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Dietary supplement

Blue Flag Root 450 mg Ingredients & Drug Interactions

by TerraVita Premium Collection

Blue Flag Root 450 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Blue Flag Root 450 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Blue Flag Root 450 mg is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for skin conditions like acne and eczema, constipation and digestive complaints, liver and gallbladder support (traditional).Based on those ingredients, 78 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Blue Flag. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Blue Flag Root 450 mg by TerraVita Premium Collection

Ask about any prescription or over-the-counter medication and we check it for interactions with Blue Flag Root 450 mg by TerraVita Premium Collection — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Blue Flag Root 450 mg by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: blue flag root at 450 mg per capsule. Blue flag is a plant root traditionally used for its laxative properties.

The capsule itself is made from gelatin and water.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Blue Flag product and its label doesn't state a use — see Blue Flag's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The product facts don't include effectiveness ratings for blue flag root, so we don't have established evidence on file about how well it works for any condition.

The evidence, ingredient by ingredient Blue Flag

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Blue flag root can cause nausea, vomiting, and irritation of the mouth and throat, especially if the root is fresh. The volatile oils in blue flag can also irritate mucous membranes throughout your mouth, throat, and eyes, and may trigger headache or eye inflammation.

You should avoid blue flag during pregnancy because of potential toxicity and lack of safety data. It is likely unsafe while breastfeeding, so don't use it if you're nursing.

Side effects, ingredient by ingredient Blue Flag

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Blue Flag.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; heart-rhythm medications.
  • For scale: 78 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, check your medications against these: digoxin (a heart drug) — Major interaction; warfarin and other blood thinners, plus potassium-depleting diuretics — both Moderate. Your pharmacist can search your exact drugs using the tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Blue flag root is a strong stimulant laxative that works best for short-term use in people without heart conditions, bleeding disorders, or potassium concerns. If you take digoxin, warfarin, or water pills, talk to your pharmacist before starting — the interactions can be serious.

Pregnant and breastfeeding people should not use this product.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Blue Flag Root 450 mg, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064435169299
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Apr 21, 2023
DSLD ID 287591
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Blue Flag Root 450 mg by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
064435169299
IngredientAmount% DV
Blue Flag450 mg--

Other ingredients: Gelatin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2006 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions Take 1 capsule, 3 times daily, with meals.

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Blue Flag Root 450 mg by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Blue Flag Root 450 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Blue Flag Root 450 mg by TerraVita Premium Collection

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Blue Flag

Interacts with
78 drugs
450 mg per serving

Blue Flag is a flowering plant whose root has been used in traditional and herbal medicine for skin and digestive complaints, but there is very little...

Blue Flag monograph & interactions

Other (inactive) ingredients: Gelatin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Blue Flag Root 450 mg by TerraVita Premium Collection Drug Interactions

Want to check YOUR meds against Blue Flag Root 450 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
78Drugs
1 Major 77 Moderate

Ingredients driving the most interactions

Blue Flag 78

Individual Drug Interactions

The ingredients in Blue Flag Root 450 mg interact with 78 drugs. Click any drug to see the details.

1 of the 1 ingredient in Blue Flag Root 450 mg interact with drugs. Each result below shows which ingredient is responsible. Blue Flag

Each ingredient & the kinds of drugs it affects

For each ingredient in Blue Flag Root 450 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Blue Flag3 drug types · 78 drugs

Digoxin (Lanoxin)

Theoretically, overuse or abuse of this product increases the risk of adverse effects from cardiac glycoside drugs.

Likelihood Probable Evidence D
Diuretic Drugs

Overuse of blue flag might compound diuretic-induced potassium loss. There is some concern that people taking blue flag along with potassium depleting diuretics might have an increased risk for hypokalemia. Initiation of potassium supplementation or an increase in potassium supplement dose may be necessary for some patients. Some diuretics that can deplete potassium include chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, Hydrodiuril, Microzide), and others.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Blue flag has stimulant laxative effects. In some people blue flag can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of blue flag.

Likelihood Possible Evidence D
Blue Flag full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Blue Flag Root 450 mg, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Blue Flag Root 450 mg by TerraVita Premium Collection: Common Questions

Does Blue Flag Root 450 mg by TerraVita Premium Collection interact with any medications?
Yes. Based on its ingredients, Blue Flag Root 450 mg has a known interaction with 78 medications, including 1 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Blue Flag Root 450 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
No. Blue flag should be avoided during pregnancy because of potential toxicity and lack of safety data. Talk to your pharmacist or doctor about alternatives if you need a laxative.
Is it safe to breastfeed while taking blue flag?
No. Blue flag is likely unsafe while breastfeeding due to insufficient safety information. You should not use this product if you're nursing.
What side effects should I expect?
Blue flag commonly causes nausea and vomiting. It can also irritate your mouth, throat, and stomach lining, especially if the root is fresh. The volatile oils in it may cause headache, throat irritation, or eye inflammation.
Can I use this as a regular laxative?
Blue flag is a strong stimulant laxative, so it should generally be used for short-term relief only. If you need long-term help with constipation, talk to your pharmacist about gentler or safer options.
I take a water pill for my blood pressure. Is blue flag safe?
There's a moderate interaction concern. Blue flag can increase the risk of low potassium when paired with potassium-depleting diuretics, so you may need a potassium supplement adjustment. Check with your pharmacist before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Blue Flag Root 450 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Blue Flag Root 450 mg label
Go deeper

The Full Monographs Behind Blue Flag Root 450 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Blue Flag

Interacts with 78 drugs

Blue Flag is a flowering plant whose root has been used in traditional and herbal medicine for skin and digestive complaints, but there is very little modern scientific evidence to support t...

Read the full Blue Flag monograph →
Sources

Sources & How We Checked

Blue Flag Root 450 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Blue Flag 3 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

See these in context on the Blue Flag monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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