by eXplicit Supplements

Ask about any prescription or over-the-counter medication and we check it for interactions with Beetroot 1300 mg by eXplicit Supplements — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Beetroot 1300 mg by eXplicit Supplements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product is a straightforward single-ingredient supplement: 1,300 mg of beet powder per capsule. The powder comes from the beet plant and contains betanin and other compounds naturally present in the vegetable.

The capsule itself is made from cellulose, with rice flour and magnesium stearate added as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: exercise and athletic performance support.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Exercise-induced muscle soreness, Muscle strength, Endurance, Stamina — and 1 related terms.
  • The strongest evidence on file: Beet is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Beet is rated "Possibly Effective" for Exercise-induced muscle soreness.
  • Also on file: Beet is rated "Insufficient Reliable Evidence To Rate" for Muscle strength, Exercise-induced muscle damage.

The evidence for beet is mixed. It's possibly effective for athletic performance and for reducing exercise-induced muscle soreness — meaning small studies suggest a benefit, but we'd like to see more research.

For chronic obstructive pulmonary disease (COPD), it appears possibly ineffective. The data on beet for cholesterol levels and cognitive function isn't established enough in what we hold to rate either way.

The evidence, ingredient by ingredient Beet

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beet is a food most people eat without trouble, and short-term medicinal use appears generally well tolerated. The most common side effect is harmless red or dark-colored stools and urine — that's just the pigment passing through.

However, concentrated beet supplements lack the safety testing that whole food has, so use caution and don't exceed recommended doses. In rare cases, very large amounts have been linked to low blood calcium (hypocalcemia) and kidney damage, and there's one reported case of a patient on blood thinners who developed black stools after taking beet pills, though the risk of serious bleeding was deemed low.

Pregnancy and lactation safety data isn't on file for beet supplements.

Side effects, ingredient by ingredient Beet

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beet.
  • The most serious interaction on file is rated Moderate.
  • For scale: 862 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications against this product if you take drugs metabolized by the liver enzyme CYP3A4 — this is a large group including many heart, cholesterol, and immune medications, and beet may raise their blood levels (Moderate severity). Also double-check if you're on medications metabolized by CYP1A2, which beet may weaken (Minor), or blood pressure medications, since beet contains nitrates (Minor).

Use the search tool on this page with your exact medication names.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Beet powder might help with athletic performance or exercise recovery, but it's a one-ingredient product with meaningful interactions with hundreds of medications — especially those your liver processes through the CYP3A4 pathway. If you take any prescription drugs, check them here first.

Talk to your pharmacist before you add this to your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Beetroot 1300 mg, straight from the product label.

Brand eXplicit Supplements
Barcode (UPC) 632726066383
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Dec 21, 2024
DSLD ID 310008
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Beetroot 1300 mg by eXplicit Supplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
632726066383
IngredientAmount% DV
Beet, Powder1300 mg--

Other ingredients: Cellulose, Rice Flour, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Please recycle this container

Come check out our other products: www.explicitsupplements.com

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take one (2) veggie capsule twice a day. For best results take 20-30 min before a meal with 8oz glass of water or as directed by your healthcare provider.

Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

All natural

Made with All Natural Ingredients No Artificial Flavors No preservatives No soy, dairy or egg ingredients

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Made with All Natural Ingredients No Artificial Flavors No preservatives GMP Good Manufacturing Practice FDA Registered Facility Made in the USA

Formula

Beetroot 1300 mg per serving

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Beetroot 1300 mg by eXplicit Supplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Beetroot 1300 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Beetroot 1300 mg by eXplicit Supplements

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Beet, Powder

Interacts with
861 drugs
1300 mg per serving

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some peopl...

Beet, Powder monograph & interactions

Other (inactive) ingredients: Cellulose, Rice Flour, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Beetroot 1300 mg by eXplicit Supplements Drug Interactions

Want to check YOUR meds against Beetroot 1300 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
861Drugs
643 Moderate 218 Minor

Ingredients driving the most interactions

Beet, Powder 861

Individual Drug Interactions

The ingredients in Beetroot 1300 mg interact with 861 drugs. Click any drug to see the details.

1 of the 1 ingredient in Beetroot 1300 mg interact with drugs. Each result below shows which ingredient is responsible. Beet, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Beetroot 1300 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Beet, Powder3 drug types · 861 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, beet might increase the levels of CYP3A4 substrates.
In vitro research suggests that betanin, the major pigment in beet, competitively inhibits CYP3A4 in a dose-dependent manner similarly to strong CYP3A4 inhibitor ketoconazole.

Likelihood Possible Evidence D
Antihypertensive Drugs

Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure. However, a study published in the European Journal of Clinical Nutrition using concentrated beetroot juice found no significant impact on blood pressure or heart rate in different age groups. Other small clinical studies suggest that while beet consumption might transiently lower blood pressure due to vessel dilation, there's no consistent evidence of a lasting effect. Overall, the theoretical risk of reduced blood pressure due to beet's nitrate content exists, but studies generally indicate a low and temporary impact rather than a sustained decrease.

Likelihood Possible Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research suggests that beet induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Beet, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Beetroot 1300 mg, from the product label.

eXplicit Supplements

See all eXplicit Supplements products
Name
iXanda Inc.
City
Clarence
State
NY
ZipCode
14032
Phone Number
(716)-701-4092
Web Address
www.explicitsupplements.com
Pharmacist Counseling Corner

Beetroot 1300 mg by eXplicit Supplements: Common Questions

Does Beetroot 1300 mg by eXplicit Supplements interact with any medications?
Yes. Based on its ingredients, Beetroot 1300 mg has a known interaction with 861 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Beetroot 1300 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will beet supplement turn my urine and stool red?
Very likely. Red or dark-colored urine and stools are the most common effect and are completely harmless — it's just the beet's natural pigment. Some people also report black stools. It's not a sign anything is wrong.
Does this actually improve athletic performance?
The evidence suggests it possibly does, based on small studies, but we'd need larger research to be confident. If you're an athlete or train regularly, it might be worth a try — just check your medications first.
Is beet supplement safe to take long-term?
Beet as a food is fine to eat regularly, but concentrated supplements don't have much long-term safety data, so caution is warranted. Stick to the recommended dose and avoid taking very large amounts, which in rare cases have caused low blood calcium and kidney issues.
Can I take this if I'm pregnant or breastfeeding?
We don't have safety data on file for beet supplements during pregnancy or lactation. Talk to your doctor or pharmacist for personalized advice — they can weigh what's known about the risks and benefits for your situation.
What is betanin, and why does it matter?
Betanin is the main pigment that gives beets their deep red color. It's responsible for most of beet's biological effects, including how it interacts with liver enzymes that break down your medications — that's why it matters for your drug interactions.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Beetroot 1300 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Beetroot 1300 mg label
Go deeper

The Full Monographs Behind Beetroot 1300 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beet

Interacts with 861 drugs

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some people. It is generally safe as a food, but s...

Read the full Beet monograph →
Sources

Sources & How We Checked

Beetroot 1300 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beet 14 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Clifford T, Berntzen B, Davison GW, et al. Effects of beetroot juice on recovery of muscle function and performance between bouts of repeated sprint exercise. Nutrients 2016;8. pii: E506. PubMed
  3. Siervo M, Lara J, Ogbonmwan I, Mathers JC. Inorganic nitrate and beetroot juice supplementation reduces blood pressure in adults: a systematic review and meta-analysis. J Nutr 2013;143:818-26. PubMed
  4. Clifford T, Howatson G, West DJ, Stevenson EJ. Beetroot juice is more beneficial than sodium nitrate for attenuating muscle pain after strenuous eccentric-bias exercise. Appl Physiol Nutr Metab. 2017;42(11):1185-1191. PubMed
  5. Clifford T, Bell O, West DJ, Howatson G, Stevenson EJ. The effects of beetroot juice supplementation on indices of muscle damage following eccentric exercise. Eur J Appl Physiol. 2016;116(2):353-62. PubMed
  6. Wylie LJ, Kelly J, Bailey SJ, et al. Beetroot juice and exercise: pharmacodynamic and dose-response relationships. J Appl Physiol (1985). 2013;115(3):325-36. PubMed
  7. Garnacho-Castaño MV, Palau-Salvà G, Cuenca E, et al. Effects of a single dose of beetroot juice on cycling time trial performance at ventilatory thresholds intensity in male triathletes. J Int Soc Sports Nutr. 2018;15(1):49. PubMed
  8. Rasica L, Porcelli S, Marzorati M, et al. Ergogenic effects of beetroot juice supplementation during severe-intensity exercise in obese adolescents. Am J Physiol Regul Integr Comp Physiol. 2018;315(3):R453-R460. PubMed
  9. Henrohn D, Björkstrand K, Lundberg JO, et al. Effects of oral supplementation with nitrate-rich beetroot juice in patients with pulmonary arterial hypertension-results from BEET-PAH, an exploratory randomized, double-blind, placebo-controlled, crosso
  10. Serra-Payá N, Garnacho-Castaño MV, Sánchez-Nuño S, et al. The relationship between resistance exercise performance and ventilatory efficiency after beetroot juice intake in well-trained athletes. Nutrients 2021;13(4):1094. PubMed
  11. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  12. Hemmatinafar M, Zaremoayedi L, Koushkie Jahromi M, et al. Effect of Beetroot Juice Supplementation on Muscle Soreness and Performance Recovery after Exercise-Induced Muscle Damage in Female Volleyball Players. Nutrients 2023;15(17):3763. PubMed
  13. Lim SH, Bae S, Lee HS, Han HK, Choi CI. Effect of Betanin, the Major Pigment of Red Beetroot (Beta vulgaris L.), on the Activity of Recombinant Human Cytochrome P450 Enzymes. Pharmaceuticals (Basel) 2023;16(9):1224. PubMed
  14. Oscherwitz M, Tamayo RM, Heudebert A, Centor R. A Case of Pseudo-Hematochezia from Beet Supplement Ingestion. Am J Med 2023;136(9):e177-e178. PubMed

See these in context on the Beet monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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