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Dietary supplement

Primadophilus Fortify Women's Probiotic Ingredients & Drug Interactions

by Nature's Way

Primadophilus Fortify Women's Probiotic label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Primadophilus Fortify Women's Probiotic against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Primadophilus Fortify Women's Probiotic is a dietary supplement by Nature's Way with 2 active ingredients.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Primadophilus Fortify Women's Probiotic by Nature's Way

Ask about any prescription or over-the-counter medication and we check it for interactions with Primadophilus Fortify Women's Probiotic by Nature's Way — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Primadophilus Fortify Women's Probiotic by Nature's Way

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 7 active ingredients.
  • “Primadophilus Fortify Women's Proprietary Probiotic Blend” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “Lactobacilli:” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Bifidobacteria” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

Primadophilus Fortify Women's Probiotic contains 7 active ingredients — a proprietary blend of live probiotic bacteria. The checked strains include two forms of L. acidophilus (La-14 and NCFM), L. gasseri, and others in the Lactobacillus and Bifidobacterium families.

We don't have interaction data on file for L. plantarum, L. rhamnosus, L. casei, or B. lactis, so we couldn't evaluate those strains. The inactive ingredients are cellulose, a plant-derived capsule, magnesium stearate, and silica — standard capsule materials and fillers.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: digestive balance immunity and vaginal health.
  • We looked for evidence on: Antibiotic-associated diarrhea, Bacterial vaginosis, Common cold, Constipation, Diarrhea, Dyspepsia — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Bacterial vaginosis, Helicobacter pylori, Irritable bowel syndrome (IBS).
  • Also on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Constipation, Inflammatory bowel disease (IBD), Radiation-induced diarrhea.

L. acidophilus is possibly effective for irritable bowel syndrome, Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis, though the evidence is limited. It's considered possibly ineffective for atopic disease, and evidence is insufficient to rate it for acute respiratory distress syndrome.

L. gasseri hasn't yet shown sufficient reliable evidence for any of the conditions studied — including hay fever, aspirin-related stomach damage, asthma, bacterial vaginosis, common cold, or diarrhea. We don't have effectiveness data for the other strains in this blend.

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L. acidophilus and L. gasseri are generally well tolerated in healthy adults and children, though the data are limited. Because these are live microorganisms, there's theoretical concern that they might cause infection in some patients — L. acidophilus has been isolated in rare cases of serious infections like bacteremia, sepsis, and endocarditis, though most cases appear to stem from bacteria spreading from elsewhere in the body.

For pregnancy, L. acidophilus is rated possibly safe, but we don't have safety data on file for L. plantarum, L. rhamnosus, L. casei, or B. lactis during pregnancy or breastfeeding. Talk with your doctor or pharmacist about whether this product is appropriate for you.

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Lactobacillus Acidophilus, Lactobacillus Gasseri.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take antibiotic drugs — these can reduce the effectiveness of the live probiotic organisms in the supplement. Timing your doses separately can help.

No other drug interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Primadophilus Fortify Women's Probiotic is geared toward women's digestive and urinary health through a mix of live probiotic strains, with the strongest evidence behind L. acidophilus for a few specific conditions. If you take antibiotics, you'll need to space them apart from this supplement to get the full benefit of both.

Check your exact medications with the tool on this page, and discuss this product with your doctor or pharmacist before starting, especially if you have a weakened immune system or limited safety data applies to you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Primadophilus Fortify Women's Probiotic, straight from the product label.

Brand Nature's Way
Barcode (UPC) 033674113530
Net contents 7 Capsule(s)
Market status On market
Date entered into DSLD Nov 21, 2016
DSLD ID 66386
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Female (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Primadophilus Fortify Women's Probiotic by Nature's Way, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
033674113530
IngredientAmount% DV
Primadophilus Fortify Women's Proprietary Probiotic Blend0 NP--
Lactobacilli:0 NP--
L. acidophilus [La-14],0 NP--
L. plantarum [Lp-115]0 NP--
L. acidophilus [NCFM]0 NP--
L. rhamnosus [Lr-32]0 NP--
L. gasseri [Lg-36]0 NP--
L. casei [Lc-11]0 NP--
Bifidobacteria0 NP--
B. lactis [Bl-04]0 NP--

Other ingredients: Cellulose, plant-derived Capsule, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

With Probiotic bonus pack

7 Capsules (1 week)

Free sample. Not for resale.

30 Billion live cultures

FDA Statement of Identity

Probiotic Supplement

General

LBN11353.10 BLK8586E, BLK8832

Formula

Primadophilus Fortify Women’s Probiotic provides 30 billion live cultures to support digestive balance, immunity and vaginal health.

Suggested/Recommended/Usage/Directions

Recommendation: Take 1 capsule daily. May be taken at any time, with or without food.

Precautions

If taking any medications, consult a healthcare professional before use.

Keep out of reach of children.

Brand IP Statement(s)

2016

NCFM and Bl-04 are trademarks of DuPont. In the USA, NCFM is a trademark of the North Carolina Agriculture Foundation, Inc. NCFM and Bl-04 are used under license.

Formulation

Gluten free. No artificial colors, flavors or preservatives.

Storage

Store in dry place at 73(0)F (23(0)C) or below. May be refrigerated.

FDA Disclaimer Statement

This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Primadophilus Fortify Women's Probiotic by Nature's Way label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Primadophilus Fortify Women's Probiotic label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Primadophilus Fortify Women's Probiotic by Nature's Way

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Primadophilus Fortify Women's Proprietary Probiotic Blend

0 NP per serving
  • › Lactobacilli:
  • › Bifidobacteria

Other (inactive) ingredients: Cellulose, Plant-derived Capsule, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Primadophilus Fortify Women's Probiotic by Nature's Way Drug Interactions

Want to check YOUR meds against Primadophilus Fortify Women's Probiotic?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Individual Drug Interactions

The ingredients in Primadophilus Fortify Women's Probiotic interact with 182 drugs. Click any drug to see the details.

0 of the 2 ingredients in Primadophilus Fortify Women's Probiotic interact with drugs. Each result below shows which ingredient is responsible.

Each ingredient & the kinds of drugs it affects

For each ingredient in Primadophilus Fortify Women's Probiotic with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

The maker

Brand information

Manufacturer and brand details for Primadophilus Fortify Women's Probiotic, from the product label.

Nature's Way

See all Nature's Way products
Name
Nature's Way Brands, LLC
City
Green Bay
State
WI
ZipCode
54311
Phone Number
1-800-962-8873
Web Address
fortifyprobiotics.com
Pharmacist Counseling Corner

Primadophilus Fortify Women's Probiotic by Nature's Way: Common Questions

Does Primadophilus Fortify Women's Probiotic by Nature's Way interact with any medications?
Yes. Based on its ingredients, Primadophilus Fortify Women's Probiotic has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Primadophilus Fortify Women's Probiotic contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on antibiotics?
You can take both, but not at the same time. Antibiotics can kill off the live probiotic organisms in this supplement, so separate your doses — your doctor or pharmacist can advise you on the best spacing. This is especially important if you want the probiotics to help prevent antibiotic-associated diarrhea.
Is this safe during pregnancy?
L. acidophilus is rated possibly safe in pregnancy, but we don't have enough data on the other strains in this blend. Talk with your doctor or pharmacist for personalized advice before taking it during pregnancy.
What side effects should I watch for?
Most people tolerate it well, but some experience uncommon gastrointestinal side effects like stomach discomfort, gas, bloating, or diarrhea. Rash and itching have been reported in rare cases, though it's unclear which ingredient might have caused them. If you develop signs of infection or serious symptoms, seek medical attention right away.
Does this really help with bacterial vaginosis?
L. acidophilus is possibly effective for bacterial vaginosis based on available evidence, though research is still limited. L. gasseri hasn't yet shown sufficient evidence for this condition. Your doctor can tell you whether this product is worth trying for your situation.
What are the inactive ingredients?
The capsule contains cellulose, magnesium stearate, and silica — standard fillers and binders with no active role. The capsule itself is plant-derived.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Primadophilus Fortify Women's Probiotic is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Primadophilus Fortify Women's Probiotic label
Sources

Sources & How We Checked

Primadophilus Fortify Women's Probiotic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 27 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Lactobacillus Gasseri 12 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Ramachandran L, Dontaraju VS, Patel K. Lactobacillus-associated spontaneous bacterial peritonitis in a liver cirrhosis patient on probiotics. Cureus. 2020;12(12):e11896. PubMed
  3. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  4. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
  5. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
  6. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
  7. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
  8. Ramos-Coria D, Canto-Losa J, Carrillo-Vázquez D, Carbajal-Morelos L, Estrada-León R, Corona-Rodarte E. Lactobacillus gasseri liver abscess and bacteremia: a case report. BMC Infect Dis 2021;21(1):518. PubMed
  9. Elikowski W, Malek-Elikowska M, Lisiecka M, Bodora A, Wisniewska K, Oko-Sarnowska Z. Lactobacillus gasseri endocarditis on the aortic valve bioprosthesis - a case report. Pol Merkur Lekarski 2017;43(257):220-223.
  10. Esquibel A, Dababneh AS, Palraj BR. Lactobacillus gasseri causing bilateral empyema. Case Rep Infect Dis 2017;2017:4895619.
  11. Tleyjeh IM, Routh J, Qutub MO, Lischer G, Liang KV, Baddour LM. Lactobacillus gasseri causing Fournier's gangrene. Scand J Infect Dis 2004;36(6-7):501-3. PubMed
  12. Dickgiesser U, Weiss N, Fritsche D. Lactobacillus gasseri as the cause of septic urinary infection. Infection 1984;12(1):14-6. PubMed

See these in context on the Lactobacillus Gasseri monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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