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Dietary supplement

Black Cherry Concentrate Ingredients & Drug Interactions

by GNC Natural Brand

Black Cherry Concentrate label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Black Cherry Concentrate against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Black Cherry Concentrate is a dietary supplement by GNC Natural Brand with 1 active ingredient. Its ingredients are commonly taken for cough, bronchitis and respiratory irritation, sore throat.Based on those ingredients, 643 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Black Cherry concentrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Black Cherry Concentrate by GNC Natural Brand

Ask about any prescription or over-the-counter medication and we check it for interactions with Black Cherry Concentrate by GNC Natural Brand — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Black Cherry Concentrate by GNC Natural Brand

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: black cherry concentrate. Black cherry has been used traditionally in herbal medicine, though the research supporting its effectiveness for specific purposes isn't established in our data.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Wild Cherry product and its label doesn't state a use — see Wild Cherry's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't have effectiveness evidence on file for black cherry concentrate for any condition.

The evidence, ingredient by ingredient Wild Cherry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Black cherry is generally considered safe in the small amounts found in over-the-counter cough products. However, the plant contains compounds that can break down into cyanide, so large amounts pose a real risk.

One documented case involved a woman who consumed about 300 grams of wild cherries steeped in alcohol and developed severe symptoms — headache, nausea, vomiting, confusion, difficulty breathing, and eventually coma. The safety data advises against use during pregnancy and breastfeeding because of the cyanide risk and lack of established safety data.

Side effects, ingredient by ingredient Wild Cherry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Wild Cherry.
  • The most serious interaction on file is rated Moderate.
  • For scale: 644 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Wild cherry may slow how your body clears drugs that depend on the CYP3A4 enzyme — a Moderate interaction affecting 633 medications. Check your prescriptions, particularly cholesterol drugs, antifungals, and any heart or blood pressure medication, with the tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're considering this for a specific health reason, talk with your pharmacist first — we don't have evidence it works for any particular condition. Before you start, especially if you take prescription medications, check them against the interaction tool below.

Pregnant or breastfeeding? Skip this one.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 25, 2011.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Black Cherry Concentrate, straight from the product label.

Brand GNC Natural Brand
Barcode (UPC) 048107074777
Net contents 120 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Nov 25, 2011
DSLD ID 2240
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Black Cherry Concentrate by GNC Natural Brand, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
UPC/BARCODE
048107074777
IngredientAmount% DV
Black Cherry concentrate500 mg--

Other ingredients: Cellulose, Maltodextrin, Vegetable Cellulose Capsule, Calcium Carbonate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

dietary supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take two capsules one to two times daily.

Precautions

KEEP OUT OF REACH OF CHILDREN

WARNING: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition. Discontinue use two weeks prior to surgery.

Storage

Store in a cool, dry place.

Formula

From ripe, wholesome cherries

General Statements

250 mg

ACTUAL SIZE

Conforms to USP <2091> for weight.

GNC

Made in the USA

Meets USP <2040> disintegration.

General

CODE 420415 HIG

Formulation

No Sugar, No Artificial Colors, No Artificial Flavors, Sodium Free, No Wheat, No Gluten, No Soy, No Dairy, Yeast Free.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Black Cherry Concentrate by GNC Natural Brand label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Black Cherry Concentrate label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Black Cherry Concentrate by GNC Natural Brand

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Black Cherry concentrate

Interacts with
643 drugs
500 mg per serving

Wild cherry bark is a traditional cough remedy found in many old-fashioned cough syrups and lozenges, but there is little modern scientific evidence p...

Black Cherry concentrate monograph & interactions

Other (inactive) ingredients: Cellulose, Maltodextrin, Vegetable Cellulose Capsule, Calcium Carbonate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Black Cherry Concentrate by GNC Natural Brand Drug Interactions

Want to check YOUR meds against Black Cherry Concentrate?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
643Drugs
643 Moderate

Ingredients driving the most interactions

Black Cherry concentrate 643

Individual Drug Interactions

The ingredients in Black Cherry Concentrate interact with 643 drugs. Click any drug to see the details.

1 of the 1 ingredient in Black Cherry Concentrate interact with drugs. Each result below shows which ingredient is responsible. Black Cherry concentrate

Each ingredient & the kinds of drugs it affects

For each ingredient in Black Cherry Concentrate with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Black Cherry concentrate1 drug type · 643 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

In vitro research suggests that wild cherry can inhibit cytochrome P450 3A4 (CYP3A4) enzymes. Theoretically, wild cherry might increase levels of drugs metabolized by CYP3A4. However, so far, this interaction has not been reported in humans.
Some drugs metabolized by CYP3A4 include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), and others.

Likelihood Possible Evidence D
Black Cherry concentrate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Black Cherry Concentrate, from the product label.

GNC Natural Brand

See all GNC Natural Brand products
Phone Number
1-888-462-2548
Pharmacist Counseling Corner

Black Cherry Concentrate by GNC Natural Brand: Common Questions

Does Black Cherry Concentrate by GNC Natural Brand interact with any medications?
Yes. Based on its ingredients, Black Cherry Concentrate has a known interaction with 643 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Black Cherry Concentrate contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is black cherry safe to take if I'm pregnant or breastfeeding?
No. The safety data advises against it during pregnancy because the plant contains cyanide-forming compounds. During breastfeeding, there isn't enough safety information, so it should be avoided.
What happens if I take too much of this product?
Large amounts of wild cherry can cause cyanide toxicity, which can be life-threatening. Symptoms include headache, nausea, vomiting, confusion, and difficulty breathing. Stick to the label dose.
Why does this product interact with so many medications?
One ingredient — wild cherry — may slow down an enzyme (CYP3A4) your liver uses to break down hundreds of different drugs. When that enzyme is blocked, those drugs can build up in your bloodstream.
Has this interaction actually happened in people taking this product?
Not that's been reported. The concern comes from laboratory studies, not from real-world cases — but it's still worth checking your medications before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Black Cherry Concentrate is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Black Cherry Concentrate label
Go deeper

The Full Monographs Behind Black Cherry Concentrate’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Wild Cherry

Interacts with 643 drugs

Wild cherry bark is a traditional cough remedy found in many old-fashioned cough syrups and lozenges, but there is little modern scientific evidence proving it works. The bark, leaves, and s...

Read the full Wild Cherry monograph →
Sources

Sources & How We Checked

Black Cherry Concentrate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Wild Cherry 4 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
  4. Pentore, R., Venneri, A., and Nichelli, P. Accidental choke-cherry poisoning: early symptoms and neurological sequelae of an unusual case of cyanide intoxication. Ital.J Neurol.Sci. 1996;17(3):233-235. PubMed

See these in context on the Wild Cherry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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