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Dietary supplement

Betula Pendula Ingredients & Drug Interactions

by UNDA Gemmo

Betula Pendula label
See full label image
Liquid Category: Botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Betula Pendula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Betula Pendula is a dietary supplement by UNDA Gemmo with 1 active ingredient. Its ingredients are commonly taken for urinary tract and 'flushing' support, joint pain and arthritis, mild fluid retention (diuretic).Based on those ingredients, 75 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Birch (Betula pendula) sap extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Betula Pendula by UNDA Gemmo

Ask about any prescription or over-the-counter medication and we check it for interactions with Betula Pendula by UNDA Gemmo — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Betula Pendula by UNDA Gemmo

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: birch (Betula pendula) sap extract. Birch sap has been used traditionally to support joint health and scalp health, though the evidence for those uses isn't yet established in our data.

The liquid also contains glycerin, ethanol, and purified water as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Birch product and its label doesn't state a use — see Birch's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for birch sap extract isn't established in our data. We hold insufficient reliable evidence to rate it for joint pain, hair loss (alopecia), or dandruff — the three uses listed in the facts.

That doesn't mean it doesn't work; it means the clinical trials we have access to haven't been robust enough to draw a firm conclusion either way.

The evidence, ingredient by ingredient Birch

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Birch is generally well tolerated in food-like amounts, but allergy is a real concern. Birch and birch pollen can trigger allergic reactions in sensitive people.

In rare cases, applying birch-based creams has caused allergic contact dermatitis; fresh birch sap and crushed leaves can do the same. If you have a birch pollen allergy, be cautious with this supplement.

During pregnancy, there isn't enough safety data, so birch supplements are best avoided. The same goes for breastfeeding — safety hasn't been established.

Talk with your doctor or pharmacist about whether this is right for you if you're pregnant or nursing.

Side effects, ingredient by ingredient Birch

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Birch.
  • The most serious interaction on file is rated Minor.
  • For scale: 75 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take diuretic drugs (water pills for blood pressure or fluid retention), check your specific medication with the search tool before starting this product. Birch might interfere with how well your diuretic works.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Betula Pendula is a birch sap extract marketed for joint and scalp health, but the evidence for those uses isn't yet solid. If you take a diuretic, check with your own doctor or pharmacist first — there's a minor interaction risk.

And if you have a birch pollen allergy or are pregnant or breastfeeding, this one's best avoided.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 26, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Betula Pendula, straight from the product label.

Brand UNDA Gemmo
Barcode (UPC) 88319630830
Net contents 4.2 fl. Oz.; 125 mL
Market status On market
Date entered into DSLD Dec 26, 2020
DSLD ID 241184
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Betula Pendula by UNDA Gemmo, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1.25 mL
Maximum serving Sizes:
1.25 mL
Servings per container
100
UPC/BARCODE
88319630830
IngredientAmount% DV
Birch (Betula pendula) sap extract1.25 mL--

Other ingredients: Glycerin, Ethanol, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended Dose: Adults and children (over 12 years): Take 50 drops (1.25 ml) three times daily in a small amount of water or as recommended by your healthcare practitioner. Drink plenty of water.

Precautions

Risk Information: If you are pregnant or breastfeeding, do not use, unless directed by your healthcare practitioner.

Formula

Succus sap

FDA Statement of Identity

Dietary Supplement

General Statements

Seroyal UNDA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Betula Pendula by UNDA Gemmo label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Betula Pendula label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Betula Pendula by UNDA Gemmo

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1.25 mL Dosage formLiquid Servings per container100 Amounts shown are per serving.

Birch (Betula pendula) sap extract

Interacts with
75 drugs
1.25 mL per serving

Birch is a tree whose leaves, bark, and sap are used in traditional remedies, most often as a mild diuretic or for joint and urinary complaints. Solid...

Birch (Betula pendula) sap extract monograph & interactions

Other (inactive) ingredients: Glycerin, Ethanol, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Betula Pendula by UNDA Gemmo Drug Interactions

Want to check YOUR meds against Betula Pendula?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
75Drugs
75 Minor

Ingredients driving the most interactions

Birch (Betula pendula) sap extract 75

Individual Drug Interactions

The ingredients in Betula Pendula interact with 75 drugs. Click any drug to see the details.

1 of the 1 ingredient in Betula Pendula interact with drugs. Each result below shows which ingredient is responsible. Birch (Betula pendula) sap extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Betula Pendula with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Birch (Betula pendula) sap extract1 drug type · 75 drugs

Diuretic Drugs

Theoretically, birch might interfere with diuretic therapy.

Likelihood Possible Evidence D
Birch (Betula pendula) sap extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Betula Pendula, from the product label.

UNDA Gemmo

See all UNDA Gemmo products
Name
Seroyal USA
City
Pittsburg
State
PA
ZipCode
15275
Phone Number
1-888-737-6925
Pharmacist Counseling Corner

Betula Pendula by UNDA Gemmo: Common Questions

Does Betula Pendula by UNDA Gemmo interact with any medications?
Yes. Based on its ingredients, Betula Pendula has a known interaction with 75 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Betula Pendula contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does birch sap extract actually help with joint pain?
The evidence isn't established yet in our data. We hold insufficient reliable evidence to rate it for joint pain, so we can't say whether it works. If joint health is your goal, talk it over with your doctor to weigh this against options with clearer evidence.
Can I take this if I have a birch pollen allergy?
You should be cautious. Birch and birch pollen can trigger allergic reactions in sensitive people, and birch sap extract could pose a risk. Check with your doctor or pharmacist before starting, especially if your allergy is severe.
Is it safe to use while pregnant or breastfeeding?
No — there isn't enough safety data to know either way. Birch supplements are best avoided during pregnancy and while breastfeeding. Talk with your doctor or pharmacist about what's safe for you at this stage.
What's in this liquid besides the birch extract?
The inactive ingredients are glycerin, ethanol, and purified water — basically preservatives and a liquid base to deliver the extract.
Can birch sap extract cause side effects?
The main risk is an allergic reaction or allergic contact dermatitis, especially in people sensitive to birch pollen or birch products. A rash from applying birch-based creams or contact with fresh sap is possible but rare. If you have symptoms like itching or a rash, stop use and talk with your doctor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Betula Pendula label
Go deeper

The Full Monographs Behind Betula Pendula’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Birch

Interacts with 75 drugs

Birch is a tree whose leaves, bark, and sap are used in traditional remedies, most often as a mild diuretic or for joint and urinary complaints. Solid human evidence is limited, and birch is...

Read the full Birch monograph →
Sources

Sources & How We Checked

Betula Pendula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Birch 4 references
  1. Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
  2. Lahti, A. and Hannuksela, M. Immediate contact allergy to birch leaves and sap. Contact Dermatitis 1980;6(7):464-465. PubMed
  3. Allam JP, Wuestenberg E, Wolf H, et al. Immunologic response and safety in birch pollen sublingual versus oral vestibule immunotherapy: a pilot study. J Allergy Clin Immunol. 2014;133(6):1757-9.e3. PubMed
  4. Meyer-Hoffert U, Brasch J. Allergic contact dermatitis caused by betulin-containing triterpene extract from the outer bark of birch (Betula alba). Contact Dermatitis. 2013;68(6):382-3.

See these in context on the Birch monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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