Biotin Plus 5,000 mcg Ingredients & Drug Interactions
by Natrol
What is this page for?
First and foremost: checking Biotin Plus 5,000 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Biotin Plus 5,000 mcg is a dietary supplement by Natrol with 2 active ingredients. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Biotin Plus 5,000 mcg by Natrol
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This tablet contains two active ingredients. Biotin, a B vitamin, supports the health of hair, skin, and nails—it's the star at 5,000 micrograms per dose.
Lutein, a carotenoid found naturally in leafy greens, concentrates in the eye and helps protect vision as you age. The product also contains several inactive ingredients (binders, fillers, and capsule materials) including dicalcium phosphate, microcrystalline cellulose, alginate, stearic acid, and others that help hold the tablet together and keep it stable on the shelf.
Does it work?
Strong evidence
Biotin is likely effective for treating biotin deficiency—a real condition, though uncommon. For everything else on the label (hair, skin, nails, or general wellness), the evidence doesn't support it; studies suggest it's possibly ineffective for alopecia areata, and we don't have enough reliable evidence to rate it for that condition either.
Lutein shows some promise. It's possibly effective for age-related macular degeneration (AMD) and cataracts—both age-related eye conditions.
For other retinal conditions listed, the data suggests it's not effective.
How safe is it?
Well-documented data
Both biotin and lutein are generally well tolerated. Biotin is considered safe even at fairly high doses because your body flushes excess through urine.
One small note: very high-dose biotin (much higher than this product) has rarely been linked to mild diarrhea, and there's one isolated case report of a more serious reaction, though whether biotin alone was responsible is unclear. Lutein from food and typical supplement doses is safe for most adults.
Both ingredients are rated likely safe in pregnancy and lactation, though because long-term high-dose supplement safety for lutein during pregnancy or breastfeeding hasn't been extensively studied, it's worth discussing with your doctor if you're expecting or nursing and considering this product.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check in this product. You're clear to use it alongside your medications from an interaction standpoint—but as always, mention it to your doctor or pharmacist at your next visit just to keep your full medication picture on file.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
This product is a straightforward pair of ingredients with solid safety data and no documented drug interactions. It makes sense for someone with biotin deficiency or anyone interested in eye health support, though the evidence for biotin's effect on hair, skin, or nails is weak.
Talk it over with your doctor or pharmacist before starting, especially if you're pregnant, breastfeeding, or taking other supplements.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Biotin Plus 5,000 mcg, straight from the product label.
| Brand | Natrol |
|---|---|
| Barcode (UPC) | 047469071417 |
| Net contents | 60 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Jun 22, 2023 |
| DSLD ID | 287510 |
| Product type | Other Combinations |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Biotin Plus 5,000 mcg by Natrol, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Biotin | 5000 mcg | 16670% |
| Lutein | 10 mg | -- |
Other ingredients: Dicalcium Phosphate, Microcrystalline Cellulose, Alginate, Stearic Acid, Cellulose Gum, Gum Arabic, Silicon Dioxide, Pea Starch, Magnesium Stearate, Methylcellulose, Rosemary Extract, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Natrol Biotin Plus with Lutein: 5,000mcg Biotin- supports healthy hair, radiant skin and strong nails for those low in Biotin 10mg Lutein- clinical strength skincare shown to improve skin elasticity and hydration when taken daily
Plus clinical strength lutein for improved skin elasticity & hydration
Formulation
Helps support energy metabolism and aids in the conversation of food into energy
Beauty Supports healthy hair, skin & nails for those low in biotin
Extra strength
Vegetarian
No: Milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat, soybeans, yeast, artificial colors, flavors, added sugar or preservatives.
Precautions
Warning: Consult your healthcare professional prior to use if you have or suspect a medical condition, are taking prescription drugs, or are pregnant or lactating.
During use, advise your medical professional that you are taking Biotin before any laboratory tests.
Keep out of reach of children.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statement have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: Take 1 tablet, one time daily, with a meal.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Biotin Plus 5,000 mcg by Natrol label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Biotin Plus 5,000 mcg by Natrol
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Biotin
No knowninteractions
Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...
Biotin monograph & interactionsLutein
No knowninteractions
Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...
Lutein monograph & interactionsOther (inactive) ingredients: Dicalcium Phosphate, Microcrystalline Cellulose, Alginate, Stearic Acid, Cellulose Gum, Gum Arabic, Silicon Dioxide, Pea Starch, Magnesium Stearate, Methylcellulose, Rosemary Extract, Glycerin. These complete the product’s ingredient list but are not active constituents.
Biotin Plus 5,000 mcg by Natrol Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Biotin Plus 5,000 mcg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Biotin Plus 5,000 mcg, from the product label.
Natrol
See all Natrol products- Name
- Natrol LLC
- City
- Chatsworth
- State
- CA
- ZipCode
- 91311
- Phone Number
- 1-800-262-8765
- Web Address
- www.natrol.com
Biotin Plus 5,000 mcg by Natrol: Common Questions
Does Biotin Plus 5,000 mcg by Natrol interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does biotin actually help hair, skin, or nails?
What is lutein, and why is it in here?
Is this safe to take while pregnant or breastfeeding?
What are the side effects?
Can I take this with my other vitamins and supplements?
Is biotin really 5,000 mcg per tablet?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Biotin Plus 5,000 mcg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Biotin Plus 5,000 mcg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Biotin
Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get plenty from a normal diet, and true defi...
Read the full Biotin monograph → Herb & supplement monographLutein
Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help slow progression of age-related macular...
Read the full Lutein monograph →Sources & How We Checked
Biotin Plus 5,000 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 6 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Biotin 4 references
- Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
- Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
- Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed
Lutein 2 references
- Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
- Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC