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Dietary supplement

Lutein with Lutemax 2020 20 mg Ingredients & Drug Interactions

by Doctor's Best

Lutein with Lutemax 2020 20 mg label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lutein with Lutemax 2020 20 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lutein with Lutemax 2020 20 mg is a dietary supplement by Doctor's Best with 2 active ingredients. Its ingredients are commonly taken for eye and macular health, age-related macular degeneration (amd), protection from blue light.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Zeaxanthin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Lutein with Lutemax 2020 20 mg by Doctor's Best

Ask about any prescription or over-the-counter medication and we check it for interactions with Lutein with Lutemax 2020 20 mg by Doctor's Best — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Lutein with Lutemax 2020 20 mg by Doctor's Best

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This softgel contains two active ingredients: lutein and zeaxanthin, both carotenoids (plant pigments) that concentrate in the eye and are linked to visual health. The product delivers 20 mg of Lutemax 2020, a patented lutein-zeaxanthin blend.

The softgel capsule itself is made with sunflower oil as the carrier.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support eye health and visual function.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Central serous retinopathy, Choroideremia, Diabetic retinopathy — and 4 related terms.
  • The strongest evidence on file: Lutein is rated "Possibly Effective" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Lutein is rated "Possibly Effective" for Cataracts.
  • Also on file: Zeaxanthin is rated "Possibly Effective" for Age-related macular degeneration (AMD).

Lutein is possibly effective for age-related macular degeneration (AMD) and cataracts, two common eye conditions in older adults. Zeaxanthin is also possibly effective for AMD.

The evidence for both ingredients in slowing age-related cognitive decline or helping Alzheimer disease is insufficient—meaning the research just isn't there yet. Several other conditions listed (asthma, breast cancer, retinitis pigmentosa) either lack reliable evidence or show the ingredient may not help.

The evidence, ingredient by ingredient Zeaxanthin Lutein

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both lutein and zeaxanthin are generally well tolerated at typical supplement doses. Lutein, in particular, has been used at up to 20 mg daily without reported adverse effects.

For pregnancy and lactation, the data for both ingredients is rated Likely Safe, though the facts note that while these carotenoids occur naturally in food and breast milk, the safety of concentrated supplements at higher doses during pregnancy or breastfeeding hasn't been thoroughly studied. If you're pregnant or nursing, talk with your doctor or pharmacist about whether to take this product.

Side effects, ingredient by ingredient Zeaxanthin Lutein

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Zeaxanthin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs (insulin, metformin, sulfonylureas, GLP-1 agonists, or others), check your specific medication below before starting this product. Zeaxanthin may increase the risk of low blood sugar.

No other interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a straightforward two-ingredient eye-health supplement backed by possibly-effective evidence for AMD and cataracts. If you take an antidiabetes medication, check your specific drug with the tool below first—zeaxanthin has a theoretical Moderate interaction.

Otherwise, it's generally well tolerated, but run it by your own doctor or pharmacist before you start, especially if you're pregnant, nursing, or on other medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lutein with Lutemax 2020 20 mg, straight from the product label.

Brand Doctor's Best
Barcode (UPC) 753950003699
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Jul 21, 2022
DSLD ID 269662
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lutein with Lutemax 2020 20 mg by Doctor's Best, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
60
UPC/BARCODE
753950003699
IngredientAmount% DV
Zeaxanthin4 mg--
Lutein20 mg--

Other ingredients: Sunflower Oil, Softgel capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Doctor’s Best Lutein with Lutemax 2020 contains a highly researched, optimal ratio of lutein and zeaxanthin to help protect your eyes from harmful high energy blue light in everyday surroundings including most digital screens, sunlight, and indoor lighting. This natural extract from Marigold flower helps neutralize free radicals to support visual function, and eye health from frequent use of digital devices.

Lutein with Lutemax 2020 Lutein & Zeaxanthin

Formulation

Helps support visual function Helps protect eyes from harmful high energy blue light in everyday surroundings Helps support eye health when using digital devices Helps neutralize free radicals

Helps support visual function and neutralize free radicals

Non-GMO Gluten free

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

Science-Based Nutrition Doctor's Best

Lutemax 2020 is a trademark of OmniActive Health Technologies Ltd.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Adult Use: Take 1 softgel daily, with or without food, as recommended by a nutritionally-informed physician.

Storage

Store in a cool dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lutein with Lutemax 2020 20 mg by Doctor's Best label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lutein with Lutemax 2020 20 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lutein with Lutemax 2020 20 mg by Doctor's Best

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Zeaxanthin

Interacts with
86 drugs
4 mg per serving Form: Lutemax 2020 Marigold flower extract

Zeaxanthin is a carotenoid pigment that, along with lutein, concentrates in the macula of the eye and may help support long-term eye health. The stron...

Zeaxanthin monograph & interactions

Lutein

No known
interactions
20 mg per serving Form: Lutemax 2020, Marigold flowers extract

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...

Lutein monograph & interactions

Other (inactive) ingredients: Sunflower Oil, Softgel capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lutein with Lutemax 2020 20 mg by Doctor's Best Drug Interactions

Want to check YOUR meds against Lutein with Lutemax 2020 20 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Zeaxanthin 86

Individual Drug Interactions

The ingredients in Lutein with Lutemax 2020 20 mg interact with 86 drugs. Click any drug to see the details.

1 of the 2 ingredients in Lutein with Lutemax 2020 20 mg interact with drugs. Each result below shows which ingredient is responsible. Zeaxanthin

Each ingredient & the kinds of drugs it affects

For each ingredient in Lutein with Lutemax 2020 20 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Zeaxanthin1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
In an animal diabetic model, zeaxanthin has hypoglycemic effects. However, population research has found that increasing intake of dietary zeaxanthin plus lutein does not decrease the risk of developing type 2 diabetes.

Likelihood Possible Evidence D
Zeaxanthin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lutein with Lutemax 2020 20 mg, from the product label.

Doctor's Best

See all Doctor's Best products
Name
Doctor's Best, Inc.
State
California
ZipCode
92612
Phone Number
(800) 777-2474
Web Address
www.drbvitamins.com
Pharmacist Counseling Corner

Lutein with Lutemax 2020 20 mg by Doctor's Best: Common Questions

Does Lutein with Lutemax 2020 20 mg by Doctor's Best interact with any medications?
Yes. Based on its ingredients, Lutein with Lutemax 2020 20 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lutein with Lutemax 2020 20 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my macular degeneration?
Lutein and zeaxanthin are both possibly effective for age-related macular degeneration based on available evidence. That means they show promise, but they're not proven to reverse existing damage. Talk with your eye doctor about whether adding this supplement fits into your overall plan.
Can I take this if I'm pregnant?
Both lutein and zeaxanthin are rated Likely Safe in pregnancy, and these carotenoids occur naturally in food. However, safety data on concentrated supplements during pregnancy isn't well studied. Check with your doctor or pharmacist about whether this product is right for you right now.
What's in the capsule besides the active ingredients?
The softgel is made with sunflower oil as a carrier to deliver the lutein and zeaxanthin. There are no other active ingredients or additives listed.
Can I take this if I'm diabetic?
Zeaxanthin may theoretically increase the risk of low blood sugar if you're on antidiabetes medication. Use the interaction checker on this page to look up your specific drug, then talk with your doctor or pharmacist about whether to take it.
Are there any side effects?
Lutein at doses up to 20 mg daily has not caused adverse effects in studies. Both ingredients are generally well tolerated at typical supplement amounts.
Can I take this while breastfeeding?
Both lutein and zeaxanthin are rated Likely Safe, and lutein naturally occurs in breast milk. However, safety data on higher-dose supplements while breastfeeding hasn't been well studied. Talk with your doctor or pharmacist about whether to take this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lutein with Lutemax 2020 20 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lutein with Lutemax 2020 20 mg label
Go deeper

The Full Monographs Behind Lutein with Lutemax 2020 20 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Zeaxanthin

Interacts with 86 drugs

Zeaxanthin is a carotenoid pigment that, along with lutein, concentrates in the macula of the eye and may help support long-term eye health. The strongest evidence relates to slowing progres...

Read the full Zeaxanthin monograph → Herb & supplement monograph

Lutein

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help slow progression of age-related macular...

Read the full Lutein monograph →
Sources

Sources & How We Checked

Lutein with Lutemax 2020 20 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Zeaxanthin 4 references
  1. Montonen J, Knekt P, Jarvinen R, Reunanen A. Dietary antioxidant intake and risk of type 2 diabetes. Diabetes Care 2004;27:362-6. PubMed
  2. Leermakers ET, Darweesh SK, Baena CP, et al. The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis. Am J Clin Nutr 2016;103(2):481-94. PubMed
  3. Kou L, Du M, Zhang C, Dai Z, Li X, Zhang B. The Hypoglycemic, Hypolipidemic, and Anti-Diabetic Nephritic Activities of Zeaxanthin in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats. Appl Biochem Biotechnol 2017;182(3):944-955. PubMed
  4. Xu X, Zhao X, Berde Y, Low YL, Kuchan MJ. Milk and Plasma Lutein and Zeaxanthin Concentrations in Chinese Breast-Feeding Mother-Infant Dyads With Healthy Maternal Fruit and Vegetable Intake. J Am Coll Nutr 2019;38(2):179-184. PubMed

See these in context on the Zeaxanthin monograph →

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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